期刊
RHEUMATOLOGY
卷 54, 期 11, 页码 2015-2024出版社
OXFORD UNIV PRESS
DOI: 10.1093/rheumatology/kev201
关键词
systemic sclerosis; scleroderma; digital vasculopathy; Raynaud's phenomenon; digital ulcer; critical digital ischaemia
类别
Objective. Digital vasculopathy (comprising RP, digital ulceration and critical digital ischaemia) is responsible for much of the pain and disability experienced by patients with SSc. However, there is a limited evidence base to guide clinicians in the management of SSc-related digital vasculopathy. Our aim was to produce recommendations that would be helpful for clinicians, especially for those managing patients outside specialist centres. Methods. The UK Scleroderma Study Group set up several working groups to develop a number of consensus best practice pathways for the management of SSc-specific complications, including digital vasculopathy. Results. This overview presents the background and best practice consensus pathways for SSc-related RP, digital ulceration and critical ischaemia. Examples of drug therapies, including doses, are suggested in order to inform prescribing practice. Conclusion. A number of treatment algorithms are provided that are intended to provide the clinician with accessible reference tools for use in daily management.
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