Article
Radiology, Nuclear Medicine & Medical Imaging
Ieun Yoon, Jae Seok Bae, Jeongin Yoo, Dong Ho Lee, Se Hyung Kim
Summary: Studies suggest that compared to MDCT alone, MDCT combined with [F-18]FDG PET/MRI can improve the diagnostic accuracy for preoperative M staging and resectability in patients with recurrent gastric cancer, with a significant advantage in evaluating M staging.
EUROPEAN RADIOLOGY
(2021)
Review
Radiology, Nuclear Medicine & Medical Imaging
Sangwon Han, Joon Young Choi
Summary: The systematic review and meta-analysis found that the use of F-18-FDG PET, PET/CT, or PET/MRI during the initial staging of breast cancer can significantly modify staging and treatment plans for patients. Factors such as age, initial stage, and histologic grade were identified as significant factors affecting the heterogeneity in changes in stage or management. Routine clinical use of PET imaging for initial staging of breast cancer may be beneficial based on current literature.
CLINICAL NUCLEAR MEDICINE
(2021)
Article
Oncology
Cornelis M. de Mooij, Thiemo J. A. van Nijnatten, Briete Goorts, Loes F. S. Kooreman, Isabel W. M. Raymakers, Silke P. L. van Meijl, Maaike de Boer, Kristien B. M. I. Keymeulen, Joachim E. Wildberger, Felix M. Mottaghy, Marc B. I. Lobbes, Marjolein L. Smidt
Summary: This study investigated the feasibility of sequential hybrid [18F]FDG PET/MRI in predicting the treatment response in breast cancer patients undergoing neoadjuvant chemo(targeted) therapy. The qualitative or quantitative evaluation of PET/MRI after therapy was found to be unreliable in predicting the response of the primary tumor and axillary lymph nodes. However, combining the relative decrease in PET and MR imaging variables halfway through therapy improved the diagnostic accuracy, especially for predicting the response of axillary lymph nodes. These findings suggest that sequential hybrid [18F]FDG PET/MRI may have complementary value in the early prediction of treatment response in breast cancer.
Article
Radiology, Nuclear Medicine & Medical Imaging
Kazuhiro Kitajima, Tomoko Higuchi, Yukie Fujimoto, Eri Ishikawa, Hiroyuki Yokoyama, Hisashi Komoto, Yoshie Inao, Koichiro Yamakado, Yasuo Miyoshi
Summary: This study investigates the relationship between FDG uptake (SUVmax) and immune markers (TILs and NLR) in breast cancer patients, and evaluates the prognostic value of any correlations. Data from 502 patients who underwent surgery were reviewed, and the relationships between clinicopathological factors, SUVmax, TILs, NLR, recurrence-free survival (RFS), and overall survival were evaluated. The results indicate that FDG uptake may be predictive of immunological features and aggressive features in breast cancer patients.
EUROPEAN JOURNAL OF RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Niels W. Schurink, Simon R. van Kranen, Maaike Berbee, Wouter van Elmpt, Frans C. H. Bakers, Sander Roberti, Joost J. M. van Griethuysen, Lisa A. Min, Max J. Lahaye, Monique Maas, Geerard L. Beets, Regina G. H. Beets-Tan, Doenja M. J. Lambregts
Summary: In imaging-based prediction models, local texture analysis has potential added value compared to global tumor features to predict response. However, when combined with clinical baseline parameters such as cTN-stage, the added value of local texture analysis appears to be limited. The overall performance to predict response when combining baseline variables with quantitative imaging parameters is promising and warrants further research.
EUROPEAN RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Sangwon Han, Yong-il Kim, Jungsu S. Oh, Seung Yeon Seo, Min-Jae Park, Geun Dong Lee, Sehoon Choi, Hyeong Ryul Kim, Yong-Hee Kim, Dong Kwan Kim, Seung-Il Park, Jin-Sook Ryu
Summary: The study evaluated the diagnostic and prognostic value of pretreatment 2-[F-18]FDG PET/CT in TETs patients. The results showed that SUVmax was excellent in distinguishing thymic carcinoma from other subtypes (low-risk thymoma, high-risk thymoma) and had significant prognostic value for predicting TC.
EUROPEAN RADIOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Gaetan Van Simaeys, Gilles Doumont, Coraline De Maeseneire, Nicolas Passon, Simon Lacroix, Cedric Lentz, Arnaud Horion, Corentin Warnier, David Torres, Corentin Martens, Irina Vierasu, Dominique Egrise, Serge Goldman
Summary: This preclinical study evaluated the changes in PSMA expression in CRPC tumors following standard treatment using [F-18]JK-PSMA-7 PET/CT. The results showed that PSMA expression decreased in tumor cells after successive ADT and chemotherapy, leading to a reduction in [F-18]JK-PSMA-7 PET uptake. Caution should be exercised when using PSMA-based imaging for therapy monitoring in CRPC patients.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2021)
Review
Oncology
Federica Matteucci, Giovanni Paganelli, Giovanni Martinelli, Claudio Cerchione
Summary: Recent advances in the diagnosis and treatment of multiple myeloma have emphasized the importance of imaging methods, particularly PET/CT, in providing accurate information for disease localization, prognosis, and therapy response evaluation. While 18F-FDG tracer is commonly used and has high sensitivity, limitations such as physiological uptake in the bone marrow and brain have prompted research on other PET tracers for improved accuracy in multiple myeloma management.
FRONTIERS IN ONCOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yoshiharu Ohno, Masao Yui, Daisuke Takenaka, Takeshi Yoshikawa, Hisanobu Koyama, Yoshimori Kassai, Kaori Yamamoto, Yuka Oshima, Nayu Hamabuchi, Satomu Hanamatsu, Yuki Obama, Takahiro Ueda, Hirotaka Ikeda, Hidekazu Hattori, Kazuhiro Murayama, Hiroshi Toyama
Summary: cDWI with a b-value of 600 sec/mm² may improve the accuracy of lymph node staging in NSCLC patients compared to aDWI, STIR, and PET/CT.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2023)
Article
Biochemistry & Molecular Biology
Hyein Ahn, Geum Jong Song, Si-Hyong Jang, Myoung Won Son, Hyun Ju Lee, Moon-Soo Lee, Ji-Hye Lee, Mee-Hye Oh, Geum Cheol Jeong, Jong Hyuk Yun, Sang Mi Lee, Jeong Won Lee
Summary: This study assessed the relationship between histopathological and textural features of perigastric adipose tissue on PET/CT and found that these features were significant prognostic factors for predicting recurrence-free survival in gastric cancer patients.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Wan-Ming Chen, Mingchih Chen, Jeng-Guan Hsu, Tian-Shyug Lee, Ben-Chang Shia, Szu-Yuan Wu
Summary: The use of preoperative PET/CT is associated with a lower risk of death in patients with resectable stage IIIA-IIIB non-small cell lung cancer, but it does not improve survival rates in patients with stage I-II cancer.
Article
Medicine, General & Internal
Sebastian Werner, Julia Sekler, Brigitte Gueckel, Christian la Fougere, Konstantin Nikolaou, Christina Pfannenberg, Heike Preibsch, Tobias Engler, Susann-Cathrin Olthof
Summary: This study analyzed the impact of PET/CT on clinical management decisions in breast cancer patients. The results showed that PET/CT significantly influenced management changes, providing more reliable tumor staging and avoiding unnecessary diagnostic tests.
Article
Radiology, Nuclear Medicine & Medical Imaging
Kai Jannusch, Janna Morawitz, Bernd Schweiger, Daniel Weiss, Lars Schimmoeller, Peter Minko, Ken Herrmann, Wolfgang P. Fendler, Harald H. Quick, Gerald Antoch, Lale Umutlu, Julian Kirchner, Nils-Martin Bruckmann
Summary: The study evaluated the influence of an MRI contrast agent application on staging in pediatric lymphoma patients using [F-18]FDG PET/MRI. The results showed that the use of MRI contrast agents did not provide any benefit in the primary and follow-up staging of pediatric lymphoma patients, suggesting that a contrast agent-free [F-18]FDG PET/MRI protocol should be considered.
EUROPEAN RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Kristine E. Fasmer, Ankush Gulati, Julie A. Dybvik, Kari S. Wagner-Larsen, Njal Lura, Oyvind Salvesen, David Forsse, Jone Trovik, Johanna M. A. Pijnenborg, Camilla Krakstad, Ingfrid S. Haldorsen
Summary: This study evaluated the diagnostic performance of four different preoperative imaging workups for predicting lymph node metastases in endometrial cancer. The results showed that selective use of [F-18]FDG-PET/CT in patients with high-risk MRI findings detected lymph node metastases better than MRI alone.
EUROPEAN RADIOLOGY
(2023)
Article
Multidisciplinary Sciences
Ou Yamaguchi, Kyoichi Kaira, Ichiro Naruse, Yukihiro Umeda, Takeshi Honda, Satoshi Watanabe, Kosuke Ichikawa, Kazunari Tateishi, Norimitsu Kasahara, Tetsuya Higuchi, Kosuke Hashimoto, Shun Shinomiya, Yu Miura, Ayako Shiono, Atsuto Mouri, Hisao Imai, Kunihiko Iizuka, Tamotsu Ishizuka, Koichi Minato, Satoshi Suda, Hiroshi Kagamu, Keita Mori, Ichiei Kuji, Nobuhiko Seki
Summary: This study aimed to investigate the clinical relevance of F-18-FDG PET/CT compared to CT in predicting the response to PD-1 blockade in the early phase. The results showed that metabolic assessment by MTV or TLG was superior to morphological changes on CT for predicting the therapeutic response and survival.
SCIENTIFIC REPORTS
(2022)
Article
Oncology
Jose M. Quintana, Ane Anton-Ladisla, Nerea Gonzalez, Santiago Lazaro, Marisa Bare, Nerea Fernandez de Larrea, Maximino Redondo, Eduardo Briones, Antonio Escobar, Cristina Sarasqueta, Susana Garcia-Gutierrez
Article
Surgery
Javier Mar, Ane Anton-Ladislao, Oliver Ibarrondo, Arantzazu Arrospide, Santiago Lazaro, Nerea Gonzalez, Marisa Bare, Daniel Callejo, Maximino Redondo, Jose M. Quintana
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2018)
Article
Health Care Sciences & Services
Jose M. Quintana, Cristobal Esteban, Irantzu Barrio, Susana Garcia-Gutierrez, Nerea Gonzalez, Inmaculada Arostegui, Iratxe Lafuente, Marisa Bare, Juan Antonio Blasco, Silvia Vidal
BMC HEALTH SERVICES RESEARCH
(2011)
Article
Ophthalmology
J. M. Quintana, S. Garcia, U. Aguirre, N. Gonzalez, E. Arteta, A. Escobar, M. Bare, J. A. Blasco, J. Martinez-Tapias
Article
Primary Health Care
Beatriz Valentin-Lopez, Juan Ferrandiz-Santos, Juan-Antonio Blasco-Amaro, Juan-Diego Morillas-Sainz, Pedro Ruiz-Lopez
Article
Health Care Sciences & Services
Fatima Izquierdo, Javier Gracia, Mercedes Guerra, Juan Antonio Blasco, Elena Andradas
INTERNATIONAL JOURNAL OF TECHNOLOGY ASSESSMENT IN HEALTH CARE
(2011)
Article
Health Care Sciences & Services
Leonor Varela-Lema, Alberto Ruano-Ravina, Teresa Cerda Mota, Nora Ibargoyen-Roteta, Inaki Imaz, Inaki Gutierrez-Ibarluzea, Juan Antonio Blasco-Amaro, Enrique Soto-Pedre, Laura Sampietro-Colom
INTERNATIONAL JOURNAL OF TECHNOLOGY ASSESSMENT IN HEALTH CARE
(2012)
Article
Infectious Diseases
S. Garcia-Gutierrez, J. M. Quintana, U. Aguirre, C. Esteban, A. Bilbao, A. Escobar, S. Vidal, M. Bare, F. Aizpuru, J. A. Blasco
INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE
(2011)
Article
Infectious Diseases
S. Vidal, N. Gonzalez, I. Barrio, F. Rivas-Ruiz, M. Bare, J. A. Blasco, C. Ruiz-Frutos, J. M. Quintana
INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE
(2013)
Article
Health Care Sciences & Services
Cesar Llorente, Juan A. Blasco, Jose M. Quintana, Amaia Bilbao, Txomin Alberdi, Juan R. Lacalle, Jose M. Begiristain, Marisa Bare
JOURNAL OF EVALUATION IN CLINICAL PRACTICE
(2011)
Article
Cardiac & Cardiovascular Systems
Paz Catalan, Daniel Callejo, Juan Antonio Blasco
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2013)
Review
Allergy
Jose-Maria Maesa, Agnieszka Dobrzynska, Elena Banos-Alvarez, Rebeca Isabel-Gomez, Juan-Antonio Blasco-Amaro
Summary: This systematic review aimed to assess the diagnostic accuracy of ImmunoCAP ISAC compared to oral food challenge. The study found that the specificity of ISAC components was generally higher than sensitivity, highlighting the need for higher quality information to determine the clinical utility of ISAC in diagnosing food allergies.
CLINICAL AND EXPERIMENTAL ALLERGY
(2021)
Review
Ophthalmology
Jose-Maria Maesa, Elena Banos-Alvarez, Maria-Piedad Rosario-Lozano, Juan-Antonio Blasco-Amaro
Summary: This study conducted a systematic review and meta-analysis to compare the diagnostic accuracy of OCTA and FA in identifying choroidal neovascularization due to AMD, finding no superiority of OCTA over FA. The use of OCTA as a supportive technique could potentially improve patient flow and reduce the number of FA procedures.
ACTA OPHTHALMOLOGICA
(2022)
Article
Health Policy & Services
Alvaro Hidalgo-Vega, Renata Villoro, Juan Antonio Blasco, Pablo Talavera, Belen Ferro, Oana Purcaru
COST EFFECTIVENESS AND RESOURCE ALLOCATION
(2015)
Article
Radiology, Nuclear Medicine & Medical Imaging
Nieves Gomez Leon, Sofia Escalona, Beatriz Bandres, Cristobal Belda, Daniel Callejo, Juan Antonio Blasco
RADIOLOGY RESEARCH AND PRACTICE
(2014)