期刊
MEDICAL MYCOLOGY
卷 49, 期 5, 页码 495-499出版社
OXFORD UNIV PRESS
DOI: 10.3109/13693786.2010.541949
关键词
antifungal agents; in vitro susceptibility testing; onychomycosis
资金
- Escola Universitaria d'infermeria
Due to the increase of choices relative to antifungals, there is a need to improve the standardization of in vitro methods used to determine the antifungal susceptibility of fungal pathogens. Our study evaluated the in vitro susceptibility of filamentous fungi isolated from patients with toenail onychomycosis against itraconazole, ciclopirox, eberconazole, fluconazole and terbinafine. The minimum inhibitory concentration (MIC) of these antifungal agents was determined with 100 isolates, including dermatophytes (70 strains) and non-dermatophyte molds (30 strains). The susceptibility of fungal isolates was measured by using a technique modified for dermatophytes (0.5 x 10
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