Article
Urology & Nephrology
Patrick Ahearn, Kirsten L. Johansen, Jane C. Tan, Charles E. McCulloch, Barbara A. Grimes, Elaine Ku
Summary: Women with kidney failure have lower access to kidney transplantation compared with men, especially notable among patients with kidney failure attributed to diabetes, while sex disparities in access to either the waitlist or transplantation were not observed in kidney failure secondary to cystic disease.
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2021)
Editorial Material
Urology & Nephrology
Jaquelyne T. Hughes
Summary: Strengthening genuine and committed partnerships between the Australian government, health-care providers and Aboriginal and Torres Strait Islander peoples is crucial for achieving the goal of reducing the inequitable burden of kidney disease.
NATURE REVIEWS NEPHROLOGY
(2021)
Article
Urology & Nephrology
Elaine Ku, Sandra Amaral, Charles E. McCulloch, Deborah B. Adey, Libo Li, Kirsten L. Johansen
Summary: This study examines whether using the 2021 CKD-EPI equation can reduce racial differences in preemptive wait time for kidney transplantation.
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2022)
Article
Neurosciences
Michael Waller, Rachel F. Buckley, Colin L. Masters, Francis R. Nona, Sandra J. Eades, Annette J. Dobson
Summary: This study compared dementia mortality rates between Indigenous and non-Indigenous Australians using data from 2006 to 2014. It found that Indigenous Australians had a 57% higher rate of death with dementia, especially at younger ages, and were more likely to have their dementia coded as 'unspecified' on their death certificate.
JOURNAL OF ALZHEIMERS DISEASE
(2021)
Review
Urology & Nephrology
Clodagh Cogley, Claire Carswell, Kate Bramham, Joseph Chilcot
Summary: Individuals with severe mental illness have a higher risk of developing chronic kidney disease, partly due to known risk factors such as lithium treatment and cardiovascular disease. However, the reasons for the higher proportion of chronic kidney disease in this population still require further research. Similarly, there is a lack of data on the rates of severe mental illness in individuals with chronic kidney disease. Furthermore, individuals with severe mental illness and chronic kidney disease have poorer health outcomes and receive suboptimal kidney care. Education and closer collaboration between kidney healthcare staff and psychiatry may improve care for this population.
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2022)
Article
Medicine, General & Internal
Mark K. Tiong, Sajan Thomas, David K. Fernandes, Sajiv Cherian
Summary: Indigenous Australians face significant delays in accessing the kidney transplant waitlist, with cardiac assessment and systems issues being the major sources of delay.
INTERNAL MEDICINE JOURNAL
(2022)
Article
Urology & Nephrology
Rachel E. E. Patzer, Rebecca Zhang, Jade Buford, Laura McPherson, Yi-Ting Hana Lee, Megan Urbanski, Dong Li, Adam Wilk, Sudeshna Paul, Laura Plantinga, Cam Escoffery, Stephen O. O. Pastan
Summary: The effectiveness of an educational and outreach intervention targeting US dialysis facilities with low waitlisting was assessed. The intervention aimed to increase waitlisting and reduce racial disparities in waitlisting. The results showed that the intervention had a small effect on attenuating racial disparities in waitlisting among the targeted dialysis facilities.
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2023)
Article
Urology & Nephrology
Jill Krissberg, Matthew Kaufmann, Anshal Gupta, Eran Bendavid, Margaret Stedman, Xingxing Cheng, Jane Tan, Paul Grimm, Abanti Chaudhuri
Summary: The study assessed the impact of the 2014 Kidney Allocation System (KAS) policy change on racial and ethnic disparities in pediatric kidney transplantation access and outcomes. Results showed that all children experienced longer wait times for transplantation post-KAS implementation, but disparities in wait times among racial and ethnic groups were reduced after the implementation of KAS.
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Ingrid Stacey, Rebecca Seth, Lee Nedkoff, Joseph Hung, Vicki Wade, Emma Haynes, Jonathan Carapetis, Kevin Murray, Dawn Bessarab, Judith M. Katzenellenbogen
Summary: The study aimed to generate contemporary age-specific mortality rates for Indigenous and non-Indigenous Australians aged <65 years who died from rheumatic heart disease (RHD) between 2013 and 2017, and to ascertain the underlying causes of death of a prevalent RHD cohort. The results showed that RHD mortality rates varied among different age groups and there were other cardiovascular and non-cardiovascular conditions as the underlying causes of death for a significant portion of the RHD cohort.
Review
Ophthalmology
Mark A. Chia, Joshua R. Taylor, Kelsey V. Stuart, Anthony P. Khawaja, Paul J. Foster, Pearse A. Keane, Angus W. Turner
Summary: This study provides a systematic review and meta-analysis of the prevalence of diabetic retinopathy (DR) among Indigenous and non-Indigenous Australians. The findings indicate a higher prevalence of DR, diabetic macular edema (DME), and vision-threatening DR (VTDR) in the Indigenous subgroup compared to the non-Indigenous subgroup. Methodological weaknesses in Indigenous studies may contribute to the underestimation of disease burden.
Article
Surgery
Robert M. Cannon, Douglas J. Anderson, Paul MacLennan, Babak J. Orandi, Saulat Sheikh, Vineeta Kumar, Michael J. Hanaway, Jayme E. Locke
Summary: There is a significant mismatch between kidney transplant rates and the burden of end-stage kidney disease (ESKD) in the United States. Areas with the highest ESKD burden have the lowest transplant rates, exacerbating pre-existing disparities in access to care and overall community health.
Article
Infectious Diseases
Sushma Dahal, Svenn-Erik Mamelund, Ruiyan Luo, Lisa Sattenspiel, Shannon Self-Brown, Gerardo Chowell
Summary: This study investigated COVID-19 mortality in indigenous and non-indigenous populations in Mexico. The findings showed that indigenous populations had a higher mortality rate compared to non-indigenous groups. The fourth wave of the pandemic had the highest mortality rate. After controlling for other factors, indigenous status remained a significant risk factor for COVID-19 mortality. These findings may indicate disparities in non-pharmaceutical interventions and vaccination coverage between indigenous and non-indigenous populations.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2022)
Article
Urology & Nephrology
Catherine Zheng, Armando Teixeira-Pinto, Jaquelyne T. Hughes, Victoria Sinka, Anita van Zwieten, Wai H. Lim, Germaine Wong
Summary: Compared to non-Indigenous Australians, Indigenous Australians have a higher risk of acute rejection, infection-related death, and all-cause death after kidney transplantation. Acute rejection partially mediates the relationship between Indigenous status and graft loss, but is not associated with infection-related death.
KIDNEY INTERNATIONAL REPORTS
(2022)
Article
Urology & Nephrology
Lucy A. Plumb, Manish D. Sinha, Anna Casula, Carol D. Inward, Stephen D. Marks, Fergus J. Caskey, Yoav Ben-Shlomo
Summary: The study found that socioeconomic deprivation and geographic location are not associated with late presentation in children in the UK. While geographic location was not independently associated with preemptive transplantation, children from more affluent areas were more likely to receive a preemptive transplant.
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2021)
Article
Surgery
Aaron M. Delman, Kevin M. Turner, Latifa S. Silski, Ralph C. Quillin, Martha Estrada, Kristina Lemon, Madison C. Cuffy, Shimul A. Shah
Summary: This study developed a scalable metric to evaluate the performance of kidney transplant centers in providing equitable access to kidney transplant for minority patients. The results showed significant variations among transplant centers, with high KTEI centers performing more kidney transplants for minority and low socioeconomic status patients and having improved patient survival.
Article
Medicine, General & Internal
Amy Kang, Louisa Sukkar, Carinna Hockham, Min Jun, Tamara Young, Anish Scaria, Celine Foote, Brendon L. Neuen, Alan Cass, Carol Pollock, Elizabeth Comino, Thomas Lung, Roberto Pecoits-Filho, Kris Rogers, Meg J. Jardine
Summary: This large population-based study found that multiple factors, including age, residential area, smoking, obesity, diabetes, hypertension, coronary heart disease, depression/anxiety, and cancer, were independently associated with the development of CKD. Migrants were less likely to develop CKD compared to those born in Australia.
INTERNAL MEDICINE JOURNAL
(2022)
Article
Transplantation
Edward Zimbudzi, Clement Lo, Sanjeeva Ranasinha, Arul Earnest, Helena Teede, Tim Usherwood, Kevan R. Polkinghorne, Gregory Fulcher, Martin Gallagher, Stephen Jan, Alan Cass, Rowan Walker, Grant Russell, Greg Johnson, Peter G. Kerr, Sophia Zoungas
Summary: This study evaluated the impact of a diabetes and kidney disease service on hospitalization, mortality, and clinical outcomes. The results showed that patients who received the intervention had higher hospitalization rates, shorter length of stay, and lower all-cause mortality rates. Additionally, improvements in self-care and glycemic control were observed in the intervention group.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2022)
Article
Medicine, General & Internal
Namrata Khanal, Paul D. Lawton, Alan Cass, Stephen P. McDonald
INTERNAL MEDICINE JOURNAL
(2023)
Article
Nutrition & Dietetics
Marguerite Conley, Anne Barden, Andrea K. Viecelli, Ashley B. Irish, Alan Cass, Carmel M. Hawley, David Voss, Elaine M. Pascoe, Katie Lenhoff, Kevan R. Polkinghorne, Lai-Seong Hooi, Loke-Meng Ong, Peta-Anne Paul-Brent, Peter G. Kerr, Trevor A. Mori
Summary: This study investigated the dietary habits of patients with kidney failure in Australia, New Zealand, and Malaysia. The findings showed significant regional variation in the intake of fruits, vegetables, and animal protein, which may be attributed to cultural and economic differences. Further research is needed to identify barriers to meeting recommended dietary intakes in different regions.
JOURNAL OF HUMAN NUTRITION AND DIETETICS
(2022)
Article
Health Care Sciences & Services
Gillian Gorham, Kirsten Howard, Joan Cunningham, Paul Damian Lawton, A. M. Shamsir Ahmed, Federica Barzi, Alan Cass
Summary: Aboriginal people in the Northern Territory of Australia, especially those living in remote areas, face a heavy burden of kidney failure. Due to a lack of dialysis services in these remote areas, many Aboriginal people are required to relocate to access treatment. This study explores the relationship between the location of dialysis services, dialysis attendance patterns, and health service utilization among Aboriginal patients in the Northern Territory. The findings suggest that missing dialysis treatments is more common among Aboriginal people attending urban services, resulting in higher rates of hospital admissions and emergency department presentations. On the other hand, those receiving care in rural and remote settings have higher dialysis attendance and lower health service utilization. The study concludes that access to rural and remote models of care can potentially improve dialysis attendance and reduce the need for hospitalization among Aboriginal patients.
BMC HEALTH SERVICES RESEARCH
(2022)
Article
Medicine, General & Internal
Jicheng Lv, Muh Geot Wong, Michelle A. Hladunewich, Vivekanand Jha, Lai Seong Hooi, Helen Monaghan, Minghui Zhao, Sean Barbour, Meg J. Jardine, Heather N. Reich, Daniel Cattran, Richard Glassock, Adeera Levin, David C. Wheeler, Mark Woodward, Laurent Billot, Sandrine Stepien, Kris Rogers, Tak Mao Chan, Zhi-Hong Liu, David W. Johnson, Alan Cass, John Feehally, Jurgen Floege, Giuseppe Remuzzi, Yangfeng Wu, Rajiv Agarwal, Hong Zhang, Vlado Perkovic
Summary: This international multicenter randomized clinical trial found that oral methylprednisolone significantly reduced the risk of kidney function decline, kidney failure, or death due to kidney disease in patients with IgA nephropathy at high risk of progression. However, it also increased the incidence of serious adverse events.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2022)
Article
Transplantation
Sradha Kotwal, Sanjeeva Herath, Jonathan Erlich, Sally Boardman, Jennifer Qian, Paul Lawton, Craig Campbell, Andrew Whatnall, Su Teo, A. Rita Horvath, Zoltan H. Endre
Summary: This study demonstrates the potential benefits of early recognition of hospital-acquired acute kidney injury (AKI) in improving patient management and outcomes. Implementation of an intervention bundle may reduce length of stay and improve documentation of AKI and other management measures.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2023)
Article
Medicine, General & Internal
Sradha Kotwal, Alan Cass, Sarah Coggan, Nicholas A. Gray, Stephen Jan, Stephen McDonald, Kevan R. Polkinghorne, Kris Rogers, Girish Talaulikar, Gian Luca Di Tanna, Martin Gallagher
Summary: This study indicates that implementing multifaceted interventions did not reduce the rate of CRBSI among patients requiring hemodialysis catheters. Therefore, multifaceted interventions to prevent CRBSI may not be effective in clinical practice settings.
BMJ-BRITISH MEDICAL JOURNAL
(2022)
Article
Pharmacology & Pharmacy
Amy Legg, Niamh Meagher, Sandra A. Johnson, Matthew A. Roberts, Alan Cass, Marc H. Scheetz, Jane Davies, Jason A. Roberts, Joshua S. Davis, Steven Y. C. Tong
Summary: The clinical risk factors for nephrotoxicity in Staphylococcus aureus bacteraemia are still unclear. In a clinical trial comparing standard therapy to combination therapy, it was found that the combination therapy group had a significantly higher incidence of acute kidney injury.
CLINICAL DRUG INVESTIGATION
(2023)
Review
Urology & Nephrology
Benjamin Talbot, Alan Cass, Robert Walker, Lai Hooi, Meg Jardine, Min Jun, Kris Rogers, Louisa Sukkar, Brendan Smyth, Martin Gallagher
Summary: This study examined whether there were differences in survival and causes of death among participants from Australia, Malaysia, and New Zealand in the extended follow-up of the SHARP study. It was found that participants from Malaysia and New Zealand had a higher risk of death compared to participants from Australia.
Article
Urology & Nephrology
Winnie Chen, Asanga Abeyaratne, Gillian Gorham, Pratish George, Vijay Karepalli, Dan Tran, Christopher Brock, Alan Cass
Summary: This study develops and validates algorithms to identify chronic kidney disease (CKD) and related chronic diseases. The algorithms showed high diagnostic accuracy compared to traditional administrative codes, providing new opportunities for early detection, monitoring, and epidemiological research in kidney disease.
Correction
Pharmacology & Pharmacy
Amy Legg, Niamh Meagher, Sandra A. Johnson, Matthew A. Roberts, Alan Cass, Marc H. Scheetz, Jane Davies, Jason A. Roberts, Joshua S. Davis, Steven Y. C. Tong
CLINICAL DRUG INVESTIGATION
(2023)
Article
Endocrinology & Metabolism
Matthew J. L. Hare, Louise J. Maple-Brown, Jonathan E. Shaw, Jacqueline A. Boyle, Paul D. Lawton, Elizabeth L. M. Barr, Steven Guthridge, Vanya Webster, Denella Hampton, Gurmeet Singh, Roland F. Dyck, Federica Barzi
Summary: This study aimed to investigate the risk of developing chronic kidney disease (CKD) or end-stage kidney disease (ESKD) following a pregnancy complicated by gestational diabetes mellitus (GDM) or pre-existing diabetes among Aboriginal women in the Northern Territory (NT), Australia. The findings showed that Aboriginal women with GDM or pre-existing diabetes during pregnancy are at high risk of developing CKD and ESKD.