Article
Ornithology
Landon R. Jones, Hal L. Black, Melanie R. Boudreau, Rebecca D. Bracken, N. Paul Johnston
Summary: According to the study, when birds lack calcium, the protoporphyrin pigment deposited at weak spots in the eggshell can strengthen the structure. This hypothesis was tested on Common Pheasants, which produce pigmented eggs with a uniform ground color. The results showed that pheasants on a low-calcium diet produced eggs with more protoporphyrin-based coloration, suggesting that pigmentation serves as a structural function for eggshells when calcium is limited.
Review
Neurosciences
Ranjana Poddar
Summary: Hyperhomocysteinemia, a common metabolic disorder, is considered a risk factor for ischemic stroke, but it is unclear whether predisposition to this disorder affects the severity of stroke outcome. Current research focuses on the advantages and limitations of rodent models, the impact of mild hyperhomocysteinemia on ischemic brain damage, and the mechanisms of homocysteine-induced neurotoxicity. These findings provide insight into hyperhomocysteinemia as a comorbidity for ischemic stroke and its implications for potential therapeutic agents.
EXPERIMENTAL NEUROLOGY
(2021)
Article
Health Care Sciences & Services
Nicolas Banholzer, Stefan Feuerriegel, Elgar Fleisch, Georg Friedrich Bauer, Tobias Kowatsch
Summary: The study found that self-reported acute stress is associated with computer mouse movements, specifically in the form of a speed-accuracy trade-off. This suggests that regular analysis of computer mouse movements could indicate work stress.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2021)
Article
Biochemistry & Molecular Biology
Narsa M. Reddy, Chandra Mohan Tamatam, Ankireddy Aparna, Sekhar P. Reddy
Summary: Recognition and clearance of apoptotic cells by phagocytes, mediated primarily by macrophages, are crucial for lung inflammatory responses and tissue repair. The Nrf2 transcription factor plays a critical role in this process. This study found that Nrf2 deficiency impairs the ability of macrophages to clear apoptotic neutrophils, and activating Nrf2 may accelerate the clearance of apoptotic cells after oxidant injury.
Article
Biodiversity Conservation
Mikhail V. Kozlov, Vitali Zverev, Elena L. Zvereva
Summary: This study compared the sensitivity of leaf fluctuating asymmetry (FA) and leaf size to simulated herbivory stress. The results showed that leaf size was a more sensitive indicator of stress compared to leaf FA. Additionally, the study emphasized the importance of publishing "negative" or inconclusive results to overcome publication bias.
ECOLOGICAL INDICATORS
(2022)
Review
Biochemistry & Molecular Biology
Agnieszka Wolnicka-Glubisz, Anna Wisniewska-Becker
Summary: Curcumin, a natural polyphenol with antioxidant properties, can have therapeutic effects on different disorders. However, it can also be toxic under certain conditions, such as exposure to blue light or excessive use.
Article
Biochemistry & Molecular Biology
Marianna Miliaraki, Panagiotis Briassoulis, Stavroula Ilia, Kalliopi Michalakakou, Theodoros Karakonstantakis, Aikaterini Polonifi, Kalliopi Bastaki, Efrossini Briassouli, Konstantinos Vardas, Aikaterini Pistiki, Maria Theodorakopoulou, Theonymfi Tavladaki, Anna-Maria Spanaki, Eumorfia Kondili, Helen Dimitriou, Maria Venihaki, Sotirios Tsiodras, Dimitrios Georgopoulos, Marina Mantzourani, Serafeim Nanas, Apostolos Armaganidis, George L. Daikos, Ioannis Papassotiriou, George Briassoulis
Summary: Oxidative stress plays a crucial role in the pathophysiology of sepsis. This study investigates whether an imbalance between oxidants and antioxidants can serve as an independent discriminator and mortality predictor for septic patients. The results show that septic patients have elevated oxidant/antioxidant ratios, which are associated with severity of illness, inflammatory responses, and apoptosis-related factors.
Article
Environmental Sciences
Dominik Thom, Anthony R. Taylor, Rupert Seidl, Wilfried Thuiller, Jiejie Wang, Mary Robideau, William S. Keeton
Summary: Our study fills knowledge gaps by mapping current FD distribution and analyzing FD drivers across northeastern North America. We identified temperate forests and the boreal-temperate ecotone east and northeast of the Great Lakes as FD hotspots, with forest structure explaining most of the FD distribution of tree species in northeastern North America.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Medicine, Research & Experimental
Yoshikazu Kuwahara, Kazuo Tomita, Mehryar Habibi Roudkenar, Amaneh Mohammadi Roushandeh, Yusuke Urushihara, Kento Igarashi, Akihiro Kurimasa, Tomoaki Sato
Summary: The study revealed that modulation of mitochondrial function is implicated in the radioresistance phenotype of cancer cells, and radioresistance of clinically relevant radioresistant cells is reversible. Further studies are needed to clarify the mechanisms underlying cancer cell radioresistance.
Article
Immunology
Yasemin Ogul, Fatma Gur, Mustafa Cengiz, Bahri Gur, Refik Ali Sari, Ahmet Kiziltunc
Summary: This study evaluated the oxidant and anti-oxidant levels of RA patients and their impacts on disease activity through in silico studies. Results showed increased oxidative stress, weakened defense system, and increased ROS production in RA patients. Additionally, molecular docking studies confirmed the results on SOD and CAT activity.
INTERNATIONAL IMMUNOPHARMACOLOGY
(2021)
Article
Business, Finance
Rafael B. De Rezende
Summary: The banking crisis in early 2023 has caused turmoil in the financial markets. The failure of Silicon Valley Bank has raised concerns about the stability of other financial institutions amidst a period of monetary contraction and high interest rates. By introducing a new bank stress indicator based on an event study framework, I identify six highly stressed banks and discuss the potential risks they face. The new Bank Term Funding Program launched by the Fed aims to lower the risk of further failures.
FINANCE RESEARCH LETTERS
(2023)
Review
Pharmacology & Pharmacy
Qiao Jiang, Li Wang, Xu Si, Jin-Long Tian, Ye Zhang, Hai-Long Gui, Bin Li, De-Hong Tan
Summary: Hyperhomocysteinemia is an independent risk factor for cardiovascular diseases, and natural polyphenols can reduce homocysteine levels by acting on oxidative stress and endoplasmic reticulum stress-related signaling pathways, thus improving vascular injury caused by high homocysteine levels.
EUROPEAN JOURNAL OF PHARMACOLOGY
(2021)
Article
Psychology, Multidisciplinary
Yabo Ge, Fengying Li, Xinyu Li, Weijian Li
Summary: Interleaved practice enhances induction performance possibly due to discriminative-contrast influence. Eye-tracking data suggests that attention attenuation is not the primary mechanism underlying this interleaving effect. The results support the discriminative-contrast hypothesis over the attention attenuation hypothesis.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Biology
Amit Kumar, Manisha Vaish, Saravanan S. Karuppagounder, Irina Gazaryan, John W. Cave, Anatoly A. Starkov, Elizabeth T. Anderson, Sheng Zhang, John T. Pinto, Austin M. Rountree, Wang Wang, Ian R. Sweet, Rajiv R. Ratan
Summary: Antioxidant enzymes were not induced or increased in hypoxia, and their forced expression had varying effects on HIF1 alpha protein stability. Reduction in lipid peroxides or superoxide also did not influence HIF1 alpha protein stability. Mitochondria are suggested to contribute to hypoxic adaptation by consuming oxygen.
Article
Psychology, Mathematical
Mitchel Kappen, Kristof Hoorelbeke, Nilesh Madhu, Kris Demuynck, Marie-Anne Vanderhasselt
Summary: This study aimed to investigate the associations between speech parameters in the context of psychosocial stress, finding that the network of speech parameters remains similar before and after stress induction, with HNR playing a central role, and changes in jitter positively relating to changes in negative affect. Further longitudinal and experimental studies are needed to explore these relationships and determine causal paths in the networks.
BEHAVIOR RESEARCH METHODS
(2022)
Article
Cardiac & Cardiovascular Systems
Troy C. Sarich, Jonathan H. Seltzer, Scott D. Berkowitz, James Costin, John T. Curnutte, C. Michael Gibson, Maureane Hoffman, Edvardas Kaminskas, Mitchell W. Krucoff, Jerrold H. Levy, Paul D. Mintz, Paul A. Reilly, Philip T. Sager, Daniel E. Singer, Norman Stockbridge, Jeffrey I. Weitz, Peter R. Kowey
AMERICAN HEART JOURNAL
(2015)
Article
Anesthesiology
Maureane Hoffman, Zoya Volovyk, Dougald M. Monroe
Meeting Abstract
Hematology
Anthony D. Sung, Richard Yen, Divino Deoliveira, Yiqun Jiao, Sadhna Piryani, Alyssa Bernanke, Sharon Hall, Keith Klemp, Sangwon Yun, Gowthami Arepally, Maureane R. Hoffman, Thomas L. Ortel, Nelson J. Chao, Benny J. Chen
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
(2015)
Article
Hematology
Maureane Hoffman
SEMINARS IN THROMBOSIS AND HEMOSTASIS
(2015)
Article
Hematology
Junjiang Sun, Baolai Hua, Eric W. Livingston, Sarah Taves, Peter B. Johansen, Maureane Hoffman, Mirella Ezban, Dougald M. Monroe, Ted A. Bateman, Paul E. Monahan
Article
Hematology
M. Hoffman, J. -Y. Chang, M. Ezban, D. M. Monroe
JOURNAL OF THROMBOSIS AND HAEMOSTASIS
(2016)
Article
Hematology
A. M. Fager, K. R. Machlus, M. Ezban, M. Hoffman
JOURNAL OF THROMBOSIS AND HAEMOSTASIS
(2018)
Editorial Material
Hematology
M. Hoffman
JOURNAL OF THROMBOSIS AND HAEMOSTASIS
(2018)
Review
Hematology
Gerhard Dickneite, Maureane Hoffman
THROMBOSIS AND HAEMOSTASIS
(2014)
Article
Hematology
Maureane Hoffman, Rafal Pawlinski
THROMBOSIS RESEARCH
(2014)
Article
Hematology
Laura J. Sommerville, Kristen L. Gorman, Stacey A. Snyder, Dougald M. Monroe, Maureane Hoffman
JOURNAL OF THROMBOSIS AND HAEMOSTASIS
(2019)
Editorial Material
Hematology
Dougald Monroe, Maureane Hoffman
Editorial Material
Hematology
Maureane Hoffman
JOURNAL OF THROMBOSIS AND HAEMOSTASIS
(2022)
Article
Orthopedics
Benjamin Andress, Maureane Hoffman, Amy L. McNulty
Summary: Orthopaedic research, like biomedical research in general, has made significant progress in developing treatments for previously untreatable conditions. However, there is a concern about the quality of published research. This commentary highlights the importance of analytical validation and quality control in orthopaedic research and proposes recommendations for implementing these practices to improve research rigor and reproducibility.
JOURNAL OF ORTHOPAEDIC RESEARCH
(2023)
Review
Emergency Medicine
Maureane Hoffman, Joshua N. Goldstein, Jerrold H. Levy
INTERNATIONAL JOURNAL OF EMERGENCY MEDICINE
(2018)
Article
Medicine, Research & Experimental
Tong Cheng, Zhusheng Chen, Yibin Qin, Xiang Zhu, Hongsheng Chen, Zhongling Xu, Xiaqing Ma
Summary: Morphine is commonly used and effective for pain relief, but its side effect of itching limits its clinical use. This paper discusses the potential of using esketamine to treat morphine-induced itching.
MEDICAL HYPOTHESES
(2024)
Article
Medicine, Research & Experimental
Sung Eun Lee, Eunjung Park, Ji-yun Kim, HyukHoon Kim
Summary: Hyperbaric oxygen therapy (HBOT) is a potential therapeutic modality that has been recognized for its favorable mechanisms in various diseases, including sepsis-associated encephalopathy (SAE). HBOT has neuroprotective effects through its anti-inflammatory and antiapoptotic effects as well as increased tissue oxygenation capacity. However, there are caveats and limitations in applying HBOT in sepsis.
MEDICAL HYPOTHESES
(2024)