4.4 Article

Are Physicians With Better Clinical Skills on Licensing Examinations Less Likely to Prescribe Antibiotics for Viral Respiratory Infections in Ambulatory Care Settings?

期刊

MEDICAL CARE
卷 49, 期 2, 页码 156-165

出版社

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MLR.0b013e3182028c1a

关键词

Family physicians; physician's practice patterns; antibacterial agents; clinical competence; medical licensure

资金

  1. Medical Council of Canada (MCC)
  2. Canadian Institutes of Health Research (CIHR)

向作者/读者索取更多资源

Background: Viral respiratory infections (VRIs) are a common reason for ambulatory visits, and 35% are treated with an antibiotic. Antibiotic use for VRIs is not recommended, and it promotes antibiotic resistance. Effective patient-physician communication is critical to address this problem. Recognizing the importance of physician communication skills, licensure examinations were reformed in the United States and Canada to evaluate these skills. Objective: To assess whether physician clinical and communication skills, as measured by the Canadian clinical skills examination (CSE), predict antibiotic prescribing for VRI in ambulatory care. Research Design and Subjects: A total of 442 Quebec general practitioners and pediatricians who wrote the CSE in 1993-1996 were followed from 1993 to 2007, and their 159,456 VRI visits were identified from physician claims. Measures: The outcome was an antibiotic prescription from a study physician dispensed within 7 days of the VRI visit. Multivariate logistic regression analyses were used to estimate the association between antibiotic prescribing for VRI and CSE score, adjusting for physician, patient, and encounter characteristics. Results: Better clinical and communication skills were associated with a reduction in the risk of antibiotic prescribing, but only for female physicians. Every 1-standard deviation increase in CSE score was associated with a 19% reduction in the risk of antibiotic prescribing (risk ratio, 0.81; 95% confidence interval, 0.68-0.97). Better clinical skills were associated with an even greater reduction in risk among female physicians with higher workloads (risk ratio, 0.48; 95% confidence interval, 0.29-0.79). Conclusion: Physician clinical and communication skills are important determinants of antibiotic prescribing for VRI and should be targeted by future interventions.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.4
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

Article Public, Environmental & Occupational Health

Exposure measurement error when assessing current glucocorticoid use using UK primary care electronic prescription data

Rebecca M. Joseph, Tjeerd P. van Staa, Mark Lunt, Michal Abrahamowicz, William G. Dixon

PHARMACOEPIDEMIOLOGY AND DRUG SAFETY (2019)

Article Public, Environmental & Occupational Health

Evaluating Flexible Modeling of Continuous Covariates in Inverse-Weighted Estimators

Ryan P. Kyle, Erica E. M. Moodie, Marina B. Klein, Michal Abrahamowicz

AMERICAN JOURNAL OF EPIDEMIOLOGY (2019)

Article Public, Environmental & Occupational Health

Flexible Modeling of the Association Between Cumulative Exposure to Low-Dose Ionizing Radiation From Cardiac Procedures and Risk of Cancer in Adults With Congenital Heart Disease

Coraline Danieli, Sarah Cohen, Aihua Liu, Louise Pilote, Liming Guo, Marie-Eve Beauchamp, Ariane J. Marelli, Michal Abrahamowicz

AMERICAN JOURNAL OF EPIDEMIOLOGY (2019)

Article Mathematical & Computational Biology

Nonlinear and time-dependent effects of sparsely measured continuous time-varying covariates in time-to-event analysis

Yishu Wang, Marie-Eve Beauchamp, Michal Abrahamowicz

BIOMETRICAL JOURNAL (2020)

Article Cardiac & Cardiovascular Systems

Long-term effectiveness of catheter ablation in patients with atrial fibrillation and heart failure

Michelle Samuel, Michal Abrahamowicz, Jacqueline Joza, Marie-Eve Beauchamp, Vidal Essebag, Louise Pilote

EUROPACE (2020)

Article Mathematical & Computational Biology

Analysis of time-to-event for observational studies: Guidance to the use of intensity models

Per Kragh Andersen, Maja Pohar Perme, Hans C. van Houwelingen, Richard J. Cook, Pierre Joly, Torben Martinussen, Jeremy M. G. Taylor, Michal Abrahamowicz, Terry M. Therneau

Summary: This paper offers guidance for researchers with mathematical background on conducting time-to-event analysis based on intensity models in observational studies. It covers basic concepts like time axis, event definition, and censoring, introduces hazard models with emphasis on the Cox proportional hazards regression model, provides check lists for fitting and assessing the model's goodness of fit, and discusses avoiding immortal time bias and prediction challenges. Examples and implementation details using R software are also included.

STATISTICS IN MEDICINE (2021)

Article Peripheral Vascular Disease

SARS-CoV-2 Receptor ACE2 Gene Is Associated with Hypertension and Severity of COVID 19: Interaction with Sex, Obesity, and Smoking

Pavel Hamet, Zdenka Pausova, Redha Attaoua, Camil Hishmih, Mounsif Haloui, Jean Shin, Tomas Paus, Michal Abrhamowicz, Daniel Gaudet, Lara Santucci, Theodore A. Kotchen, Allen W. Cowley, Julie Hussin, Johanne Tremblay

Summary: The study found that a single nucleotide polymorphism of the ACE2 gene was associated with hypertension in adult obese males, especially in obese males who smoked. The variant was also linked to blood pressure levels in adolescents, with an interaction with obesity present only in females. Additionally, ACE2 gene variants were associated with more severe outcomes in COVID-19 in obese, smoking males.

AMERICAN JOURNAL OF HYPERTENSION (2021)

Article Mathematical & Computational Biology

Adapting SIMEX to correct for bias due to interval-censored outcomes in survival analysis with time-varying exposure

Michal Abrahamowicz, Marie-Eve Beauchamp, Cristiano Soares Moura, Sasha Bernatsky, Steve Ferreira Guerra, Coraline Danieli

Summary: Many applications of survival analysis focus on interval-censored events, which can lead to biased estimates. We propose a SIMEX-based correction method that improves the accuracy of estimated associations between time-varying exposures and interval-censored events.

BIOMETRICAL JOURNAL (2022)

Editorial Material Mathematical & Computational Biology

Clinical biostatistics in the 2020s

Michal Abrahamowicz

BIOMETRICAL JOURNAL (2022)

Article Rheumatology

Investigating Associations Between Access to Rheumatology Care, Treatment, Continuous Care, and Healthcare Utilization and Costs Among Older Individuals With Rheumatoid Arthritis

Claire E. H. Barber, Diane Lacaille, Ruth Croxford, Cheryl Barnabe, Deborah A. Marshall, Michal Abrahamowicz, Hui Xie, J. Antonio Avina-Zubieta, John M. Esdaile, Glen S. Hazlewood, Peter Faris, Steven Katz, Paul MacMullan, Dianne Mosher, Jessica Widdifield

Summary: This study examines the association between rheumatologist access, early treatment, and ongoing care of older-onset rheumatoid arthritis (RA) and healthcare utilization and costs following diagnosis. The results show that access to rheumatologists, timely treatment, and ongoing care are associated with lower total healthcare costs at 5 years. Investments in improving access to care may lead to long-term health system savings.

JOURNAL OF RHEUMATOLOGY (2023)

Article Rheumatology

System-level performance measures of access to rheumatology care: a population-based retrospective study of trends over time and the impact of regional rheumatologist supply in Ontario, Canada, 2002-2019

Claire E. H. Barber, Diane Lacaille, Ruth Croxford, Cheryl Barnabe, Deborah A. Marshall, Michal Abrahamowicz, Hui Xie, J. Antonio Avina-Zubieta, John M. Esdaile, Glen Hazlewood, Peter Faris, Steven Katz, Paul MacMullan, Dianne Mosher, Jessica Widdifield

Summary: The study found that although there were improvements in rheumatology care and treatment for RA patients over time, there are still shortcomings, particularly in the use of DMARDs. Patients in regions with higher rheumatologist supply were more likely to access care but less likely to receive timely treatment.

BMC RHEUMATOLOGY (2022)

Article Mathematical & Computational Biology

Comparison of cohort and nested case-control designs for estimating the effect of time-varying drug exposure on the risk of adverse event in the presence of ties

Liliane Manitchoko, Michal Abrahamowicz, Pascale Tubert-Bitter, Jacques Benichou, Anne C. M. Thiebaut

Summary: Cohort and nested case-control (NCC) designs are commonly used in pharmacoepidemiology to assess the effects of time-varying drug exposures on adverse event risks. Simulations comparing the two designs showed that cohort-based estimates had lower bias and greater precision than NCC estimates. NCC estimates showed bias that decreased with more controls per case and increased with higher event proportion, but bias was reduced when NCC analyses were matched on confounders. Overall, NCC estimates were similar to cohort-based estimates when ties were correctly accounted for.

BIOMETRICAL JOURNAL (2023)

Article Rheumatology

External Validation of the Lupus Multivariable Outcome Score for Systemic Lupus Erythematosus Trials

Michal Abrahamowicz, Maria Izabela Abrahamowicz, Peter E. Lipsky

Summary: The study developed a new Lupus Multivariable Outcome Score (LuMOS) for evaluating the treatment effectiveness of systemic lupus erythematosus (SLE). Through external validation, LuMOS demonstrated better discrimination than the SLE Responder Index-5 (SRI-5). However, further validation is needed for non-B cell-directed therapies.

ACR OPEN RHEUMATOLOGY (2022)

Article Rheumatology

A Population-Based Study Evaluating Retention in Rheumatology Care Among Patients With Rheumatoid Arthritis

Claire E. H. Barber, Diane Lacaille, Ruth Croxford, Cheryl Barnabe, Deborah A. Marshall, Michal Abrahamowicz, Hui Xie, J. Antonio Avina-Zubieta, John M. Esdaile, Glen Hazlewood, Peter Faris, Steven Katz, Paul MacMullan, Dianne Mosher, Jessica Widdifield

Summary: This study assessed adherence to system-level performance measures in rheumatology care for patients with rheumatoid arthritis (RA). The results showed a decline in the percentage of patients with annual visits over time. Factors such as age, gender, and healthcare resources were found to affect the likelihood of receiving ongoing rheumatology care.

ACR OPEN RHEUMATOLOGY (2022)

Article Mathematical & Computational Biology

Spline-based accelerated failure time model

Menglan Pang, Robert W. Platt, Tibor Schuster, Michal Abrahamowicz

Summary: A spline-based AFT model that does not require specification of the parametric family of event time distribution was developed, providing unbiased estimates and numerical stability in various scenarios.

STATISTICS IN MEDICINE (2021)

暂无数据