Pathogenic Roles of the Carotid Body Inflammation in Sleep Apnea

The human carotid body releases acetylcholine, ATP and cytokines during hypoxia

(2014) Jessica Kåhlin et al.   EXPERIMENTAL PHYSIOLOGY

Synaptic and paracrine mechanisms at carotid body arterial chemoreceptors

(2014) Colin A. Nurse   JOURNAL OF PHYSIOLOGY-LONDON

Upregulation of a local renin-angiotensin system in the rat carotid body during chronic intermittent hypoxia

(2013) Siu-Yin Lam et al.   EXPERIMENTAL PHYSIOLOGY

Intermittent hypoxia: endothelin-1 and hypoxic carotid body chemosensory potentiation

(2013) Rodrigo Iturriaga   EXPERIMENTAL PHYSIOLOGY

Obstructive Sleep Apnea and Hypertension

(2013) Tomas Konecny et al.   HYPERTENSION

Carotid body denervation improves autonomic and cardiac function and attenuates disordered breathing in congestive heart failure

(2013) Noah J. Marcus et al.   JOURNAL OF PHYSIOLOGY-LONDON

Inflammatory and immunomodulatory mechanisms in the carotid body

(2013) Andrea Porzionato et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Central and peripheral factors contributing to obstructive sleep apneas

(2013) Jan-Marino Ramirez et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Novel pharmacological approaches for treatment of obstructive sleep apnea in children

(2012) Leila Kheirandish-Gozal et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Effect of Endothelin Receptor Antagonist Bosentan on Chronic Hypoxia-Induced Inflammation and Chemoafferent Neuron Adaptation in Rat Carotid Body

(2012) Xuemei Liu et al.   HIGH ALTITUDE MEDICINE & BIOLOGY

Lower Frequency of Obstructive Sleep Apnea in Spondyloarthritis Patients Taking TNF-Inhibitors

(2012) Jessica A. Walsh et al.   Journal of Clinical Sleep Medicine

The human carotid body transcriptome with focus on oxygen sensing and inflammation - a comparative analysis

(2012) Souren Mkrtchian et al.   JOURNAL OF PHYSIOLOGY-LONDON

Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2

(2012) Nanduri R. Prabhakar et al.   PHYSIOLOGICAL REVIEWS

Chemoreceptors, baroreceptors, and autonomic deregulation in children with obstructive sleep apnea

(2012) David Gozal et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Inflammation in the carotid body during development and its contribution to apnea of prematurity

(2012) Estelle B. Gauda et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Chronic hypoxia-induced acid-sensitive ion channel expression in chemoafferent neurons contributes to chemoreceptor hypersensitivity

(2011) X. Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Differential expression of pro-inflammatory cytokines, endothelin-1 and nitric oxide synthases in the rat carotid body exposed to intermittent hypoxia

(2011) Rodrigo Del Rio et al.   BRAIN RESEARCH

Carotid body inflammation and cardiorespiratory alterations in intermittent hypoxia

(2011) Rodrigo Del Rio et al.   EUROPEAN RESPIRATORY JOURNAL

Chronic intermittent hypoxia induces local inflammation of the rat carotid body via functional upregulation of proinflammatory cytokine pathways

(2011) Siu-Yin Lam et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Angiotensin II evokes sensory long-term facilitation of the carotid body via NADPH oxidase

(2011) Ying-Jie Peng et al.   JOURNAL OF APPLIED PHYSIOLOGY

A chronic pain: Inflammation-dependent chemoreceptor adaptation in rat carotid body

(2011) X. Liu et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Immunosensory signalling by carotid body chemoreceptors

(2011) Patricio Zapata et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Ibuprofen blocks time-dependent increases in hypoxic ventilation in rats

(2011) Dan Popa et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Preliminary prospective explanatory observation on the impact of 3-month steroid therapy on the objective measures of sleep-disordered breathing

(2011) Gidon Berger et al.   Sleep and Breathing

Exacerbation of Obstructive Sleep Apnea by Oral Indomethacin

(2010) Keith R. Burgess et al.   CHEST

Neurotransmitter and neuromodulatory mechanisms at peripheral arterial chemoreceptors

(2010) Colin A. Nurse   EXPERIMENTAL PHYSIOLOGY

Pathophysiology of Sleep Apnea

(2010) Jerome A. Dempsey et al.   PHYSIOLOGICAL REVIEWS

Chronic intermittent hypoxia augments chemoreflex control of sympathetic activity: Role of the angiotensin II type 1 receptor

(2010) Noah J. Marcus et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Lipopolysaccharide signaling in the carotid chemoreceptor pathway of rats with sepsis syndrome

(2010) Ricardo Fernández et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Carotid body potentiation induced by intermittent hypoxia: Implications for cardiorespiratory changes induced by sleep apnoea

(2009) Rodrigo Iturriaga et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

NADPH Oxidase Is Required for the Sensory Plasticity of the Carotid Body by Chronic Intermittent Hypoxia

(2009) Y.- J. Peng et al.   JOURNAL OF NEUROSCIENCE

Adaptation to chronic hypoxia involves immune cell invasion and increased expression of inflammatory cytokines in rat carotid body

(2008) X. Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Lipopolysaccharide-induced carotid body inflammation in cats: functional manifestations, histopathology and involvement of tumour necrosis factor-α

(2008) Ricardo Fernández et al.   EXPERIMENTAL PHYSIOLOGY

Chronic hypoxia upregulates the expression and function of proinflammatory cytokines in the rat carotid body

(2008) Siu-Yin Lam et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Interdependent roles for hypoxia inducible factor and nuclear factor-κB in hypoxic inflammation

(2008) Cormac T. Taylor   JOURNAL OF PHYSIOLOGY-LONDON

NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α

(2008) Jordi Rius et al.   NATURE

Cytokines and pathological sleep

(2007) Fotis Kapsimalis et al.   SLEEP MEDICINE