IRF5 Is a Specific Marker of Inflammatory MacrophagesIn Vivo

Characterization of Macrophage Phenotypes in Three Murine Models of House-Dust-Mite-Induced Asthma

(2013) Christina Draijer et al.   MEDIATORS OF INFLAMMATION

Tissue-resident macrophages

(2013) Luke C Davies et al.   NATURE IMMUNOLOGY

Distinct bone marrow-derived and tissue-resident macrophage lineages proliferate at key stages during inflammation

(2013) Luke C. Davies et al.   Nature Communications

Evidence of association between interferon regulatory factor 5 gene polymorphisms and asthma

(2012) Chuan Wang et al.   GENE

A two-marker haplotype in the IRF5 gene is associated with inflammatory bowel disease in a North American cohort

(2012) G Gathungu et al.   GENES AND IMMUNITY

Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages

(2012) Emmanuel L Gautier et al.   NATURE IMMUNOLOGY

Activation of Interferon Regulatory Factor 5 by Site Specific Phosphorylation

(2012) Hui-Chen Chang Foreman et al.   PLoS One

Interferon regulatory factor 5 activation in monocytes of systemic lupus erythematosus patients is triggered by circulating autoantigens independent of type I interferons

(2011) Rivka C. Stone et al.   ARTHRITIS AND RHEUMATISM

IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses

(2011) Thomas Krausgruber et al.   NATURE IMMUNOLOGY

Local Macrophage Proliferation, Rather than Recruitment from the Blood, Is a Signature of TH2 Inflammation

(2011) S. J. Jenkins et al.   SCIENCE

Macrophages in Synovial Inflammation

(2011) Aisling Kennedy et al.   Frontiers in Immunology

The interferon regulatory factor 5 gene confers susceptibility to rheumatoid arthritis and influences its erosive phenotype

(2010) K. Dawidowicz et al.   ANNALS OF THE RHEUMATIC DISEASES

Alternative Activation of Macrophages: Mechanism and Functions

(2010) Siamon Gordon et al.   IMMUNITY

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

(2010) Eli A Stahl et al.   NATURE GENETICS

Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

(2010) Subhra K Biswas et al.   NATURE IMMUNOLOGY

Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment

(2010) K. Nistala et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IKKα negatively regulates IRF-5 function in a MyD88–TRAF6 pathway

(2009) Mumtaz Yaseen Balkhi et al.   CELLULAR SIGNALLING

Animal models of rheumatoid arthritis

(2009) Darren L. Asquith et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

GFP-p65 knock-in mice as a tool to study NF-κB dynamics in vivo

(2009) Rossana De Lorenzi et al.   GENESIS

Promotion of the local differentiation of murine Th17 cells by synovial macrophages during acute inflammatory arthritis

(2008) Paul J. Egan et al.   ARTHRITIS AND RHEUMATISM

Functional Regulation of MyD88-Activated Interferon Regulatory Factor 5 by K63-Linked Polyubiquitination

(2008) M. Y. Balkhi et al.   MOLECULAR AND CELLULAR BIOLOGY