Article
Geriatrics & Gerontology
Katherine M. Jones, Lydia Brown, Emma E. Houston, Christina Bryant
Summary: This study found that interference of HFNS in everyday life may predict increased anxiety during menopause for some women. However, self-compassion may have a stronger relationship with anxiety than menopausal symptoms.
Article
Oncology
Beverley de Valois, Teresa Young, Pam Thorpe, Tarsem Degun, Karen Corbishley
Summary: This study reports on the clinical outcomes of providing auricular acupuncture to breast cancer survivors to manage hot flushes and night sweats. The findings show a significant reduction in HFNS frequency and associated menopausal symptoms, indicating that NADA may be a safe and effective intervention for breast cancer survivors in daily clinical practice.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Geriatrics & Gerontology
Carolyn J. Crandall, Joseph C. Larson, Kristine E. Ensrud, Andrea Z. LaCroix, Katherine A. Guthrie, Susan D. Reed, Shalender Bhasin, Susan Diem
Summary: This study evaluated the relationship between serum hormone levels and menopausal symptom bother, finding that single measurements of E1, E2, or SHBG concentrations are not useful in distinguishing between women bothered by specific menopausal symptoms and those who are not.
Article
Endocrinology & Metabolism
Carmen Pingarron, Pilar de Lafuente, Antonio Maria Ierullo, Silvia Poyo Torcal, Carlos Javier Maroto Diaz, Santiago Palacios
Summary: The study found that after 3 months of treatment with ospemifene, the vaginal health index increased, while vaginal pH, dryness, and dyspareunia decreased significantly. There was also a significant improvement in sexual function and quality of life.
GYNECOLOGICAL ENDOCRINOLOGY
(2021)
Article
Multidisciplinary Sciences
Jerilynn C. Prior, Andrea Cameron, Michelle Fung, Christine L. Hitchcock, Patricia Janssen, Terry Lee, Joel Singer
Summary: This study examined the efficacy of progesterone in treating vasomotor symptoms (VMS) in perimenopausal women. The results showed that there was no significant difference in VMS scores between the group receiving progesterone and the placebo group.
SCIENTIFIC REPORTS
(2023)
Article
Polymer Science
Guglielmo Stabile, Giuseppe Ricci, Maria Sole Scalia, Francesco De Seta
Summary: An experimental model of dryness on vaginal mucosa was used to assess the efficacy of a new vaginal gel, Respecta(R) Hydragel. The gel demonstrated efficacy in regulating water flux and increasing hyaluronic acid expression, resulting in improved hydration and elasticity of the vaginal mucosa.
Article
Urology & Nephrology
Lee A. Richter, Oyomoare L. Osazuwa-Peters, Jonathan C. Routh, Victoria L. Handa
Summary: Cystectomy with a vaginal-sparing approach may lead to unique complications in females. This study aimed to estimate the incidence of vaginal complications after cystectomy and identify risk factors. The results showed that over 20% of women experienced complications, and more than a quarter of those diagnosed required intervention.
JOURNAL OF UROLOGY
(2022)
Article
Public, Environmental & Occupational Health
Nicolas Berreni, Jennifer Salerno, Thierry Chevalier, Sandrine Alonso, Pierre Mares
Summary: The study examined the effects of multipoint intra-mucosal injections of crosslinked hyaluronic acid (Desirial(R)) on VVA symptoms, vaginal health, and sexual function. The results demonstrated a significant stimulation of collagen formation, reduced VVA symptoms, improved patient satisfaction, and sexual function scores.
Article
Obstetrics & Gynecology
A. A. A. Ewies, I Ahmed, F. Al-Azzawi, J. Pitkin, P. Gupta, M. Persic, B. Sahu, A. Elgobashy, L. Barraclough, J. Woodman, J. Babrah, S. Bowden, D. Stocken, L. Billingham, S. Sundar, D. Rea
Summary: The study did not show a statistically significant difference in reducing Hot Flush Score over 12 weeks between folic acid and placebo groups in postmenopausal women. However, there was an increased benefit in the folic acid group regarding changes in total and emotional UQoL scores at week 8 compared with placebo.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2021)
Article
Nursing
Cherish Boxall, Deborah Fenlon, Carl May, Jacqui Nuttall, Myra S. Hunter
Summary: This paper reports the findings of a qualitative process evaluation that explored the effectiveness of breast care nurse-led group cognitive behavioural therapy (CBT) for women after breast cancer treatment. The study found that the BCN-led group CBT was beneficial for alleviating acute symptoms in patients, but there were barriers to its long-term implementation into routine care.
Article
Oncology
Stefano Salvatore, Rossella E. Nappi, Arianna Casiraghi, Alessandro F. Ruffolo, Rebecca Degliuomini, Marta Parma, Umberto Leone Roberti Maggiore, Stavros Athanasiou, Massimo Candiani
Summary: The pilot study aimed to evaluate the efficacy and safety of microablative fractional CO2 laser in treating VVA symptoms in women with a history of breast cancer. The results showed that laser treatment significantly improved VVA symptoms and overall quality of life in these patients.
CLINICAL BREAST CANCER
(2021)
Article
Clinical Neurology
Carlos Alberto Nigro, Ignacio Bledel, Eduardo Borsini
Summary: This study assessed the relationship between hypoxemia during polysomnography (PSG) and patient-reported night sweats (NS). The study found that night sweats were significantly and independently associated with a higher hypoxic burden in patients with obstructive sleep apnea (OSA).
SLEEP AND BREATHING
(2023)
Article
Medicine, Research & Experimental
Simon Crabb, Alannah Morgan, Myra S. S. Hunter, Evgenia Stefanopoulou, Gareth Griffiths, Alison Richardson, Deborah Fenlon, Louisa Fleure, James Raftery, Cherish Boxall, Sam Wilding, Jacqueline Nuttall, Zina Eminton, Emma Tilt, Alice O'Neill, Roger Bacon, Jonathan Martin
Summary: This study aims to assess the effectiveness of a guided self-help cognitive behavioural therapy (CBT) intervention, delivered by the existing NHS prostate cancer CNS team, in reducing the impact of hot flushes and night sweats (HFNS) in men undergoing androgen deprivation therapy (ADT). It will evaluate the intervention through a randomized controlled trial and explore the key influencers to its implementation through a process evaluation.
Article
Nutrition & Dietetics
Ria Kwon, Yoosoo Chang, Yejin Kim, Yoosun Cho, Hye Rin Choi, Ga-Young Lim, Jeonggyu Kang, Kye-Hyun Kim, Hoon Kim, Yun Soo Hong, Jihwan Park, Di Zhao, Sanjay Rampal, Juhee Cho, Eliseo Guallar, Hyun-Young Park, Seungho Ryu
Summary: The role of alcohol consumption in the risk of vasomotor symptoms among premenopausal women was examined. Greater alcohol consumption was associated with an increased risk of vasomotor symptoms. Refraining from alcohol consumption may help prevent these symptoms in premenopausal women.
Article
Nutrition & Dietetics
Lynnette Leidy Sievert, Taniya Sharmeen, Khurshida Begum, Shanthi Muttukrishna, Osul Chowdhury, Gillian R. Bentley
Summary: This study examined the relationship between diet and menopausal symptoms in Bangladeshi women living in Sylhet and London. The findings showed that increased consumption of phytoestrogens and lignans was associated with higher likelihood of hot flashes, while higher consumption of phytoestrogens, lignans, and isoflavones was associated with lower likelihood of vaginal dryness. Night sweats and trouble sleeping were not influenced by phytoestrogen intake.
Article
Endocrinology & Metabolism
Alexis C. Garduno, Andrea Z. LaCroix, Michael J. LaMonte, David W. Dunstan, Kelly R. Evenson, Guangxing Wang, Chongzhi Di, Benjamin T. Schumacher, John Bellettiere
Summary: This study found that older adults who took more steps per day had a lower risk of incident diabetes, and moderate to vigorous-intensity steps were most strongly associated with a lower diabetes hazard.
Article
Geriatrics & Gerontology
Mikael Anne Greenwood-Hickman, Rod Walker, John Bellettiere, Andrea Z. LaCroix, Boeun Kim, David Wing, KatieRose Richmire, Paul K. Crane, Eric B. Larson, Dori E. Rosenberg
Summary: Neighborhood walkability is associated with physical activity and sedentary behavior in older adults, but the associations may vary by gender and age.
JOURNAL OF AGING AND PHYSICAL ACTIVITY
(2022)
Article
Geriatrics & Gerontology
Qian Xiao, Joshua N. Sampson, Andrea Z. LaCroix, Aladdin H. Shadyab, Jamie M. Zeitzer, Sonia Ancoli-Israel, Kristin Yaffe, Katie Stone
Summary: Less stable and more variable rest-activity rhythms may serve as early biomarkers of cognitive impairment in older adults.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2022)
Article
Geriatrics & Gerontology
Carolyn J. Crandall, Joseph C. Larson, Kristine E. Ensrud, Andrea Z. LaCroix, Katherine A. Guthrie, Susan D. Reed, Shalender Bhasin, Susan Diem
Summary: This study evaluated the relationship between serum hormone levels and menopausal symptom bother, finding that single measurements of E1, E2, or SHBG concentrations are not useful in distinguishing between women bothered by specific menopausal symptoms and those who are not.
Article
Obstetrics & Gynecology
Kristine E. Ensrud, Joseph C. Larson, Katherine A. Guthrie, Carolyn J. Crandall, Andrea Z. LaCroix, Susan D. Reed, Shalender Bhasin, Caroline M. Mitchell, Hadine Joffe
Summary: This study found that low-dose oral estradiol treatment can significantly increase serum concentrations of E2 and E1 in perimenopausal and postmenopausal women, and these changes in concentration partially mediate the reduction of vasomotor symptom frequency.
MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY
(2022)
Article
Psychology, Clinical
Shubhabrata Mukherjee, Seo-Eun Choi, Michael L. Lee, Phoebe Scollard, Emily H. Trittschuh, Jesse Mez, Andrew J. Saykin, Laura E. Gibbons, R. Elizabeth Sanders, Andrew F. Zaman, Merilee A. Teylan, Walter A. Kukull, Lisa L. Barnes, David A. Bennett, Andrea Z. Lacroix, Eric B. Larson, Michael Cuccaro, Shannon Mercado, Logan Dumitrescu, Timothy J. Hohman, Paul K. Crane
Summary: This study aims to harmonize cognitive domain scores across multiple studies by cocalibrating data from different instruments. Through confirmatory factor analysis models, the study establishes a large item bank and derives scores for different cognitive domains. The systematic approach allows for the inclusion of additional studies and enables robust investigation of cognition in the context of aging and dementia.
Article
Medicine, General & Internal
Purva Jain, Alexandra M. Binder, Brian Chen, Humberto Parada, Linda C. Gallo, John Alcaraz, Steve Horvath, Parveen Bhatti, Eric A. Whitsel, Kristina Jordahl, Andrea A. Baccarelli, Lifang Hou, James D. Stewart, Yun Li, Jamie N. Justice, Andrea Z. LaCroix
Summary: This study investigated the association between epigenetic age acceleration (EAA), a biomarker associated with aging, and healthy longevity among older women. The findings suggest that EAA may be a valid biomarker associated with healthy longevity among older women and may be used for risk stratification and risk estimation of future functional and cognitive aging.
Article
Clinical Neurology
Steve Nguyen, Andrea Z. LaCroix, Kathleen M. Hayden, Chongzhi Di, Priya Palta, Marcia L. Stefanick, JoAnn E. Manson, Stephen R. Rapp, Michael J. LaMonte, John Bellettiere
Summary: Accelerometer measures of physical activity and sitting are associated with the risk of mild cognitive impairment and dementia, with at least moderate intensity physical activity and steps showing a lower risk for these conditions.
ALZHEIMERS & DEMENTIA
(2023)
Article
Oncology
Elizabeth Cespedes M. Feliciano, Sowmya Vasan, Juhua Luo, Alexandra M. Binder, Rowan T. Chlebowski, Charles Quesenberry, Hailey R. Banack, Bette J. Caan, Electra D. Paskett, Grant R. Williams, Ana Barac, Andrea Z. LaCroix, Ulrike Peters, Kerryn W. Reding, Kathy Pan, Aladdin H. Shadyab, Lihong Qi, Garnet L. Anderson
Summary: Patients with cancer experience acute declines in physical function, which may be due to cancer-related symptoms and cancer treatments. This study examined the long-term trajectories of physical function among older cancer survivors and cancer-free controls. The results showed that cancer survivors experienced accelerated declines in physical function after diagnosis, and their physical function remained below that of age-matched controls even years later.
Article
Psychology, Multidisciplinary
Rita H. Ryu, Britta Larsen, Andrea LaCroix, Steve Nguyen, Alex Ivan B. Posis, Benjamin T. Schumacher, Suzanne C. Danhauer, Hilary A. Tindle, John Bellettiere
Summary: Psychological well-being is associated with healthy aging in older women, and this study aims to examine how physical behavior relates to optimism and positive affect in a diverse sample of older women. The findings suggest that greater physical activity and less sedentary time are associated with higher levels of optimism and positive affect in older women, even after adjusting for age, race, ethnicity, social support, and chronic conditions.
JOURNAL OF HAPPINESS STUDIES
(2023)
Article
Oncology
Eric T. Hyde, Andrea Z. LaCroix, Kelly R. Evenson, Annie Green Howard, Blake Anuskiewicz, Chongzhi Di, John Bellettiere, Michael J. LaMonte, JoAnn E. Manson, Julie E. Buring, Eric J. Shiroma, I-Min Lee, Humberto Parada Jr
Summary: This study examined the association between accelerometer-measured physical activity and breast cancer risk. It found that higher levels of physical activity were associated with a lower risk of breast cancer, and this association varied by age and obesity, as well as BMI or physical function.
Article
Geriatrics & Gerontology
Alexander Ivan B. Posis, John Bellettiere, Rany M. Salem, Michael J. LaMonte, JoAnn E. Manson, Ramon Casanova, Andrea Z. LaCroix, Aladdin H. Shadyab
Summary: The aim of this study was to investigate the relationship between accelerometer-measured physical activity (PA) and sedentary time (ST) with mortality risk, considering a genetic risk score (GRS) for longevity. Among 5,446 women, aged 78.2 (SD: 6.6) years, 1,022 deaths occurred during the 33,350 person-years of follow-up. The findings revealed that higher levels of light and moderate to vigorous PA were associated with reduced mortality risk, regardless of GRS category. Conversely, higher sedentary time was linked to increased mortality risk, independent of GRS category. The interaction tests between PA and ST with GRS were not statistically significant.
JOURNAL OF AGING AND PHYSICAL ACTIVITY
(2023)
Article
Psychology, Clinical
Lisa Smith Kilpela, Victoria B. Marshall, Savannah C. Hooper, Carolyn Black Becker, Pamela K. Keel, Andrea Z. LaCroix, Nicolas Musi, Sara E. Espinoza
Summary: Emerging research suggests that binge eating is common among older adult women. This study aimed to understand the characteristics of older women (aged 60+ years) with objective binge episodes (OBE) in later-life, including age of onset, distress, and frequency of OBE. Clinical interviews were conducted with 71 participants, and it was found that 77.5% met the DSM-5 criteria for OBE (occurring at least once a week for at least three months), with different age onsets reported. Older women with OBE in later-life experienced distress related to aging, self-blame, loss of control, and cognitive fixation on satiation. These findings emphasize the need for research on interventions for this population.
Review
Psychology, Multidisciplinary
Yinxiang Wu, Dori E. Rosenberg, Mikael Anne Greenwood-Hickman, Susan M. McCurry, Cecile Proust-Lima, Jennifer C. Nelson, Paul K. Crane, Andrea Z. LaCroix, Eric B. Larson, Pamela A. Shaw
Summary: The 24-h activity cycle (24HAC) is a new paradigm that captures the interrelatedness of physical activity, sedentary behavior, and sleep in relation to health outcomes. This study compares three analytical approaches (ISM, CoDA, and LPA) to assess the association between 24HAC and cognitive function in older adults. The results suggest that less sedentary behavior and more physical activity do not necessarily lead to better cognitive function.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Obstetrics & Gynecology
Erin E. McCoy, Ronit Katz, Diana K. N. Louden, Emiko Oshima, Amy Murtha, Cynthia Gyamfi-Bannerman, Nanette Santoro, Elizabeth A. Howell, Lisa Halvorson, Susan D. Reed, Barbara A. Goff
Summary: This study evaluated the scholarly productivity of individuals supported by the Eunice Kennedy Shriver National Institute of Child Health and Human Development Women's Reproductive Health Research K12 career development award. The findings suggest that this award is advantageous for the career development of obstetrician-gynecologists, particularly female surgeons, and may help address gender disparities in National Institutes of Health funding.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2023)
Article
Geriatrics & Gerontology
Lum Kastrati, Dion Groothof, Hugo G. Quezada-Pinedo, Hamidreza Raeisi-Dehkordi, Lia Bally, Martin H. De Borst, Stephan J. L. Bakker, Pedro-Marques Vidal, Michele F. Eisenga, Taulant Muka
Summary: The study aimed to examine the association between iron biomarkers and menopausal status and assess whether these biomarkers can help differentiate menopausal status beyond age. The results showed that iron biomarkers were significantly associated with menopausal status in both cohorts and modestly improved a model with age alone for differentiating menopause status.
Article
Geriatrics & Gerontology
Osvaldo P. Almeida, Christopher Etherton-Beer, Frank Sanfilippo, David B. Preen, Amy Page
Summary: The use of antineoplastic medications has been found to be associated with a decreased risk of dementia, which may contribute to the development of novel approaches for dementia prevention.
Article
Geriatrics & Gerontology
Bamini Gopinath, Diana Tang, George Burlutsky, Paul Mitchell
Summary: This study used a cohort of community-dwelling adults to establish the 10-year incidence and predictors of dizziness/vertigo, and its impacts on health-related quality of life. The results showed that age and presence of migraine were significant predictors of incident dizziness/vertigo, and dizziness/vertigo was associated with a significant decrease in quality of life.
Article
Geriatrics & Gerontology
Yuto Kiuchi, Kota Tsutsumimoto, Takehiko Doi, Satoshi Kurita, Kazuhei Nishimoto, Hyuma Makizako, Hiroyuki Shimada
Summary: This study found that high dietary diversity is associated with a lower risk of incident disability among sarcopenic Japanese older adults.
Article
Geriatrics & Gerontology
C. . Tamer Erel, Ipek Betul Ozcivit Erkan, Neslihan Gokmen Inan, Kubra Hamzaoglu Canbolat, Sena Alkan, Dildar Konukoglu, Yalim Dikmen
Summary: This study aimed to compare the clinical course and outcomes of Covid-19 between premenopausal and postmenopausal women, and investigate the factors that influence disease severity. The results showed that premenopausal women had a more favorable prognosis, and age, postmenopausal status, and serum levels of dehydroepiandrosterone sulfate were important predictors of the severity of Covid-19 in women.
Article
Geriatrics & Gerontology
Kazuhei Nishimoto, Kota Tsutsumimoto, Takehiko Doi, Satoshi Kurita, Yuto Kiuchi, Hiroyuki Shimada
Summary: The combination of urinary incontinence and low life-space activity/mobility is associated with an increased risk of incident disability among older adults, while having urinary incontinence but high life-space activity/mobility is not associated with an increased risk of incident disability.
Review
Geriatrics & Gerontology
Nikolaos Evangelinakis, Eleni V. Geladari, Charalampia V. Geladari, Adamantia Kontogeorgi, Georgios-Konstantinos Papaioannou, Melpomeni Peppa, Sophia Kalantaridou
Summary: Premature ovarian insufficiency and ovarian aging are complex conditions that affect women's reproductive health and overall well-being. This review explores the influence of environmental factors, including endocrine-disrupting chemicals and lifestyle choices, on the development and progression of these conditions. Understanding the impact of environmental factors is important for public and clinical health contexts.
Article
Geriatrics & Gerontology
Adela Castello, Miguel Rodriguez-Barranco, Virginia Lope, Marcela Guevara, Sandra Colorado-Yohar, Ane Dorronsoro, Jose Ramon Quiros, Carlota Castro-Espin, Carmen Sayon-Orea, Carmen Santiuste, Pilar Amiano, Cristina Lasheras, Maria-Jose Sanchez, Marina Pollan
Summary: The study found that the intake of foods such as high-fat dairy products, red and processed meats, refined grains, sweets, caloric drinks, convenience food and sauces might be associated with a higher risk of breast cancer.
