☆ 4.6 Article

Extracellular matrix of adipogenically differentiated mesenchymal stem cells reveals a network of collagen filaments, mostly interwoven by hexagonal structural units

MATRIX BIOLOGY (2013)

获取全文
添加到收藏夹

期刊

MATRIX BIOLOGY
卷 32, 期 7-8, 页码 452-465

出版社

ELSEVIER SCIENCE BV
DOI: 10.1016/j.matbio.2013.07.001

关键词

ECM; Integrins; Cadherins; Selectins; Lipid droplets; Matrix signaling

类别

Biochemistry & Molecular Biology Cell Biology

资金

  1. Investment Bank Berlin (IBB)
  2. European Regional Development Fund [10147246]
  3. Berlin-Brandenburg Center for Regenerative Therapies
  4. Federal Ministry of Education and Research, Germany [0315848A]

向作者/读者索取更多资源

Protocol

社区支持

Reagent

社区支持

Extracellular matrix (ECM) is the non-cellular component of tissues, which not only provides biological shelter but also takes part in the cellular decisions for diverse functions. Every tissue has an ECM with unique composition and topology that governs the process of determination, differentiation, proliferation, migration and regeneration of cells. Little is known about the structural organization of matrix especially of MSC-derived adipogenic ECM. Here, we particularly focus on the composition and architecture of the fat ECM to understand the cellular behavior on functional bases. Thus, mesenchymal stem cells (MSC) were adipogenically differentiated, then, were transferred to adipogenic propagation medium, whereas they started the release of lipid droplets leaving bare network of ECM. Microarray analysis was performed, to indentify the molecular machinery of matrix. Adipogenesis was verified by Oil Red 0 staining of lipid droplets and by qPCR of adipogenic marker genes PPARG and FABP4. Antibody staining demonstrated the presence of collagen type I, II and IV filaments, while alkaline phosphatase activity verified the ossified nature of these filaments. In the adipogenic matrix, the hexagonal structures were abundant followed by octagonal structures, whereas they interwoven in a crisscross manner. Regarding molecular machinery of adipogenic ECM, the bioinformatics analysis revealed the upregulated expression of COL4A1, ITGA7, ITGA7, SDC2, ICAM3, ADAMTS9, TIMP4, GPC1, GPC4 and downregulated expression of COL14A1, ADAMTS5, TIMP2, TIMP3, BGN, LAMA3, ITGA2, ITGA4, ITGB1, ITGB8, CLDN11. Moreover, genes associated with integrins, glycoproteins, laminins, fibronectins, cadherins, selectins and linked signaling pathways were found. Knowledge of the interactive-language between cells and matrix could be beneficial for the artificial designing of biomaterials and bioscaffolds. (C) 2013 Elsevier B.V. All rights reserved.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.6
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

Article Chemistry, Physical

Modified gold and polymeric gold nanostructures: Toxicology and biomedical applications

Muneeb Ullah, Abdul Wahab, Dilfaraz Khan, Sumbul Saeed, Shahid Ullah Khan, Naimat Ullah, Tawfik A. Saleh

Summary: The functionalization of gold nanoparticles has been extensively studied and applied in various fields due to their unique properties. This review critically discusses different methods for synthesizing Au/NPs and highlights their potential applications in theranostics, antibacterial mechanisms, in vitro and in vivo cytotoxicity, as well as drug delivery systems with a focus on cancer therapy. Au/NPs are seen as a novel and powerful tool in therapies, drug delivery systems, and toxicology research.

COLLOID AND INTERFACE SCIENCE COMMUNICATIONS (2021)

添加到收藏夹
Review Environmental Sciences

Coronavirus and its terrifying inning around the globe: The pharmaceutical cares at the main frontline

Muneeb Ullah, Abdul Wahab, Sumbul Saeed, Shahid Ullah Khan, Haider Ali, Shah Humayun, Banzeer Ahsan Abbasi, Shah Saud, Khalid Naveed, Sher Aslam Khan, Shah Fahad

Summary: The novel coronavirus, officially declared a global pandemic by WHO, has a serious impact on human life.

CHEMOSPHERE (2021)

添加到收藏夹
Review Cell Biology

Methodologies to Isolate and Purify Clinical Grade Extracellular Vesicles for Medical Applications

Asma Akbar, Farzaneh Malekian, Neda Baghban, Sai Priyanka Kodam, Mujib Ullah

Summary: This study discusses the sources of extracellular vesicles and emphasizes the importance of standardization in isolation and purification methods. It suggests that standardization can lead to more extensive clinical applications with less concerns about side effects and better understanding of therapeutic mechanisms.

CELLS (2022)

添加到收藏夹
Review Neurosciences

Exosome engineering for efficient and targeted drug delivery: Current status and future perspective

Farzaneh Malekian, Alireza Shamsian, Sai Priyanka Kodam, Mujib Ullah

Summary: Exosomes are membrane-bound vesicles that play an important role in drug delivery. However, limitations in isolation and delivery procedures restrict their clinical use. Bioengineering of exosomes can enhance their drug delivery potential.

JOURNAL OF PHYSIOLOGY-LONDON (2022)

添加到收藏夹
Retraction Chemistry, Multidisciplinary

撤稿声明: Controlled Nutrient Delivery to Pancreatic Islets Using Polydopamine-Coated Mesoporous Silica Nanoparticles? (Retraction of Vol 20, Pg 7220, 2022)

Mehdi Razavi, Rosita Primavera, Bhavesh Kevadiya, Jing Wang, Mujib Ullah, Peter Buchwald, Avnesh S. Thakor

NANO LETTERS (2022)

添加到收藏夹
Review Cell Biology

Different Sourced Extracellular Vesicles and Their Potential Applications in Clinical Treatments

Leila Bahmani, Mujib Ullah

Summary: Extracellular vesicles (EVs) are promising biotherapeutic agents and drug delivery vehicles in human medicine, with the ability to bypass membranous barriers and deliver bioactive components. Different EVs derived from various cell sources have been shown to have therapeutic effects on different human disorders. However, there are still challenges hindering the clinical translation of EV therapies.

CELLS (2022)

添加到收藏夹
Review Cardiac & Cardiovascular Systems

Stent as a Novel Technology for Coronary Artery Disease and Their Clinical Manifestation

Muneeb Ullah, Abdul Wahab, Shahid Ullah Khan, Umber Zaman, Khalil Ur Rehman, Shah Hamayun, Muhammad Naeem, Haider Ali, Tayyaba Riaz, Sumbul Saeed, Amnah Mohammed Alsuhaibani, Moamen S. Refat

Summary: Coronary artery disease (CAD) is a cardiovascular disease characterized by narrowed and hardened blood vessels, resulting in insufficient blood supply to the heart. The prevalence of CAD is increasing globally, causing higher mortality and morbidity rates and negatively impacting quality of life. It is also a significant burden on healthcare systems. Risk factors such as high cholesterol, smoking, diabetes, obesity, and hypertension contribute to the development of CAD. Diagnosis and management involve medication and stent technology, which has proven to be beneficial but also comes with potential complications.

CURRENT PROBLEMS IN CARDIOLOGY (2023)

添加到收藏夹
Letter Neurosciences

The future of exosomes bioengineering in precision medicine

Mujib Ullah

JOURNAL OF PHYSIOLOGY-LONDON (2022)

添加到收藏夹
Article Mathematical & Computational Biology

A computational classification method of breast cancer images using the VGGNet model

Abdullah Khan, Asfandyar Khan, Muneeb Ullah, Muhammad Mansoor Alam, Javed Iqbal Bangash, Mazliham Mohd Suud

Summary: Cancer, especially breast cancer, is a prevalent and challenging disease to detect and classify. This study proposes a new convolutional neural network (CNN) model based on VGGNet for breast cancer diagnosis and classification. By reducing the number of layers, the VGGNet-12 model overcomes the problem of overfitting and achieves better performance compared to other models.

FRONTIERS IN COMPUTATIONAL NEUROSCIENCE (2022)

添加到收藏夹
Review Chemistry, Inorganic & Nuclear

The potential of marine-based gold nanomaterials in cancer therapy: a mini-review

Neda Baghban, Arezoo Khoradmehr, Iraj Nabipour, Amin Tamadon, Mujib Ullah

Summary: This article reviews the application of marine-based gold nanoparticles in the diagnosis and treatment of cancer, highlighting their potential in detecting and imaging cancer cells, drug delivery systems, and cancer treatment. However, limited research has been conducted on the use of gold nanoparticles in marine natural products for cancer therapy, with most studies focusing on their role as drug delivery systems.

GOLD BULLETIN (2022)

添加到收藏夹
Review Oncology

Diagnostic and Therapeutic Potential of Extracellular Vesicles

Sai Priyanka Kodam, Mujib Ullah

Summary: Extracellular vesicles (EVs) are nanovesicles released by cells in the body, stable in circulation, with low immunogenicity, and act as carriers for biologically active molecules. They play a vital role in cellular communication, protecting cargo from degradation, and have potential for targeted drug delivery. Tracking EVs in systemic circulation can revolutionize their use as diagnostic tools, despite limitations in isolation and storage.

TECHNOLOGY IN CANCER RESEARCH & TREATMENT (2021)

添加到收藏夹
Review Surgery

BJS commission on surgery and perioperative care post-COVID-19

E. Abahuje, A. Abbas, M. Abd El Aziz Abd El Maksoud, A. Abdelhady, S. Abdelhamid, H. Abdelkarem Ahmed Faraj, B. Abdelqader, T. Abdelrahman, H. Abdou, A. Abdullah, M. Abedua Harrison, E. Abem Owusu, A. Aboalazayem, R. Aboulhosn, S. AbuOda, A. Abubakar, A. Abutaka, D. Acevedo Fontalvo, S. Acuna, A. Adefemi, S. Adegbola, T. Adenuga, A. Adeyeye, A. Adil Hilmi, A. Adisa, K. Aditya, T. Adjeso, R. Aftab, A. Afzal, V Aggarwal, A. Aggarwal, R. Aguilera, M-L Aguilera-Arevalo, E. J. Aguirre Salamanca, I Aguirre-Allende, D. Ahari, H. Ahmad, F. Ahmad Rauf, A. Ahmad Zartasht Khan, S. Ahmed, N. Ahmed Fieturi, S. Ahmed Mohamed, Z. Ahmed-Bakhsh, M. Ahsan Javed, L. Akano, A. Akbar, M. Akhbari, P. Akhmedov, G. Aksit, Y. Akula, A. S. Alagaratnam, S. Al Majid, O. Al Mukhtar, H. Al Omran, N. Al-Asali, M. Al-Azzawi, R. Al-Habsi, H. Al-Iraqi, H. Al-Naggar, E. Alameer, H. Albirnawi, D. Alderson, F. Aldulaijan, R. Alejandro Miranda Ojeda, A. AlHasan, S. Ali, A. Ali, M. Ali Khan, Y. Alimova, F. Aljanadi, R. Aljubure, N. Allopi, H. Almedbal, M. Almubarak, Z. Alqaidoom, N. Alselaim, M. Alshaar, R. Alshammari, K. Altaf, B. Altunpak, L. A. Alvarez Lozada, E. Amal Nahal, A. Amer, K. Amin, U. Aminu, N. Amisi Numbi, T. Amjad, R. Amoah, Y. An, N-A Anastasopoulos, J. Andres Urrutia, F. Angarita, K-L Angarita, M. Angel Freiria Eiras, A. Antypas, M. A. Anwar, H. Anwar, T. O. Apampa, K. Apostolou, C. Aquina, R. Arachchige Adithi Himika Randeni, O. Arez, A. A. Arezzo, P. Armonis, S. Arshad, M. Arshad Salman, A. Arshid, P. C. Arteaga Asensio, T. Arthur, A. Arumuga Jothi, F. Aryo Damara, L. Asensio Gomez, J. Ashcroft, S. Ashraf, A. Asif, M. Atif, M. Attaullah Khan, N. Avellaneda, S. Awad, M. Awadh, A. Axiaq, A. Ayad Mohammed Shuwayyah, D. Ayalew, E. Aytac, F. Azam, J. Azevedo, B. Azhar, J. Aziz, A. Aziz, A. Azzam, A. Baba Ndajiwo, M. Baig, D. Baker, F. Bakko, R. Balachandran, G. Balachandran, J. Balagizi Mudekereza, E. Balai, B. Balci, A. Balduzzi, A. Balhareth, S. Bandyopadhyay, S. Bandyopadhyay, D. Banerjee, D. BangaloreMahalinga, B. Bankhead-Kendall, N. D. A. Bankole, V Banwell, F. Baris Bengur, B. Baris Ozmen, M. Barnard, R. Barnett, J. A. Barreras Espinoza, A. Barrios, G. Bass, M. Bass, A. Bausys, A. Bavikatte, J. Bayram, M. Belousov, A. G. Berardi, A. Beamish, C. Beattie, F. Belia, V Bellato, S. Bellikatti, S. Benjamens, C. Benlice, S. Bennedsgaard, S. Bennett, Z. Bentounsi, A. G. Berardi, H. Bergenfeldt, A. Bergenfelz, M. Besselink, G. Bhandoria, E. Bhangu, M. Bhatia, M. T. Bhatti, Z. Bilgili, G. Bislenghi, C. Bisset, S. Biswas, J. Blake, R. Blanco, L. Boccalatte, R. Boden, C. Bojanic, M. Boland, P. Boland, E. Bollen, E-A Bonci, L. Boni, A. Booth, R. Booth, A. Borakati, G. E. Borunda Escudero, S. J. Bosco, P. Botelho de Alencar Ferreira Cruz, K. Bouchagier, A. Bouhuwaish, M. Boutros, K. Boyce, C. Boyle, L. Bradshaw, A. Brandl, A. Brar, G. Brat, H. Brenkman, C. Brennan, C. Brines, A. Brookmyre, C. Brosnan, L. Brouwers, A. Brown, L. Brown, C. Brown, C. Brown, J. Brown, V Bs, M. Buksh, M. Bunani Emmanuel, D. Burbano, A. Burelli, A. Burke, J. Burke, N. Burlov, A. Burns, O. Burton, A. Butt, B. Buzra Ozkan, L. Cabrera Silva, E. Y. Caicedo, T. Calderbank, W. Cambridge, G. Campelo, O. Can Tatar, F. Carbone, F. Carrano, D. Casallas, D. Casanova Portoles, F. Casciani, I Cassimjee, O. A. Castaneda Ramirez, V Catalan, J. Caviedes, L. Cayetano, M. Ceresoli, M. Chan, V Chan, P. Chandrasinghe, S. Chapman, A. Chaturvedi, D. Chaudhry, H. Chaudry, H. W. Chen, A. Cheng, M. Chernykh, A. M. Cherrie, I Cheruiyot, J. Cheung, C. Chia, J. Chica, N. Chinai, A. Chirwa, J. Chiwaligo, A. Choi, J. Choi, M. R. Chowdhury, E. Christopher, N. Christou, T. Chu, D. Chua, H. W. Chua, C. Chung, A. Cihat Yildirim, M. Cillo, S. Cioffi, H. Claireaux, S. Clermonts, R. Clifford, M. Climent, A. Clynch, R-J Coelen, E. Colas-Ruiz, A. Collar, M. Collard, K. C. Conlon, T. Connelly, K. Connor, J. A. Cook, T. Correia de Sa, T. Costa, D. Couch, S. Cowper, B. Creavin, B. Crook, A. Curell, R. D'alessio, J. Dale, J. Damgaard Eriksen, I. Dario Martin Gonzalez, A. Darwish, M. Das, R. Das, K. Das, R. Dave, S. O. David, T. Davies, C. Davis, S. Davison, V Davletshina, A. Dawidziuk, A. Dawson, M. de AndresCrespo, H. de Berker, P. de Dieu Ngo, E. Dekker, R. de la Caridad Espinosa Luis, B. de Lacy, N. Demartines, A. de Montserrat Medina Sifuentes, S. De Silva, C. del Rio, V Delaune, A. Dell, S. Demirli Atici, M. Deniz Tepe, M. Derebey, G. Desai, M. Desai, S. Devarakonda, N. Deveras, G. Di Franco, M. Di Martino, F. Di Marzo, A. Diaz, G. Diaz del Gobbo, C. Diaz-Castrillon, L. Dick, K. Dickinson, E. Diego, I Dimasi, A. Ding, S. Dingemans, L. Dixon, B. Dixon, W. Doherty, D. Dooreemeah, C. Donohue, M. Dornseifer, F. Dossa, W. Dossou, T. Drake, I Drami, G. Drevin, M. C. du Plessis, N. Dudi-Venkata, R. Dudley, S. Duffy, D. Duklas, B-D Dumbrava, F. Duygu Avlar, A. Dworzynska, W. Ebrahim, A. Ebrahim, E. Efren Lozada Hernandez, N. Ehigie, M. ElBoghdady, C. El Hasnaoui, M. El Sheikh, A. El-Hussuna, O. Eldurssi, H. Elfeki, M. Elhadi, M. Elhassan, A. Elhissi, B. Elliot, C. Elsenbroek, B. Elsolh, N. Elson, H. Eltyeb, H. Emerson, S. H. Emile, G. Endalle, W. English, C. Ercisli, G. Espinosa, M. Essam Abdelraheem, H. Essangri, P. Etienne, M. D. Evans, T. Evans, C. Ezeme, F. Ezzahraa, T. Fadalla, J. Fagan, M. Fahmy, C. Fairfield, O. Falade, S. Famularo, F. Faqar-Uz-Zaman, Y. Farid, A. Farooq, H. Farooq, F. Farooqui, B. Farquharson, A. Faruqi, R. Faulder, M. Faut, K. Fechner, T. Feenstra, M. Fehervari, L. Fernandez, J. Fernandez Alberti, L. Ferrario, D. Field, L. Fiore, S. Fingerhut, S. Finlayson, N. Fleming, C. Fleming, E. Florial, M. Fok, D. Fokin, M. Foley, M. P. Forero, T. Forgan, M. Fornasiero, H. Fowler, G. Fowler, E. Franchi, L. Franklin, P. Fruhling, G. FuentesNavarrette, A. Fulop, M. Furtado, T. Gaarder, N. Galbraith, I. T. K. Gallagher, G. Gallo, T. Gana, E. Gaskin, M. Gasparini, R. G. Gatan, E. Geary, K. Gelaye Wudineh, G. Gemenetzis, M. Georgi, H. Ghalige, W. Ghareeb, T. Ghatwary Tantawy, C. Ghomsi, A. Ghuman, P. Giannakis, F. Giron, K. Gjengedal, E. Gkotsis, J. Glasbey, J. Glasbey, S. Godahewa, D. Godula, P. Goffredo, S. Goh, M. Golriz, L. Gomez, D. Gomez Gomez, R. Gonzalez, D. Gonzalez, E. Gonzalez Gutierrez, D. Gopar, L. Gordini, A. Gori, N. Gousy, R. Gowda, M. Gowda, J. Gqada, M. Grechenig, J. Greer, L. Gregorio, A. Grigorova, H. Grimes, V Groot, R. C. Grossman, R. Gruber, A. Gruter, R. Guest, R. Gujjuri, E. Gulcek, B. Gulcu, K. Gull, M. Gulmez, V Gupta, A. Gutlic, T. Guven, T. Gwatirisa, G. Gwini, P. Gwodog, S. Gysling, M. Habib, A. B. Hafeez Bhatti, J. Hallesmith, S. Halloran, M. Hamza Sadiq, C. Haney, N. Hanna, L. Hanna, M. Hannington, J. Harbjerg, D. Haribaskaran, N. Harran, B. Harrington, E. Harrison, R. Hasan, S. Hashmi, M. Hassan, M. Hassan, A. Hassan, L. Haverkamp, S. Hazen, B. Heer, J. Heil, J. Helliwell, N. Henriksen, D. Henshall, M. Hermanson, S. Hermena, D. Hettiarachchi, C. Hextall, M. Hidalgo, H. Hidayat, A. Hider, P. Higgins, R. Hinchliffe, D. Hirani, D. Hirpara, I Hisham, M. Hite, S. M. Hoh, C. Holmberg, F. Holst, A. Hossam, A. HossamElfallal, P. Howard, E. Huaman, Y. Huang, L. Huang, D. Huang, T. Huber, J. Hugh, J. Hughes, F. Huttner, R. Huynh, A. Hylands, J. Iannuzzi, B. Ielpo, A. Iftikhar Talib, J. Ignacio, P. Ignatavicius, S. Ike, C. Ikwu, M. Inama, A. Ing, A. Ingels, A. Isik, N. Islam, I. J. Ives, A. J. M. S. AlHasan, C. J. Perez Rivera, T. Jaffer, O. Jagiella-Lodise, M. Jain, M. Jain, K. Jain, M. Jakubauskas, M. Jalal, H. James, Y. Jang, B. Janssen, H. Jansson, H. Javanmard, S. Javed, U. Jayarajah, I Jayasuriya, J. Je, Z. Jessop, E. Jia Lin Tang, H. Jiang, Y. Jiayan, T. Jih Huei, R. Jimenez-Rodriguez, D. Joh, A. Johnson, N. Jones, C. Jones, C. Jordan, M. Jose Pizarro, C. Jose Salazar J. Joseph, C. Justiniano, T. Kabir, M. Kadhum, C. Kalfountzos, E. Kalogiannaki, K. Kalyanasundaram, S. Kamarajah, M. Kamil Quraishi, Y. Kanemitsu, A. Kapila, V Kapila, G. Karagiannidis, M. Kashif, S. Kathiravelupillai, A. Kathiravelupillai, E. Katsogridakis, K. Kaur, H. Kaur SekhonInderjit Singh, N. Kausur, M. Kawka, G. Keehan, S. Kehlet Watt, M. Kelly, M. E. Kelly, I. Kelvin Egbuchulem, G. Kembuan, E. Khajeh, A. Khaled Elfaitur, M. F. Khan, S. Khan, M. Khan, D. Khan, H. Khan, H. Khatkar, E. Khatkov, R. Khaw, B. Kim, K. Kishore Siddiraju, D. Kitua, S. Kmezic, S. Knight, S. Knight, T. Koeter, A. Koh, F. Koh Hong Xiang, T. Kojo Anyomih, A. I. N. Kok, R. Kokelaar, I Koliarakis, S. Kolli, J. Kong, J. Kong, D. Konig, D. Koshy, P. Kotze, A. Kourdouli, M. Kowal, A. Kraima, F. Kramer, M. Kryzauskas, I Kuchynskyi, C. Kuemmerli, S. Kuiper, S. Kumar, A. Kumar, A. Kumar, L. Kumar, H. Kumar, N. Kumar, S. Kumar, S. Kumar Bandyopadhyay, P. Kumar Garg, S. Kumar Venkatappa, J. Kung, S. Kural, A. Kushairi, E. Kuuzie, M. Kvietkauskas, I Kwek, J. La, L. Lai, S. Lakpriya, K. Lam, M. Lami, I Lansdorp-Vogelaar, P. Lapolla, H. Larsen, J. Latif, U. Laudari, A. Laurnezi, A. Lawal, S. Lawday, H. Lederhuber, A. Lednev, R. Lee, R. Lee, M. E. VanLeerdam, G. Lefevbre, M. Lesmus, F. A. Leyva Moraga, E. LeyvaMoraga, F. Leyva Moraga, H. L. Li, A. Li, Z. Li, E. Licardie, A. Light, A. L. Lightner, A. Lin, E. Lincango, F. Litta, H. Liu, B. Lofthouse, M. A. Londono, R. Lopes, R. Lopes de Freitas, L. Lopez, A. Lopez, J. Lopez-Gomez, G. Lopez-Pena, R. Lowe, D. Lowe, M. Lowey, G. Loy, V Lozanovski, J. Luzon, P. Lynn, T. Maccabe, A. Machielsen, L. Maggino, K. Mahawar, D. Mahmood, M. Mahmoud, K. Mahtani, I Maitra, S. Maji, I Majiet, L. Mal, J. Malherbe, K. Malhotra, P. Malkomes, E. Man, A. Manan Sheikh, S. Manjunath, R. Manzano Nunez, S. Manzoor, R. Maqsood, G. Marchegiani, F. Marchegiani, A. Marin, I Marks, I Marks, E. Marson, A. Martensen, D. Martin, B. Martin-Perez, P. Martinez, P. Marwaha, C. Mashauri, R. Masri, L. Masud, S. Masudi, G. Mateu Calabuig, S. Math, A. Matrachisia, J. Mayol, D. Mazingi, A. Mazzotta, J. McAlinden, G. McCabe, L. McColm, H. McElvaney, K. McGivern, J. McGovern, E. McGuinness, N. McInerney, S. Mckay, C. McKee, M. McKenna, N. McKenna, K. McLean, S. Mediratta, Y. Medkova, O. Medzhidov, A. Mehraj, M. Mekhael, O. Mekinde, C. Mellenthin, A. Melucci, K. Mentor, J. Merchant, H. Messias, M. Messeha, C. Meza, P. Mhango, M. Miladinov, M. Milagros Niquen Jimenez, P. Miller, E. Mills, A. Milton, O. A. Minayeva, Z. MinHua Zheng, H. Mischlinger, B. Mockli, R. Modi, H. M. Mohamed, M. Mohamed, T. Mohamed Abulghasm, S. A. Mohammad, T. O. Mohammed, A. Mohammed, H. Mohan, M. Mohan, I Moin, V Mok, G. Molina, J. Moloney, J. Moneim, M. Monfort Mira, M. Montouri, M. Moossdorff, I Mora-Guzman, B. Moran, R. A. R. Moran, S. Moreno-Ordaz, R. Morgan, R. Morley, D. Moro-Valdezate, S. Moros, J-L Moss, A. Morven, D. Morton, A. Moynihan, N. Muduli, N. Mugla, W. Mugla, P. Muller, G. Mun, R. Mundhada, I Munir, F. Munoz, E. Munoz, A. Munoz, D. C. Munoz Balderas, E. Murgitroyd, V Murray, S. Murthy, W. Mushiwokufa, H. Mustafa, B. Mustakimov, P. Mutambanengwe, P. Myint, S. Nadkarni, P. A. Naess, S. Nahar, P. Naidoo, R. Nam, S. Nandhra, N. Nanjappa, V Narasimhan, W. Nardi, M. Nasir, M. Nasir, A. Naughton, D. Naumann, S. Navarro, M. NawaazKarimbocus, A. Nazir, S. Ndereya, A. Ndong, I Negoi, D. Nel, D. Nelson, S. Nepal, T. Nugent, D. Nepogodiev, J. Neufeld, J. Ng, D. Ng, C. E. Ng, J. Ng, S. Ngaserin, L. Ngu, E. Ngwenya, R. N. Fhearaigh, T-K Nikolousakis, M. Ninkovic, G. Nita, C. Nitschke, E. Noren, T. Noton, A. Novikova, Z. Nowinka, T. Nugent, T. Nyakunengwa, A. Nyalundja, I Nzenwa, H. O. Kristensen, C. O'Brien, L. O'Brien, S. O'Brien, J. O'Reilly, S. O'Rourke, M. O'Sullivan, M. O'Dwyer, L. Ochieng, E. Oderoha, K. E. Oh, L. Ohlberger, M. O. Lcum, A. Olkina, M. Omkumar, B. Omnitel, D. Oncel Yakar, K. Ong, L. Ong Wei Lin, R. Ooi, S. Ooi, A. Oomman, D. Oon Tyjet, S. Opiyo, J. J. Oscullo Yepez, N. Osei-kuffour, T. Osunronbi, S. Oussama Kacimi, S. Ovaere, A. Ozair, F. Pachler, S. Pai Oo, S. Paiella, L. Panaiotti, N. Panda, S. Pandarinath, D. Pandey, S. Pandrowala, F. Papa Mamadou, M. Paranathala, J. Park, C. Parmar, A. Parvez, L. Pasovic, A. Pasquer, N. Pasumarthy, F. Pata, T. Patel, P. Patel, N. Patel, M. Patel, P. Patel, N. Patron Uriburu, R. Patrone, A. Paul, O. M. Pavan Kumar, A. Pavithran, M. Pedraza Ciro, G. Pellino, A. Peloso, M. T. PenaGallardo, A. Pena Velazquez, J. Perea, L. E. Perez-Sanchez, T. Perra, G. Perrotta, P. Petersson, G. Petra, N. Petrucciani, C. Pickin, V Pino, E. Pinotti, F. Pinto, P. Plum, F. Podesta, T. Pollini, M. Pompeu Sa, F. Ponce Leon, H. S. Ponniah, X. Ponte de Sousa, J. Ponton, A. Pontula, M. Popa, A. L. Portilla, F. Posner, S. Post, A. Potolicchio, S. Pouwels, A. Povo, P. Prasad, S. Preciado, R. Preece, D. Proud, J. A. Pulido Segura, N. Puliyath, M. Qui, A. S. Quimbaya Rodriguez, W. Raby-Smith, A. Racovita, A. Rad, R. Radwan, M. Rafaih Iqbal, A. Rafik, B. Raguan, M. Rahi, J-L Rahiri, J. Rahme, L. Rai, A. Raj, A. Raj Saksena, M. Raja, J. Ramirez, J. Ramzi, J. Ranstam, C. Rao, A. Rashid, B. Ratnayake, K. Rattanasirivilai, K. Raubenheimer, N. Ravikumar, S. Ravn, N. Razoz, W. Rea, A. Regan, M. Rela, A. Remme, C. E. Rey Chaves, A. Reyes, A. Riad, D. Rice, K. Rios Quintana, A. Ritter, M. Roalso, D. Robinson, J. Rodriguez, M. C. Rodriguez, A. Rogers, J. Rohila, D. Romanyuc, I Romic, M. Rommaneh, G. Rompianesi, F. Rosa, F. Roscio, A. Rose, T. Rotimi, H. Ruiz, J. Ruiz Yucuma, M. Ruslan, M. Rutegard, E. Ryan Harper, A. Ryckx, D. Rydbeck, E. Sa-Marta, I Sadien, D. Safari Nteranya, K. Sagoo, S. Sakata, E. Saladino, A. Saleem, S. Saleem, M. Salehi, S. Salih, S. Salvans, Z. H. Sam, E. Samadov, M. Sampaio Alves, A. Sanad, S. SanchezFonseca, A. Sanchez Teran, S. Sanchez Ussa, O. Sandli, H. Sanfey, J. Sanghera, I Sani, M. Santafe Guerrero, M. Sante Fornasiero, O. Santes Jasso, I. Santos Pereira, H. Santos Sousa, A. Saratzis, A. Saratzis, A. Sarmiento Alarcon, T. Saumtally, R. Sayyed, M. Schettino, L. Schleimer, T. Schmidt, K. Schondffelt, M. Schwab, A. Scott, H. Searle, L. Sebopelo, B. Seeglier, R. Seishima, D. Semenvov, A. Senent-Boza, J. Sepulveda, M. Serenari, M. SerranoNavidad, I Sert, E. Sewart, A. Sgro, V Shadrina, K. Shah, F. Shahid, M. Shalaby, B. Shankar, J. Shapiro, L. Sharma, A. Sheel, A. Shenfine, S. Shenoy, A. Sherif, N. Shetty, R. Shetty, T. C. Sia, D. Sichimba, H. Siddique, I Siddiqui, G. Simkens, J. Simoe, H. Simon, L. Sinan, T. Singh, K. Singh, Y. Singh, L. Sinha, L. Siragusa, T. Sluckin, Y. W. Smart, H. Smith, K. Smith, L. Smits, C. Sneep-vanKessel, C. Sohrabi, A. Soma, L. Sooriyapiragasam, K. Soreide, M. Sparavigna, R. Spence, N. Spencer, H. Spiers, A. Spinelli, J. Sprakel, S. Sravanam, M. Srinivasan, R. Srinivasan, A. Staniszewska, S. J. Stanworth, K. Stasinos, R. J. C. Steele, I Steinholt, M. Steinruecke, B-J Stephen, J. Stijns, M. Still, W. Stupalkowska, S. Subba, V. V. Subbotin, P. Sucharitkul, A. Sudarsanam, D. Sudhamsh Reddy, T. Suhardja, M. Suliman, M. Sund, T. Tamas, A. Sunilkumar, N. Suresh, S. Sussmes, P. Sutton, J. Syltern, A. Taha, Y. Takamizawa, A. B. Takoutsing Dongmo, L. Tan, J. L. Tan, K. Tan, E. Tan, A. Tan YongHui, A. Tanase, A. Tariverdiev, A. Tasnem, C. Tatar, E. Tay, P. Tejedor, G. Tesfaye, F. Tetinou, C. Thorpe, A. Thyo, D. Tlelo Amastal, M. Tolani, K. Tolga Saracoglu, T. Tolgyes, J. Tong, L. Torrent Jansa, S. Toscano Igartua, M. R. Tovani Palone, H. Traff, J. Trevis, W. Tummers, A. Tur, I Turchenko, V Uche, A. Uddin, N. Udonsak, M. Ullah, T. Urbonas, C. Uwins, E. Uy Magadia, A. UzairQureshi, K. Uzun, P. Vadim, G. Valarche, R. A. Valdez Gonzalez, M. Vallee, D-J Van Beek, A. S. van Dalen, D. van den Hondel, E. van der Stok, M. van Dorp, S. van Oostendorp, E. van Praag, J. VanRees, L. van Silfhout, Z. Varga, S. Varghese, C. Varghese, J. Varghese, A-M Vasilica, X. Vasquez Ojeda, E. Vega, S. Vehler, R. Venchiarutti, S. Vengatesan, M. Venn, D. Verma, G. VianeyPartida Nava, D. Victoria, P. Vieira, M. E. Vilar Alvarez, D. Vinci, G. Viscasillas Pallas, M. Viswanath, J. Vivanco, J. Vo, D. Volchanski, T. Voron, Y. Voronovskyi, J. Vu, M. Wadhwa, S. Wadhwa, G. Wagner, M. Wallace, Y. Y. Wang, J. Wang, A. Wani, K. Wanigasooriya, S. Wanjara, N. Wanjiku, C. Warner, T. Wei Leow, T. Weiser, M. Weisters, M. J. Wellington, C. Wells, C. Wenzelberg, D. Wettstein, A. Wezel, L. Wheldon, L. Widmer, M. Wilson, S. Wigmore, T. Wijayaratne, M. Wijeyaratne, B. P. L. Wijnhoven, R. Wilkin, E. Williams, F. Willis, D. Winter, M. M. Wirsik, B. Wishah, G. Wong, W. J. Wong, K. Wong, K-Y Wong, D. Worku, E. Wright, J. Wright, O. Wroe Wright, S. Xenacki, W. Xia, W. Xu, Z. Xu, A. Yalcinkaya, W. Yang, P-C Yang, A. Yanishev, A. Yanzon de la Torre, H. Yao, E. Yaqoob, S. Yen Ling Quake, D. Yeo, B. Yeom, D. Yershov, M. Yiasemidou, A. Yildiz, A. Yiu, M. Yoav, E. Yong, R. Yoshimura, M. U. Younis, Z. Younis Ringshawl, M. Youssef, Y. Yue, S. Yuen, R. Yuldashev, C. Yurttas, B. Yves, A. Zaborowski, R. Zackeri, A. Zafar, W. Zahra, A. Zaidi, S. Zainudin, R. Zakeri, I Zamora, A. T. Zamora, M. Zawistowski, G. Zbikowska, W. Zegers, S. Zehra, A. Zeyra, Z. Zhagniyev, L. G. Zhukova, M. Zivanovic, J. Zmuc, M. Zope, A. Zubayraeva, B. Zucker

Summary: The COVID-19 pandemic has significantly impacted global surgical practice, posing various challenges for surgeons worldwide. However, collaborative efforts by global surgical multidisciplinary teams are underway to address these challenges and explore the future of surgery post-COVID-19, emphasizing the need for establishing multidisciplinary ethics committees and fostering innovative leadership and collaboration.

BRITISH JOURNAL OF SURGERY (2021)

添加到收藏夹
Article Medicine, General & Internal

Fallopian Tube Torsion Secondary to Paraovarian Fimbrial Cyst: A Difficult to Diagnose and a Rare Cause of Acute Abdomen in Adolescent

Shamail Syed, Ayesha Amin, Muneeb Ullah

Summary: Fallopian tube torsion secondary to paraovarian or paratubal cyst is a rare gynecological cause of acute abdomen, with no distinctive signs or characteristic features on radiological imaging. While paraovarian cysts are usually asymptomatic, they can sometimes lead to torsion of the fallopian tube, requiring surgical intervention to prevent complications.

CUREUS JOURNAL OF MEDICAL SCIENCE (2021)

添加到收藏夹
Article Medicine, General & Internal

Management of Closed Tibal Shaft Fractures with Reamed Interlocking Nail

Shakeel Ahmad Shah, Muhammad Shoaib Zardad, Abdus Saboor, Imtiaz Muhammad, Maaz Ullah

Summary: The study confirmed the effectiveness and safety of reamed interlocking nail in the management of closed tibial shaft fractures, with an overall union rate of 93.75% and lower morbidity among cases demonstrated.

PAKISTAN JOURNAL OF MEDICAL & HEALTH SCIENCES (2021)

添加到收藏夹
Article Medicine, General & Internal

Supracondylar Fracture of Humerus in Children Treated with Closed Reduction and Percutaneous Cross Pinning VS Lateral Pinning

Muhammad Shoaib Zardad, Shakeel Ahmad Shah, Muhammad Younas, Maaz Ullah, Imtiaz Muhammad, Kamran Asghar

Summary: This study compared the outcomes of percutaneous cross pinning and two lateral pinning in the treatment of closed reduction supracondylar fracture of humerus in children. The results showed that both techniques are safe and effective, with no significant difference in outcomes observed between the two groups.

PAKISTAN JOURNAL OF MEDICAL & HEALTH SCIENCES (2021)

添加到收藏夹
暂无数据
研讨会 海报 问题 讨论圈 基金 期刊 论文 科研社交 资讯集成 审稿人 关于我们 常见问题 移动App 隐私条款 使用条款
© Peeref 2019-2024. All rights reserved.