4.6 Article

MULTISCALE MODELING OF THE RESPIRATORY TRACT

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出版社

WORLD SCIENTIFIC PUBL CO PTE LTD
DOI: 10.1142/S0218202510004155

关键词

Navier-Stokes equations; local existence; coupling of models; ventilation process; Finite Element Method

资金

  1. CINIM project LePoumonVousDisJe

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We propose here a decomposition of the respiratory tree into three stages which correspond to different mechanical models. The resulting system is described by the Navier-Stokes equation coupled with an ODE (a simple spring model) representing the motion of the thoracic cage. We prove that this problem has at least one solution locally in time for any data and, in the special case where the spring stiffness is equal to zero, we obtain an existence result globally in time provided that the data are small enough. The behavior of the global model is illustrated by three-dimensional simulations.

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