Article
Metallurgy & Metallurgical Engineering
Ji-Woo Gu, Jae-Young Bae, Guangzhe Li, Hae Won Hwang, So-Hyeon Lee, Sung-Geun Choi, Ju-Young Kim, Myoung-Ryul Ok, Yu-Chan Kim, Seung-Kyun Kang
Summary: In this study, a sputtered Mg-Zn binary alloy thin film with enhanced corrosion resistance was introduced for biodegradable electronics. The results showed that the Mg-3Zn alloy electrode exhibited improved yield strain, elongation, and biocompatibility.
JOURNAL OF MAGNESIUM AND ALLOYS
(2023)
Article
Materials Science, Multidisciplinary
Wei Zai, Shuo Sun, H. C. Man, Jianshe Lian, Yusheng Zhang
Summary: In this study, a series of calcium phosphate (CaP) coatings were synthesized on Mg66Zn30Ca4 metallic glass via the electrodeposition method to improve its corrosion resistance and bioactivity. The mechanisms of formation and anti-corrosion effects of CaP coatings were proposed, and the relationship between the composition of the CaP solution and the precipitation process of calcium phosphate was accurately described.
MATERIALS CHEMISTRY AND PHYSICS
(2022)
Article
Materials Science, Multidisciplinary
Meysam Mohammadi-Zerankeshi, Mohammad Zohrevand, Reza Alizadeh
Summary: Developing antibacterial biodegradable Mg alloys is crucial for preventing infection and inflammation during healing. Mg-2Ag alloy is a suitable candidate with good biocompatibility and antibacterial activity, but its fast degradation rate hinders its clinical application. To address this issue, a hydrothermal coating technique was used to synthesize a barrier coating on the Mg-2Ag alloy using distilled water. The microstructure of the substrate played a vital role in the coating quality and degradation behavior, with the solution-treated alloy showing improved corrosion resistance compared to the as-cast alloy due to its homogenized microstructure and formation of a more compact and integrated coating.
Article
Metallurgy & Metallurgical Engineering
Jiawen Si, Hongzhou Shen, Hongwei Miao, Yuan Tian, Hua Huang, Jun Shi, Guangyin Yuan, Guofang Shen
Summary: In this study, a biodegradable membrane with guided bone regeneration (GBR) was successfully developed using a Mg-2.0Zn-1.0Gd alloy (wt.%, MZG) membrane with Ca-P coating. The membrane demonstrated enhanced hydrophilicity, good cytocompatibility, excellent antibacterial effect, and improved new bone formation, indicating great potential for clinical application as GBR membranes.
JOURNAL OF MAGNESIUM AND ALLOYS
(2021)
Article
Nanoscience & Nanotechnology
Zeinab Savaedi, Hamed Mirzadeh, Rouhollah Mehdinavaz Aghdam, Reza Mahmudi
Summary: Shear punch testing was used to evaluate the superplasticity of a hot rolled fine-grained Mg-3Zn-0.5RE-0.5Zr (ZEK300) alloy. The alloy exhibited regions I, II, and III of deformation behavior typical of superplastic materials, with a grain size of 4.5 μm. In region II, the strain rate sensitivity indices of the ZEK300 alloy were determined to be 0.51, 0.48, and 0.41 at temperatures of 350, 400, and 450 degrees C, respectively. The average activation energy of 87.6 kJ mol-1 suggests that grain boundary sliding (GBS) facilitated by grain boundary diffusion is the dominant deformation mechanism.
MATERIALS SCIENCE AND ENGINEERING A-STRUCTURAL MATERIALS PROPERTIES MICROSTRUCTURE AND PROCESSING
(2023)
Article
Chemistry, Physical
Yi Zhang, Xiaohui Feng, Qiuyan Huang, Yingju Li, Yuansheng Yang
Summary: The Mg-3Zn-0.2Ca alloy fabricated by directional solidification exhibited highly anisotropic mechanical and corrosion properties. The anisotropy in mechanical properties was attributed to the activation of different deformation mechanisms, while the anisotropic elastic modulus was due to the difference in atomic bonding strengths at different crystallographic planes. Additionally, the corrosion resistance of the alloy also showed anisotropy, with the specimen taken along LD direction showing superior resistance.
JOURNAL OF ALLOYS AND COMPOUNDS
(2022)
Article
Chemistry, Physical
Nuria Pulido-Gonzalez, Sonia Garcia-Rodriguez, Belen Torres, Joaquin Rams
Summary: The wear behavior of the Mg-3wt.% Zn-0.4wt.% Ca (ZX30) alloy was investigated under dry sliding conditions using AZ31 alloy discs as counterparts. The ZX30 alloy was tested in different states: as-cast, solution-treated, peak-aged, and over-aged. Wear rates and friction coefficients were measured at various loads and sliding speeds. Abrasion and oxidation were identified as the predominant wear mechanisms, with the presence of aluminum oxides indicating adhesive wear. The wear behavior of the ZX30 alloy exhibited a higher susceptibility to oxidative wear compared to other Mg alloys, with a strong influence of observed microstructure.
Article
Materials Science, Ceramics
Kenshiro Takaishi, Shigeomi Takai, Takeshi Yabutsuka
Summary: Octacalcium phosphate (OCP) coating was formed on the surface of Mg-Al-Zn-Ca alloy (AZX612) through anodic oxidation and subsequent immersion in a supersaturated aqueous solution containing phosphate and calcium ion. The formed OCP layer consists of an inner layer of fine crystallites and an outer layer of large crystallites, and the inner layer remains on the alloy even after ultrasonication process. AZX612 treated with both anodic oxidation and subsequent OCP coating process exhibits higher corrosion resistance than those treated with only anodic oxidation.
JOURNAL OF THE CERAMIC SOCIETY OF JAPAN
(2022)
Article
Materials Science, Coatings & Films
Jun Wang, Chaoyang Jin, Di Mei, Yan Ding, Lei Chang, Shijie Zhu, Liguo Wang, Yashan Feng, Shaokang Guan
Summary: This study investigated the use of a biodegradable Zn-modified calcium phosphate coating to improve the biocompatibility of Mg-Zn-Ca alloy via dual-pulse electrodeposition. The results showed that the non-stoichiometric Zn-modified coating is biodegradable, has a protective effect, and enhances cellular response to the implant's surface. Additionally, the introduction of Zn changes the formation mechanism of the coating and increases the apatite formation rate.
SURFACE ENGINEERING
(2021)
Article
Engineering, Biomedical
Da-Wang Zhao, Chun-Miao Du, Kang-Qing Zuo, Yi-Xiang Zhao, Xiao-Qian Xu, Yi-Bo Li, Shuai Tian, Hong-Ru Yang, Yu-Peng Lu, Lei Cheng, Gui-Yong Xiao
Summary: Zinc alloys are a new generation material for orthopedic applications due to their physiological effects and degradation properties. However, excessive release of zinc ions during degradation and the inflammatory microenvironment hinder osseointegration. Therefore, it is crucial to modulate the release rate of zinc alloys and give them anti-inflammatory and osteogenic effects through surface modification technology.
ADVANCED HEALTHCARE MATERIALS
(2023)
Article
Chemistry, Physical
Xin Yu, Yang Bai, Bing Ye, Liyang Wang, Beibei Zhao, Xiangyang Kong
Summary: The thermal stability and grain growth kinetics of a high-pressure die casting Mg-6Y-3Zn-1Al alloy with long-period stacking ordered phase were studied through subsequent annealing at different temperatures. The results showed that the microstructure of the alloy was thermally stable up to 450 degrees C. The grain growth kinetics between 450 degrees C and 550 degrees C followed a kinetic equation, and the grain growth exponent varied with temperature. The activation energy values indicated that bulk diffusion was the main grain growth mechanism. The alloy exhibited excellent thermal stability below 500 degrees C and the microstructure evolution was influenced by the dissolution of the long-period stacking ordered phase.
JOURNAL OF ALLOYS AND COMPOUNDS
(2022)
Review
Metallurgy & Metallurgical Engineering
G. S. Hikku, C. Arthi, R. B. Jeen Robert, K. Jeyasubramanian, R. Murugesan
Summary: Developing biodegradable orthopedic implants is important as it can overcome the toxicity of non-degradable implants and is beneficial for the human body. Magnesium plays a key role in producing biodegradable implants due to its characteristic degradation nature, although it has a higher corrosion rate in the biological environment.
JOURNAL OF MAGNESIUM AND ALLOYS
(2022)
Review
Metallurgy & Metallurgical Engineering
G. S. Hikku, C. Arthi, R. B. Jeen Robert, K. Jeyasubramanian, R. Murugesan
Summary: There is a growing interest in the development of biodegradable orthopedic implants globally, with magnesium (Mg) playing a major role due to its characteristic degradation nature. However, the high corrosion rate and the release of H-2 gas leading to cavity formation are primary downsides of using Mg implants.
JOURNAL OF MAGNESIUM AND ALLOYS
(2022)
Review
Chemistry, Applied
Yingchao Xu, Yunting Guo, Guangyu Li, Jianshe Lian
Summary: Phytic acid coating can improve the corrosion resistance of magnesium alloy, possess osteogenic inducement and environmental friendliness, and plays a significant role in improving the integrity of temporary repair implants for implant materials.
PROGRESS IN ORGANIC COATINGS
(2022)
Review
Chemistry, Applied
Yingchao Xu, Yunting Guo, Guangyu Li, Jianshe Lian
Summary: This paper reviews the research progress of phytic acid (PA) coating on biodegradable magnesium (Mg) alloys. The PA conversion coating can improve the corrosion resistance of the Mg matrix while also promoting osteogenesis and being environmentally friendly. The article discusses the structure of PA, the factors influencing the coating, and the strategy of combining with other coatings to enhance its performance.
PROGRESS IN ORGANIC COATINGS
(2022)
Article
Materials Science, Biomaterials
Mohammadreza Kasravi, Alireza Yaghoobi, Tahereh Tayebi, Mahsa Hojabri, Abdolkarim Talebi Taheri, Fatemeh Shirzad, Bahram Jambar Nooshin, Radman Mazloomnejad, Armin Ahmadi, Fatemeh A. Tehrani, Ghasem Yazdanpanah, Mohammad Hadi Farjoo, Hassan Niknejad
Summary: As a promising approach in translational medicine, the decellularization of discarded livers to produce bioscaffolds that support recellularization has potential in overcoming the limitations of conventional liver transplantation. In this study, the researchers investigated the use of matrix metalloproteinase (MMP) inhibition to preserve the extracellular matrix (ECM) during liver decellularization. The results demonstrated that the application of an MMP inhibitor significantly improved the preservation of ECM components and mechanical properties of the bioscaffolds, which supported cell viability and function in vitro. The study also confirmed that the MMP inhibition led to the inhibition of MMP2 and MMP9, providing a novel method to enhance ECM preservation during liver decellularization.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Mohammadsadegh Nadimifar, Weiguang Jin, Clara Coll-Satue, Gizem Bor, Paul Joseph Kempen, Ali Akbar Moosavi-Movahedi, Leticia Hosta-Rigau
Summary: This study presents a metal-phenolic self-assembly approach that can prepare nanoparticles fully made of hemoglobin. The nanoparticles exhibit good oxygen binding and releasing capabilities.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jyoti Kumari, Roel Hammink, Jochem Baaij, Frank A. D. T. G. Wagener, Paul H. J. Kouwer
Summary: Fibrosis is the formation of fibrous connective tissue in response to injury, leading to organ dysfunction. A novel hybrid hydrogel combining synthetic polyisocyanide with hyaluronic acid has been developed, showing strong antifibrotic properties.
BIOMATERIALS ADVANCES
(2024)
Letter
Materials Science, Biomaterials
Melissa Machado Rodrigues, Cristian Padilha Fontoura, Charlene Silvestrin Celi Garcia, Sandro Tomaz Martins, Joao Antonio Pegas Henriques, Carlos Alejandro Figueroa, Mariana Roesch Ely, Cesar Aguzzoli
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jessica Polak, David Sachs, Nino Scherrer, Adrian Suess, Huan Liu, Mitchell Levesque, Sabine Werner, Edoardo Mazza, Gaetana Restivo, Mirko Meboldt, Costanza Giampietro
Summary: Human skin equivalents (HSEs) play a crucial role in tissue engineering. This study introduces a 3D-printed culture insert to apply a static radial constraint on HSEs and examines its effects on tissue characteristics. The results show that the diameter of the culture insert significantly influences tissue contraction, fibroblast and matrix organization, keratinocyte differentiation, epidermal stratification, and basement membrane formation. This study provides important insights for the design of skin tissue engineering.
BIOMATERIALS ADVANCES
(2024)
Review
Materials Science, Biomaterials
Shiliang Chen, Tianming Du, Hanbing Zhang, Jing Qi, Yanping Zhang, Yongliang Mu, Aike Qiao
Summary: This paper reviewed the primary methods for improving the overall properties of biodegradable zinc stents. It discussed the mechanical properties, degradation behavior, and biocompatibility of various improvement strategies. Alloying was found to be the most common, simple, and effective method for improving mechanical properties. Deformation processing and surface modification further improved the mechanical properties and biological activity of zinc alloys. Meanwhile, structural design could endow stents with special properties. Manufacturing zinc alloys with excellent properties and exploring their interaction mechanism with the human body are areas for future research.
BIOMATERIALS ADVANCES
(2024)