Review
Biochemistry & Molecular Biology
Yunwei Niu, Jiahe Wu, Yanxiang Kang, Pingli Sun, Zuobing Xiao, Di Zhao
Summary: Magnetic chitosan hydrogels are a type of organic-inorganic composite material that combines the characteristics of magnetic materials and natural polysaccharides. These hydrogels, which are made by adding magnetic nanoparticles to chitosan, have improved mechanical strength and exhibit magnetic thermal effects, targeting capabilities, magnetically-sensitive release characteristics, and easy separation and recovery. They have been used in various applications including drug delivery, magnetic resonance imaging, mag-netothermal therapy, and adsorption of heavy metals and dyes.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Applied
Elizangela H. Fragal, Vanessa H. Fragal, Elisangela P. Silva, Alexandre T. Paulino, Edson C. da Silva Filho, Marcos R. Mauricio, Rafael Silva, Adley F. Rubira, Edvani C. Muniz
Summary: This review presents recent advances in polysaccharide-based magnetic hydrogels as smart platforms for various biomedical applications, covering their synthesis methods, synergic properties, and contributions in drug delivery, tissue regeneration, and hyperthermia therapy.
CARBOHYDRATE POLYMERS
(2022)
Review
Chemistry, Inorganic & Nuclear
David Vokoun, Sneha Samal, Ivo Stachiv
Summary: Magnetic Force Microscopy (MFM) is a tool that allows for magnetic property characterization with submicron resolution, without the need for extensive sample surface preparation. It can be operated under various temperatures and environmental conditions, making it a widely used technique for characterizing magnetic materials and applications in biomedical and biological fields.
Review
Engineering, Multidisciplinary
Kun Li, Junwei Xu, Ping Li, Yubo Fan
Summary: Magnetic ordered materials based on MNPs have unique advantages in biomedical applications, and future research should focus on safety, functionality, and structural diversity for interdisciplinary studies.
COMPOSITES PART B-ENGINEERING
(2022)
Review
Chemistry, Multidisciplinary
Pedro Lavrador, Marco R. Esteves, Vitor M. Gaspar, Joao F. Mano
Summary: Recent advances in the design of stimuli-responsive nanocomposite hydrogels have expanded their potential for operating as advanced systems in various biomedical applications, benefitting from tailored single or multi-responsiveness. The combination of hydrogels and nanoparticles showcases an intrinsic ability to react to external or internal/physiological stimuli, developing intelligent systems with application-oriented features.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Review
Materials Science, Multidisciplinary
Jiwei Li, Yujie Feng, Weichao Chen, Shaohua Zhang, Jianwei Ma, Shaojuan Chen, Shangpeng Liu, Chengbo Cao, Yuankai Zhang
Summary: This review focuses on the structural design and antibacterial mechanisms of electroactive materials, including electrochemical materials, conductive materials, piezoelectric materials, and micro-batteries/galvanic couples. It also describes the biomedical applications of electroactive antibacterial materials in various areas such as bone tissue engineering, wound healing, medical catheters, oral healthcare, and wearable devices. The future challenges and perspectives associated with electroactive antibacterial materials are discussed. In summary, electroactive materials offer a promising platform for fighting bacterial infections and play a crucial role in the field of biomedicine.
PROGRESS IN MATERIALS SCIENCE
(2023)
Review
Chemistry, Multidisciplinary
Suyoung Lee, Lam Tan Hao, Jeyoung Park, Dongyeop X. Oh, Dong Soo Hwang
Summary: Nanochitin and nanochitosan, as multiscale materials, have attracted attention for their broad range of applications. This article highlights the recent developments in multiscale-dependent material properties and their applications, focusing on biomedical, industrial, and environmental fields.
ADVANCED MATERIALS
(2023)
Review
Chemistry, Multidisciplinary
Yuzheng Wu, Pei Liu, Babak Mehrjou, Paul K. Chu
Summary: The discovery of antibiotics has saved many lives, but antibiotic-resistant bacteria have become a problem in modern medicine. To address this issue, researchers are developing smart antibacterial materials to improve sterilization and reduce the risk of drug resistance. Interdisciplinary collaboration is crucial for the research and development of these materials.
ADVANCED MATERIALS
(2023)
Review
Chemistry, Multidisciplinary
Wenjun Wang, Jianhua Li, Hong Liu, Shaohua Ge
Summary: Ferroelectric materials with various properties such as piezoelectricity, pyroelectricity, inverse piezoelectricity, nonlinear optics, ferroelectric-photovoltaics, etc., are gaining attention in biomedicine due to their ability to interact with force, heat, electricity, and light to generate electrical, mechanical, and optical signals. Their versatile nature makes them advantageous in biosensing, acoustics tweezer, bioimaging, therapeutics, tissue engineering, and stimulating biological functions. Challenges and prospects for the future development of ferroelectric materials in biomedical applications are discussed.
Review
Chemistry, Physical
Swati Panda, Sugato Hajra, Krystian Mistewicz, Pichaya In-na, Manisha Sahu, P. Mary Rajaitha, Hoe Joon Kim
Summary: This article introduces the application of piezoelectric energy harvesters (PEHs) in biomedical and implantable energy harvesting devices. It provides a detailed summary of various piezoelectric biomaterials, device designs, and potential applications, while outlining the future challenges and roadmap for development.
Article
Chemistry, Multidisciplinary
Vivian R. Feig, Eva Remlova, Benjamin Muller, Johannes L. P. Kuosmanen, Nikhil Lal, Anna Ginzburg, Kewang Nan, Ashka Patel, Ahmad Mujtaba Jebran, Meghana Prabhu Bantwal, Niora Fabian, Keiko Ishida, Joshua Jenkins, Jan-Georg Rosenboom, Sanghyun Park, Wiam Madani, Alison Hayward, Giovanni Traverso
Summary: Actively triggerable materials allow for precise control over the lifetime of biomedical technologies and adaptation to unforeseen circumstances. This study demonstrates the use of a biocompatible gallium-indium alloy to trigger the breakdown of aluminum and showcases three possible applications of actively triggerable metals in biomedicine.
ADVANCED MATERIALS
(2023)
Article
Chemistry, Physical
Mina Naghdi, Mahsa Ghovvati, Navid Rabiee, Sepideh Ahmadi, Nikzad Abbariki, Soheil Sojdeh, Amirhossein Ojaghi, Mojtaba Bagherzadeh, Omid Akhavan, Esmaeel Sharifi, Mohammad Rabiee, Mohammad Reza Saeb, Keivan Bolouri, Thomas J. Webster, Ehsan Nazarzadeh Zare, Ali Zarrabi
Summary: Tissue engineering and regenerative medicine have addressed the challenges of repairing and regenerating damaged organs and tissues, and nanotechnology has played a crucial role in advancing tissue regeneration science. Magnetic nanostructures have emerged as promising materials for tissue regeneration, but their potential has not been extensively reviewed.
ADVANCES IN COLLOID AND INTERFACE SCIENCE
(2022)
Review
Biochemistry & Molecular Biology
De-qiang Li, Jun Li, Hui-lin Dong, Xin Li, Jia-qi Zhang, Shri Ramaswamy, Feng Xu
Summary: Natural macromolecules, such as pectin, are attracting attention for their biocompatibility, low toxicity, and biodegradability in biomedical and drug delivery applications. Components like rhamnogalacturonan-II in pectin play a crucial role in biomedical activities. The presence of hydroxyl and carboxyl groups in pectin contributes to its favorable properties for these applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Review
Chemistry, Multidisciplinary
Mongur Hossain, Biao Qin, Bo Li, Xidong Duan
Summary: This article focuses on the recent progress of 2D magnetic materials in synthesis, characterization, properties, and spintronic applications. It outlines growth techniques, characterization methods for magnetic properties, as well as physical properties and device applications. Insights on current and future issues in this field are also provided.
Article
Materials Science, Multidisciplinary
Xiaoyuan Dong, Fengqiang Liu, Liming Wang, Lihui Xu, Hong Pan, Junhong Qi
Summary: A long-lasting power source is crucial for the sustainable operation of implanted medical devices. Nanogenerators, which convert micro-/nano-scale mechanical energy into electricity, have shown great promise for biomedical applications due to their simple configuration, high efficiency, biocompatibility, and biomimetic properties. This manuscript reviews the recent developments of nanogenerators in biomedical applications, including their working mechanisms, specific applications in various medical fields, and potential solutions for future challenges.
MATERIALS TODAY COMMUNICATIONS
(2023)
Article
Materials Science, Biomaterials
Mohammadreza Kasravi, Alireza Yaghoobi, Tahereh Tayebi, Mahsa Hojabri, Abdolkarim Talebi Taheri, Fatemeh Shirzad, Bahram Jambar Nooshin, Radman Mazloomnejad, Armin Ahmadi, Fatemeh A. Tehrani, Ghasem Yazdanpanah, Mohammad Hadi Farjoo, Hassan Niknejad
Summary: As a promising approach in translational medicine, the decellularization of discarded livers to produce bioscaffolds that support recellularization has potential in overcoming the limitations of conventional liver transplantation. In this study, the researchers investigated the use of matrix metalloproteinase (MMP) inhibition to preserve the extracellular matrix (ECM) during liver decellularization. The results demonstrated that the application of an MMP inhibitor significantly improved the preservation of ECM components and mechanical properties of the bioscaffolds, which supported cell viability and function in vitro. The study also confirmed that the MMP inhibition led to the inhibition of MMP2 and MMP9, providing a novel method to enhance ECM preservation during liver decellularization.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Mohammadsadegh Nadimifar, Weiguang Jin, Clara Coll-Satue, Gizem Bor, Paul Joseph Kempen, Ali Akbar Moosavi-Movahedi, Leticia Hosta-Rigau
Summary: This study presents a metal-phenolic self-assembly approach that can prepare nanoparticles fully made of hemoglobin. The nanoparticles exhibit good oxygen binding and releasing capabilities.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jyoti Kumari, Roel Hammink, Jochem Baaij, Frank A. D. T. G. Wagener, Paul H. J. Kouwer
Summary: Fibrosis is the formation of fibrous connective tissue in response to injury, leading to organ dysfunction. A novel hybrid hydrogel combining synthetic polyisocyanide with hyaluronic acid has been developed, showing strong antifibrotic properties.
BIOMATERIALS ADVANCES
(2024)
Letter
Materials Science, Biomaterials
Melissa Machado Rodrigues, Cristian Padilha Fontoura, Charlene Silvestrin Celi Garcia, Sandro Tomaz Martins, Joao Antonio Pegas Henriques, Carlos Alejandro Figueroa, Mariana Roesch Ely, Cesar Aguzzoli
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jessica Polak, David Sachs, Nino Scherrer, Adrian Suess, Huan Liu, Mitchell Levesque, Sabine Werner, Edoardo Mazza, Gaetana Restivo, Mirko Meboldt, Costanza Giampietro
Summary: Human skin equivalents (HSEs) play a crucial role in tissue engineering. This study introduces a 3D-printed culture insert to apply a static radial constraint on HSEs and examines its effects on tissue characteristics. The results show that the diameter of the culture insert significantly influences tissue contraction, fibroblast and matrix organization, keratinocyte differentiation, epidermal stratification, and basement membrane formation. This study provides important insights for the design of skin tissue engineering.
BIOMATERIALS ADVANCES
(2024)
Review
Materials Science, Biomaterials
Shiliang Chen, Tianming Du, Hanbing Zhang, Jing Qi, Yanping Zhang, Yongliang Mu, Aike Qiao
Summary: This paper reviewed the primary methods for improving the overall properties of biodegradable zinc stents. It discussed the mechanical properties, degradation behavior, and biocompatibility of various improvement strategies. Alloying was found to be the most common, simple, and effective method for improving mechanical properties. Deformation processing and surface modification further improved the mechanical properties and biological activity of zinc alloys. Meanwhile, structural design could endow stents with special properties. Manufacturing zinc alloys with excellent properties and exploring their interaction mechanism with the human body are areas for future research.
BIOMATERIALS ADVANCES
(2024)