期刊
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS
卷 33, 期 1, 页码 340-346出版社
ELSEVIER
DOI: 10.1016/j.msec.2012.08.048
关键词
Porous ceramics; Suspensions; Hydroxyapatite; Ice-templated method; Biomedical applications
资金
- Ministry of Education of the People's Republic of China [NCET-10-0802]
- National Natural Science Foundation of China [51172288]
- Ph.D. Programs Foundation of Ministry of Education of China [20110162130003]
- Hunan Provincial Natural Science Foundation of China [11JJ1008]
- Hunan Provincial Innovation Foundation for Postgraduate [CX2011B113]
Freeze casting of aqueous suspension was investigated as a method for fabricating hydroxyapatite (HA) porous ceramics with lamellar structures. The rheological properties of HA suspensions employed in the ice-templated process were investigated systematically. Well aligned lamellar pores and dense ceramic walls were obtained successfully in HA porous ceramics with the porosity of 68-81% and compressive strength of 0.9-2.4 MPa. The results exhibited a strong correlation between the rheological properties of the employed suspensions and the morphology and mechanical properties of ice-templated porous HA ceramics, in terms of lamellar pore characteristics, porosities and compressive strengths. The ability to produce aligned pores and achieve the manipulation of porous HA microstructures by controlling the rheological parameters were demonstrated, revealing the potential of the ice-templated method for the fabrication of HA scaffolds in biomedical applications. (c) 2012 Elsevier B.V. All rights reserved.
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