Article
Chemistry, Multidisciplinary
Phil Opitz, Laura Besch, Martin Panthoefer, Anke Kabelitz, Ronald E. Unger, Franziska Emmerling, Mihail Mondeshki, Wolfgang Tremel
Summary: This study reports a protein-free formation of bone-like apatite from amorphous precursors through ball-milling. Mg2+ ions are crucial to achieve complete amorphization of CaCO3, promoting cell growth through stimulating cell viability ex vivo.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Article
Chemistry, Physical
Suzana Inkret, Marija Curlin, Kristina Smokrovic, Nikolina Kalcec, Nikolina Peranic, Nadica Maltar-Strmecki, Darija Domazet Jurasin, Maja Dutour Sikiric
Summary: This study investigated the influence of different stabilizing agents on the precipitation of calcium phosphates composites with silver nanoparticles (AgNPs). It was found that AgNPs can modify the precipitation process of calcium phosphates, and the precipitation conditions can be fine-tuned by choosing the appropriate stabilizing agent. This is of special interest for the preparation of biomaterials.
Article
Chemistry, Multidisciplinary
Agne Kizalaite, Vytautas Klimavicius, Vytautas Balevicius, Gediminas Niaura, Andrei N. Salak, Jen-Chang Yang, Sung Hun Cho, Tomoyo Goto, Tohru Sekino, Aleksej Zarkov
Summary: Magnesium whitlockite (Mg-WH) is a potential bioceramic material for bone regeneration, but its fabrication using conventional methods is limited due to thermal instability. In this study, Mg-WH was synthesized using a dissolution-precipitation process under hydrothermal conditions. The thermally induced degradation of the synthesized powders was investigated through various analytical techniques, revealing the gradual decomposition of Mg-WH and the coexistence of different phases at elevated temperatures.
Article
Infectious Diseases
Varun Prasath Padmanabhan, Pugalmani Sivashanmugam, Ravichandran Kulandaivelu, Suresh Sagadevan, Balu Sridevi, Rajakumar Govindasamy, Muthu Thiruvengadam
Summary: This study evaluated the application of silver nanoparticles combined with biphasic calcium phosphate (BCP) composites in the field of orthopedics. The results showed that the composites had good osteoconductivity and biocompatibility, and exhibited antibacterial activity against various microorganisms.
Article
Materials Science, Ceramics
Yuki Sugiura, Masanori Horie
Summary: Apatite materials with excellent biocompatibility are suitable bone substitutes, while silver exhibits strong antibacterial properties. By doping silver into the apatite lattice, the composite material can have antibacterial abilities without releasing toxic Ag+ ions. The presence of silver in apatite can be achieved through a solid-solid phase transformation process, maintaining the color and reducing cytotoxicity.
CERAMICS INTERNATIONAL
(2021)
Article
Engineering, Environmental
Anyi Ramirez, Sebastian Perez, Elizabeth Florez, Nancy Acelas
Summary: Phosphorus recovery from water hyacinth shows potential for alleviating future P supply shortage. Thermal treatment of calcium and P-rich water hyacinth at different temperatures results in the formation of hydroxyapatite and other Ca-rich phases, which can be utilized as fertilizer for slow release of P in aqueous solutions and for soil neutralization to support crop growth.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2021)
Article
Chemistry, Multidisciplinary
Cong Sui, Thomas E. Robinson, Richard L. Williams, Neil M. Eisenstein, Liam M. Grover
Summary: Heterotopic ossification (HO) is the pathological formation of bone in soft tissues. The study demonstrates that adenosine triphosphate (ATP) stabilizes amorphous calcium carbonate (ACC) and triggers its rapid crystallization into apatite, suggesting a possible pathway to physiological bone mineralization.
COMMUNICATIONS CHEMISTRY
(2023)
Article
Construction & Building Technology
Greta Ugolotti, Giulia Masi, Elisa Boanini, Enrico Sassoni
Summary: This study evaluated the effects of salt contamination on the performance of two consolidants applied onto mortars. The results showed that DAP had better strengthening ability than NL, but the aggressive salt weathering cycles reduced the performance of the consolidants.
CONSTRUCTION AND BUILDING MATERIALS
(2022)
Article
Engineering, Biomedical
Songzhe Shan, Zhenhang Tang, Kaida Sun, Wenjing Jin, Haihua Pan, Ruikang Tang, Wei Yin, Zhijian Xie, Zhuo Chen, Changyu Shao
Summary: This study proposes a new pathway for collagen fibril mineralization via particle-mediated phase transformation, deepens the understanding of its mechanism, and offers a new strategy for hard tissue repair.
ADVANCED HEALTHCARE MATERIALS
(2023)
Article
Engineering, Biomedical
Kazuo Onuma, Mari M. Saito, Yasuo Yamakoshi, Mayumi Iijima, Yu Sogo, Koichi Momma
Summary: The transformation of soluble calcium phosphates to metastable octacalcium phosphate (OCP) in specific conditions provides a new approach for repairing teeth. The hybrid calcium phosphates produced by this transformation, consisting of HAP cores and highly reactive outer OCP layers, show promise for treating dentin caries.
ACTA BIOMATERIALIA
(2021)
Article
Engineering, Biomedical
Mary Josephine McIvor, Preetam K. Sharma, Catherine E. Birt, Hayley McDowell, Shannon Wilson, Stephen McKillop, Jonathan G. Acheson, Adrian R. Boyd, Brian J. Meenan
Summary: This study demonstrates that Raman spectroscopy can be used to monitor the response of single U-2 OS cells to biomaterials, leading to cell maturation towards natural bone formation, showing distinct spectral changes depending on the type of hydroxyapatite coating used on titanium substrates.
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
(2021)
Article
Engineering, Biomedical
B. Le Gars Santoni, L. Niggli, S. Dolder, O. Loeffel, G. A. Sblendorio, R. Heuberger, Y. Maazouz, C. Staehli, N. Doebelin, P. Bowen, W. Hofstetter, M. Bohner
Summary: This study assessed the effect of small fractions of β-CPP on the in vitro osteoclastic resorption of β-TCP and found that β-CPP fractions significantly inhibited the resorption of β-TCP. The study also examined the impact of β-CPP and HA impurities on the physico-chemical properties of β-TCP powders and sintered cylinders.
BIOACTIVE MATERIALS
(2022)
Article
Chemistry, Inorganic & Nuclear
Yanqiu Wu, Shan Zhang, Lanying Sun, Yupeng Lu, Yanyan Jiang, Guiyong Xiao
Summary: In this study, Sr-doping ll-tricalcium phosphate (ll-Ca3(PO4)2, ll-TCP) nanoparticles were synthesized using the wet chemical method. The effect of Sr2+ doping concentration on the phase composition and evolution of ll-TCP was investigated. It was found that Sr2+ doping reduced the agglomeration of the precursor calcium deficient hydroxyapatite (CDHA) and decreased the particle size of ll-TCP. Furthermore, the impurities in ll-TCP, namely hydroxyapatite (HA) and ll-calcium pyrophosphate (ll-CPP), changed with the increasing Sr2+ doping concentration.
JOURNAL OF SOLID STATE CHEMISTRY
(2023)
Review
Materials Science, Multidisciplinary
Monika Furko, Katalin Balazsi, Csaba Balazsi
Summary: Biocompatible ceramics are vital in bioengineering and have great potential in biomedical and orthopedic fields. Calcium phosphates, particularly hydroxyapatite, are the most suitable bioceramics due to their similarity to human bones. These can be used as bone substitutes, drug carriers, and coatings. However, bioceramics suffer from brittleness and poor mechanical properties. By doping calcium phosphates with active biomolecules and combining them with biopolymers, new possibilities for applications arise. This review explores the recent advancements in calcium phosphate-biopolymer composites, emphasizing their potential in healthcare, bone healing, and orthopedic surgeries.
Article
Materials Science, Ceramics
Hao-Yu Chang, Ying-Cen Chen, Wei-Hsing Tuan, Sseu-Pei Hwang, Li-Kwan Chang, Chia-Jung Wu, Chih-Yi Chen, Po-Liang Lai
Summary: This study developed a biphasic bone graft prepared at low temperature, with high porosity and non-cytotoxicity. Experimental results show that the bone graft can be effectively degraded in vivo and promote bone defect repair.
CERAMICS INTERNATIONAL
(2021)
Article
Engineering, Biomedical
Jintamai Suwanprateeb, Ticomporn Luangwattanawilai, Thunyanun Theeranattapong, Waraporn Suvannapruk, Sorayouth Chumnanvej, Warinkarn Hemstapat
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
(2016)
Article
Engineering, Mechanical
Pataravit Rukskul, Waraporn Suvannapruk, Jintamai Suwanprateeb
RAPID PROTOTYPING JOURNAL
(2020)
Article
Engineering, Biomedical
Ruedee Hemstapat, Waraporn Suvannapruk, Faungchat Thammarakcharoen, Sorayouth Chumnanvej, Jintamai Suwanprateeb
PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE
(2020)
Article
Clinical Neurology
Sorayouth Chumnanvej, Ticomporn Luangwattanawilai, Visut Rawiwet, Jintamai Suwanprateeb, Kasem Rattanapinyopituk, Somkiat Huaijantug, Chaowaphan Yinharnmingmongkol, Ruedee Hemstapat
NEUROLOGICAL RESEARCH
(2020)
Article
Dentistry, Oral Surgery & Medicine
Jirapa Wongpairojpanich, Pennapa Kijartorn, Jintamai Suwanprateeb, Borvornwut Buranawat
Summary: Porous polyethylene has been used in medical applications with good results, leading to the development of a new bilayer porous polyethylene membrane (B-PPM) for alveolar ridge preservation. The clinical efficacy of B-PPM was compared to high-density polytetrafluoroethylene membrane (d-PTFE) in this study, showing similar outcomes between the two groups.
CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH
(2021)
Article
Polymer Science
Arunnee Sanpakitwattana, Waraporn Suvannapruk, Sorayouth Chumnanvej, Ruedee Hemstapat, Jintamai Suwanprateeb
Summary: Oxidized regenerated cellulose/polycaprolactone bilayered composite (ORC/PCL bilayered composite) was investigated as an antibacterial dural substitute. The study found that the concentration of cefazolin loading affected the microstructure of the composite, and the loaded composite had higher density but lower thickness compared to the drug unloaded composite. ORC/PCL bilayered composite could potentially serve as an antibiotic carrier with antibacterial activity.
Article
Infectious Diseases
Chittawee Jiamton, Adinun Apivatgaroon, Saree Aunaramwat, Banchai Chawalitrujiwong, Chaiwat Chuaychoosakoon, Sitthiphong Suwannaphisit, Choen Jirawison, Chonlathan Iamsumang, Pinkawas Kongmalai, Pawaris Sukvanich, Pongtep Na Nakorn, Worawit Ongbumrungphan, Pawin Rattanasumrit, Suthee Tharakulphan, Thanachai Thongtanworapat, Faungchat Thammarakcharoen, Autcharaporn Srion, Jintamai Suwanprateeb, Bancha Chernchujit
Summary: The clinical efficacy and safety of localized antibiotics delivery via impregnated microporous nanohydroxyapatite (nHA-ATB) beads for chronic osteomyelitis treatment were evaluated in this study. The success rate was approximately 98% with improved quality of life for all patients after treatment.
Article
Multidisciplinary Sciences
Autcharaporn Srion, Phee Palanuruksa, Faungchat Thammarakcharoen, Jintamai Suwanprateeb
CHIANG MAI JOURNAL OF SCIENCE
(2020)
Article
Multidisciplinary Sciences
Faungchat Thammarakcharoen, Jintamai Suwanprateeb
CHIANG MAI JOURNAL OF SCIENCE
(2020)
Article
Dentistry, Oral Surgery & Medicine
Ji-Chuan Song, Jintamai Suwanprateeb, Daraporn Sae-Lee, Teerapan Sosakul, Suwadee Kositbowornchai, Poramaporn Klanrit, Waranuch Pitiphat, Saengsome Prajaneh
JOURNAL OF ORAL SCIENCE
(2020)
Article
Dentistry, Oral Surgery & Medicine
Teerapan Sosakul, Pongsatorn Tuchpramuk, Waraporn Suvannapruk, Autcharaporn Srion, Bunyong Rungroungdouyboon, Jintamai Suwanprateeb
JOURNAL OF PERIODONTAL AND IMPLANT SCIENCE
(2020)
Article
Multidisciplinary Sciences
Ji-Chuan Song, Jintamai Suwanprateeb, Darapom Sae-lee, Teerapan Sosakul, Waranuch Pitiphat, Saengsome Prajaneh, Suwadee Kositbowornchai, Boonsong Putraphan
Article
Medicine, Research & Experimental
Jintamai Suwanprateeb, Waraporn Suvannapruk, Watchara Chokevivat, Siripong Kiertkrittikhoon, Nara Jaruwangsanti, Prakit Tienboon
Article
Multidisciplinary Sciences
Faungchat Thammarakcharoen, Jintamai Suwanprateeb
CHIANG MAI JOURNAL OF SCIENCE
(2018)
Article
Engineering, Multidisciplinary
Jintamai Suwanprateeb, Faungchat Thammarakcharoen
INDIAN JOURNAL OF ENGINEERING AND MATERIALS SCIENCES
(2017)
Article
Materials Science, Biomaterials
Mohammadreza Kasravi, Alireza Yaghoobi, Tahereh Tayebi, Mahsa Hojabri, Abdolkarim Talebi Taheri, Fatemeh Shirzad, Bahram Jambar Nooshin, Radman Mazloomnejad, Armin Ahmadi, Fatemeh A. Tehrani, Ghasem Yazdanpanah, Mohammad Hadi Farjoo, Hassan Niknejad
Summary: As a promising approach in translational medicine, the decellularization of discarded livers to produce bioscaffolds that support recellularization has potential in overcoming the limitations of conventional liver transplantation. In this study, the researchers investigated the use of matrix metalloproteinase (MMP) inhibition to preserve the extracellular matrix (ECM) during liver decellularization. The results demonstrated that the application of an MMP inhibitor significantly improved the preservation of ECM components and mechanical properties of the bioscaffolds, which supported cell viability and function in vitro. The study also confirmed that the MMP inhibition led to the inhibition of MMP2 and MMP9, providing a novel method to enhance ECM preservation during liver decellularization.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Mohammadsadegh Nadimifar, Weiguang Jin, Clara Coll-Satue, Gizem Bor, Paul Joseph Kempen, Ali Akbar Moosavi-Movahedi, Leticia Hosta-Rigau
Summary: This study presents a metal-phenolic self-assembly approach that can prepare nanoparticles fully made of hemoglobin. The nanoparticles exhibit good oxygen binding and releasing capabilities.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jyoti Kumari, Roel Hammink, Jochem Baaij, Frank A. D. T. G. Wagener, Paul H. J. Kouwer
Summary: Fibrosis is the formation of fibrous connective tissue in response to injury, leading to organ dysfunction. A novel hybrid hydrogel combining synthetic polyisocyanide with hyaluronic acid has been developed, showing strong antifibrotic properties.
BIOMATERIALS ADVANCES
(2024)
Letter
Materials Science, Biomaterials
Melissa Machado Rodrigues, Cristian Padilha Fontoura, Charlene Silvestrin Celi Garcia, Sandro Tomaz Martins, Joao Antonio Pegas Henriques, Carlos Alejandro Figueroa, Mariana Roesch Ely, Cesar Aguzzoli
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jessica Polak, David Sachs, Nino Scherrer, Adrian Suess, Huan Liu, Mitchell Levesque, Sabine Werner, Edoardo Mazza, Gaetana Restivo, Mirko Meboldt, Costanza Giampietro
Summary: Human skin equivalents (HSEs) play a crucial role in tissue engineering. This study introduces a 3D-printed culture insert to apply a static radial constraint on HSEs and examines its effects on tissue characteristics. The results show that the diameter of the culture insert significantly influences tissue contraction, fibroblast and matrix organization, keratinocyte differentiation, epidermal stratification, and basement membrane formation. This study provides important insights for the design of skin tissue engineering.
BIOMATERIALS ADVANCES
(2024)
Review
Materials Science, Biomaterials
Shiliang Chen, Tianming Du, Hanbing Zhang, Jing Qi, Yanping Zhang, Yongliang Mu, Aike Qiao
Summary: This paper reviewed the primary methods for improving the overall properties of biodegradable zinc stents. It discussed the mechanical properties, degradation behavior, and biocompatibility of various improvement strategies. Alloying was found to be the most common, simple, and effective method for improving mechanical properties. Deformation processing and surface modification further improved the mechanical properties and biological activity of zinc alloys. Meanwhile, structural design could endow stents with special properties. Manufacturing zinc alloys with excellent properties and exploring their interaction mechanism with the human body are areas for future research.
BIOMATERIALS ADVANCES
(2024)