Article
Materials Science, Coatings & Films
Radka Gorejova, Renata Orinakova, Zuzana Orsagova Kralova, Tibor Sopcak, Ivana Sisolakova, Marek Schnitzer, Miroslav Kohan, Radovan Hudak
Summary: Successful acceptance of biomaterials relies on the interaction between their surface and the biological components of the host environment. Surface treatment, such as electrochemical deposition of ceramic coatings, can enhance the integration of orthopedic scaffolds. This study focuses on depositing HAp coatings on additively manufactured titanium specimens with a porous structure.
SURFACE & COATINGS TECHNOLOGY
(2023)
Article
Biotechnology & Applied Microbiology
Yang Sun, Xing Zhang, Mingran Luo, Weifan Hu, Li Zheng, Ruqi Huang, Johannes Greven, Frank Hildebrand, Feng Yuan
Summary: This study successfully fabricated HA coatings on 3D-printed Ti scaffolds, with PSHA scaffolds showing superior bone repair capacity compared to EDHA scaffolds. While the EDHA technology is simpler, improvements are needed due to limitations in crystalline and HA structures.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Physics, Applied
Nooshin Kashi, Mahdi Momeni, Habib Hamidinezhad
Summary: In this study, pure Hydroxyapatite (HA) and Cu-substituted HA (Cu-HA) coatings were prepared on stainless steel substrates using a pulsed laser deposition (PLD) technique. The crystallinity of the films was significantly modified by the percentages of Cu dopants, laser energy, and annealing temperature. The morphology and structural properties of the coatings were analyzed using FESEM, XRD, and Raman spectroscopy. The synthesized films exhibited dense and compact microstructures, and the irregular surface and crystalline structure promoted cell proliferation in medical and biomedical applications.
MODERN PHYSICS LETTERS B
(2022)
Article
Biochemistry & Molecular Biology
Elina Kylmaoja, Jani Holopainen, Faleh Abushahba, Mikko Ritala, Juha Tuukkanen
Summary: Hydroxyapatite (HA) coatings prepared using atomic layer deposition (ALD) show good biocompatibility in terms of cell adhesion and viability, opening up new possibilities for developing improved implant coatings.
Article
Chemistry, Physical
Tomasz Moskalewicz, Maciej Warcaba, Lukasz Cieniek, Maciej Sitarz, Marta Gajewska, Aldo R. Boccaccini
Summary: The study focused on developing composite HA/SA coatings using EPD technique and characterizing their properties. The coatings exhibited different surface morphology and microstructure depending on the HA content in suspension. Surface preparation and HA content significantly influenced the adhesion of the coatings.
APPLIED SURFACE SCIENCE
(2021)
Article
Materials Science, Multidisciplinary
N. Aslan, B. Aksakal, B. Dikici, Z. A. Sinirlioglu
Summary: The effect of HA-based coatings reinforced with rGO on porous-Ti6Al4V alloys in terms of electrochemical corrosion and cell viability was investigated. The results showed that rGO reinforcements reduced the corrosion rate of the scaffolds, and the corrosion rate increased as the porosity content of the scaffolds increased. 0.5 and 1.0wt% rGO-HA coating groups had better cell viability.
JOURNAL OF MATERIALS SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Elina Kylmaoja, Faleh Abushahba, Jani Holopainen, Mikko Ritala, Juha Tuukkanen
Summary: Coating bone implants with hydroxyapatite (HA) has benefits for osseointegration, but there may be differences in monocyte differentiation and material resorption compared to natural bone. In this study, ALD-HA coating on a titanium substrate was compared with bovine bone, and it was found that ALD-HA led to the presence of non-resorbing cells instead of resorbing osteoclasts. The topographical properties of ALD-HA, such as surface roughness, may play a role in this cellular reaction.
Article
Materials Science, Multidisciplinary
Evgeniy V. Orekhov, Andrey Yu. Arbenin, Elena G. Zemtsova, Darya N. Sokolova, Alexandra N. Ponomareva, Maxim A. Shevtsov, Natalia M. Yudintceva, Vladimir M. Smirnov
Summary: Modern materials science is actively developing methods for creating structures with specific ordering. Template synthesis is a widely-used approach, where the structure is ordered based on a template shape. In this study, a template electrochemical method was used to synthesize calcium hydroxyapatite (HAp) coatings, replicating a planar template texture during deposition. The developed approach has potential applications in obtaining micro-ordered hydroxyapatite structures on bone implants, improving their biomedical characteristics.
Article
Materials Science, Multidisciplinary
N. Kashi, M. Momeni, Habib Hamidinezhad
Summary: The study showed that Cu-doped HA thin films enhanced antibacterial properties and promoted apatite growth in simulated body fluid solution. Characterization techniques including FESEM, EDX, XRD, and Raman spectroscopy were used to analyze the samples, indicating that the irregular and crystalline structure of the fabricated films facilitated surface extension and cell proliferation for medical and biomedical applications.
MATERIALS TECHNOLOGY
(2022)
Article
Materials Science, Multidisciplinary
Faleh Abushahba, Nagat Areid, Elina Kylmaeoja, Jani Holopainen, Mikko Ritala, Leena Hupa, Juha Tuukkanen, Timo Naerhi
Summary: This study evaluated the effects of an atomic layer deposition (ALD) hydroxyapatite coating on titanium surfaces. The coating improved surface characteristics, including increased surface free energy and enhanced wetting. The ALD-coated surfaces also demonstrated lower surface roughness. Platelet adhesion was more noticeable on the coated surfaces, indicating enhanced blood coagulation. These findings suggest that the ALD-HA coating can improve the biocompatibility of titanium surfaces.
Article
Materials Science, Multidisciplinary
Sri Rahmadani, Anawati Anawati, Muhammad Dikdik Gumelar, Razie Hanafi, I. Nyoman Jujur
Summary: Bioactive hydroxyapatite (HA) coating was successfully applied on commercially pure Ti using electrophoretic deposition (EPD), with the 30 V coating showing the best corrosion resistance due to high HA grain density and low corrosion current density.
MATERIALS RESEARCH EXPRESS
(2022)
Article
Materials Science, Coatings & Films
Sandeep Singh, Gurpreet Singh, Niraj Bala
Summary: The study fabricated a composite coating of CS-HA-BG-Fe3O4 with bioactivity, high corrosion resistance, and excellent cell proliferation, suitable for biomedical applications.
SURFACE & COATINGS TECHNOLOGY
(2021)
Article
Materials Science, Ceramics
Kunyu Ju, Xingyu Chen, Zhongwei Zhao
Summary: In this study, a micro-arc oxidation (MAO) process with calcium was introduced to improve the interfacial strength of Titanium with a bioceramic hydroxyapatite (HA) coating. The MAO coating comprised porous TiO2 with Ca or CaTiO3, and the HA coating on the MAO coating was confirmed to be plate-like Ca-deficient HA. The MAO coating containing Ca as a connecting interlayer showed promising results in improving the HA adhesion strength with an adhesive strength of 2.326 MPa.
CERAMICS INTERNATIONAL
(2022)
Article
Chemistry, Physical
Nazila Horandghadim, Yashar Ghazanfar-Ahari, Jafar Khalil-Allafi
Summary: In this study, antibacterial implants were developed by incorporating different amounts of multi-walled carbon nanotubes (MWCNTs) with hydroxyapatite-tantalum pentoxide (HA-Ta2O5) and applying them onto NiTi using electrophoretic deposition (EPD) method. The addition of MWCNTs increased the density of the HA-Ta2O5 coating and improved its adhesion strength to NiTi. Furthermore, the MWCNTs enhanced the antibacterial property and electrochemical behavior of the coating.
SURFACES AND INTERFACES
(2022)
Article
Nanoscience & Nanotechnology
Yujia Wei, Maohua Chen, Menghuan Li, Dong Wang, Kaiyong Cai, Zhong Luo, Yan Hu
Summary: In this study, Apt19s-grafted oxidized hyaluronic acid was deposited onto a protein-mediated biomineralization hydroxyapatite coating of titanium, resulting in a functional structure (Ti/HAp/OHA-Apt) that can effectively release Apt19s and enhance the migration, adhesion, and osteogenic differentiation of bone marrow mesenchymal stem cells. The Ti/HAp/OHA-Apt material has the potential to promote bone regeneration.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Chemistry, Physical
Man-Fai Ng, Daniel John Blackwood, Hongmei Jin, Teck Leong Tan
JOURNAL OF PHYSICAL CHEMISTRY C
(2020)
Article
Chemistry, Multidisciplinary
Man-Fai Ng, Daniel John Blackwood, Hongmei Jin, Teck Leong Tan
CHEMISTRY-AN ASIAN JOURNAL
(2020)
Article
Electrochemistry
YanHan Liew, Cem Ornek, Jinshan Pan, Dominique Thierry, Sudesh Wijesinghe, Daniel J. Blackwood
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2020)
Article
Chemistry, Physical
Varun Rai, Kai Peng Lee, Dorsasadat Safanama, Stefan Adams, Daniel John Blackwood
ACS APPLIED ENERGY MATERIALS
(2020)
Article
Energy & Fuels
Yang Gui, Pengcheng Li, Junsong Chen, Baoan Fan, Daniel John Blackwood
Summary: A trimetallic oxide thin film of Ni-Mn-Fe was successfully synthesized vertically on a Ni substrate through a simple cyclic voltammetric electrodeposition method. This unique nanosheet morphology with shear-wall structure exhibited faster kinetics and excellent capacitance performance. By pairing this film with activated carbon, it showed considerable energy density and maintained good performance at different power densities, illuminating three red LEDs under practical conditions.
Article
Green & Sustainable Science & Technology
YanHan Liew, Sudesh Wijesinghe, Daniel J. Blackwood
Summary: The study revealed that aluminum alloy AA5083 is susceptible to localized corrosion after potentiodynamic scanning, with the extent of beta-Al3Mg2 in its microstructure playing a key role. Electrochemical analysis could potentially lead to the development of a technique for evaluating the growth, sensitization, and intergranular corrosion susceptibility of AA5083 components.
Article
Chemistry, Physical
Man-Fai Ng, Daniel John Blackwood, Hongmei Jin, Teck Leong Tan
Summary: Cl-induced passivity breakdown is a major cause of corrosion for ferrous alloys, with MnS inclusions being the preferred sites for pit initiation. The addition of Mo has been shown to effectively mitigate the degradation process, offering a potential way to improve the corrosion resistance of ferrous alloys.
JOURNAL OF PHYSICAL CHEMISTRY C
(2021)
Article
Metallurgy & Metallurgical Engineering
Kai Xiang Kuah, Daniel J. Blackwood, Wee Kit Ong, Mojtaba Salehi, Hang Li Seet, Mui Ling Sharon Nai, Sudesh Wijesinghe
Summary: Binder jet printing is used to produce porous magnesium structures, but the microstructure is detrimental to corrosion performance. Impregnating the pores with hydroxyapatite or polymers greatly improves the corrosion resistance of the binder jet printing samples.
JOURNAL OF MAGNESIUM AND ALLOYS
(2022)
Article
Chemistry, Physical
Mohsen Saeedikhani, Sareh Vafakhah, Daniel J. Blackwood
Summary: In this study, the finite element method was used to simulate the response of the scanning vibrating electrode technique (SVET) on an iron-zinc cut-edge sample. It was discovered that the presence of a diffusion layer affected the measured localized corrosion rates using SVET. To address this difference, a new method called LECC-SVET was introduced to obtain current densities closer to the true corrosion conditions using simulated local electrolyte conductivity.
Article
Engineering, Biomedical
Kai Xiang Kuah, Sudesh Wijesinghe, Daniel J. Blackwood
Summary: Limited material transport during the degradation of magnesium implants affects their corrosion. This study replicates the limited material transport in vitro and investigates its influence on the corrosion of magnesium alloys. It is found that the accumulation and competition between chloride and hydroxide ions near the alloy's surface play a role in the corrosion rate.
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
(2023)
Article
Crystallography
Kai Xiang Kuah, Mojtaba Salehi, Zihan Huang, Su Xia Zhang, Hang Li Seet, Mui Ling Sharon Nai, Daniel John Blackwood
Summary: This study investigates the influence of hydroxyapatite and phosphate conversion coatings on the corrosion performance of dense and porous magnesium alloys, and finds that the coating is more effective on the dense magnesium alloy. The microstructure and geometric influence of the porous magnesium alloy affect the effectiveness of the coating application, and limited diffusion within the pore channels leads to differing localized corrosion environments.
Article
Electrochemistry
Ying Wang, Man Fai Ng, Teck Leong Tan, Daniel John Blackwood
Summary: Pitting corrosion is a dangerous form of corrosion that can cause sudden catastrophic failures in engineering systems. The propagation rates of pits depend on the cathodic current available from the oxygen reduction reaction (ORR) on the passive film. Experimental and computational methods were used to investigate the ORR kinetics on FeCr alloys. The results suggest that Cr additions suppress the ORR reaction and play a role in preventing pitting corrosion.
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2023)
Article
Materials Science, Multidisciplinary
Kai Xiang Kuah, Daniel J. Blackwood
Summary: The addition of molybdenum enhances the pitting corrosion resistance in 304L stainless steel, but the exact mechanism is still unclear. One potential explanation is that molybdenum converts sulfide to stable MoS2. However, this study observed the reduction of MoS2 to Mo during the sintering process, contradicting the assumption that sulfide inclusions can be stabilized by forming MoS2. Therefore, the formation of MoS2 cannot explain the improved corrosion resistance in 304L stainless steel with the addition of molybdenum.
NPJ MATERIALS DEGRADATION
(2023)
Article
Materials Science, Multidisciplinary
Kai Xiang Kuah, Mojtaba Salehi, Wee Kit Ong, Hang Li Seet, Mui Ling Sharon Nai, Sudesh Wijesinghe, Daniel J. Blackwood
Summary: The corrosion performance of binder jet additive samples is compared with cast samples in Na2SO4 solution through potentiodynamic polarization. The presence of higher zinc levels in the magnesium matrix and MgO in the microstructure of the binder jet printed alloy results in increases in anodic and cathodic kinetics, respectively. It is suggested that the electron inhomogeneity at the Mg/MgO interface in the binder jet printed alloy is responsible for the catalytic activity of the hydrogen evolution reaction. The removal of MgO inclusions suppresses the cathodic reaction and significantly increases the kinetics, compared to similarly treated cast samples.
NPJ MATERIALS DEGRADATION
(2022)
Article
Chemistry, Multidisciplinary
Yang Gui, Daniel J. Blackwood
Summary: A capacitive deionization cell with symmetric activated carbon electrodes was able to reduce wastewater Pb2+ concentrations below 5 ppm, with a maximum removal efficiency of 98% at an optimized voltage of 1.3 V. Poor reversibility during the first cycle was improved by electrolyte acidification, and subsequent cycles showed good reversibility. It was also found that Na+ ions do not interfere with the removal rate or reversibility of Pb2+ ions, providing new insights for desalination applications.
Article
Materials Science, Biomaterials
Mohammadreza Kasravi, Alireza Yaghoobi, Tahereh Tayebi, Mahsa Hojabri, Abdolkarim Talebi Taheri, Fatemeh Shirzad, Bahram Jambar Nooshin, Radman Mazloomnejad, Armin Ahmadi, Fatemeh A. Tehrani, Ghasem Yazdanpanah, Mohammad Hadi Farjoo, Hassan Niknejad
Summary: As a promising approach in translational medicine, the decellularization of discarded livers to produce bioscaffolds that support recellularization has potential in overcoming the limitations of conventional liver transplantation. In this study, the researchers investigated the use of matrix metalloproteinase (MMP) inhibition to preserve the extracellular matrix (ECM) during liver decellularization. The results demonstrated that the application of an MMP inhibitor significantly improved the preservation of ECM components and mechanical properties of the bioscaffolds, which supported cell viability and function in vitro. The study also confirmed that the MMP inhibition led to the inhibition of MMP2 and MMP9, providing a novel method to enhance ECM preservation during liver decellularization.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Mohammadsadegh Nadimifar, Weiguang Jin, Clara Coll-Satue, Gizem Bor, Paul Joseph Kempen, Ali Akbar Moosavi-Movahedi, Leticia Hosta-Rigau
Summary: This study presents a metal-phenolic self-assembly approach that can prepare nanoparticles fully made of hemoglobin. The nanoparticles exhibit good oxygen binding and releasing capabilities.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jyoti Kumari, Roel Hammink, Jochem Baaij, Frank A. D. T. G. Wagener, Paul H. J. Kouwer
Summary: Fibrosis is the formation of fibrous connective tissue in response to injury, leading to organ dysfunction. A novel hybrid hydrogel combining synthetic polyisocyanide with hyaluronic acid has been developed, showing strong antifibrotic properties.
BIOMATERIALS ADVANCES
(2024)
Letter
Materials Science, Biomaterials
Melissa Machado Rodrigues, Cristian Padilha Fontoura, Charlene Silvestrin Celi Garcia, Sandro Tomaz Martins, Joao Antonio Pegas Henriques, Carlos Alejandro Figueroa, Mariana Roesch Ely, Cesar Aguzzoli
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jessica Polak, David Sachs, Nino Scherrer, Adrian Suess, Huan Liu, Mitchell Levesque, Sabine Werner, Edoardo Mazza, Gaetana Restivo, Mirko Meboldt, Costanza Giampietro
Summary: Human skin equivalents (HSEs) play a crucial role in tissue engineering. This study introduces a 3D-printed culture insert to apply a static radial constraint on HSEs and examines its effects on tissue characteristics. The results show that the diameter of the culture insert significantly influences tissue contraction, fibroblast and matrix organization, keratinocyte differentiation, epidermal stratification, and basement membrane formation. This study provides important insights for the design of skin tissue engineering.
BIOMATERIALS ADVANCES
(2024)
Review
Materials Science, Biomaterials
Shiliang Chen, Tianming Du, Hanbing Zhang, Jing Qi, Yanping Zhang, Yongliang Mu, Aike Qiao
Summary: This paper reviewed the primary methods for improving the overall properties of biodegradable zinc stents. It discussed the mechanical properties, degradation behavior, and biocompatibility of various improvement strategies. Alloying was found to be the most common, simple, and effective method for improving mechanical properties. Deformation processing and surface modification further improved the mechanical properties and biological activity of zinc alloys. Meanwhile, structural design could endow stents with special properties. Manufacturing zinc alloys with excellent properties and exploring their interaction mechanism with the human body are areas for future research.
BIOMATERIALS ADVANCES
(2024)