Article
Chemistry, Multidisciplinary
Weiliang Guo, Ping Zhou, Lei Sun, Hao Ding, Bin Su
Summary: The study utilized microtube electrode (MTE) and microscopy to measure the thickness of ECL layer (TEL) in order to decipher reaction mechanisms. Different systems exhibited varying changes in ECL pattern and TEL, with the catalytic route playing a significant role in these variations.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Electrochemistry
Jing Yu, Hiba Saada, Neso Sojic, Gabriel Loget
Summary: This article investigates the photoinduced electrochemiluminescence of a luminol analog on n-type hematite nanorod arrays, demonstrating its potential applications in bioanalysis and imaging with light-addressable strategies.
ELECTROCHIMICA ACTA
(2021)
Article
Biochemical Research Methods
Rossella Svigelj, Ivan Zuliani, Nicolo Dossi, Rosanna Toniolo
Summary: Cow's milk allergy is a common food allergy in children, and this study developed an aptasensor based on electrochemiluminescence for the quantification of beta-LG in real food matrices. The sensor demonstrated high specificity, good sensitivity, portability, and cost effectiveness.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Yixin Liu, Yuanyuan Yao, Beibei Yang, Yan-Jun Liu, Baohong Liu
Summary: Cell migration and metabolic changes in confined microenvironments play a crucial role in cancer metastasis. In this study, an electrochemiluminescence sensing platform was developed for in-situ monitoring of cell-secreted lactate in highly confined microenvironments, providing a feasible approach for metabolite analysis in such settings.
CHINESE CHEMICAL LETTERS
(2022)
Article
Chemistry, Multidisciplinary
Zhengxing Gong, Jing Luo, Xinrong Shao, Xu Sun, Huan Wang, Dan Wu, Dawei Fan, Yuyang Li, Qin Wei, Huangxian Ju
Summary: A novel quenching electrochemiluminescence (ECL) immunosensor was developed for the trace detection of neuron-specific enolase (NSE). By doping CdS with Zn2+ to form a special complex structure, the optical and electrochemical properties of the sensor were significantly improved. Meanwhile, the quenching of ECL signal was effectively achieved by preparing Rh0.6Ru0.4 alloys and loading silver nanoparticles onto its surface. The immunosensor exhibited a wide detection range, good stability, and biocompatibility.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Analytical
Xue Huang, He Li, Mengjiao Hu, Mengyuan Bai, Yemin Guo, Xia Sun
Summary: This work presents a novel and effective electrochemiluminescence aptasensor for rapid detection of atrazine. The aptasensor utilizes the catalytic decomposition of H2O2 by silver nanoparticles to enhance the ECL intensity, allowing for the detection of atrazine concentration.
Article
Chemistry, Analytical
Gengjun Liu, Xiaohan Guan, Binxiao Li, Hong Zhou, Na Kong, Haiyan Wang
Summary: In this study, an ultrasensitive luminol electrochemiluminescence immunosensor was developed using glucose oxidase-decorated hemin-graphene oxide-gold nanoflowers ternary nanocomposites as probes for the detection of prostate specific antigen (PSA). The biosensor exhibited high catalytic activity and achieved selective recognition of the analyte molecules through specific binding. This biosensor showed promising application in the analysis of human serum samples with a wide linear range and good recovery rate.
Article
Polymer Science
Pengchong Hou, Xian Zhang, Qian Lu, Shunwei Chen, Qiang Liu, Congde Qiao, Hui Zhao
Summary: Four polycarbazole derivatives with different alkyl side chains were synthesized and immobilized on an ITO electrode to construct a novel ECL sensor. The increase in degree of polymerization greatly enhanced the ECL signal, while the increase in alkyl side chain length had little effect. The P-3/ITO platform showed high sensitivity and selective detection of Fe3+ with a wide detection range and low detection limit.
Article
Engineering, Environmental
Yemin Guo, Fengzhen Yang, Yao Yao, Jiansen Li, Shuting Cheng, Haowei Dong, Hui Zhang, Yaodong Xiang, Xia Sun
Summary: An ultrasensitive and selective electrochemiluminescence (ECL) aptasensor with Au-tetrahedral aptamer nanostructure (Au-TAN) was developed for acetamiprid detection. By optimizing the pH of the buffer solution, the concentration of H2O2, and the concentration of Au-TAN, a detection limit lower than other sensors was achieved. The weak alkaline environment explored in the experiment further expanded the application range of the sensor, showing high accuracy and sensitivity.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Chemistry, Analytical
Sisi Chen, Yitian Huang, Lihong Gao, Shupei Zhang, Yanjie Chen, Baoshan Zeng, Hong Dai
Summary: Based on the specific interaction between Con A and Glu, a competitive ECL biosensor was developed for ultrasensitive detection of Con A. Excellent nanocomposites with electrocatalytic and photothermal properties were obtained by bonding ZnO QDs to V2C MXene surfaces, which amplified the luminol cathodic emission and accelerated the electron transfer process for synergistic amplified ECL system.
Article
Chemistry, Analytical
Jingwei Shi, Yang Zhang, Peilin Wang, Yixin Nie, Qiang Ma
Summary: A novel ECL sensor was developed to detect miRNA-210 in TNBC patients' serum, utilizing luminous MoS2 nanosheets and biomimetic magnetic vesicles for efficient capture and sensitive detection. This approach achieved sensitive detection in a range from 1 fM to 100 pM with a detection limit of 0.3 fM, showing potential for a wide range of bioanalytical applications.
Article
Chemistry, Analytical
Yipeng Li, Jun Liu, Peng Pan, Shaoze Zhi, Yangyang Qi, Jie He, Zhengchun Yang, Haoze Ye
Summary: In this study, a portable electrochemiluminescence (ECL) imaging system based on Raspberry Pi was developed for the instant detection of melamine. The system used a lithium battery as the excitation source and Ru (bpy)32+/TPA as the reaction system. A homemade 3D-printed black box served as the reaction chamber for the ECL reaction. ECL images were captured by a camera and classified by the MobileNet model. The experimental results demonstrated highly sensitive detection of melamine, making this system a promising tool for instant detection.
MICROCHEMICAL JOURNAL
(2023)
Article
Biophysics
Hongkun Li, Qianqian Cai, Jianru Wang, Guifen Jie
Summary: This study presents a unique FeMoOv nanozyme-bipolar electrode (NM-BPE) electrochemiluminescence (ECL) biosensing and imaging platform for sensitive detection of hydrogen peroxide (H2O2) and prostate specific antigen (PSA). The anode of the BPE is equipped with ECL reagent bipyridine ruthenium (Ru(bpy)32+), while the cathode is equipped with Fe-doped molybdenum oxide/Au nanoparticles (FeMoOv/AuNPs) with excellent peroxidase (POD) and catalase (CAT)-like activity. By utilizing the efficient enzyme catalysis effect of FeMoOv/AuNPs, the electron transfer rate in the NM-BPE system is accelerated, enhancing the ECL signal of Ru(bpy)32+. Based on this principle, the study achieved sensitive detection of H2O2 and designed a sandwich immunosensor for highly sensitive detection of PSA using FeMoOv/AuNPs as recognition probe. A unique mobile phone ECL imaging system was also developed for PSA assay, providing a portable imaging sensing device for bioassays. This study not only broadened the applications of nanozymes, but also pioneered the new joint ECL research technique of bipolar electrode and ECL imaging in bioassays, showing great application prospect for multiple detection of proteins, nucleic acids, and cancer cells.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Chemistry, Analytical
Tong Shao, Xiaolei Song, Peng Li, Shihao Sun, Dingzhong Wang, Wei Wei
Summary: A novel electrochemiluminescence (ECL) sensor was developed by combining Zr-based metal organic framework (ZrMOF) and branched polyethylenimine (BPEI)-coated Ru(dcbpy)32+ through electrostatic interaction for nicotine analysis. The constructed ECL sensor displayed ultrasensitive determination of nicotine with a detection limit of 1.9 x 10-12 M, three orders lower than previously reported ECL results and 4-5 orders lower than other types of methods. This method provides a new approach for building efficient ECL system with greatly improved ECL sensitivity for nicotine detection.
Article
Biophysics
Hongkun Li, Qianqian Cai, Yali Xue, Guifen Jie
Summary: A unique dual-mode biosensor based on hydrogen-bonded organic frameworks (HOF-101) was constructed for ultrasensitive detection and imaging of oxytetracycline (OXY), using polydopamine nanoparticles (PDAs) as quencher. PDAs, with good biocompatibility and light absorption ability, were introduced onto the surface of HOF-101 to quench its electro-chemiluminescence (ECL) and photoelectrochemical (PEC) signals, achieving ultrasensitive detection of OXY.
BIOSENSORS & BIOELECTRONICS
(2024)
Article
Engineering, Electrical & Electronic
Sylvain Feruglio, Thierry Courcier, Olivier Tsiakaka, Armine Karami, Annick Alexandre-Gauthier, Olivier Romain, Vincent Aimez, Paul G. Charette, Patrick Pittet, Guo-Neng Lu
IEEE SENSORS JOURNAL
(2016)
Article
Radiology, Nuclear Medicine & Medical Imaging
P. Guiral, J. Ribouton, P. Jalade, R. Wang, J. -M. Galvan, G. -N. Lu, P. Pittet, A. Rivoire, L. Gindraux
Article
Nuclear Science & Technology
Pierrick Guiral, Ruoxi Wang, Jean-Marc Galvan, Guo-Neng Lu, Patrice Jalade, Julien Ribouton, Patrick Pittet
RADIATION MEASUREMENTS
(2017)
Review
Engineering, Biomedical
P. Pittet, P. Jalade, L. Gindraux, P. Guiral, R. Wang, J. -M. Galvan, G. -N. Lu
Article
Instruments & Instrumentation
M. M. Vignetti, F. Calmon, P. Pittet, G. Pares, R. Cellier, L. Quiquerez, T. Chaves de Albuquerque, E. Bechetoille, E. Testa, J. -P. Lopez, D. Dauvergne, A. Savoy-Navarro
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT
(2018)
Article
Engineering, Electrical & Electronic
Quentin Lavigne, Nicolas Terrier, Guillaume Noetinger, Duc-Duy Tran, Simon Kulifaj, Pascal Kleimann, Patrick Pittet, Bruno Berge
SENSORS AND ACTUATORS A-PHYSICAL
(2019)
Article
Radiology, Nuclear Medicine & Medical Imaging
P. Pittet, J. Esteves, J. -M. Galvan, G. -N. Lu, F. Blanc, G. Haefeli, P. Hopchev, S. Rit, L. Desbat, J. Ribouton, P. Jalade
Article
Engineering, Electrical & Electronic
Tulio Chaves de Albuquerque, Dylan Issartel, Raphael Clerc, Patrick Pittet, Remy Cellier, Dominique Golanski, Sebastien Jouan, Andreia Cathelin, Francis Calmon
SOLID-STATE ELECTRONICS
(2020)
Article
Engineering, Electrical & Electronic
Thais Luana Vidal de Negreiros da Silva, Pascal Kleimann, Patrick Pittet, Guo-Neng Lu
SOLID-STATE ELECTRONICS
(2020)
Article
Engineering, Electrical & Electronic
Thais Luana Vidal de Negreiros da Silva, Patrick Pittet, Guo-Neng Lu
Summary: A physically-based model of the Buried Multiple Junction (BMJ) detector has been established considering the device operation in reach-through conditions. The model successfully explains the detector's breakdown voltage shift behavior and changes in spectral responses based on bias voltages, providing accurate computations of dark currents and spectral responses. The comparison of the model with TCAD simulations shows good agreement, validating the proposed model.
IEEE SENSORS JOURNAL
(2021)
Proceedings Paper
Computer Science, Interdisciplinary Applications
Pierrick Guiral, Patrick Pittet, Yannick Grondin, Patrice Jalade, Jean-Marc Galvan, Guo-Neng Lu, Laurent Desbat, Philippe Cinquin
MEDINFO 2019: HEALTH AND WELLBEING E-NETWORKS FOR ALL
(2019)
Proceedings Paper
Nuclear Science & Technology
J. Esteves, P. Pittet, J. Ribouton, P. Jalade, J-M Galvan, F. Blanc, G. Haefeli, P. Hopchev, G-N Lu
2019 IEEE NUCLEAR SCIENCE SYMPOSIUM AND MEDICAL IMAGING CONFERENCE (NSS/MIC)
(2019)
Proceedings Paper
Engineering, Electrical & Electronic
T. Chaves de Albuquerque, D. Issartel, R. Clerc, P. Pittet, R. Cellier, W. Uhring, A. Cathelin, F. Calmon
49TH EUROPEAN SOLID-STATE DEVICE RESEARCH CONFERENCE (ESSDERC 2019)
(2019)
Proceedings Paper
Engineering, Multidisciplinary
Pierrick Guiral, Guo-Neng Lu, Patrick Pittet, Jean-Marc Galvan, Vincent Gelly, Patrice Jalade
PROCEEDINGS OF THE 30TH ANNIVERSARY EUROSENSORS CONFERENCE - EUROSENSORS 2016
(2016)
Proceedings Paper
Engineering, Electrical & Electronic
M. M. Vignetti, F. Calmon, R. Cellier, P. Pittet, L. Quiquerez, A. Savoy-Navarro
2015 IEEE 13TH INTERNATIONAL NEW CIRCUITS AND SYSTEMS CONFERENCE (NEWCAS)
(2015)
Article
Materials Science, Biomaterials
Mohammadreza Kasravi, Alireza Yaghoobi, Tahereh Tayebi, Mahsa Hojabri, Abdolkarim Talebi Taheri, Fatemeh Shirzad, Bahram Jambar Nooshin, Radman Mazloomnejad, Armin Ahmadi, Fatemeh A. Tehrani, Ghasem Yazdanpanah, Mohammad Hadi Farjoo, Hassan Niknejad
Summary: As a promising approach in translational medicine, the decellularization of discarded livers to produce bioscaffolds that support recellularization has potential in overcoming the limitations of conventional liver transplantation. In this study, the researchers investigated the use of matrix metalloproteinase (MMP) inhibition to preserve the extracellular matrix (ECM) during liver decellularization. The results demonstrated that the application of an MMP inhibitor significantly improved the preservation of ECM components and mechanical properties of the bioscaffolds, which supported cell viability and function in vitro. The study also confirmed that the MMP inhibition led to the inhibition of MMP2 and MMP9, providing a novel method to enhance ECM preservation during liver decellularization.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Mohammadsadegh Nadimifar, Weiguang Jin, Clara Coll-Satue, Gizem Bor, Paul Joseph Kempen, Ali Akbar Moosavi-Movahedi, Leticia Hosta-Rigau
Summary: This study presents a metal-phenolic self-assembly approach that can prepare nanoparticles fully made of hemoglobin. The nanoparticles exhibit good oxygen binding and releasing capabilities.
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jyoti Kumari, Roel Hammink, Jochem Baaij, Frank A. D. T. G. Wagener, Paul H. J. Kouwer
Summary: Fibrosis is the formation of fibrous connective tissue in response to injury, leading to organ dysfunction. A novel hybrid hydrogel combining synthetic polyisocyanide with hyaluronic acid has been developed, showing strong antifibrotic properties.
BIOMATERIALS ADVANCES
(2024)
Letter
Materials Science, Biomaterials
Melissa Machado Rodrigues, Cristian Padilha Fontoura, Charlene Silvestrin Celi Garcia, Sandro Tomaz Martins, Joao Antonio Pegas Henriques, Carlos Alejandro Figueroa, Mariana Roesch Ely, Cesar Aguzzoli
BIOMATERIALS ADVANCES
(2024)
Article
Materials Science, Biomaterials
Jessica Polak, David Sachs, Nino Scherrer, Adrian Suess, Huan Liu, Mitchell Levesque, Sabine Werner, Edoardo Mazza, Gaetana Restivo, Mirko Meboldt, Costanza Giampietro
Summary: Human skin equivalents (HSEs) play a crucial role in tissue engineering. This study introduces a 3D-printed culture insert to apply a static radial constraint on HSEs and examines its effects on tissue characteristics. The results show that the diameter of the culture insert significantly influences tissue contraction, fibroblast and matrix organization, keratinocyte differentiation, epidermal stratification, and basement membrane formation. This study provides important insights for the design of skin tissue engineering.
BIOMATERIALS ADVANCES
(2024)
Review
Materials Science, Biomaterials
Shiliang Chen, Tianming Du, Hanbing Zhang, Jing Qi, Yanping Zhang, Yongliang Mu, Aike Qiao
Summary: This paper reviewed the primary methods for improving the overall properties of biodegradable zinc stents. It discussed the mechanical properties, degradation behavior, and biocompatibility of various improvement strategies. Alloying was found to be the most common, simple, and effective method for improving mechanical properties. Deformation processing and surface modification further improved the mechanical properties and biological activity of zinc alloys. Meanwhile, structural design could endow stents with special properties. Manufacturing zinc alloys with excellent properties and exploring their interaction mechanism with the human body are areas for future research.
BIOMATERIALS ADVANCES
(2024)
