Fucoxanthin: A Marine Carotenoid Exerting Anti-Cancer Effects by Affecting Multiple Mechanisms

Anti-Cancer Mechanism and Possibility of Nano-Suspension Formulation for a Marine Algae Product Fucoxanthin

(2013) Srinivasan Muthuirulappan et al.   Asian Pacific Journal of Cancer Prevention

Marine algal fucoxanthin inhibits the metastatic potential of cancer cells

(2013) Tae-Wook Chung et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Assessment of potential anti-cancer stem cell activity of marine algal compounds using an in vitro mammosphere assay

(2013) Jo-Anne de la Mare et al.   Cancer Cell International

Fucoxanthin Enhances Cisplatin-Induced Cytotoxicity via NFκB-Mediated Pathway and Downregulates DNA Repair Gene Expression in Human Hepatoma HepG2 Cells

(2013) Cheng-Ling Liu et al.   Marine Drugs

Pharmacogenomics of Cytochrome P450 3A4: Recent Progress Toward the “Missing Heritability” Problem

(2013) Kathrin Klein et al.   Frontiers in Genetics

Inhibition of tumor growth in vitro and in vivo by fucoxanthin against melanoma B16F10 cells

(2012) Kil-Nam Kim et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

The consumption of seaweed as a protective factor in the etiology of breast cancer: proof of principle

(2012) Jane Teas et al.   JOURNAL OF APPLIED PHYCOLOGY

Fucoxanthin Attenuates Rifampin-Induced Cytochrome P450 3A4 (CYP3A4) and Multiple Drug Resistance 1 (MDR1) Gene Expression Through Pregnane X Receptor (PXR)-Mediated Pathways in Human Hepatoma HepG2 and Colon Adenocarcinoma LS174T Cells

(2012) Cheng-Ling Liu et al.   Marine Drugs

In Vivo Induction of Apoptosis by Fucoxanthin, a Marine Carotenoid, Associated with Down-Regulating STAT3/EGFR Signaling in Sarcoma 180 (S180) Xenografts-Bearing Mice

(2012) Jun Wang et al.   Marine Drugs

Siphonaxanthin, a marine carotenoid from green algae, effectively induces apoptosis in human leukemia (HL-60) cells

(2011) Ponesakki Ganesan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Pharmacokinetics of fucoxanthinol in human plasma after the oral administration of kombu extract

(2011) Takashi Hashimoto et al.   BRITISH JOURNAL OF NUTRITION

Fucoxanthin, a Marine Carotenoid Present in Brown Seaweeds and Diatoms: Metabolism and Bioactivities Relevant to Human Health

(2011) Juan Peng et al.   Marine Drugs

Role of Bcl-2 family proteins and caspases in the regulation of apoptosis

(2011) Mohammad Shamsul Ola et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Fucoxanthin and its deacetylated product, fucoxanthinol, induce apoptosis of primary effusion lymphomas

(2010) Kei Yamamoto et al.   CANCER LETTERS

Cytochrome P450 3A4 mRNA Is a More Reliable Marker than CYP3A4 Activity for Detecting Pregnane X Receptor-Activated Induction of Drug-Metabolizing Enzymes

(2010) O. A. Fahmi et al.   DRUG METABOLISM AND DISPOSITION

Effects of fucoxanthin on proliferation and apoptosis in human gastric adenocarcinoma MGC-803 cells via JAK/STAT signal pathway

(2010) Rui-xue Yu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Anti-pigmentary activity of fucoxanthin and its influence on skin mRNA expression of melanogenic molecules

(2010) Hiroshi Shimoda et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Fucoxanthin induces apoptosis in human leukemia HL-60 cells through a ROS-mediated Bcl-xL pathway

(2010) Kil-Nam Kim et al.   TOXICOLOGY IN VITRO

Implication of mitogen-activated protein kinase in the induction of G1 cell cycle arrest and gadd45 expression by the carotenoid fucoxanthin in human cancer cells

(2009) Yoshiko Satomi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Inhibition of proliferation of a hepatoma cell line by fucoxanthin in relation to cell cycle arrest and enhanced gap junctional intercellular communication

(2009) Cheng-Ling Liu et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Suppressive effects of the marine carotenoids, fucoxanthin and fucoxanthinol on triglyceride absorption in lymph duct-cannulated rats

(2009) Megumi Matsumoto et al.   EUROPEAN JOURNAL OF NUTRITION

Comparative effects of β-carotene and fucoxanthin on retinol deficiency induced oxidative stress in rats

(2009) R. K. Sangeetha et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Pregnane X Receptor and its Potential Role in Drug Resistance in Cancer Treatment

(2009) Yakun Chen et al.   Recent Patents on Anti-Cancer Drug Discovery

Growth inhibition of human hepatic carcinoma HepG2 cells by fucoxanthin is associated with down-regulation of cyclin D

(2008) Swadesh K. Das et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Low bioavailability of dietary epoxyxanthophylls in humans

(2008) Akira Asai et al.   BRITISH JOURNAL OF NUTRITION

Fucoxanthin restrains oxidative stress induced by retinol deficiency through modulation of Na+Ka+-ATPase and antioxidant enzyme activities in rats

(2008) Sangeetha Ravi Kumar et al.   EUROPEAN JOURNAL OF NUTRITION

Antiadult T-cell leukemia effects of brown algae fucoxanthin and its deacetylated product, fucoxanthinol

(2008) Chie Ishikawa et al.   INTERNATIONAL JOURNAL OF CANCER

Protective effect of fucoxanthin isolated from Sargassum siliquastrum on UV-B induced cell damage

(2008) Soo-Jin Heo et al.   JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY

Comparative evaluation of growth inhibitory effect of stereoisomers of fucoxanthin in human cancer cell lines

(2008) Y. Nakazawa et al.   Journal of Functional Foods

In vitro antioxidant activities of three selected brown seaweeds of India

(2007) S. Kumar Chandini et al.   FOOD CHEMISTRY