Synthesis of Marine Polycyclic Polyethers via Endo-Selective Epoxide-Opening Cascades

Maitotoxin converts the plasmalemmal Ca2+ pump into a Ca2+-permeable nonselective cation channel

(2009) William G. Sinkins et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Functionalized Templates for the Convergent Assembly of Polyethers: Synthesis of the HIJK Rings of Gymnocin A

(2009) Aaron R. Van Dyke et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Epoxide-Opening Cascades in the Synthesis of Polycyclic Polyether Natural Products

(2009) Ivan Vilotijevic et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The development of endo-selective epoxide-opening cascades in water

(2009) Christopher J. Morten et al.   CHEMICAL SOCIETY REVIEWS

Brevisin: An Aberrant Polycyclic Ether Structure from the DinoflagellateKarenia brevisand Its Implications for Polyether Assembly

(2009) Masayuki Satake et al.   JOURNAL OF ORGANIC CHEMISTRY

Stereo- and Regioselective Synthesis of Squalene Tetraepoxide

(2009) Rongbiao Tong et al.   JOURNAL OF ORGANIC CHEMISTRY

Total Synthesis ofent-Dioxepandehydrothyrsiferol via a Bromonium-Initiated Epoxide-Opening Cascade

(2009) Jessica Tanuwidjaja et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

On the Synergism Between H2O and a Tetrahydropyran Template in the Regioselective Cyclization of an Epoxy Alcohol

(2009) Jeffery A. Byers et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Water Overcomes Methyl Group Directing Effects in Epoxide-Opening Cascades

(2009) Christopher J. Morten et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Synthesis of Gambierol

(2009) Hiroki Furuta et al.   ORGANIC LETTERS

Gold(I)-Catalyzed Cascade Cyclization of Allenyl Epoxides

(2009) Michael A. Tarselli et al.   ORGANIC LETTERS

Regiodivergent Ring Opening of Chiral Aziridines

(2009) B. Wu et al.   SCIENCE

New synthetic strategies for the stereocontrolled synthesis of substituted ‘skipped’ diepoxides

(2009) Christopher J. Morten et al.   TETRAHEDRON

Mimicking Biosynthesis: Total Synthesis of the Triterpene Natural Product Abudinol B from a Squalene-like Precursor

(2008) Rongbiao Tong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Continuing Saga of the Marine Polyether Biotoxins

(2008) K. C. Nicolaou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Analysis of Specific Mutants in the Lasalocid Gene Cluster: Evidence for Enzymatic Catalysis of a Disfavoured Polyether Ring Closure

(2008) Luke Smith et al.   CHEMBIOCHEM

Organocatalytic Oxidation. Asymmetric Epoxidation of Olefins Catalyzed by Chiral Ketones and Iminium Salts

(2008) O. Andrea Wong et al.   CHEMICAL REVIEWS

Chemical Synthesis of the GHIJKLMNO Ring System of Maitotoxin

(2008) K. C. Nicolaou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Epoxide Hydrolase Lsd19 for Polyether Formation in the Biosynthesis of Lasalocid A: Direct Experimental Evidence on Polyene-Polyepoxide Hypothesis in Polyether Biosynthesis

(2008) Yoshihiro Shichijo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Diverse Bacterial PKS Sequences Derived From Okadaic Acid-Producing Dinoflagellates

(2008) Roberto Perez et al.   Marine Drugs

Convergent strategies for the total synthesis of polycyclic ether marine metabolites

(2008) Makoto Sasaki et al.   NATURAL PRODUCT REPORTS

Unusually cyclized triterpenes: occurrence, biosynthesis and chemical synthesis

(2008) Victoriano Domingo et al.   NATURAL PRODUCT REPORTS

The biosynthesis of polyketide-derived polycyclic ethers

(2008) Andrew R. Gallimore   NATURAL PRODUCT REPORTS

Brevisamide: An Unprecedented Monocyclic Ether Alkaloid from the DinoflagellateKarenia brevisThat Provides a Potential Model for Ladder-Frame Initiation

(2008) Masayuki Satake et al.   ORGANIC LETTERS

Gambierol, a toxin produced by the dinoflagellate Gambierdiscus toxicus, is a potent blocker of voltage-gated potassium channels

(2008) Eva Cuypers et al.   TOXICON