Sporozoite immunization of human volunteers under chemoprophylaxis induces functional antibodies against pre-erythrocytic stages of Plasmodium falciparum

Model forIn VivoAssessment of Humoral Protection against Malaria Sporozoite Challenge by Passive Transfer of Monoclonal Antibodies and Immune Serum

(2013) Brandon K. Sack et al.   INFECTION AND IMMUNITY

Role of host cell traversal by the malaria sporozoite during liver infection

(2013) Joana Tavares et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Molecular detection and quantification of Plasmodium falciparum-infected human hepatocytes in chimeric immune-deficient mice

(2013) Lander Foquet et al.   MALARIA JOURNAL

Looking under the skin: the first steps in malarial infection and immunity

(2013) Robert Ménard et al.   NATURE REVIEWS MICROBIOLOGY

Four-Year Efficacy of RTS,S/AS01E and Its Interaction with Malaria Exposure

(2013) Ally Olotu et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Relationship between RTS,S Vaccine-Induced Antibodies, CD4+ T Cell Responses and Protection against Plasmodium falciparum Infection

(2013) Michael T. White et al.   PLoS One

Protection against malaria after immunization by chloroquine prophylaxis and sporozoites is mediated by preerythrocytic immunity

(2013) E. M. Bijker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protection Against Malaria by Intravenous Immunization with a Nonreplicating Sporozoite Vaccine

(2013) R. A. Seder et al.   SCIENCE

First-in-human evaluation of genetically attenuated Plasmodium falciparum sporozoites administered by bite of Anopheles mosquitoes to adult volunteers

(2013) Michele Spring et al.   VACCINE

Development of a quantitative flow cytometry-based assay to assess infection by Plasmodium falciparum sporozoites

(2012) Alexis Kaushansky et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

ReducedPlasmodium bergheisporozoite liver load associates with low protective efficacy after intradermal immunization

(2012) K. NGANOU-MAKAMDOP et al.   PARASITE IMMUNOLOGY

Real-time PCR-based assay to quantify the relative amount of human and mouse tissue present in tumor xenografts

(2011) Sergio Y Alcoser et al.   BMC BIOTECHNOLOGY

Long-term protection against malaria after experimental sporozoite inoculation: an open-label follow-up study

(2011) Meta Roestenberg et al.   LANCET

Sterile Protective Immunity to Malaria is Associated with a Panel of NovelP. falciparumAntigens

(2011) Angela Trieu et al.   MOLECULAR & CELLULAR PROTEOMICS

Longevity and Composition of Cellular Immune Responses Following Experimental Plasmodium falciparum Malaria Infection in Humans

(2011) Anne C. Teirlinck et al.   PLoS Pathogens

Comparison of Plasmodium berghei challenge models for the evaluation of pre-erythrocytic malaria vaccines and their effect on perceived vaccine efficacy

(2010) Wolfgang W Leitner et al.   MALARIA JOURNAL

The RTS,S malaria vaccine

(2010) Sofia Casares et al.   VACCINE

Acquired Immunity to Malaria

(2009) D. L. Doolan et al.   CLINICAL MICROBIOLOGY REVIEWS

Randomized, Double‐Blind, Phase 2a Trial of Falciparum Malaria Vaccines RTS,S/AS01B and RTS,S/AS02A in Malaria‐Naive Adults: Safety, Efficacy, and Immunologic Associates of Protection

(2009) Kent E. Kester et al.   JOURNAL OF INFECTIOUS DISEASES

Protection against a Malaria Challenge by Sporozoite Inoculation

(2009) Meta Roestenberg et al.   NEW ENGLAND JOURNAL OF MEDICINE

Recombinant Liver Stage Antigen-1 (LSA-1) formulated with AS01 or AS02 is safe, elicits high titer antibody and induces IFN-γ/IL-2 CD4+ T cells but does not protect against experimental Plasmodium falciparum infection

(2009) James F. Cummings et al.   VACCINE

Kinetics of Mosquito-Injected Plasmodium Sporozoites in Mice: Fewer Sporozoites Are Injected into Sporozoite-Immunized Mice

(2009) Chahnaz Kebaier et al.   PLoS Pathogens

Host Cell Traversal Is Important for Progression of the Malaria Parasite through the Dermis to the Liver

(2008) Rogerio Amino et al.   Cell Host & Microbe

Gene Disruption of Plasmodium falciparum p52 Results in Attenuation of Malaria Liver Stage Development in Cultured Primary Human Hepatocytes

(2008) Ben C. L. van Schaijk et al.   PLoS One

Profiling humoral immune responses to P. falciparum infection with protein microarrays

(2008) Denise L. Doolan et al.   PROTEOMICS

Phase 2a trial of 0, 1, and 3 month and 0, 7, and 28 day immunization schedules of malaria vaccine RTS,S/AS02 in malaria-naïve adults at the Walter Reed Army Institute of Research

(2008) Kent E. Kester et al.   VACCINE