Article
Optics
Zihan Zang, Zhi Li, Yi Luo, Yanjun Han, Hongtao Li, Xuanyi Liu, H. Y. Fu
Summary: This study combines all-optical encoders with wavelength-division multiplexing devices to achieve fast and efficient acquisition of light detection and ranging (LiDAR) technology. By implementing parallel detection and fast spectral scanning, the fastest single-pixel LiDAR to date is achieved, with scalability to increase detection speed. This approach breaks the limitations of current ultrafast single-pixel LiDAR and opens up new possibilities for ultrafast-frame-rate imaging systems.
Article
Neurosciences
Alina Scholz, Robin Etzel, Markus W. May, Mirsad Mahmutovic, Qiyuan Tian, Gabriel Ramos-Llorden, Chiara Maffei, Berkin Bilgic, Thomas Witzel, Jason P. Stockmann, Choukri Mekkaoui, Lawrence L. Wald, Susie Yi Huang, Anastasia Yendiki, Boris Keil
Summary: In this study, a 48-channel ex vivo whole brain array coil was designed and constructed for high-resolution and high b-value diffusion-weighted imaging on a 3T Connectome scanner. The coil showed significantly increased SNR in the peripheral cortex and center regions compared to a 64-channel head coil designed for in vivo use. Additionally, the coil reduced noise amplification in highly parallel imaging, allowing for higher acceleration factors.
Article
Radiology, Nuclear Medicine & Medical Imaging
Chaoping Zhang, Stefan Klein, Alexandra Cristobal-Huerta, Juan A. Hernandez-Tamames, Dirk H. J. Poot
Summary: APIR4EMC improves the quality of multi-contrast imaging by reducing artifacts and noise amplification compared to single contrast reconstruction with GRAPPA. In phantom acquisitions, APIR4EMC substantially decreased noise amplification and RMSE, reducing artifacts. In in-vivo experiments, 1mm³ isotropic 3D images with various contrasts were acquired in as little as 7.5 minutes with an acceleration factor of 9.
MAGNETIC RESONANCE IMAGING
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Anpreet Ghotra, Heather L. Kosakowski, Atsushi Takahashi, Robin Etzel, Markus W. May, Alina Scholz, Andreas Jansen, Lawrence L. Wald, Nancy Kanwisher, Rebecca Saxe, Boris Keil
Summary: An adaptive 32-channel array coil was developed to improve compliance and performance of infant head fMRI scans. By utilizing an adjustable head coil and infant-friendly design, the coil showed increased signal-to-noise ratio and imaging capabilities, suitable for fMRI studies in awake infants.
MAGNETIC RESONANCE IN MEDICINE
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Robin Etzel, Choukri Mekkaoui, Ekaterina S. Ivshina, Timothy G. Reese, David E. Sosnovik, Sam-Luca J. D. Hansen, Anpreet Ghotra, Nicolas Kutscha, Chaimaa Chemlali, Lawrence L. Wald, Andreas H. Mahnken, Boris Keil
Summary: The study compared three 64-channel cardiac coil array configurations and found that the C-Dense array with non-uniform loop density demonstrated the best performance in terms of SNR and SMS encoding power in cardiac imaging. Optimized non-uniform loop density and size play a positive role in enabling highly accelerated SMS cardiac MRI.
MAGNETIC RESONANCE IN MEDICINE
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Hayato Tomita, Yuki Deguchi, Hirofumi Fukuchi, Atsuko Fujikawa, Yoshiko Kurihara, Kaoru Kitsukawa, Hidefumi Mimura, Yasuyuki Kobayashi
Summary: This study compared the acquisition time and image quality of CS and PI in oral T2-weighted imaging. The results showed that CSPI-T2WI had a shorter acquisition time and higher fat/muscle contrast ratio compared to PI-T2WI, with no significant differences in overall image quality, artifacts, and visualization of anatomical structures.
EUROPEAN RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yanbo Chen, Yong Li, Wenzhou Liu, Zhihui Wang, Jiajie Li, Chen Chen, Gang Zeng, Jun Shen, Weidong Song
Summary: This study shows that using the surface microscopy coil (SMC) for preoperative assessment improves the accuracy of measurement of osteochondral lesions of the talus (OLTs) compared with conventional coil MRI. The traditional MRI has low reliability and tends to overestimate or underestimate the size of the lesions. The SMC provides more accurate diameter measurements and has a higher concordance rate with surgical assessment compared to ASC MRI.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2023)
Article
Optics
Wenchang Lai, Guozhong Lei, Qi Meng, Yanxing Ma, Wenda Cui, Dongfeng Shi, Hao Liu, Yan Wang, Kai Han
Summary: This article proposes the use of a Fermat spiral laser array as an illumination source in ghost imaging. The array successfully achieves high-quality ghost imaging through experimental demonstration and the combination with a compressive sensing reconstruction algorithm. This method has great potential for application in remote sensing.
Article
Optics
Wenchang Lai, Guozhong Lei, Qi Meng, Yanxing Ma, Wenda Cui, Dongfeng Shi, Hao Liu, Yan Wang, Kai Han
Summary: A novel laser array is proposed as an illumination source for ghost imaging. Experimental demonstration shows that the method can achieve high-quality ghost imaging. This technology is expected to be applied in the field of remote sensing.
Article
Multidisciplinary Sciences
Stefan Herz, Maria R. Stefanescu, David Lohr, Patrick Vogel, Aleksander Kosmala, Maxim Terekhov, Andreas M. Weng, Jan-Peter Grunz, Thorsten A. Bley, Laura M. Schreiber
Summary: This study investigates the effects of B-1-shimming and RF parallel transmission on the visualization and quantification of coronary artery stenosis using 7 Tesla MRI. The results demonstrate that B-1-shimming and pTX significantly improve image homogeneity and provide more accurate MR image analysis.
Article
Multidisciplinary Sciences
Maxim Terekhov, Ibrahim A. Elabyad, Laura M. Schreiber
Summary: In the development of novel multiple-element transmit-receive arrays for ultra-high magnetic field strength cardiac MRI, finding default driving phases for individual coil elements is crucial. A robust technique has been proposed in this study to optimize B-1 homogeneity in the default setup, leading to drastic reduction in computation time and superior homogeneity characteristics compared to traditional methods.
Article
Radiology, Nuclear Medicine & Medical Imaging
Paul D. Griffiths, Mariasavina Severino, Deborah Jarvis, Laura Mandefield, Cecilia Parazzini, Lorenzo Pinelli, Marco Di Maurizio, Fabio Triulzi, Elisa Scola, Giorgio Conte, Giovanni Palumbo, Maurilio Genovese, Andrea Rossi, Renzo Guerrini, Andrea Righini
Summary: The study included 64 foetuses with cortical formation abnormalities (CFA) who underwent two in utero magnetic resonance (iuMR) exams, with 62% showing consistent CFA description between the two studies. In 38% of cases, there was a category change, including cases without CFA initially detected, changes in laterality/symmetry, and re-classification within the same group. Brain abnormalities other than CFA were present in around half of the cases on both first and second studies. Prognosis was predicted to have changed in 8% of cases based on the second study, with all indicating a worse prognosis.
EUROPEAN RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Feifei Qu, Taotao Sun, Yongsheng Chen, Brijesh Kumar Yadav, Ling Jiang, Zhaoxia Qian, E. Mark Haacke
Summary: The study utilized STAGE imaging to estimate tissue properties in the fetal brain, finding that the ratios of T-1app and PDapp in different regions varied, indicating the potential utility of STAGE imaging for assessing fetal brain properties.
EUROPEAN RADIOLOGY
(2021)
Article
Engineering, Electrical & Electronic
Busra Kahraman-Agir, Korkut Yegin, Esin Ozturk-Isik
Summary: The study designed a wearable and elastic surface coil using conductive and stretchable textile for MRI of breast, demonstrating its effectiveness on phantoms with varying sizes. By calculating the SNR, researchers found that the 6mm resolution plate hole diameter was clearly discernible in axial MR images, indicating the coil's validity. The elastic coil has the potential to enhance clinical applications of MRI and improve patient comfort.
IEEE MICROWAVE AND WIRELESS COMPONENTS LETTERS
(2021)
Article
Obstetrics & Gynecology
N. M. DeSouza
Summary: Cytological screening and HPV testing have improved early diagnosis of cervical cancer in young women. MRI imaging helps define the extent of the disease within the cervix and aids in deciding on fertility-sparing surgical options. High spatial resolution images are achieved with T2-weighted and DW MRI, providing accurate information for optimal oncological outcomes and reduced obstetric risks.
BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Daniel Polak, Daniel Nicolas Splitthoff, Bryan Clifford, Wei-Ching Lo, Susie Y. Huang, John Conklin, Lawrence L. Wald, Kawin Setsompop, Stephen Cauley
Summary: The SAMER technique utilizes accelerated scout scans and novel sequence reordering to achieve clinically acceptable motion estimation and reconstruction time. It demonstrates high accuracy and stability in both simulation and in vivo evaluation, enabling high-quality imaging and retrospective motion estimation.
MAGNETIC RESONANCE IN MEDICINE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Sai Abitha Srinivas, Stephen F. Cauley, Jason P. Stockmann, Charlotte R. Sappo, Christopher E. Vaughn, Lawrence L. Wald, William A. Grissom, Clarissa Z. Cooley
Summary: The EDITER method introduced in this study is an external sensor-based method to remove image artifacts caused by external interference sources in portable MRI systems. Experimental results demonstrate the effectiveness of the method in reducing EMI in phantom and in vivo imaging experiments, as well as increasing image signal-to-noise ratio.
MAGNETIC RESONANCE IN MEDICINE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Mathias Davids, Bastien Guerin, Lawrence L. Wald
Summary: Representing PNS information on a Huygens' surface extended the approach's ability to assess PNS across body positions and models and test the robustness of PNS optimization in gradient design.
MAGNETIC RESONANCE IN MEDICINE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Bijaya Thapa, Azma Mareyam, Jason Stockmann, Bernhard Strasser, Boris Keil, Philipp Hoecht, Stefan Carp, Xianqi Li, Zhe Wang, Yulin Chang, Jorg Dietrich, Erik Uhlmann, Daniel P. Cahill, Tracy Batchelor, Lawrence Wald, Ovidiu C. Andronesi
Summary: This study aimed to develop an absolute quantification method for whole-brain MRSI in glioma patients, successfully achieving accurate metabolite quantification in healthy volunteers through the integration of ERETIC with receive arrays. However, there was a discrepancy between ERETIC and internal water quantification methods in glioma patients.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jason P. Stockmann, Nicolas S. Arango, Thomas Witzel, Azma Mareyam, Charlotte Sappo, Jiazheng Zhou, Lucas Jenkins, Lincoln Craven-Brightman, Eugene Milshteyn, Mathias Davids, W. Scott Hoge, Monika Sliwiak, Shahin Nasr, Boris Keil, Elfar Adalsteinsson, Bastien Guerin, Jacob K. White, Kawin Setsompop, Jonathan R. Polimeni, Lawrence L. Wald
Summary: Adding Delta B-0 shim capability to a 31-channel 7T receive array can significantly improve 7T brain B-0 homogeneity without sacrificing the array's radiofrequency performance. Global and slice-optimized shimming provide 11% and 40% improvements respectively compared to baseline second-order spherical harmonic shimming.
MAGNETIC RESONANCE IN MEDICINE
(2022)
Article
Clinical Neurology
Maria G. Garcia-Gomar, Aleksandar Videnovic, Kavita Singh, Matthew Stauder, Laura D. Lewis, Lawrence L. Wald, Bruce R. Rosen, Marta Bianciardi
Summary: This study investigated structural connectivity changes in iRBD patients using an in vivo probabilistic brainstem nuclei atlas and 7 Tesla MRI. The results revealed impaired structural connectivity in 14 brainstem nuclei in iRBD patients, including connections between REM-on nuclei and areas responsible for REM sleep muscle atonia.
MOVEMENT DISORDERS
(2022)
Article
Neurosciences
Fuyixue Wang, Zijing Dong, Timothy G. Reese, Bruce Rosen, Lawrence L. Wald, Kawin Setsompop
Summary: 3D-EPTI is a novel approach that increases the acceleration capacity of MRI sampling and provides high acquisition efficiency for multi-parametric MRI. It exploits the spatiotemporal correlation of MRI data to achieve faster sampling and enables high-resolution multi-parametric imaging for studying complex brain processes.
Article
Radiology, Nuclear Medicine & Medical Imaging
Valerie Klein, Jaume Coll-Font, Livia Vendramini, Donald Straney, Mathias Davids, Natalie G. Ferris, Lothar R. Schad, David E. Sosnovik, Christopher T. Nguyen, Lawrence L. Wald, Bastien Guerin
Summary: The study measured cardiac magnetostimulation thresholds in pigs and found that the IEC cardiac safety limit may be overly conservative for the investigated stimulus duration.
MAGNETIC RESONANCE IN MEDICINE
(2022)
Article
Neurosciences
Qiuyun Fan, Cornelius Eichner, Maryam Afzali, Lars Mueller, Chantal M. W. Tax, Mathias Davids, Mirsad Mahmutovic, Boris Keil, Berkin Bilgic, Kawin Setsompop, Hong-Hsi Lee, Qiyuan Tian, Chiara Maffei, Gabriel Ramos-Llorden, Aapo Nummenmaa, Thomas Witzel, Anastasia Yendiki, Yi-Qiao Song, Chu-Chung Huang, Ching-Po Lin, Nikolaus Weiskopf, Alfred Anwander, Derek K. Jones, Bruce R. Rosen, Lawrence L. Wald, Susie Y. Huang
Summary: In the past decade, tremendous efforts have been made to advance cutting-edge MRI technology in order to map the structural connectivity in the living human brain. This review article summarizes the technical developments in using the Connectom scanner for large-scale and scientific studies of the human brain, and discusses the scientific impact of the Connectom MRI scanner.
Article
Clinical Neurology
M. Lang, A. Tabari, D. Polak, J. Ford, B. Clifford, W. -C. Lo, K. Manzoor, D. N. Splitthoff, L. L. Wald, O. Rapalino, P. Schaefer, J. Conklin, S. Cauley, S. Y. Huang
Summary: The SAMER framework was evaluated in 97 clinical brain MRI examinations and found to significantly improve motion artifacts, especially in cases with moderate or severe motion.
AMERICAN JOURNAL OF NEURORADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Valerie Klein, Mathias Davids, Livia Vendramini, Natalie G. Ferris, Lothar R. Schad, David E. Sosnovik, Christopher T. Nguyen, Lawrence L. Wald, Bastien Guerin
Summary: Coupled electromagnetic-electrophysiological modeling in detailed body and heart models can predict cardiac stimulation thresholds, which can lead to more detailed threshold estimates in humans. Experimental and predicted thresholds in eight pigs showed good agreement. This modeling approach can be applied to study cardiac stimulation thresholds in humans for various conditions.
MAGNETIC RESONANCE IN MEDICINE
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Mathias Davids, Peter Dietz, Gudrun Ruyters, Manuela Roesler, Valerie Klein, Bastien Guerin, David A. Feinberg, Lawrence L. Wald
Summary: By analyzing various aspects of head gradient design using a detailed peripheral nerve stimulation (PNS) model, we have successfully designed a new high-performance asymmetric head gradient coil to raise PNS thresholds and maximize usable image-encoding performance.
MAGNETIC RESONANCE IN MEDICINE
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Filiz Yetisir, Esra Abaci Turk, Elfar Adalsteinsson, Lawrence Leroy Wald, Patricia Ellen Grant
Summary: This study evaluates the imaging performance of two-channel RF-shimming for fetal MRI at 3 T using four different local specific absorption rate (SAR) management strategies. The results show that the use of subject-specific models with local SAR limits based on maximum CP mode SAR levels in the pregnant population can safely and significantly improve the transmit field inside the fetus.
MAGNETIC RESONANCE IN MEDICINE
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Ehsan Kazemivalipour, Lawrence L. Wald, Bastien Guerin
Summary: This study models the performance of parallel transmission arrays with different channel numbers for brain imaging and compares them with birdcage coils and cylindrical pTx coils. The results show that helmet designs outperform cylindrical pTx arrays in terms of local specific absorption rate and flip-angle uniformity, especially for non-transverse slice excitations.
MAGNETIC RESONANCE IN MEDICINE
(2023)
Article
Engineering, Biomedical
Erica E. Mason, Eli Mattingly, Konstantin Herb, Stephen F. Cauley, Monika Sliwiak, John M. Drago, Matthias Graeser, Emiri T. Mandeville, Joseph B. Mandeville, Lawrence L. Wald
Summary: This study evaluates magnetic particle imaging (MPI) as a new functional imaging modality by mapping the cerebral blood volume (CBV) response. The results show that MPI has higher sensitivity than functional magnetic resonance imaging (fMRI) in detecting changes in CBV.
PHYSICS IN MEDICINE AND BIOLOGY
(2023)