Article
Environmental Sciences
Mark Annunziato, Muhamed N. H. Eeza, Narmin Bashirova, Ariel Lawson, Joerg Matysik, Daniel Benetti, Martin Grosell, John D. Stieglitz, A. Alia, John P. Berry
Summary: Brevetoxins are neurotoxins associated with harmful algal blooms, with research on toxicity mechanisms and biomarkers aiding in understanding environmental impacts. Metabolic profiling using HRMAS NMR on zebrafish embryos exposed to PbTx-2 revealed acute embryotoxicity in both zebrafish and mahi-mahi at environmentally relevant concentrations. Metabolomics studies provided insight into potential biomarkers and toxicity pathways at environmentally relevant toxin levels.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Oncology
Mohammad Alwahsh, Robert Knitsch, Rosemarie Marchan, Joerg Lambert, Christian Hoerner, Xiaonan Zhang, Berthold Schalke, De-Hyung Lee, Elena Bulut, Thomas Graeter, German Ott, Katrin S. Kurz, Gerhard Preissler, Sebastian Schoelch, Joviana Farhat, Zhihan Yao, Carsten Sticht, Philipp Stroebel, Roland Hergenroeder, Alexander Marx, Djeda Belharazem
Summary: This study is the first metabolomics investigation on thymic epithelial tumors, which identified differential metabolic profiles among different subtypes and predicted activated metabolic pathways. These findings provide new insights for the treatment of aggressive thymomas and thymic carcinomas.
Review
Food Science & Technology
Abdul-Hamid M. Emwas, Nahla Al-Rifai, Kacper Szczepski, Shuruq Alsuhaymi, Saleh Rayyan, Hanan Almahasheer, Mariusz Jaremko, Lorraine Brennan, Joanna Izabela Lachowicz
Summary: The relationship between health and nutrition is closely linked, with poor nutrition potentially leading to various metabolic diseases. Metabolomics, as an emerging field of science, has broad research applications and potential for further advancement.
Article
Biochemical Research Methods
Manuela Grimaldi, Carmen Marino, Michela Buonocore, Angelo Santoro, Eduardo Sommella, Fabrizio Merciai, Emanuela Salviati, Arianna De Rosa, Tommaso Nuzzo, Francesco Errico, Pietro Campiglia, Alessandro Usiello, Anna Maria D'Ursi
Summary: Originally believed to be present only in bacteria and invertebrates, D-amino acids have also been found in mammalian tissues. Depletion of D-Asp in the brain has been shown to influence amino acid pathways and metabolites related to brain development and function.
JOURNAL OF PROTEOME RESEARCH
(2021)
Article
Chemistry, Analytical
Monica Bastawrous, Oliver Gruschke, Ronald Soong, Amy Jenne, Dieter Gross, Falko Busse, Ben Nashman, Andressa Lacerda, Andre J. Simpson
Summary: Nuclear magnetic resonance (NMR) spectroscopy plays a vital role in medical and environmental metabolic research, but studying smaller biological samples is challenging. Microcoil NMR shows great potential for analyzing small samples and improving sensitivity. The study found that the Helmholtz microcoil outperforms the planar coil in analyzing complex biological samples.
ANALYTICAL CHEMISTRY
(2022)
Article
Food Science & Technology
Maria-Eleni Dimitrakopoulou, Konstantina Matzarapi, Styliani Chasapi, Apostolos Vantarakis, Georgios A. Spyroulias
Summary: Non-targeted H-1 NMR fingerprinting combined with multivariate statistical analyses were used to classify Greek currants based on their geographical origins effectively. Differences in metabolites allowed for clear classification of currants from different regions. Composition variances in carbohydrates, amino acids, and organic acids were found to be sufficient for geographical discrimination of currants.
JOURNAL OF FOOD SCIENCE
(2021)
Article
Biochemistry & Molecular Biology
Qing Kong, Jinping Gu, Ruohan Lu, Caihua Huang, Lili Chen, Weifeng Wu, Donghai Lin
Summary: In this study, metabolomic analysis of cardiac tissues was conducted to investigate the metabolic changes in different pathological stages of viral myocarditis. The results revealed distinct metabolic differences between the pathological groups and normal controls, and identified impaired metabolic pathways and potential cardiac biomarkers associated with these pathological stages.
Article
Food Science & Technology
Friedemann Fluegge, Tim Kerkow, Paulina Kowalski, Josephine Bornhoft, Eva Seemann, Marina Creydt, Burkhard Schuetze, Ulrich L. Guenther
Summary: Culinary herbs and spices are becoming more popular food products, especially in a time when people are more conscious about the quality of their food. However, ensuring the authenticity of spices is challenging due to complex and long supply chains and unknown sources. A recent report by the EU Joint Research Centre identified oregano as one of the most vulnerable spices to adulteration. In this study, next generation sequencing and NMR spectroscopy were used to identify oregano species and quantify adulterations.
Article
Food Science & Technology
Oscar Daniel Rangel-Huerta, Lada Ivanova, Silvio Uhlig, Morten Sivertsvik, Izumi Sone, Estefania Noriega Fernandez, Christiane Kruse Faeste
Summary: Through rigorous experimentation, it was found that although no significant differences were observed between treatment groups during the storage period, spinach leaves treated with PAW were found to be rich in polyphenolic antioxidants and healthy fats, indicating that PAW contributes to enhanced stress resistance and antioxidant capacity in the sample, ultimately delaying the senescence of spinach leaves.
Review
Food Science & Technology
Pavel A. Solovyev, Carsten Fauhl-Hassek, Janet Riedl, Susanne Esslinger, Luana Bontempo, Federica Camin
Summary: Wine authentication is crucial for identifying malpractice and fraud, using various physical and chemical analytical techniques. The emerging method of H-1 NMR spectroscopy has gained attention in wine analysis for its simplicity and speed in sample preparation, although it lacks official recognition.
COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY
(2021)
Article
Biochemistry & Molecular Biology
Kara M. Edwards, Aishwarya Badiger, Dennis R. Heldman, Matthias S. Klein
Summary: This study investigates the impact of storage temperature and time on the concentration of key metabolites in milk, providing insights into the factors affecting milk stability. Different metabolites exhibit varying responses to storage time and temperature, with potential implications for real-time shelf-life monitoring and reduction of milk waste.
Review
Biophysics
Leo L. Cheng
Summary: This article provides a history of the discovery and recent developments of high-resolution magic angle spinning (HRMAS) NMR, a technique used for intact biological material analysis. HRMAS NMR metabolomics studies have been applied in various fields such as human disease states, plant and food analysis, and cell structure studies. The article also discusses the potential applications of HRMAS NMR in future biomedical investigations.
NMR IN BIOMEDICINE
(2023)
Article
Food Science & Technology
Lin Zhao, Chieng Ning Poh, Jiaying Wu, Xue Zhao, Yun He, Hongshun Yang
Summary: This study investigated the metabolic responses of Escherichia coli biofilms to the combined stresses of ultrasound and low concentration acidic electrolysed water. The findings showed that ultrasound disrupted nucleotide metabolism in E. coli cells within biofilms, while low concentration acidic electrolysed water treatment led to increased amino acid contents and decreased carbohydrate contents. Adaptive strategies like glutamate decarboxylase system and mixed acid fermentation were activated to different extents under combined treatment.
INNOVATIVE FOOD SCIENCE & EMERGING TECHNOLOGIES
(2022)
Article
Agriculture, Multidisciplinary
Thorsten Mix, Jasmin Janneschuetz, Rami Ludwig, Julia Eichbaum, Markus Fischer, Thomas Hackl
Summary: In this study, different truffle species were successfully identified using analytical methods and chemometric models. The results showed that even visually similar black truffles can be distinguished, and the most expensive truffle can be differentiated from other white truffles. Potential markers were also discovered.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Polymer Science
Luis M. Araque, Claudio J. Perez, Antonia Infantes-Molina, Enrique Rodriguez-Castellon, Guillermo J. Copello, Juan M. Lazaro-Martinez
Summary: Two responsive PEI hydrogels (P1.5E and P2E) with different cross-linking degrees were synthesized using a click reaction and without organic solvents. The hydrogel's swelling and rheological behavior were dependent on the cross-linking degree, and the hydrogels showed stimuli-responsive behavior to pH or ionic strength changes. The hydrogels also exhibited adsorption capacity for methyl orange (MO) dye and Cu2+ ions, with P1.5E showing higher sorption capacities. Germination experiments with lettuce seeds confirmed that the hydrogels did not release toxic molecules.
JOURNAL OF APPLIED POLYMER SCIENCE
(2023)
Review
Food Science & Technology
Mena Ritota, Pamela Manzi
FOOD ANALYTICAL METHODS
(2018)
Article
Chemistry, Multidisciplinary
Mena Ritota, Maria Mattera, Maria Gabriella Di Costanzo, Pamela Manzi
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY
(2018)
Review
Chemistry, Analytical
Mena Ritota, Maria Gabriella Di Costanzo, Maria Mattera, Pamela Manzi
JOURNAL OF ANALYTICAL METHODS IN CHEMISTRY
(2017)
Article
Biochemistry & Molecular Biology
Alja Margon, Claudio Mondini, Massimiliano Valentini, Mena Ritota, Liviana Leita
CHEMICAL SPECIATION AND BIOAVAILABILITY
(2013)
Article
Agriculture, Multidisciplinary
Daniela Pacifico, Lorena Casciani, Mena Ritota, Giuseppe Mandolino, Chiara Onofri, Anna Moschella, Bruno Parisi, Caterina Cafiero, Massimiliano Valentin
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2013)
Article
Agriculture, Multidisciplinary
Mena Ritota, Lorena Casciani, Massimiliano Valentini
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2013)
Article
Food Science & Technology
Mena Ritota, Lorena Casciani, Sebastiana Failla, Massimiliano Valentini
Review
Green & Sustainable Science & Technology
Mena Ritota, Pamela Manzi
Review
Agriculture, Dairy & Animal Science
Mena Ritota, Pamela Manzi
Article
Biochemistry & Molecular Biology
Pamela Manzi, Maria Gabriella Di Costanzo, Mena Ritota
Summary: This study evaluated the zinc content of different Italian cheeses, with cow cheeses showing the highest zinc content, followed by sheep cheeses, and cheeses from mixed milk. The great variability in zinc content among the samples is influenced by factors such as feeding system, species, and cheese-making process. Most samples made a significant contribution to the zinc Daily Reference Intake, set at 10 mg/day by EU.
Article
Biochemistry & Molecular Biology
Mena Ritota, Raffaella Comitato, Pamela Manzi
Summary: Saffron is a widely consumed spice with various therapeutic and anticancer effects. This study characterized the bioactive compounds in cheeses made with saffron and investigated their antiproliferative effects on different cellular lines. The results showed that crocins were present in all cheese samples, and the antiproliferative effect varied depending on the cheese making process and the milk species used.
Article
Agriculture, Dairy & Animal Science
Federico Paggio, Mena Ritota, Maria Gabriella Di Costanzo, Stefania Barzaghi, Lucia Monti, Alessandro Ulrici, Pamela Manzi
Summary: We investigated the feasibility of increasing the storage temperature of raw milk for Provolone Valpadana cheesemaking and identified optimal conditions for a pre-maturation process. Principal Component Analysis (PCA) was used to analyze the effects of different storage conditions on the chemical, nutritional, and technological characteristics of the raw milk. Four different thermal storage cycles were studied, and it was found that a two-phase thermal cycle at mild refrigeration conditions could be beneficial for milk pre-maturation without compromising its quality.
JOURNAL OF DAIRY RESEARCH
(2023)
Review
Agriculture, Multidisciplinary
Mena Ritota, Pamela Manzi
Summary: The increasing consumer demands for healthier and more sustainable foods has pushed the food industry in the constant research of new foods, new functional ingredients and bioactive compounds, whose production can be considered as far as sustainable. In this sense, application of the edible mushrooms has attracted the attention of industries because of their good nutritional quality, simple and economically affordable growth, taste, flavor, and textural properties, as well as the presence of bioactive compounds with positive effects on human health. This review aims for providing the more recent information about Pleurotus incorporation into foods, with a critical vision looking forward to the future, without forgetting overview of the more recent literature about Pleurotus spp. nutritional value and their healthy promoting compounds.
AIMS AGRICULTURE AND FOOD
(2023)
Article
Biochemistry & Molecular Biology
Mena Ritota, Pamela Manzi
Proceedings Paper
Plant Sciences
M. Ritota, S. Cozzolino, S. Marconi, P. Sequi, M. Valentini, F. Marini
XXVIII INTERNATIONAL HORTICULTURAL CONGRESS ON SCIENCE AND HORTICULTURE FOR PEOPLE (IHC2010): INTERNATIONAL SYMPOSIUM ON PLANT PHYSIOLOGY FROM CELL TO FRUIT PRODUCTION SYSTEM
(2012)
