Article
Critical Care Medicine
Nina A. Thomas, Ralph Ward, Nichole T. Tanner, Alana M. Rojewski, Benjamin Toll, Mulugeta Gebregziabher, Gerard A. Silvestri
Summary: In a secondary analysis of the NLST arm of the American College of Radiology Imaging Network, it was found that only a quarter of lung cancer screening patients received pharmacologic therapy for smoking cessation, and those who did receive treatment were more likely to attempt to quit. Patients with high nicotine dependence benefited most from dual pharmacologic therapy.
Review
Oncology
Saverio Caini, Marco Del Riccio, Virginia Vettori, Vieri Scotti, Chiara Martinoli, Sara Raimondi, Giulio Cammarata, Domenico Palli, Marco Banini, Giovanna Masala, Sara Gandini
Summary: This study summarized the current scientific evidence on the impact of quitting smoking at or around diagnosis on the survival of lung cancer (LC) patients. The results showed that quitting smoking at or around diagnosis is significantly associated with improved overall survival among LC patients, regardless of the histological type of LC. Therefore, treating physicians should educate patients about the benefits of quitting smoking and provide them with the necessary support for smoking cessation.
JOURNAL OF THORACIC ONCOLOGY
(2022)
Review
Substance Abuse
Yuvaraj Krishnamoorthy, Venmathi Elangovan, Sathish Rajaa
Summary: This study aimed to identify the best non-pharmacological therapies for tobacco cessation in India. The results showed that e-Health intervention had the highest tobacco cessation rate, followed by group counseling and individual counseling. However, more high-quality studies are needed to provide conclusive evidence for the adoption of these interventions in national health programs in India.
NICOTINE & TOBACCO RESEARCH
(2023)
Article
Public, Environmental & Occupational Health
Rachael L. Murray, Emma O'Dowd
Summary: Despite the decrease in smoking rates since 2000, smoking remains a significant risk factor for premature mortality and lung cancer. Continuing to smoke after a lung cancer diagnosis is associated with increased mortality and tumor recurrence. A recent meta-analysis indicates that quitting smoking around the time of lung cancer diagnosis is associated with improved survival.
LANCET PUBLIC HEALTH
(2023)
Article
Oncology
Randi M. Williams, Marisa Cordon, Ellie Eyestone, Laney Smith, George Luta, Brady J. McKee, Shawn M. Regis, David B. Abrams, Raymond S. Niaura, Cassandra A. Stanton, Vicky Parikh, Kathryn L. Taylor
Summary: This study found that lung cancer screening could serve as a teachable moment for smoking cessation, with individuals who were extremely worried about lung cancer being more motivated to quit smoking and more ready to quit within the next 30 days.
Article
Oncology
Richard S. Matulewicz, Jeffrey C. Bassett, Lorna Kwan, Scott E. Sherman, William J. McCarthy, Christopher S. Seigal, John L. Gore
Summary: A strategy that includes provider education and a customized clinical decision support tool can facilitate provider use of evidence-based practices for tobacco cessation in a urology clinic.
Article
Cardiac & Cardiovascular Systems
Aaron M. Delman, Kevin M. Turner, Koffi Wima, Victoria E. Simon, Sandra L. Starnes, Shimul A. Shah, Robert M. Van Haren
Summary: This study assessed the impact of smoking status on postoperative morbidity and mortality among lung cancer patients. The results showed that current smokers had similar rates of mortality and major morbidity as prior smokers. The findings suggest that smoking cessation requirements should not delay or prevent surgical intervention for lung cancer patients.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2022)
Article
Critical Care Medicine
Kristie L. Foley, Emily V. Dressler, Kathryn E. Weaver, Erin L. Sutfin, David P. Miller Jr, Christina Bellinger, Carol Kittel, Rebecca J. Stone, W. Jeffrey Petty, Stephanie R. Land, John G. Spangler, Glenn J. Lesser, Caroline Chiles
Summary: This study explores how to implement effective tobacco use treatment during lung cancer screening. Although there was a significant reduction in tobacco use over time, there was no difference between the intervention and control groups.
Article
Oncology
Jacqueline V. Aredo, Sophia J. Luo, Rebecca M. Gardner, Nilotpal Sanyal, Eunji Choi, Thomas P. Hickey, Thomas L. Riley, Wen-Yi Huang, Allison W. Kurian, Ann N. Leung, Lynne R. Wilkens, Hilary A. Robbins, Elio Riboli, Rudolf Kaaks, Anne Tjonneland, Roel C. H. Vermeulen, Salvatore Panico, Loic Le Marchand, Christopher I. Amos, Rayjean J. Hung, Neal D. Freedman, Mattias Johansson, Iona Cheng, Heather A. Wakelee, Summer S. Han
Summary: The study revealed that smoking is a risk factor for second primary lung cancer (SPLC), and smoking cessation may reduce the risk of SPLC. Additionally, individuals who meet the U.S. Preventive Services Task Force's criteria at the diagnosis of initial primary lung cancer also have an increased risk of developing SPLC.
JOURNAL OF THORACIC ONCOLOGY
(2021)
Review
Nursing
Siqi Zhang, Maria Jose Duaso
Summary: This meta-ethnographic synthesis study aimed to gain insights into the experiences of nurses who smoke and understand the impact of those experiences on their delivery of smoking cessation interventions. The results indicated that nurses who smoke often experience guilt and stigma, and workplace policies play a significant role in creating cognitive dissonance. Nurses use various coping mechanisms to deal with dissonance, including rationalizing smoking benefits, hiding their smoking behavior, and denying smoking risks. Some nurses express willingness to quit smoking and engage in smoking cessation interventions, showing positive aspirations in coping with dissonance.
JOURNAL OF ADVANCED NURSING
(2021)
Article
Critical Care Medicine
Amanda M. Palmer, Alana M. Rojewski, Li-shiun Chen, Lisa M. Fucito, Panagis Galiatsatos, Hasmeena Kathuria, Stephanie R. Land, Glen D. Morgan, Alex T. Ramsey, Kimber P. Richter, Xiaozhong Wen, Benjamin A. Toll
Summary: Tobacco treatment programs should be integrated into medical systems, with medical providers having the opportunity to initiate smoking cessation treatment with patients. However, barriers may hinder the development and implementation of these programs.
Article
Public, Environmental & Occupational Health
Aline F. Fares, Yao Li, Mei Jiang, M. Catherine Brown, Andrew C. L. Lam, Reenika Aggarwal, Sabine Schmid, Natasha B. Leighl, Frances A. Shepherd, Zhichao Wang, Nancy Diao, Angela S. Wenzlaff, Juntao Xie, Takashi Kohno, Neil E. Caporaso, Curtis Harris, Hongxia Ma, Matthew J. Barnett, Leticia Ferro Leal, G. Fernandez-Tardon, Manica Perez-Rios, Michael P. A. Davies, Fiona Taylor, Ben Schoettker, Paul Brennan, David Zaridze, Ivana Holcatova, Jolanta Lissowska, Beata Swiatkowska, Dana Mates, Milan Savic, Hermann Brenner, Angeline Andrew, Angela Cox, John K. Field, Alberto Ruano-Ravina, Sanjay S. Shete, Adonina Tardon, Ying Wang, Loic Le Marchand, Rui Manuel Reis, Matthew B. Schabath, Chu Chen, Hongbing Shen, Brid M. Ryan, Maria Teresa Landi, Kouya Shiraishi, Jie Zhang, Ann G. Schwartz, Ming S. Tsao, David C. Christiani, Ping Yang, Rayjean J. Hung, Wei Xu, Geoffrey Liu
Summary: This large-scale study conducted in multiple countries and regions worldwide found that the duration of smoking abstinence is associated with overall survival in patients with NSCLC, even when diagnosed at a later lung-cancer screening visit.
LANCET PUBLIC HEALTH
(2023)
Article
Cardiac & Cardiovascular Systems
Su-Min Jeong, Jung Eun Yoo, Junhee Park, Wonyoung Jung, Kyu Na Lee, Kyungdo Han, Cheol Min Lee, Ki-Woong Nam, Seung-Pyo Lee, Dong Wook Shin
Summary: This study examined the association between smoking behavior change and the risk of cardiovascular disease incidence and mortality in patients with type 2 diabetes mellitus (T2DM). The results showed that quitting smoking was associated with a significantly decreased risk of myocardial infarction and ischemic stroke, whereas reducing smoking was not significantly associated with these risks.
CARDIOVASCULAR DIABETOLOGY
(2023)
Article
Critical Care Medicine
Jolie Shen, Kristina Crothers, Erin K. Kross, Kaylee Petersen, Anne C. Melzer, Matthew Triplette
Summary: The study found that provision of smoking cessation resources during shared decision-making encounters for lung cancer screening was moderate overall, but lower in patients with more comorbidities or when not conducted by the primary care provider or specialist. Interventions are needed to improve smoking cessation counseling and resource utilization during LCS encounters.
Review
Pharmacology & Pharmacy
Xue Shang, Kangle Guo, E. Fenfen, Xinxin Deng, Yongsheng Wang, Ziyi Wang, Yanan Wu, Meng Xu, Chaoqun Yang, Xiuxia Li, Kehu Yang
Summary: This study conducted a network meta-analysis and found that pharmacological interventions can be effective in smoking cessation. Varenicline and combined treatments with nicotine replacement therapy and mecamylamine showed the most promising results.
FRONTIERS IN PHARMACOLOGY
(2022)
Review
Toxicology
Peter N. Lee, Marc W. Fariss
ARCHIVES OF TOXICOLOGY
(2017)
Review
Toxicology
Peter N. Lee, Jan S. Hamling
INHALATION TOXICOLOGY
(2016)
Article
Medicine, Legal
Peter N. Lee, John R. Gosney
REGULATORY TOXICOLOGY AND PHARMACOLOGY
(2016)
Article
Medicine, Legal
Peter N. Lee, Barbara A. Forey, Katharine J. Coombs, Peter J. Lipowicz, Scott Appleton
REGULATORY TOXICOLOGY AND PHARMACOLOGY
(2016)
Article
Medicine, Legal
Peter N. Lee, Alison J. Thornton, Janette S. Hamling
REGULATORY TOXICOLOGY AND PHARMACOLOGY
(2016)
Article
Neurosciences
Peter N. Lee, Alison J. Thornton, Barbara A. Forey, Jan S. Hamling
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2017)
Article
Medicine, Legal
Peter N. Lee, John S. Fry, Janette S. Hamling
REGULATORY TOXICOLOGY AND PHARMACOLOGY
(2017)
Article
Medicine, Legal
Peter N. Lee, Alison J. Thornton
REGULATORY TOXICOLOGY AND PHARMACOLOGY
(2017)
Article
Medicine, Legal
Peter N. Lee, John S. Fry, John F. Hamling, Zheng Sponsiello-Wang, Gizelle Baker, Rolf Weitkunat
REGULATORY TOXICOLOGY AND PHARMACOLOGY
(2017)
Article
Neurosciences
Peter N. Lee, Alison J. Thornton, Barbara A. Forey, Jan S. Hamling
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2017)
Review
Toxicology
Peter N. Lee
INHALATION TOXICOLOGY
(2018)
Letter
Oncology
Peter Lee, John Fry
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2021)
Article
Toxicology
Peter N. Lee, John S. Fry, Stanley Gilliland, Preston Campbell, Andrew R. Joyce
Summary: Recent estimates suggest that substantial reductions in deaths and life-years lost can be achieved through replacing cigarettes with e-cigarettes, even under pessimistic assumptions. Results varied most for X and F among the parameters considered, indicating the importance of these factors in impacting outcomes.
ARCHIVES OF TOXICOLOGY
(2022)
Article
Health Care Sciences & Services
Smilja Djurdjevic, Peter N. Lee, Rolf Weitkunat, Zheng Sponsiello-Wang, Frank Ludicke, Gizelle Baker
Article
Medicine, Legal
Fiona Sewell, Ian Ragan, Graham Horgan, David Andrew, Thomas Holmes, Irene Manou, Boris P. Mueller, Tim Rowan, Barbara G. Schmitt, Marco Corvaro
Summary: There are currently three test guidelines for acute oral toxicity studies, but the subjectivity of one guideline may be hindering its wider use. In order to address this, the NC3Rs and EPAA collaborated to analyze historical data and provide recommendations on the recognition of 'evident toxicity'.
REGULATORY TOXICOLOGY AND PHARMACOLOGY
(2024)
Article
Medicine, Legal
Michael DeVito, Bas Bokkers, Majorie B. M. van Duursen, Karin van Ede, Mark Feeley, Elsa Antunes Fernandes Gaspar, Laurie Haws, Sean Kennedy, Richard E. Peterson, Ron Hoogenboom, Keiko Nohara, Kim Petersen, Cynthia Rider, Martin Rose, Stephen Safe, Dieter Schrenk, Matthew W. Wheeler, Daniele S. Wikoff, Bin Zhao, Martin van den Berg
Summary: In October 2022, the World Health Organization reevaluated the toxic equivalency factors (TEFs) for chlorinated dioxin-like compounds in a panel convened in Lisbon. This effort utilized an updated database, Bayesian dose response modeling, and meta-analysis to derive Best-Estimate TEFs. Applying these new TEFs may result in lower total toxic equivalents for dioxin-like chemicals.
REGULATORY TOXICOLOGY AND PHARMACOLOGY
(2024)