Article
Agriculture, Dairy & Animal Science
Bartlomiej Maria Jaskowski, Hartwig Bostedt, Marek Gehrke, Jedrzej Maria Jaskowski
Summary: The study shows that recipients with a cavitary corpus luteum have higher progesterone levels and pregnancy rates during embryo transfer. Therefore, the presence of a cavity inside the corpus luteum should not be a reason to exclude recipients from embryo transfer.
Review
Agriculture, Dairy & Animal Science
Massimo Zerani, Angela Polisca, Cristiano Boiti, Margherita Maranesi
Summary: Corpora lutea are temporary endocrine structures that secrete progesterone, essential for a healthy pregnancy. Research using the pseudopregnant rabbit model has shed light on the multifactorial mechanisms regulating CL lifespan, providing valuable insights for overcoming reproductive challenges in mammalian species.
Article
Cell Biology
Ali Mohammed Pitia, Itaru Minagawa, Yasuyuki Abe, Keiichiro Kizaki, Koh-ichi Hamano, Hiroshi Sasada, Kazuyoshi Hashizume, Tetsuya Kohsaka
Summary: This study investigates the function of INSL3 in pregnant goats, showing that the corpus luteum acts as both a source and target of INSL3 while extra-ovarian reproductive organs also serve as targets. Expression levels of INSL3 and RXFP2 peak in middle pregnancy in the corpus luteum, while RXFP2 expression levels in extra-ovarian reproductive organs vary among different organs and remain relatively stable during pregnancy. These findings provide evidence of an active intra- and extra-ovarian INSL3 hormone-receptor system operating during pregnancy in goats.
CELL AND TISSUE RESEARCH
(2021)
Review
Agriculture, Dairy & Animal Science
Dody Houston Billhaq, Seunghyung Lee
Summary: This review discusses the role of the RAS protein in the formation and regression of the corpus luteum in the ovary, highlighting its regulation of cell survival, proliferation, and differentiation through various signaling pathways. The complex molecular events in the ovarian microenvironment, such as angiogenesis and apoptosis, are also emphasized. Further research is needed to better understand how the RAS family impacts the biological events of the corpus luteum in the ovary.
Article
Agriculture, Dairy & Animal Science
S. G. Umana Sedo, C. C. Figueiredo, T. D. Gonzalez, G. A. Duarte, M. B. Ugarte Marin, C. A. Crawford, K. G. Pohler, R. C. Chebel, T. R. Bilby, R. S. Bisinotto
Summary: The objective of this study was to evaluate the effects of two analogs of PGF(2 alpha), cloprostenol and dinoprost, as well as the effects of one injection versus two injections on luteolysis, follicle diameter, hormonal concentrations, and time to ovulation in dairy heifers. The results showed that cloprostenol induced luteolysis faster compared to dinoprost, but treatment did not affect the time to ovulation.
JOURNAL OF DAIRY SCIENCE
(2022)
Article
Agriculture, Dairy & Animal Science
R. S. Bisinotto, E. S. Ribeiro, L. F. Greco, D. Taylor-Rodriguez, A. D. Ealy, H. Ayres, F. S. Lima, N. Martinez, W. W. Thatcher, J. E. P. Santos
Summary: This study evaluated the effects of follicular wave and progesterone concentration on growth of the ovulatory follicle, conceptus elongation, uterine IFN-tau concentration, and transcriptome of conceptus and endometrium in pregnant cows. The results indicated that progesterone concentration had an impact on the growth of ovulatory follicle, but overall had minimal effects on the conceptus and endometrium transcriptome.
JOURNAL OF DAIRY SCIENCE
(2022)
Article
Veterinary Sciences
Yanni Jia, Lu Liu, Suhua Gong, Haijing Li, Xinyan Zhang, Ruixue Zhang, Aihua Wang, Yaping Jin, Pengfei Lin
Summary: This study investigated the expression and regulation of lncRNA Hand2os1 in the ovaries. It was found that Hand2os1 was specifically detected in luteal cells and may regulate progesterone secretion by affecting the key rate-limiting enzyme StAR, potentially impacting pregnancy maintenance.
VETERINARY SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Piotr Kaczynski, Monika Baryla, Ewelina Goryszewska, Agnieszka Waclawik
Summary: Intrauterine infusions of E2 can alter the expression of genes involved in CL function, potentially regulating DNA methylation as a physiological mechanism controlling luteal gene expression.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Veterinary Sciences
Samer M. Daghash, Noha A. E. Yasin, Elshymaa A. Abdelnaby, Ibrahim A. Emam, Ayman Tolba, Yara S. Abouelela
Summary: This study compares the growth and development of the corpus luteum in pregnant and non-pregnant domestic buffalos from days 5 to 40 after ovulation and explores the correlation between luteal vascularity and progesterone and nitric oxide levels.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Agriculture, Dairy & Animal Science
Cecily Bishop, Vimal Selvaraj, David H. Townson, Joy L. Pate, Milo C. Wiltbank
Summary: The corpus luteum (CL) forms from the cellular remnants of the follicle and produces progesterone required for successful pregnancy. The CL and the embryo have a symbiotic relationship, both relying on each other for survival. The Northeast Multistate Project has contributed to our understanding of the regulation and function of the CL in cattle, providing valuable insights for improving fertility.
JOURNAL OF ANIMAL SCIENCE
(2022)
Article
Biotechnology & Applied Microbiology
Jaya Bharati, N. H. Mohan, Satish Kumar, Jayashree Gogoi, Sai Kumar, Bosco Jose, Meeti Punetha, Sanjib Borah, Amit Kumar, Mihir Sarkar
Summary: RNA-Seq was used to identify differentially expressed genes (DEGs) in porcine corpus luteum (CL) during different physiological stages, revealing significant enrichment of gene functions in early, mid, and late stages. Apoptosis was most active in the regressed stage. Pathway analysis indicated lipid metabolism, translation, immune, and endocrine system pathways were associated with CL function. Gene network analysis identified novel hub genes AR, FOS, CDKN1A potentially regulating CL physiology.
Article
Agriculture, Dairy & Animal Science
Liliana Rossetto, Maria Florencia Gallelli, Marcelo Alfredo Aba, Marcelo Horacio Miragaya, Carolina Paula Bianchi
Summary: The study aimed to investigate the effect of early administration of progesterone after ovulation on corpus luteum lifespan in llamas. Female llamas were induced to ovulate and divided into two groups: the treated group received progesterone treatment, while the control group did not. Plasma progesterone concentration and ultrasonographies were monitored throughout the study. The results showed that early progesterone administration affected corpus luteum function in llamas.
ANIMAL REPRODUCTION SCIENCE
(2023)
Article
Reproductive Biology
Haolin Li, Xiaomeng Pei, Hao Yu, Wei Wang, Dagan Mao
Summary: This study investigated the effects of APN/AdipoRon on autophagy and apoptosis in goat luteal cells, and found that autophagy and apoptosis play important roles in the structural regression of goat corpus luteum.
Article
Agriculture, Dairy & Animal Science
Thiago O. Cunha, Leah R. Statz, Rafael R. Domingues, Joao Paulo N. Andrade, Milo C. Wiltbank, Joao Paulo N. Martins
Summary: The objective of this study was to investigate the effects of inducing accessory corpus luteum on follicular and luteal dynamics in lactating Holstein cows. The results showed that inducing accessory corpus luteum not only altered the dynamics of follicles and corpus luteum but also deferred and prolonged the process of luteolysis.
JOURNAL OF DAIRY SCIENCE
(2022)
Article
Agriculture, Dairy & Animal Science
Sarah N. Carr, Benjamin R. Crites, Joy L. Pate, Camilla H. K. Hughes, James C. Matthews, Phillip J. Bridges
Summary: In regions with selenium (Se) deficient soils, supplementing this mineral to the diet of forage-grazing cattle is important. The form of Se supplemented can affect the expression of mRNA encoding selenoproteins in the corpus luteum, leading to changes in progesterone levels. The increase in progesterone appears to be due to increased cholesterol availability by the corpus luteum, not by an increase in the expression of key steroidogenic enzymes.
