期刊
LUPUS
卷 19, 期 2, 页码 119-129出版社
SAGE PUBLICATIONS LTD
DOI: 10.1177/0961203309350755
关键词
systemic lupus erythematosus; male; sex differences; clinical feature; pathogenesis
类别
资金
- National Natural Sciences Foundation of China [30671946]
Although males with systemic lupus erythematosus (SLE) represent 4-22% of all SLE patients, it may not be appropriate that these cases should be subordinated to females with SLE in terms of most health-related issues. Over the past few decades, some distinctive features of male lupus have been observed with regard to genetic and environmental aspects of sex differences, clinical features, and outcome. In addition, recent insights into sex disparities in this disease have brought forth a few plausible and novel pathogenetic hypotheses. This review discusses these findings and sex disparities in SLE that appear to be especially noteworthy and pertinent to our understanding of male SLE. Lupus (2010) 19, 119-129.
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