Article
Chemistry, Physical
Muhammad Adnan, Haidi D. Fiedler, Javed Ali, Muhammad Idrees
Summary: The interaction between pyrene and Fe3+, Cu2+, Cr3+, Ni2+, Pb2+ was studied in 0.02 mol L-1 SDS. All studied heavy metal ions reduced the fluorescence intensity of pyrene, although the level of quenching varied. The quenching of pyrene by heavy metal ions was fitted to the Stern-Volmer equation. The Stern-Volmer constants (K-SV) were obtained, indicating the level of quenching and the sensitivity of the method. The method of pyrene fluorescence quenching by heavy metal ions is a fruitful approach for their determination in environmental samples.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Spectroscopy
Haitham K. R. Al-Sharifi, Ani Deepthi
Summary: Mechanistic studies were conducted on the fluorescence quenching of 2-(2-chloro-12-oxoindolo[2,1-b]quinazolin-6(12H)-ylidene) malononitrile (2CTMA) with aniline in solvent mixtures of acetonitrile and 1,4-dioxane at room temperature, using steady-state and time-resolved methods. It was determined that both dynamic and static quenching processes play a role in the bimolecular quenching reactions, as confirmed by the sphere of action static quenching model and finite sink approximation model.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Chemistry, Analytical
Svetlana A. Mescheryakova, Ivan S. Matlakhov, Pavel D. Strokin, Daniil D. Drozd, Irina Yu. Goryacheva, Olga A. Goryacheva
Summary: Doxorubicin (DOX) is a commonly used anti-tumor drug in chemotherapy, but it has high cardio-, neuro- and cytotoxicity. Therefore, continuous monitoring of DOX concentrations in biofluids and tissues is important. This study demonstrates the capabilities of analytical nanosensors based on the quenching of fluorescence of alloyed CdZnSeS/ZnS quantum dots (QDs) for operative DOX detection. Optimized turn-off fluorescence nanosensors were developed for direct DOX determination in undiluted human plasma.
Article
Environmental Sciences
Vrushali Vinayak Kadam, Raj Mohan Balakrishnan, Jagadeeshbabu Ponnan Ettiyappan
Summary: The study demonstrated the successful synthesis of beta-cyclodextrin-functionalized zinc oxide quantum dots for selective detection of BPA, showing a good linear correlation between fluorescence intensity and BPA concentration under optimal conditions with a low detection limit below the toxic limits in aquatic biota. The fluorescence-based detection of BPA is attributed to the electron transfer mechanism, as explained in scientific literature.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Chemistry, Multidisciplinary
Amal A. A. El-Masry, Abdallah M. M. Zeid
Summary: Acriflavine is a versatile drug with antibacterial, antiviral, antimalarial, and antifungal activities. Its native fluorescence is exploited as a probe for pharmaceutical and biological compound analysis. In this study, acriflavine was used as a fluorescent probe for the first time to analyze the acidic drug aceclofenac. Aceclofenac forms an ion-pair complex with acriflavine at pH 8.5, resulting in partial fluorescence quenching. The proposed method showed excellent greenness and was successfully used for the analysis of aceclofenac in its dosage forms.
Article
Biochemical Research Methods
Bidisha Ghosh, Shubham Roy, Souravi Bardhan, Dhananjoy Mondal, Ishita Saha, Saheli Ghosh, Ruma Basu, Parimal Karmakar, Kaustuv Das, Sukhen Das
Summary: This article reports the fluorometric detection of toxic hexavalent chromium in wastewater and living cells using in-situ grown carbon quantum dots in a goethite nano-matrix. The selective and sensitive chromium sensor shows great potential for determining chromium contamination levels in various water samples, and its sensing mechanism has been evaluated using theoretical models. This research opens new avenues for wastewater monitoring and biomedical applications.
JOURNAL OF FLUORESCENCE
(2022)
Article
Spectroscopy
Mioara Murariu, Lenuta Stroea
Summary: New fluorescent polymeric sensors containing in situ photogenerated gold nanoparticles (Au NPs) and fluorescein-based copolymers are reported. They are tested as efficient fluorescent chemosensors for the sensitive detection of toxic divalent metal ions. The best results are recorded for uranyl (4 x 10-6 M) and copper ions (16 x 10-6 M), respectively. The investigated hybrid materials have lower detection limits and the fluorescence quenching mainly occurs by a dynamic process.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Materials Science, Multidisciplinary
Sonali Mehra, Abhishek K. Chauhan, Shreya Dodeja, Pankaj Kumar, Lalit Goswami, Govind Gupta, A. K. Srivastava, Shailesh Narain Sharma
Summary: This article synthesizes MAPbI3, MAPbICl2, and MAPbIClBr perovskites by one-step and two-step spin-coating methods and investigates their structural and optoelectronic properties. The charge transfer and energy transfer characteristics of perovskite nano crystals passivated by N, N-DMF dissolved in MEH-PPV polymer are also studied. The results show that MAPbI3 perovskite exhibits effective photoluminescence quenching, while energy transfer dominates in degraded composite materials.
Article
Biochemical Research Methods
Muhammad Idrees, Abdul Salam, Munsif Khan
Summary: The interactions between a group of selected phenols (picric acid, p-Nitrophenol, m-Nitrophenol, o-Nitrophenol, and phenol) and the fluorescent probe carbazole in a micellar system of CTAB were studied. The optimal concentration of CTAB for maximum quenching of carbazole was determined for each studied phenol. The quenching of carbazole was observed in both CTAB concentrations, with lower CTAB concentration resulting in higher quenching. The sensitivity of the method, determined by Stern-Volmer constants (K-sv), followed the order picric acid > phenol > m-Nitrophenol > p-Nitrophenol > o-Nitrophenol. The detection threshold (DT) and quantification threshold (QT) were observed in the ranges of 1.76 x 10(-7) - 6.30 x 10(-7) mol/dm(3) and 5.898 x 10(-7) - 2.11 x 10(-6) mol/dm(3) respectively. This method is reproducible and effective for determining the studied phenols in samples.
JOURNAL OF FLUORESCENCE
(2023)
Article
Biochemical Research Methods
Muhammad Idrees, Shah Hussain, Abdul Salam
Summary: The fluorescence quenching of phenanthrene in the anionic micellar system of sodium dodecyl sulphate (SDS) was investigated as a sensitive and selective method for a specific group of aldehydes. The experiments were conducted in a 0.02 mol L-1 SDS solution. All the studied aldehydes showed fluorescence quenching of the probe (phenanthrene). The Stern-Volmer equation was used to explain the phenanthrene quenching by the aldehydes, and the Stern-Volmer constants (K-SV) were obtained to evaluate the sensitivity of the method for the aldehydes. The phenanthrene fluorescence quenching by the aldehydes is valuable for their determination in environmental samples.
JOURNAL OF FLUORESCENCE
(2023)
Article
Polymer Science
Hyejin Kim, Byungjin Koo
Summary: Fluorescent conjugated polymers were reported to exhibit fluorescence quenching upon addition of Fe (III) ions, with alkyl functional PPE showing higher sensitivity than expected compared to triethylene glycol functional PPE. The polymer sensors displayed selectivity towards Fe3+ over other ions, and the quenching was determined to be static. A PPE-containing, fluorescent PDMS pad was developed for potential future applications in wearable sensor technology, demonstrating a dark stain when Fe solution was dropped on it.
MACROMOLECULAR RESEARCH
(2021)
Article
Biochemical Research Methods
Muhammad Naeem Khan, Syeda Qandeel Wajid Kazmi
Summary: This study used fluorescence-based techniques to examine the interaction between L-tryptophan and a selection of aldehydes. The results showed that all five aldehydes induced quenching of L-tryptophan's fluorescence intensity. The study also determined Stern-Volmer constants and detection limits for the investigated aldehydes. The findings have implications for the development of sensors and the analysis of aldehydes in environmental and biological samples.
JOURNAL OF FLUORESCENCE
(2023)
Article
Biochemical Research Methods
Muhammad Idrees, Abdul Salam
Summary: The study investigated the interaction of pyrene with selected amines in aqueous sodium dodecyl sulfate, revealing pyrene's ability to act as a sensitive sensor for detecting amines in environmental samples. Different concentrations of SDS were tested to determine the optimum conditions for maximum quenching and detection limits of pyrene. Stern-Volmer equation was used to calculate Stern-Volmer constants, reflecting pyrene's sensitivity towards the studied amines, with Benzylamine showing the highest sensitivity amongst the tested amines.
JOURNAL OF FLUORESCENCE
(2021)
Article
Chemistry, Physical
Serguei Feskov, Stanislav L. Bondarev, Tamara F. Raichenok, Sergei A. Tikhomirov, Anatoly I. Ivanov
Summary: A theory is developed to explain the fluorescence quenching of a centrosymmetric acridine-dione derivative induced by H-bonding interactions with solvents in mixtures of methanol and dimethylformamide. The theory considers both dynamic and static mechanisms of the quenching and explains the threshold-type dependence of the quenching efficiency on the concentration of methanol. A model of H-bond clustering in alcohol and H-bond-accepting solvent mixtures is proposed, which provides a quantitative description of the observed fluorescence yield and kinetics.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Biochemical Research Methods
Seba Merin Vinod, Sangeetha Murugan Sreedevi, Anju Krishnan, Tamizhdurai Perumal, Raghupathi Chinnadurai, Kumaran Rajendran
Summary: The molecular interactions between D-glucose and different types of ADR dyes were investigated using molecular docking and fluorescence spectral techniques. The results showed that the absorbance of PET dyes decreased in the presence of glucose, while the absorbance of non-PET dyes increased. PET dyes formed stable conformers with glucose through hydrogen bonding and hydrophobic interaction. On the other hand, there was no significant interaction observed between non-PET dyes and glucose. This study provides insights into the understanding of the interaction between different types of dyes and sugars.
JOURNAL OF FLUORESCENCE
(2023)
Article
Chemistry, Analytical
Reem H. Alzard, Harrison Meyer, Farah Benyettou, Ali Trabolsi, Na'il Saleh
Article
Biochemistry & Molecular Biology
Na'il Saleh, Muna S. Bufaroosha, Ziad Moussa, Rukayat Bojesomo, Hebah Al-Amodi, Asia Al-Ahdal
Article
Energy & Fuels
Tabinah Faisal, Kyril M. Solntsev, Tim Kahs, Na'il Saleh, Patrick Commins, Jamie Whelan, Sharmarke Mohamed, Pance Naumov
Summary: Quantification of molecular complexes between simple organic aromatic molecules is straightforward for pure components, but becomes challenging when dealing with complex mixtures of thousands of polycyclic aromatic hydrocarbons (PAHs). Fluorescence spectroscopy shows that electron-deficient aromatic additives interact strongly with PAHs, leading to the formation of molecular complexes. Computational modeling reveals that cohesive pi-pi stacking interactions between PAHs dominate as the number of PAH molecules in the cluster increases.
Article
Chemistry, Multidisciplinary
Na'il Saleh, Saad Al-Jassabi, Ali H. Eid, Werner M. Nau
Summary: In this study, it was found that the addition of CB7 significantly reduced Microcystis aeruginosa-induced hepatotoxicity, lowered liver enzyme activity, and oxidative stress levels in the liver.
FRONTIERS IN CHEMISTRY
(2021)
Article
Pharmacology & Pharmacy
Bharti R. K. Shyamlal, Manas Mathur, Dharmendra K. Yadav, Irina Mashevskaya, Mohamed El-Shazly, Na'il Saleh, Sandeep Chaudhary
Summary: The research identified 3-phenyl-1H-isochromen-1-one analogues as potent antioxidants and antiplatelet agents, with some compounds demonstrating greater activity than aspirin. In vitro and in silico studies confirmed the efficacy of these compounds.
CURRENT PHARMACEUTICAL DESIGN
(2022)
Article
Chemistry, Multidisciplinary
Lamia A. Siddig, Rukayat Bojesomo, Mohammad A. Khasawneh, Abdelouahid Samadi, Alejandro Perez Paz, Haythem A. Saadeh, Na'il Saleh
Summary: A novel multifunctional fluorescent molecule, Bz-8HQ, has been designed and synthesized with high yield. It exhibits responsiveness to multiple stimuli, including pH, CB7, and CAD, due to two distinct binding sites. Bz-8HQ also displays photoinduced electron transfer (PET) and fluorescence resonance energy transfer (FRET), making it a valuable tool in future biological and medical imaging applications.
NEW JOURNAL OF CHEMISTRY
(2021)
Review
Biochemistry & Molecular Biology
Rukayat S. Bojesomo, Na'il Saleh
Summary: This review explores the host-guest complexation of small heterocyclic and macrocyclic cavitands organic molecules in supramolecular chemistry, focusing on the mechanisms and applications within the past 15 years. By understanding specific factors such as encapsulation modes and assembly structures, the manipulation of photoinduced electron transfer (PET) processes can be effectively controlled.
PHOTOCHEMISTRY AND PHOTOBIOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Rukayat S. Bojesomo, Khaleel Assaf, Haythem A. Saadeh, Lamia A. Siddig, Na'il Saleh
Summary: A new fluorescent dye complexed with CB7 was designed to detect carnosol, an anti-breast cancer drug, utilizing the supramolecular indicator displacement assay strategy, the CB7-assisted pK(a) shift, and the CB7-retarded photoinduced electron transfer process. The complexation was confirmed by spectroscopic methods, and a sensitive sensor for the detection of CAR in aqueous solution was achieved.
Article
Materials Science, Multidisciplinary
Narender Kumar, Na'il Saleh, Nacir Tit
Summary: In this study, density-functional theory (DFT) was used to investigate the induced magnetization in nitrogen-doped carbon nanotubes (ACNT:N) and the effect of an electric field. The results showed that ferromagnetism/anti-ferromagnetism can be achieved when nitrogen dopant atoms are arranged in a chain-like manner, and that a strong transversal electric field can induce magnetization in ACNT:N. The study is of great significance for spintronics and gas-sensing devices.
JOURNAL OF MATERIALS SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Narender Kumar, Vijo Poulose, Youssef Taiser Laz, Falguni Chandra, Salma Abubakar, Abdalla S. Abdelhamid, Ahmed Alzamly, Na'il Saleh
Summary: This study investigates the effects of temperature on the photoluminescence from ZnO-SiO2 nanocomposite and successfully prepares SiO2-coated ZnO nanocrystals. The results reveal two emission bands and identify the sources of these emissions. The presence of SiO2 increases the exciton lifetime values and the occurrence of thermally induced nonradiative recombination transfer.
Article
Polymer Science
Maryam Alhefeiti, Falguni Chandra, Ravindra Kumar Gupta, Na'il Saleh
Summary: Despite the environmental damage caused by plastic waste, this study explores the loading of dye from natural resources onto plastic films and discusses the potential application in ionic solar cells.
Article
Chemistry, Multidisciplinary
Mohammed A. A. Meetani, Ahmad Alhalabi, Mohammed K. K. Al-Tabaji, Abdulla Al-Hemyari, Haythem A. A. Saadeh, Na'il Saleh
Summary: In this study, sensitive spectrofluorometry and liquid chromatography with fluorescence detection were used to detect and determine the naproxen drug, and it was found that the addition of cucurbit7uril (CB7) improved the fluorescence signals. The guest-host interaction between naproxen and cucurbiturils was investigated using fluorescence spectroscopy, mass spectrometry, H-1-NMR, and liquid chromatography with fluorescence detection. It was discovered that naproxen formed a supramolecular complex with CB7, and the optimal conditions for the interaction were determined. HPLC with a fluorescence detector was then used to detect naproxen in wastewater samples by sample enrichment. The measured concentrations of naproxen in the influent and effluent wastewater were determined.
FRONTIERS IN CHEMISTRY
(2022)
Article
Nanoscience & Nanotechnology
Falguni Chandra, Maria Bykova, Vijo Poulose, Paltan Laha, Alina Aktanova, Olga Boeva, Margarita Barkovskaya, Ekaterina Pashkina, Na'il Saleh
Summary: In this study, a non-classical supramolecular strategy was used to enhance the cellular uptake of drug carriers. A model host-guest complex was created, in which a fluorescent tag VG was encapsulated by CB8 and covalently linked to ALG. The modification of the drug vehicle improved its rigidity, size reduction, and charge turnover, leading to enhanced internalization in cells.
Article
Chemistry, Multidisciplinary
Gobinda Das, Sudhir Kumar Sharma, Thirumurugan Prakasam, Felipe Gandara, Renny Mathew, Nour Alkhatib, Na'il Saleh, Renu Pasricha, John-Carl Olsen, Maria Baias, Serdal Kirmizialtin, Ramesh Jagannathan, Ali Trabolsi
COMMUNICATIONS CHEMISTRY
(2019)
Article
Chemistry, Multidisciplinary
Reem H. Alzard, Muna S. Bufaroosha, Noura Al-Shamsi, Amir Sohail, Naji Al-Dubaili, Alaa A. Salem, Ibrahim M. Abdou, Na'il Saleh
