Dual functions of Insig proteins in cholesterol homeostasis

Characterization of the Human Insulin-induced Gene 2 (INSIG2) Promoter

(2010) Ana Fernández-Alvarez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hair Growth Defects in Insig-Deficient Mice Caused by Cholesterol Precursor Accumulation and Reversed by Simvastatin

(2010) Bret M. Evers et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Insulin-induced gene: A new regulator in lipid metabolism

(2010) Xiao-Ying Dong et al.   PEPTIDES

Insig-mediated, Sterol-accelerated Degradation of the Membrane Domain of Hamster 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase in Insect Cells

(2009) Andrew D. Nguyen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intramembrane glycine mediates multimerization of Insig-2, a requirement for sterol regulation in Chinese hamster ovary cells

(2009) Peter C. W. Lee et al.   JOURNAL OF LIPID RESEARCH

Dislocation of HMG-CoA Reductase and Insig-1, Two Polytopic Endoplasmic Reticulum Proteins, En Route to Proteasomal Degradation

(2009) Gil S. Leichner et al.   MOLECULAR BIOLOGY OF THE CELL

The single nucleotide polymorphism upstream of insulin-induced gene 2 ( INSIG2) is associated with the prevalence of hypercholesterolaemia, but not with obesity, in Japanese American women

(2008) Kenji Oki et al.   BRITISH JOURNAL OF NUTRITION

Insig Regulates HMG-CoA Reductase by Controlling Enzyme Phosphorylation in Fission Yeast

(2008) John S. Burg et al.   Cell Metabolism