Article
Psychology, Developmental
T. Christina Zhao, Neva M. Corrigan, Vasily L. Yarnykh, Patricia K. Kuhl
Summary: This study investigates the development of executive function skills in infants and finds a strong correlation between neural structure and function with task performance. The study also reveals that myelin density at 7 months can predict task performance at 11 months, and individual differences in task performance are related to concurrent neural speech processing.
DEVELOPMENTAL SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Pinduo Liu, Anping Wu, Hui Li, Jun Zhang, Junjun Ni, Zhenzhen Quan, Hong Qing
Summary: This study revealed the degradation pathways of Rab21 protein through the ubiquitin-proteasome pathway and the autophagy-lysosome pathway, and demonstrated increased ubiquitination of Rab21 protein in the AD model. Moreover, the study suggested the involvement of the autophagy-lysosome pathway in maintaining the protein level of Rab21.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Engineering, Environmental
Yilin Zhang, Garret D. Bland, Jiajun Yan, Astrid Avellan, Jiang Xu, Zongyu Wang, Thomas P. Hoelen, Francisco Lopez-Linares, Evan S. Hatakeyama, Krzysztof Matyjaszewski, Robert D. Tilton, Gregory Lowry
Summary: The newly developed polymer nanogel can efficiently remove environmentally relevant mercury species from both produced water and liquid hydrocarbon, showing significant potential for applications.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2021)
Article
Biology
Mojtaba Mokari, Hossein Moeini, Shahnaz Farazmand
Summary: In this study, the repair kinetics of DNA double-strand breaks (DSBs) caused by carbon ions and electrons were investigated using Monte Carlo simulation. The results showed that the repair time of carbon ions increased with the complexity of DSBs, while there were discrepancies between the calculated repair kinetics and experimental results for electrons. This study provides important insights into the repair mechanisms of DSBs.
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
(2023)
Article
Environmental Sciences
Hem Raj Bhattarai, Wolfgang Wanek, Henri M. P. Siljanen, Jussi G. Ronkainen, Maarit Liimatainen, Yuntao Hu, Hannu Nykanen, Christina Biasi, Marja Maljanen
Summary: Microbial processes, especially denitrification, are found to be the main driver of nitrous acid (HONO) production and emissions in aerobic soils, exceeding the contributions of abiotic processes according to N-15 tracer and isotope pool dilution experiments in boreal agricultural soils. The research highlights the significance of microbial nitrate reduction as a key HONO production pathway in soils, with potential implications for atmospheric chemistry.
COMMUNICATIONS EARTH & ENVIRONMENT
(2021)
Article
Psychiatry
Christina Elling, Andreas J. Forstner, Laura-Effi Seib-Pfeifer, Martin Muecke, Jutta Stahl, Franziska Geiser, Johannes Schumacher, Rupert Conrad
Summary: Individuals with social anxiety disorder (SAD) often experience comorbid major depressive disorder (MDD), which leads to greater clinical and functional impairment. This study aimed to investigate the differences in childhood adversities and attachment styles between individuals with SAD with and without comorbid MDD. The findings showed that the SAD-MDD group had more severe SAD symptoms, experienced more childhood adversities, and had higher levels of fearful attachment style compared to the SAD group. Fearful attachment style played a significant role in mediating the association between childhood adversities and SAD symptom severity in the SAD-MDD group.
JOURNAL OF PSYCHIATRIC RESEARCH
(2022)
Article
Psychology, Clinical
Wen-tao Lai, Wen-feng Deng, Shu-xian Xu, Jie Zhao, Dan Xu, Yang-hui Liu, Yuan-yuan Guo, Ming-bang Wang, Fu-sheng He, Shu-wei Ye, Qi-fan Yang, Tie-bang Liu, Ying-li Zhang, Sheng Wang, Min-zhi Li, Ying-jia Yang, Xin-hui Xie, Han Rong
Summary: This study found changes in gut microbiota and the Trp pathway in MDD patients, with an increase in Bifidobacterium levels and decreased abundances of certain KEGG orthologies in the MiTBamp. A negative correlation was also observed between K01626 abundance and HAMD scores in the MDD group. The findings suggest that alterations in gut microbiota could potentially serve as biomarkers for distinguishing MDD patients from healthy controls.
PSYCHOLOGICAL MEDICINE
(2021)
Article
Biochemistry & Molecular Biology
Ruth M. Urbantat, Anne Blank, Irina Kremenetskaia, Peter Vajkoczy, Gueliz Acker, Susan Brandenburg
Summary: The study found that in glioblastoma, the overexpression of VEGF and CXCL2 was associated with decreased patient survival. However, while there were correlations among molecules in the VEGF pathway, no significant relationship was found between CXCR1/2 and CXCL2/IL8. Brain endothelial cells reacted differently to various proangiogenic molecules compared to peripheral endothelial cells, and treatment with a CXCR2 antagonist reduced endothelial cell motility and sprouting.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Geosciences, Multidisciplinary
Pere Rovira, Teresa Sauras-Yera, Joan Romanya
Summary: This study examines the biases in soil organic carbon (SOC) sequestration estimation caused by different approaches. The results show that the fixed-depth approach tends to overestimate SOC sequestration under soil compaction and underestimate it under soil expansion. However, the overall error is low. The study suggests that current estimates of SOC sequestration worldwide, at least in relation to the problem studied, do not require significant revisions. The equivalent-mass approach is necessary for SOC sequestration studies, but may not be suitable for global comparisons of SOC stocks when compared to the fixed-depth approach.
Article
Microbiology
Luke R. R. Green, Rahaf Issa, Fawzyah Albaldi, Lucy Urwin, Ruth Thompson, Henna Khalid, Claire E. E. Turner, Barbara Ciani, Lynda J. J. Partridge, Peter N. N. Monk
Summary: This article investigates the role of the host membrane adapter protein CD9 in Staphylococcus aureus adhesion to epithelial cells. The study demonstrates that CD9 is essential for syndecan-mediated bacterial adhesion and that it coordinates with fibronectin to promote bacterial adherence and internalization. Insights from this research may lead to the development of alternative anti-adhesion treatments for staphylococcal infections.
Article
Biochemistry & Molecular Biology
Birgit Lohberger, Sandra Barna, Dietmar Glanzer, Nicole Eck, Sylvia Kerschbaum-Gruber, Katharina Stasny, Andreas Leithner, Dietmar Georg
Summary: Chondrosarcomas are difficult to treat with chemotherapy and radiotherapy, but particle therapy can enhance the treatment effectiveness. Increasing ionization density inhibits cell viability and proliferation, and causes G(2)/M arrest. Particle irradiation upregulates senescence genes, and proton or carbon ion radiation positively regulates repair genes more significantly.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Multidisciplinary Sciences
Rebecca Josefson, Navinder Kumar, Xinxin Hao, Beidong Liu, Thomas Nystrom
Summary: A hallmark of aging is the breakdown of proteostasis and the accumulation of protein aggregates. In this study, the GET pathway was identified as a bottleneck in proteostasis, as mutations in GET genes caused the accumulation of protein aggregates.
SCIENTIFIC REPORTS
(2023)
Article
Oncology
Katharina Seidensaal, Matthias Mattke, Sabine Haufe, Hendrik Rathke, Uwe Haberkorn, Nina Bougatf, Andreas Kudak, Claudia Blattmann, Susanne Oertel, Marietta Kirchner, Christopher Buesch, Meinhard Kieser, Klaus Herfarth, Andreas Kulozik, Jurgen Debus, Matthias Uhl, Semi B. Harrabi
Summary: The study indicates that combined ion-beam radiotherapy may offer promising results and better toxicity profile for long-term inoperable craniofacial osteosarcoma patients.
RADIOTHERAPY AND ONCOLOGY
(2021)
Article
Biochemical Research Methods
Nastaran Ebrahimi, Jahan Bakhsh Raoof, Reza Ojani, Maryam Ebrahimi
Summary: This work presents a novel electrochemical biosensor for the detection of Ba2+ ions, utilizing G-quadruplex DNA and a Carbon Paste Electrode modified with Ag nanoparticles incorporated in reduced Graphene Oxide. The biosensor showed good selectivity towards Ba2+ ions in the presence of other metal ions and achieved a low Limit of Detection. It was successfully applied for the analysis of natural samples.
ANALYTICAL BIOCHEMISTRY
(2022)
Article
Optics
O. A. Krohn, K. J. Catani, H. J. Lewandowski
Summary: This study investigates the gas-phase ion-neutral reaction of CCl+ with benzene (C6H6) and observes various products, with C7H5+ being favored. Electronic structure calculations provide thermodynamic limits for the reaction and allow for the assignment of reaction products to specific structural isomers. The results broaden our understanding of the reactivity and possible role of CCl+ and C6H6 in interstellar chemistry.
Article
Multidisciplinary Sciences
Lue Sun, Yohei Inaba, Keizo Sato, Aki Hirayama, Koji Tsuboi, Ryuji Okazaki, Koichi Chida, Takashi Moritake
SCIENTIFIC REPORTS
(2018)
Article
Multidisciplinary Sciences
Lue Sun, Takashi Moritake, Kazuya Ito, Yoshitaka Matsumoto, Hironobu Yasui, Hidehiko Nakagawa, Aki Hirayame, Osamu Inanami, Koji Tsuboi
Article
Oncology
Yuzi Wang, Junko Zenkoh, Ariungerel Gerelchuluun, Lue Sun, Songjie Cai, Xiaokang Li, Koji Tsuboi
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
(2019)
Article
Environmental Sciences
Satoru Kawauchi, Koichi Chida, Takashi Moritake, Yuji Matsumaru, Yusuke Hamada, Hideyuki Sakuma, Shogo Yoda, Lue Sun, Masayuki Sato, Wataro Tsuruta
RADIATION PROTECTION DOSIMETRY
(2019)
Article
Biology
Lue Sun, Tomonori Igarashi, Ryoya Tetsuka, Yun-Shan Li, Yuya Kawasaki, Kazuaki Kawai, Haruhisa Hirakawa, Koji Tsuboi, Asako J. Nakamura, Takashi Moritake
JOURNAL OF RADIATION RESEARCH
(2019)
Article
Oncology
Masaoki Kohzaki, Akira Ootsuyama, Lue Sun, Takashi Moritake, Ryuji Okazaki
INTERNATIONAL JOURNAL OF CANCER
(2020)
Article
Biochemistry & Molecular Biology
Lue Sun, Yohei Inaba, Norie Kanzaki, Mahesh Bekal, Koichi Chida, Takashi Moritake
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2020)
Article
Environmental Sciences
Satoru Kawauchi, Koichi Chida, Takashi Moritake, Yusuke Hamada, Yuji Matsumaru, Wataro Tsuruta, Masayuki Sato, Hisayuki Hosoo, Lue Sun
RADIATION PROTECTION DOSIMETRY
(2020)
Article
Medicine, General & Internal
Koichi Morota, Takashi Moritake, Keisuke Nagamoto, Satoru Matsuzaki, Koichi Nakagami, Lue Sun, Naoki Kunugita
Summary: Understanding the maximum skin dose in cerebral angiography is crucial for avoiding tissue reactions. This study developed a method using DICOM-RDSR data to accurately estimate the maximum skin dose from Total K-a,K-r. Results showed that using a quadratic function estimation model provided a more accurate estimate compared to a constant estimation model.
Article
Environmental Sciences
Norie Kanzaki, Akihiro Sakoda, Takahiro Kataoka, Lue Sun, Hiroshi Tanaka, Iwao Ohtsu, Kiyonori Yamaoka
Summary: In this study, the changes in metabolites in mouse brains after radon inhalation were comprehensively analyzed, with a focus on glutathione. The results showed that the levels of glutathione-related substances changed after radon inhalation, indicating a shift in the state of sulfur-related metabolites. These metabolites play a biological defense role against the imbalance of the redox state following radon inhalation.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Meeting Abstract
Oncology
Y. Wang, L. Sun, X. Li, K. Tsuboi
ANNALS OF ONCOLOGY
(2018)
Meeting Abstract
Oncology
Yuzi Wang, Lue Sun, Xiaokang Li, Koji Tsuboi
Meeting Abstract
Oncology
Yuzi Wang, Lue Sun, Xiaokang Li, Koji Tsuboi
Meeting Abstract
Oncology
Lue Sun, Yuzi Wang, Masaoki Kohzaki, Koji Tsuboi
Meeting Abstract
Oncology
Yuzi Wang, Lue Sun, Xiaokang Li, Koji Tsuboi
JOURNAL OF CLINICAL ONCOLOGY
(2017)