Constitutive phosphorylation of the active Notch1 intracellular domain in chronic lymphocytic leukemia cells with NOTCH1 mutation

The Molecular Basis of Notch Signaling Regulation: A Complex Simplicity

(2014) R. Palermo et al.   CURRENT MOLECULAR MEDICINE

A revised NOTCH1 mutation frequency still impacts survival while the allele burden predicts early progression in chronic lymphocytic leukemia

(2013) P Sportoletti et al.   LEUKEMIA

Functional impact of NOTCH1 mutations in chronic lymphocytic leukemia

(2013) F Arruga et al.   LEUKEMIA

Glycogen synthase kinase 3-β phosphorylates novel S/T-P-S/T domains in Notch1 intracellular domain and induces its nuclear localization

(2012) Xiangzi Han et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Emerging role of kinase-targeted strategies in chronic lymphocytic leukemia

(2012) A. Wiestner   BLOOD

Hierarchical Phosphorylation within the Ankyrin Repeat Domain Defines a Phosphoregulatory Loop That Regulates Notch Transcriptional Activity

(2011) Prathibha Ranganathan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reconstitution of PTEN activity by CK2 inhibitors and interference with the PI3-K/Akt cascade counteract the antiapoptotic effect of human stromal cells in chronic lymphocytic leukemia

(2010) M. Shehata et al.   BLOOD

NOTCH1 PEST domain mutation is an adverse prognostic factor in B-CLL

(2010) Paolo Sportoletti et al.   BRITISH JOURNAL OF HAEMATOLOGY

Constitutively activated Notch signaling is involved in survival and apoptosis resistance of B-CLL cells

(2008) E. Rosati et al.   BLOOD

Down-regulation of Notch-dependent transcription by Akt in vitro

(2008) Jieun Song et al.   FEBS LETTERS