Sequencing histone-modifying enzymes identifies UTX mutations in acute lymphoblastic leukemia

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

(2012) Jinghui Zhang et al.   NATURE

DNA methylation profiling in acute myeloid leukemia: from recent technological advances to biological and clinical insights

(2010) Rainer Claus et al.   Future Oncology

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

(2010) Gillian L. Dalgliesh et al.   NATURE

Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin

(2010) Ryan D Morin et al.   NATURE GENETICS

Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders

(2010) Thomas Ernst et al.   NATURE GENETICS

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

The Genetic Landscape of the Childhood Cancer Medulloblastoma

(2010) D. W. Parsons et al.   SCIENCE

The molecular biology of mixed lineage leukemia

(2009) R. K. Slany   HAEMATOLOGICA

Chromatin maps, histone modifications and leukemia

(2009) T Neff et al.   LEUKEMIA

Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer

(2009) Gijs van Haaften et al.   NATURE GENETICS

Stratification of pediatric ALL by in vitro cellular responses to DNA double-strand breaks provides insight into the molecular mechanisms underlying clinical response

(2008) E. Marston et al.   BLOOD

An 86-probe-set gene-expression signature predicts survival in cytogenetically normal acute myeloid leukemia

(2008) K. H. Metzeler et al.   BLOOD

Translating insights from the cancer genome into clinical practice

(2008) Lynda Chin et al.   NATURE