The leukemogenic AF4–MLL fusion protein causes P-TEFb kinase activation and altered epigenetic signatures

The AF4{middle dot}MLL fusion protein is capable of inducing ALL in mice without requirement of MLL{middle dot}AF4

(2010) A. Bursen et al.   BLOOD

A Higher-Order Complex Containing AF4 and ENL Family Proteins with P-TEFb Facilitates Oncogenic and Physiologic MLL-Dependent Transcription

(2010) Akihiko Yokoyama et al.   CANCER CELL

AFF4, a Component of the ELL/P-TEFb Elongation Complex and a Shared Subunit of MLL Chimeras, Can Link Transcription Elongation to Leukemia

(2010) Chengqi Lin et al.   MOLECULAR CELL

Chromatin Flow Cytometry Identifies Changes in Epigenetic Cell States

(2009) Nadine Obier et al.   CELLS TISSUES ORGANS

CARM1 but not Its Enzymatic Activity Is Required for Transcriptional Coactivation of NF-κB-Dependent Gene Expression

(2009) Sandrine Jayne et al.   JOURNAL OF MOLECULAR BIOLOGY

New insights to the MLL recombinome of acute leukemias

(2009) C Meyer et al.   LEUKEMIA

Misguided Transcriptional Elongation Causes Mixed Lineage Leukemia

(2009) Dorothee Mueller et al.   PLOS BIOLOGY

H3K79 Methylation Profiles Define Murine and Human MLL-AF4 Leukemias

(2008) Andrei V. Krivtsov et al.   CANCER CELL

Nucleophosmin Interacts with HEXIM1 and Regulates RNA Polymerase II Transcription

(2008) Meera Gurumurthy et al.   JOURNAL OF MOLECULAR BIOLOGY

Elastase Digests

(2008) Benjamin Rietschel et al.   MOLECULAR & CELLULAR PROTEOMICS

DOT1L/KMT4 Recruitment and H3K79 Methylation Are Ubiquitously Coupled with Gene Transcription in Mammalian Cells

(2008) D. J. Steger et al.   MOLECULAR AND CELLULAR BIOLOGY

Brd4 Coactivates Transcriptional Activation of NF- B via Specific Binding to Acetylated RelA

(2008) B. Huang et al.   MOLECULAR AND CELLULAR BIOLOGY

STRING 8--a global view on proteins and their functional interactions in 630 organisms

(2008) L. J. Jensen et al.   NUCLEIC ACIDS RESEARCH