Aurora kinase inhibitors: novel small molecules with promising activity in acute myeloid and Philadelphia-positive leukemias
出版年份 2010 全文链接
标题
Aurora kinase inhibitors: novel small molecules with promising activity in acute myeloid and Philadelphia-positive leukemias
作者
关键词
-
出版物
LEUKEMIA
Volume 24, Issue 4, Pages 671-678
出版商
Springer Nature
发表日期
2010-02-11
DOI
10.1038/leu.2010.15
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Epidemiologic study on survival of chronic myeloid leukemia and Ph+ acute lymphoblastic leukemia patients with BCR-ABL T315I mutation
- (2009) F. E. Nicolini et al. BLOOD
- AC220 is a uniquely potent and selective inhibitor of FLT3 for the treatment of acute myeloid leukemia (AML)
- (2009) P. P. Zarrinkar et al. BLOOD
- Enhanced activation of STAT pathways and overexpression of survivin confer resistance to FLT3 inhibitors and could be therapeutic targets in AML
- (2009) J. Zhou et al. BLOOD
- KW-2449, a novel multikinase inhibitor, suppresses the growth of leukemia cells with FLT3 mutations or T315I-mutated BCR/ABL translocation
- (2009) Y. Shiotsu et al. BLOOD
- AZD1152 Rapidly and Negatively Affects the Growth and Survival of Human Acute Myeloid Leukemia Cells In vitro and In vivo
- (2009) A. Oke et al. CANCER RESEARCH
- A Phase I Dose-Escalation Study of Danusertib (PHA-739358) Administered as a 24-Hour Infusion with and without Granulocyte Colony-Stimulating Factor in a 14-Day Cycle in Patients with Advanced Solid Tumors
- (2009) R. B. Cohen et al. CLINICAL CANCER RESEARCH
- Preclinical characterization of Aurora kinase inhibitor R763/AS703569 identified through an image-based phenotypic screen
- (2009) John McLaughlin et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Chronic myeloproliferative diseases with and without the Ph chromosome: some unresolved issues
- (2009) J M Goldman et al. LEUKEMIA
- Aurora-A kinase: a novel target of cellular immunotherapy for leukemia
- (2008) T. Ochi et al. BLOOD
- Simultaneous targeting of Aurora kinases and Bcr-Abl kinase by the small molecule inhibitor PHA-739358 is effective against imatinib-resistant BCR-ABL mutations including T315I
- (2008) A. Gontarewicz et al. BLOOD
- Concomitant inhibition of Mdm2-p53 interaction and Aurora kinases activates the p53-dependent postmitotic checkpoints and synergistically induces p53-mediated mitochondrial apoptosis along with reduced endoreduplication in acute myelogenous leukemia
- (2008) K. Kojima et al. BLOOD
- A pharmacodynamic study of the FLT3 inhibitor KW-2449 yields insight into the basis for clinical response
- (2008) K. W. Pratz et al. BLOOD
- Strategies to reduce the risk of drug-induced QT interval prolongation: a pharmaceutical company perspective
- (2008) C E Pollard et al. BRITISH JOURNAL OF PHARMACOLOGY
- Aurora Kinases as Anticancer Drug Targets
- (2008) O. Gautschi et al. CLINICAL CANCER RESEARCH
- Cotreatment with Vorinostat Enhances Activity of MK-0457 (VX-680) against Acute and Chronic Myelogenous Leukemia Cells
- (2008) W. Fiskus et al. CLINICAL CANCER RESEARCH
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