Article
Medicine, Research & Experimental
Brett A. Campbell, Victoria B. Flormann, Roger B. Davis, Pavan S. Mallur
Summary: This study aimed to investigate the efficacy and related factors of electromyography (EMG)-guided laryngeal onobotulinumtoxinA (BTxA) injection for chronic cough. The results showed that BTxA injection effectively improved cough quality and reduced Cough Severity Index (CSI), with minimal risk of complications. Pulmonary disease and vocal fold hypomobility were not significantly correlated with treatment efficacy.
Article
Otorhinolaryngology
Yufei Pan, Jinrang Li, Jinhong Zhang, Xiaoyu Wang, Yuanyuan Jia
Summary: Injecting botulinum toxin A into the thyroarytenoid muscle via the thyrohyoid membrane approach is an effective method for treating refractory laryngeal contact granuloma, with a total efficacy rate of 82.61%, and no serious complications occurred.
AMERICAN JOURNAL OF OTOLARYNGOLOGY
(2022)
Article
Clinical Neurology
Yaowen Hu, Lizhen Pan, Junhui Su, Shuzhen Chen, Xiaolong Zhang, Yougui Pan, Lingjing Jin, Fei Teng
Summary: This study characterized the target muscles involved in retroform cervical dystonia (RCD) and evaluated the efficacy of botulinum toxin type A (BTX-A) injection. The most frequently injected muscles in RCD were splenius capitis, semispinalis capitis, levator scapulae, rectus capitis posterior major, trapezius, and sternocleidomastoid muscle. BTX-A injection achieved a satisfactory therapeutic effect in RCD, with a symptom relief rate of 69.0 +/- 16.7%.
FRONTIERS IN NEUROLOGY
(2022)
Article
Health Care Sciences & Services
Yu-Hua Fan, Hann-Chorng Kuo
Summary: This study aimed to evaluate the efficacy of intravesical botulinum toxin A (BoNT-A) injections for the treatment of pediatric overactive bladder (OAB). The study demonstrated that intravesical BoNT-A injection is effective and safe for the treatment of neurogenic and non-neurogenic OAB in children refractory to conventional therapies.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Audiology & Speech-Language Pathology
Amy Rutt, Kathleen D. Kennelly, Jhon F. Martinez-Paredes
Summary: This study explores nonbiological factors that can affect the patient experience during Laryngeal Botulinum Toxin injection (LBTX) therapy for Adductor Spasmodic Dysphonia. The study identifies preprocedure education, body position, pain, and stress sensation as potential factors influencing treatment outcomes.
Article
Multidisciplinary Sciences
Tae-Hyeon Cho, Ju-Eun Hong, Hun-Mu Yang
Summary: In this study, the dominant fibers within each compartment of the subscapularis muscle were determined using immunohistochemistry with fresh cadavers. The results showed distinct fascia demarcating the superior and inferior compartments of the muscle. The innervation of the muscle by the upper and lower subscapular nerves was also observed, and the densities of type I and type II fibers were found to differ between the compartments.
SCIENTIFIC REPORTS
(2023)
Article
Dermatology
Sun Hye Shin, Su Jung Park, Seung Hoon Yeoum, Choon Shik Youn, Kui Young Park
Summary: This study evaluated the efficacy and safety of intramuscular injection of BTX in reducing deltoid muscle hypertrophy, showing a significant decrease in muscle thickness and improvement in clinical assessment scores post-treatment, although patient satisfaction scores were relatively low. No major complications were reported, suggesting that BTX-A injection may be a novel treatment option for deltoid muscle hypertrophy. Further larger clinical studies are warranted to confirm its efficacy.
DERMATOLOGIC THERAPY
(2021)
Article
Clinical Neurology
Lena C. O'Flynn, Kristina Simonyan
Summary: This study investigated the short-term and long-term effects of BoNT treatment on brain function in patients with LD. The results suggest that BoNT-treated patients who benefited from the treatment had reduced activity in the left precuneus compared to untreated patients and patients who did not benefit from the treatment. Additionally, BoNT-treated patients with adductor LD showed decreased activity in the right thalamus, while patients with abductor LD showed reduced activity in the left inferior frontal cortex. There were no significant differences in brain activity between patients with shorter and longer treatment durations. However, patients with intermediate treatment duration of 6-12 years showed reduced activity in the right cerebellum and right prefrontal cortex compared to patients with shorter treatment duration.
Article
Clinical Neurology
Masamitsu Hyodo, Asuka Nagao, Kento Asano, Masahiko Sakaguchi, Kenji Mizoguchi, Koichi Omori, Yasuhiro Tada, Hiromitsu Hatakeyama, Nobuhiko Oridate, Kensei Naito, Yoshihiro Iwata, Hirotaka Shinomiya, Hirotaka Hara, Tetsuji Sanuki, Eiji Yumoto
Summary: Botulinum toxin injection is safe and effective for the treatment of spasmodic dysphonia, leading to approval as a treatment in Japan. The study showed significant improvements in aberrant morae, voice quality, and subjective parameters, with mild and temporary adverse events.
EUROPEAN JOURNAL OF NEUROLOGY
(2021)
Article
Surgery
Hussain Adnan Aldhaher, Salwan Y. Bede
Summary: This study demonstrates the effectiveness of botulinum toxin injection as a conservative treatment for excessive gingival display due to muscular hyperfunction. The 4-points injection method resulted in better clinical measurements and satisfaction compared to the 2-points method.
JOURNAL OF CRANIOFACIAL SURGERY
(2022)
Review
Medicine, General & Internal
Giuseppina Malcangi, Assunta Patano, Carmela Pezzolla, Lilla Riccaldo, Antonio Mancini, Chiara Di Pede, Alessio Danilo Inchingolo, Francesco Inchingolo, Ioana Roxana Bordea, Gianna Dipalma, Angelo Michele Inchingolo
Summary: Botulinum toxin (BTA) is a bacterial-derived extract that inhibits muscle contraction by affecting the absorption of acetylcholine. It has been widely used in aesthetic and general medicine, and recent research has explored its application for addressing bruxism.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Orthopedics
Jorge Elizondo-Rodriguez, Mario Simental-Mendia, Victor Pena-Martinez, Felix Vilchez-Cavazos, Yadira Tamez-Mata, Carlos Acosta-Olivo
Summary: In this study, researchers compared three injection therapies for plantar fasciitis and found that all patients showed improvement in clinical outcomes, with no significant differences between treatment groups. The pain relief and functional improvement obtained with the different treatments was maintained during the 6-month follow-up.
FOOT & ANKLE INTERNATIONAL
(2021)
Article
Clinical Neurology
Christopher D. Dwyer, Andree-Anne Leclerc, Sanjeev D. Nandedkar, VyVy N. Young, Clark A. Rosen
Summary: The study of 45 AdSD patients revealed that aiming for an NSS value greater than 200 during phonation prior to BoNT-A toxin injection may reduce unfavorable voice outcomes.
Review
Food Science & Technology
Shu-Yu Wu, Shang-Jen Chang, Stephen Shei-Dei Yang, Chun-Kai Hsu
Summary: The study evaluated the use of BTX-A injection in children with medically refractory neurogenic bladder, finding it to be a safe and effective treatment option. Improvements in clinical and urodynamic parameters were observed as the main outcomes of the treatment.
Review
Ophthalmology
Desheng Song, Jing Qian, Zhijun Chen
Summary: This study compared the effectiveness of botulinum toxin injection (BTX) and bilateral medial rectus recession (BMR) in the treatment of comitant esotropia. The results showed that BMR had a higher success rate and a lower undercorrection rate compared to BTX, particularly for infantile esotropia. However, there were similar treatment effects between BTX and BMR in the treatment of acute acquired comitant esotropia.
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2023)
