Review
Clinical Neurology
Simona Sacco, Christian Lampl, Faisal Mohammad Amin, Mark Braschinsky, Christina Deligianni, Derya Uluduz, Jan Versijpt, Anne Ducros, Raquel Gil-Gouveia, Zaza Katsarava, Paolo Martelletti, Raffaele Ornello, Bianca Raffaelli, Deirdre M. Boucherie, Patricia Pozo-Rosich, Margarita Sanchez-del-Rio, Alexandra Sinclair, Antoinette Maassen van den Brink, Uwe Reuter
Summary: This study aims to provide a definition of triptan failure, which can quantitatively assess the efficacy of triptans in clinical practice and help explore new acute migraine treatments.
JOURNAL OF HEADACHE AND PAIN
(2022)
Article
Clinical Neurology
John H. Krege, Richard B. Lipton, Simin K. Baygani, Mika Komori, Sinead M. Ryan, Maurice Vincent
Summary: The efficacy of lasmiditan in patients with and without triptan contraindications did not differ. Lasmiditan may be a treatment option for patients with contraindications to triptans.
Article
Medicine, General & Internal
Seonkyeong Yang, Yulia Orlova, Abigale Lipe, Macy Boren, Juan M. Hincapie-Castillo, Haesuk Park, Ching-Yuan Chang, Debbie L. Wilson, Lauren Adkins, Wei-Hsuan Lo-Ciganic
Summary: The study found a significant decrease in opioid use among headache patients in US emergency departments, while there was an increasing trend in the use of acetaminophen/NSAIDs, diphenhydramine, and corticosteroids. Referrals for outpatient follow-up slightly increased over time.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Clinical Neurology
Jennifer Robblee, Karissa A. Secora
Summary: Although sinus headache is commonly associated with allergies or sinus infections, most cases are actually migraine. Understanding the differences between sinusitis and migraine can help clinicians accurately diagnose and treat patients, while also avoiding unnecessary investigations and treatments. Migraine medications can be effective for treating sinus headaches and can also serve as a diagnostic tool.
CURRENT NEUROLOGY AND NEUROSCIENCE REPORTS
(2021)
Article
Clinical Neurology
Ruth Ruscheweyh, Gudrun Gossrau, Thomas Dresler, Tobias Freilinger, Stefanie Foerderreuther, Charly Gaul, Torsten Kraya, Lars Neeb, Victoria Ruschil, Andreas Straube, Joerg Scheidt, Tim Patrick Juergens
Summary: Triptans are effective for many migraine patients, but 13.1% of patients in specialized headache care in Germany have failed >= 2 triptans, showing increased migraine severity and disability associated with triptan failure. Establishing an effective and tolerable acute migraine medication is important for optimizing treatment strategies.
JOURNAL OF HEADACHE AND PAIN
(2023)
Article
Clinical Neurology
Adriana Pero, Anna Pace, Mandip S. Dhamoon
Summary: This study aimed to investigate the prevalence of triptan use among patients with migraine who have contraindications to triptan usage and the specifics of the medication prescribed. The results showed that a considerable proportion of patients with contraindications were still prescribed triptan medication.
Article
Obstetrics & Gynecology
Benedetta Pasquini, Viola Seravalli, Silvia Vannuccini, Francesco La Torre, Pierangelo Geppetti, Luigi Iannone, Silvia Benemei, Felice Petraglia
Summary: In women with endometriosis, many experience headache, and about 53.4% of them are diagnosed with migraine. Among these, 18.6% have pure menstrual migraine, 45.7% have menstrually related migraine, and 35.7% have non-menstrual migraine. Patients with endometriosis and migraine are more likely to have dysmenorrhea and dysuria compared to those without migraine.
REPRODUCTIVE BIOMEDICINE ONLINE
(2023)
Review
Clinical Neurology
Dilara Onan, Samaira Younis, William David Wellsgatnik, Fatemeh Farham, Saulius Andruskevicius, Ana Abashidze, Asel Jusupova, Yuriy Romanenko, Oxana Grosu, Meerimgul Zamirbekovna Moldokulova, Ulkar Mursalova, Saida Saidkhodjaeva, Paolo Martelletti, Sait Ashina
Summary: This article explores the similarities and differences in the pathophysiology, epidemiology, burden and disability, comorbidities, and responses to treatments between tension-type headache (TTH) and migraine. Distinguishing between the two in clinical practice and research is challenging due to the lack of specific diagnostic tests and biomarkers. The article also discusses future research directions to address diagnostic challenges and improve the understanding and management of these conditions.
JOURNAL OF HEADACHE AND PAIN
(2023)
Review
Otorhinolaryngology
Bernichi J.v, Rizzo V.l, Villa J.f, Santos R.f, Caparroz F.a.
Summary: Headache, a common symptom, has often been attributed to anatomical abnormalities of the nose and paranasal sinuses. However, many cases diagnosed as sinus headaches are actually misdiagnosed, leading to negative impacts on patient quality of life. Otolaryngologists should establish a direct and precise diagnosis based on clinical history, nasal endoscopy, and occasional CT scan to reduce misdiagnosis probability.
AMERICAN JOURNAL OF OTOLARYNGOLOGY
(2021)
Article
Anesthesiology
Hsiangkuo Yuan, Samantha Strutner, Clara Yuh, Suwarna Anand, Gaurav Chauhan, Anand Prem, Shalini Shah, Nathaniel M. Schuster
Summary: With headache being a common complaint, accurately diagnosing and treating specific headache disorders requires understanding and differentiating various headache characteristics. This article discusses several myths about common headache disorders and provides a discussion based on the International Classification of Headache Disorders and the latest studies. Understanding the intricacies of headache diagnoses helps providers provide better care for patients.
REGIONAL ANESTHESIA AND PAIN MEDICINE
(2023)
Article
Clinical Neurology
Richard B. Lipton, Robert A. Nicholson, Michael L. Reed, Andre B. Araujo, Dena H. Jaffe, Douglas E. Faries, Dawn C. Buse, Robert E. Shapiro, Sait Ashina, M. Janelle Cambron-Mellott, John C. Rowland, Eric M. Pearlman
Summary: The OVERCOME (US) 2018 study revealed slow but steady progress in the diagnosis and preventive treatment of migraines, but many patients still have unmet needs in terms of consulting, diagnosis, and treatment. Additionally, there are varying unmet needs within the category of episodic migraines.
Article
Medicine, General & Internal
Melissa McNeil
Summary: Headaches are common in primary care practices, with tension-type headaches and migraine headaches being the most prevalent. Imaging is generally unnecessary unless concerning findings are identified. The principles of acute treatment include early initiation of therapy and adequate dosing to avoid medication overuse headaches.
MEDICAL CLINICS OF NORTH AMERICA
(2021)
Article
Clinical Neurology
Marte H. Bjork, Solveig Borkenhagen, Francisco Oteiza, Aud N. Dueland, Frank E. Sorgaard, Erik Magnus Saether, Christoffer Bugge
Summary: The study found a favorable effect of CGRPabs, amitriptyline, and simvastatin compared with beta blockers, while topiramate and clonidine were associated with poorer outcomes. Patients on simvastatin, CGRPabs, and amitriptyline were more likely to achieve a clinically significant reduction in triptan use during the first 90 days of treatment.
EUROPEAN JOURNAL OF NEUROLOGY
(2023)
Article
Clinical Neurology
Huanxian Liu, Ming Dong, Kaiming Liu, Zhihua Jia, Wei Gui, Yingying Cheng, Yudan Lv, Kang Qu, Hongru Zhao, Jianjun Chen, Dan Zhang, Zhiliang Fan, Xiaosu Yang, Dongmei Hu, Hongyan Xie, Mingxin Li, Bing Wen, Sufen Chen, Peng Xu, Qingqing Rong, Qiu He, Zhanxiu Ren, Fanhong Yan, Heling Zhao, Min Chen, Tingmin Yu, Hongli Qu, Xingkai An, Huailian Guo, Xinhua Zhang, Xiaoping Pan, Xiaojuan Wang, Shi Qiu, Lvming Zhang, Hongling Zhao, Xin Pan, Qi Wan, Lanyun Yan, Jing Liu, Zhe Yu, Mingjie Zhang, Ye Ran, Xun Han, Shengyuan Yu, Zhao Dong
Summary: Misdiagnosis and inadequate treatment of primary headache disorders in China remain significant challenges, with over half of the patients remaining undiagnosed and most of them not receiving preventive medication. More focused efforts are needed to improve the diagnosis and preventive treatment measures for primary headache disorders in the future.
JOURNAL OF HEADACHE AND PAIN
(2023)
Article
Clinical Neurology
Arife Cimen Atalar, Aynur Ozge, Bengi Gul Turk, Esme Ekizoglu, Duygu Kurt Gok, Betul Baykan, Semih Ayta, Fusun Ferda Erdogan, Seher Naz Yeni, Bahar Tasdelen, Sibel K. Velioglu
Summary: In this study, the diagnostic gaps in the diagnosis of comorbid migraine without aura (MwoA) in patients with idiopathic/genetic epilepsy (I/GE) were disclosed using a zone concept. Longer headache duration, throbbing pain, increase of pain by physical activity, photophobia and/or phonophobia, presence of vertigo/dizziness, osmophobia, and higher VAS scores were found to be the main associated factors for the comorbid MwoA diagnosis in patients with I/GEs.
FRONTIERS IN NEUROLOGY
(2023)