Article
Biochemistry & Molecular Biology
Bartlomiej Dabrowski, Agnieszka Zuchowska, Artur Kasprzak, Grazyna Zofia Zukowska, Zbigniew Brzozka
Summary: Graphene oxide has potential applications in biomedicine, particularly as a drug carrier, due to its high surface area and functionalization capabilities. However, the internalization of graphene oxide inside mammalian cells is not well understood. Factors such as particle size and surface modifications can affect the cellular uptake of graphene oxide. Additionally, interaction with biological fluids can alter its biological properties. This study investigated the effect of graphene oxide particle size on internalization efficiency and the impact of serum components on its structure and interaction with cells.
CHEMICO-BIOLOGICAL INTERACTIONS
(2023)
Article
Engineering, Chemical
Xue Zhang, Lingyi Li, Dadong Shao
Summary: In this study, a novel polyoxometalate modified ammoniated graphene oxide (PHGO) was synthesized and found to be an effective adsorbent for removing U(VI) from radioactive wastewater. PHGO exhibited a high efficiency in U(VI) removal and showed good stability.
SEPARATION AND PURIFICATION TECHNOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Kyu Ha Lee, Ji Young Chu, Ae Rhan Kim, Dong Jin Yoo
Summary: A series of novel anion-exchange composite membranes with improved ion conductivity and alkaline stability were prepared in this study, providing a new strategy for potential application of AEMFCs.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2021)
Article
Chemistry, Multidisciplinary
Jeff W. M. Bulte, Chao Wang, Ali Shakeri-Zadeh
Summary: Superparamagnetic iron oxide (SPIO)-labeling of cells for magnetic resonance imaging (MRI) cell tracking has a long history, but studies have shown that the labeled cells may have different behaviors compared to unlabeled cells. With the emergence of magnetic particle imaging (MPI) cell tracking, there has been a renaissance in the formulation of SPIO nanoparticles optimized for MPI. Lessons learned from past experiences with SPIO-labeling for MRI could potentially facilitate the clinical translation of (combined) MRI/MPI cell tracking.
ADVANCED FUNCTIONAL MATERIALS
(2022)
Article
Engineering, Biomedical
Florina Veider, Patrick Knoll, Arne Matteo Joergensen, Daniel Stengel, Andreas Bernkop-Schnuerch
Summary: This study investigated the impact of the mucus gel barrier on the uptake of lipid-based nanocarriers by intestinal cells. Different surfactant-based nanoemulsions were developed and assessed. The results showed that zwitterionic and polyglycerol nanocarriers had similar mucus permeation properties as polyethylene glycol nanocarriers, but they exhibited higher cellular uptake. These findings suggest that zwitterionic and polyglycerol nanocarriers have the potential to overcome both the mucus and epithelial barriers of the mucosa.
ACTA BIOMATERIALIA
(2023)
Article
Chemistry, Physical
Wei Zhang, Hao Huang, Roy Bernstein
Summary: Membrane fouling and biofouling are major challenges in wastewater treatment using membrane technology. This study successfully fabricated a dual functionality polyethersulfone ultrafiltration membrane with antifouling and antibiofouling properties, demonstrating its excellent performance and potential for wastewater treatment.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Materials Science, Multidisciplinary
Sohan Bir Singh, Mahuya De
Summary: This study found that the addition of platinum, nickel, and palladium can improve the hydrogen uptake capacity of reduced and exfoliated graphene oxides, but the effect depends on the type of metal and preparation method. Platinum had minimal impact on the structure of graphene oxides, while nickel and palladium additions significantly altered their structural properties.
JOURNAL OF MATERIALS RESEARCH
(2021)
Article
Chemistry, Analytical
Shixin Zhang, Huanqiao Song, Tianjiao Li, Mingsheng Luo, Yu Chen, Changke Shao
Summary: This study reports a facile synthesis of Pt and SnO2 double junction structure graphene catalyst (Pt/SnO2GN) through sol-gel combined with glycol hydrothermal reduction method. The results show that Pt/ SnO2GN has better catalytic performance for ethanol electrooxidation and excellent catalytic stability.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2023)
Article
Construction & Building Technology
Maosen Li, Ren Luo, Lingling Qin, Huai Liu, Ping Duan, Wu Jing, Zuhua Zhang, Xinhao Liu
Summary: The research introduced graphene oxide (GO) to improve the thermal stability of metakaolin (MK) based geopolymer. Results showed that the addition of well-dispersed GO can effectively prevent cracks in geopolymer caused by high temperature, thus enhancing its strength under high temperature conditions.
CEMENT & CONCRETE COMPOSITES
(2022)
Article
Chemistry, Multidisciplinary
Jiulong Li, Xiang Wang, Kuo-Ching Mei, Chong Hyun Chang, Jinhong Jiang, Xiangsheng Liu, Qi Liu, Linda M. Guiney, Mark C. Hersam, Yu-Pei Liao, Huan Meng, Tian Xia
Summary: Graphene oxide (GO) as a two-dimensional nanomaterial shows high potential in biomedical applications, with its toxicity in liver cells mainly dependent on lateral size, inducing strong effects in Kupffer cells while showing lower toxicity in liver sinusoidal endothelial cells and hepatocytes.
Article
Chemistry, Physical
Lijun Chen, Zhipeng Yin, Sikai Mei, Xunwen Xiao, Hai-Qiao Wang
Summary: Zwitterionic molecules are utilized to modify the ZnO cathode interlayer in inverted CsPbI2Br perovskite solar cells, passivating defects at the interface of CsPbI2Br/ZnO and improving electron extraction efficiency. This results in enhanced charge transfer, suppressed charge recombination, and desirable energy level alignment at the cathode contact, leading to superior optoelectronic device performance and stability. Additionally, the champion efficiency is significantly improved with V-OC up to 1.25 V and FF of 76.83%, while the optimized device maintains around 80% of its initial efficiency for 32 days under illumination and 18 days stored in ambient air.
JOURNAL OF POWER SOURCES
(2021)
Article
Chemistry, Physical
Soheyla Karimi, Hassan Namazi
Summary: The study successfully fabricated a triazine dendrimer-functionalized graphene oxide nanocarrier for drug delivery systems with potential applications in cancer treatment. The results showed that the nanocarrier exhibited pH-responsive drug release behavior, excellent biocompatibility, and higher apoptotic effects on breast cancer cells.
JOURNAL OF ALLOYS AND COMPOUNDS
(2021)
Article
Nanoscience & Nanotechnology
Krupa Kansara, Ramesh Singh, Pankaj Yadav, Abdulkhalik Mansuri, Ashutosh Kumar, Dhiraj Bhatia
Summary: This study explores the conjugation of cationic lipid DOTMA and DNA tetrahedron nanostructure (TdN) and evaluates their enhanced uptake, stability, bioimaging, and biotherapeutic potential in cells and zebrafish eleutheroembryos. The research highlights the future biomedical applications of the TdN-DOTMA conjugate in drug delivery, bioimaging, biosensing, and therapeutics.
ACS APPLIED NANO MATERIALS
(2023)
Article
Biochemical Research Methods
Takashi Shimomura, Ryo Seino, Kaori Umezaki, Asako Shimoda, Takatoshi Ezoe, Munetaka Ishiyama, Kazunari Akiyoshi
Summary: Novel extracellular vesicular-membrane-binding fluorescent probes, Mem dye-Green, Mem dye-Red, and Mem dye-Deep Red, have been developed for monitoring EV uptake into cells. These dyes enable highly sensitive fluorescence imaging of EVs and can be used to observe EV dynamics in live cells, showing excellent EV labeling performance without aggregation and minimal particle enlargement.
BIOCONJUGATE CHEMISTRY
(2021)
Article
Biophysics
Monica Notarbartolo, Marina Massaro, Raquel de Melo Barbosa, Carlotta Emili, Leonarda Francesca Liotta, Paola Poma, Francisco M. Raymo, Rita Sanchez-Espejo, Riccardo Vago, Cesar Viseras-Iborra, Serena Riela
Summary: In recent years, there has been an increasing use of clay minerals in the pharmaceutical field. This study investigates the cellular uptake mechanisms of hectorite (Ht), a clay mineral with potential applications as a drug carrier. The study also explores the concept of covalently grafting the anticancer molecule methotrexate (MTX) onto Ht to form a nanomaterial. The results demonstrate the potential of Ht as a promising material for anticancer therapy.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)