Delayed emergence of subdiffraction-sized mutant huntingtin fibrils following inclusion body formation

Super-Resolution Fluorescence of Huntingtin Reveals Growth of Globular Species into Short Fibers and Coexistence of Distinct Aggregates

(2014) Whitney C. Duim et al.   ACS Chemical Biology

Aggregation Behavior of Chemically Synthesized, Full-Length Huntingtin Exon1

(2014) Bankanidhi Sahoo et al.   BIOCHEMISTRY

Biophysical Underpinnings of the Repeat Length Dependence of Polyglutamine Amyloid Formation

(2014) Elizabeth Landrum et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Super-resolution fluorescence imaging with single molecules

(2013) Steffen J Sahl et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

d-Polyglutamine Amyloid Recruits l-Polyglutamine Monomers and Kills Cells

(2013) Karunakar Kar et al.   JOURNAL OF MOLECULAR BIOLOGY

Exogenous delivery of chaperonin subunit fragment ApiCCT1 modulates mutant Huntingtin cellular phenotypes

(2013) E. M. Sontag et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease

(2013) K. Sathasivam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fibrillar α-Synuclein and Huntingtin Exon 1 Assemblies Are Toxic to the Cells

(2012) Laura Pieri et al.   BIOPHYSICAL JOURNAL

Nanoscopy in a Living Mouse Brain

(2012) S. Berning et al.   SCIENCE

Sub-Diffraction Imaging of Huntingtin Protein Aggregates by Fluorescence Blink-Microscopy and Atomic Force Microscopy

(2011) Whitney C. Duim et al.   CHEMPHYSCHEM

A Two-Step Path to Inclusion Formation of Huntingtin Peptides Revealed by Number and Brightness Analysis

(2010) Giulia Ossato et al.   BIOPHYSICAL JOURNAL

Mutant Huntingtin Fragments Form Oligomers in a Polyglutamine Length-dependent Mannerin Vitroandin Vivo

(2010) Justin Legleiter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Huntington's disease: from molecular pathogenesis to clinical treatment

(2010) Christopher A Ross et al.   LANCET NEUROLOGY

Real-time computation of subdiffraction-resolution fluorescence images

(2009) S. WOLTER et al.   JOURNAL OF MICROSCOPY

Polyglutamine disruption of the huntingtin exon 1 N terminus triggers a complex aggregation mechanism

(2009) Ashwani K Thakur et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mutant huntingtin activates Nrf2-responsive genes and impairs dopamine synthesis in a PC12 model of Huntington's disease

(2008) Willeke MC van Roon-Mom et al.   BMC MOLECULAR BIOLOGY

Super-resolution imaging in live Caulobacter crescentus cells using photoswitchable EYFP

(2008) Julie S Biteen et al.   NATURE METHODS

Mapping the Number of Molecules and Brightness in the Laser Scanning Microscope

(2007) Michelle A. Digman et al.   BIOPHYSICAL JOURNAL