期刊
LANGMUIR
卷 29, 期 32, 页码 9958-9961出版社
AMER CHEMICAL SOC
DOI: 10.1021/la401288g
关键词
-
资金
- U.S. DOE, Office of BES, Division of Materials Science and Engineering
- U.S. Department of Energy's National Nuclear Security Administration [DE-AC04-94AL85000]
The characterization of liposomes was undertaken using in-situ microfluidic transmission electron microscopy. Liposomes were imaged without contrast enhancement staining or cryogenic treatment, allowing for the observation of functional liposomes in an aqueous environment. The stability and quality of the liposome structures observed were found to be highly dependent on the surface and liposome chemistries within the liquid cell. The successful imaging of liposomes suggests the potential for the extension of in-situ microfluidic TEM to a wide variety of other biological and soft matter systems and processes.
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