Article
Engineering, Biomedical
Lorenzo Degli Esposti, Alessio Adamiano, Dritan Siliqi, Cinzia Giannini, Michele Iafisco
Summary: The study found that hydroxycitrate inhibits hydroxyapatite crystallization more effectively than citrate, while glutarate leads to the formation of different morphologies of nanoparticles. The central carboxyl group of citrate is involved in the selective binding with the hydroxyapatite crystal surface and regulating crystal growth.
BIOACTIVE MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Liang Ding, Jinxiang Zeng, Muzhong Luo, Jian Zhou
Summary: Statherin (SN) is an important protein that can adsorb on enamel to maintain calcium ions balance and promote biomineralization. This study found that SN can adsorb on the hydroxyapatite (HAP) surface, but its conformation and activity change depending on the solution. Furthermore, SN can stabilize calcium and phosphorus clusters, preventing the dissolution of hydroxyapatite and the precipitation of calcium phosphate.
ADVANCED MATERIALS INTERFACES
(2022)
Article
Nanoscience & Nanotechnology
Alexander L. Danesi, Dimitra Athanasiadou, Abdulmateen O. Aderinto, Prakash Rasie, Leo Y. T. Chou, Karina M. M. Carneiro
Summary: The study demonstrates that DNA nanostructures can promote site-specific calcium phosphate formation under mineralizing conditions, resulting in amorphous calcium phosphate or hydroxyapatite. This finding sheds light on the mechanisms of crystal nucleation and growth in mineralized tissues, providing insights for mineralized tissue regeneration strategies.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Biophysics
C. R. Akshata, G. Harichandran, E. Murugan
Summary: The plant polysaccharide pectin, which is chemically similar to bone extracellular matrix (ECM), has been found to promote the crystallization of strontium-substituted hydroxyapatite (HA). Pectin has a preferential affinity for strontium over calcium, resulting in the incorporation of strontium in apatite, reduced crystal size, and retention of more pectin residues.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2023)
Article
Spectroscopy
Joanna Szczuka, Mariusz Sandomierski, Tomasz Buchwald
Summary: The main objective of the research is to improve the bonding of hydroxyapatite (HA) on the surface of titanium alloy, with a focus on the role of octadecylphosphonic acid (ODPA). The results show that ODPA can increase the precipitation of HA, while adding ODPA to annealed titanium alloy restricts the precipitation of HA on its surface.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Materials Science, Multidisciplinary
Durga Bhakta Pokharel, Liping Wu, Junhua Dong, Xin Wei, Ini-Ibehe Nabuk Etim, Dhruba Babu Subedi, Aniefiok Joseph Umoh, Wei Ke
Summary: The study investigated the effect of adding D-fructose to simulated body fluid on the corrosion behavior of AZ31 magnesium alloy. The results showed that the addition of fructose enhanced the deposition of phosphates, forming thick and compact corrosion products, and significantly improved the corrosion resistance of the alloy in the simulated body fluid.
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Lucas Fabricio Bahia Nogueira, Marcos Antonio Eufrasio Cruz, Guilherme Jose Aguilar, Delia Rita Tapia-Blacido, Marcia Eliana da Silva Ferreira, Bianca Chieregato Maniglia, Massimo Bottini, Pietro Ciancaglini, Ana Paula Ramos
Summary: Inspired by collagen fibrils, this study compares two methods to synthesize bioactive hybrid membranes and assesses the role of the organic matrix in mineral phase deposition. The hybrid membranes have uniform mineral particle dispersion and enhanced mechanical properties. They are bioactive, non-toxic to osteoblasts, and display antibacterial action against pathogenic microorganisms. These findings have potential for developing bioactive hybrid membranes with controllable degradation rates and antimicrobial properties.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Nanoscience & Nanotechnology
Kefeng Wang, Fengxiong Luo, Ling Wang, Boqing Zhang, Yujiang Fan, Xin Wang, Dingguo Xu, Xingdong Zhang
Summary: Calcium and phosphate ions play crucial roles in biomineralization, with phosphate ions being more important. The guanidyl group and surrounding carboxyl terminal groups on proteins may serve as excellent nucleation domains. The distribution of acidic/basic residues on proteins promotes the formation of large Ca and P ions clusters.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Polymer Science
Fiorella Ortiz, Antonio Diaz-Barrios, Zoraya E. Lopez-Cabana, Gema Gonzalez
Summary: Collagen/hydroxyapatite hybrids show promise as biomimetic materials for bone tissue replacement. The biomineralization process was achieved through a double diffusion system, where an electric field was applied to promote ion migration and form hydroxyapatite on collagen membranes. The results of this study provide valuable insights for manufacturing biomimetic bone-like materials.
Article
Biochemistry & Molecular Biology
Hossam Donya, Reem Darwesh, M. K. Ahmed
Summary: Different nanocomposites were encapsulated into nanofibrous scaffolds, with compositions indexed as HAP@PLA, CdSe@PLA, HAP/CdSe@PLA, HAP/GO@PLA, and HAP/CdSe/GO@PLA. Results showed that the addition of CdSe and GO dopants significantly increased nanofiber diameter and enhanced antibacterial activity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Chemistry, Multidisciplinary
Bin Jiang, Xin Li, Bozhi Yang, Shujie Yang, Xinyi Chen, Junhong Chen, Minghao Fang, Zhaohui Huang, Xin Min, Xiaozhi Hu
Summary: The occurrence of fractures is a common injury, and bone reconstruction surgery often uses porous hydroxyapatite materials. This study investigates the formation of apatite crystals within the internal microstructures of the bone implants and reveals differences in properties compared to surface-formed crystals. The findings provide insights into the temporal evolution of biomineralization processes and can contribute to the development of biomimetic implants for tissue engineering applications.
APPLIED SCIENCES-BASEL
(2023)
Article
Chemistry, Multidisciplinary
Chuntao Chen, Jieshu Qian, Hongwei Chen, Heng Zhang, Lei Yang, Xiaohong Jiang, Xuan Zhang, Xiaoyu Li, Jing Ma, Dongping Sun
Summary: Biomineralization in organisms generates hierarchically structured minerals with vital biological functions. The biological secretion of nanocellulose can greatly accelerate nucleation rate, facilitate uniform distribution of crystals, and create composites with higher Young modulus. The biological metabolism conditions allow easier capture of calcium ions for subsequent growth of crystals.
Article
Biochemistry & Molecular Biology
Alexander L. Danesi, Dimitra Athanasiadou, Ahmad Mansouri, Alina Phen, Mehrnoosh Neshatian, James Holcroft, Johan Bonde, Bernhard Ganss, Karina M. M. Carneiro
Summary: Biomineralization is a crucial process in which organisms produce mineralized tissues, such as teeth, bones, and shells, composed of hierarchically organized hydroxyapatite crystals. Developing protein-based materials as artificial scaffolds for guiding hydroxyapatite growth is an attractive goal for designing ordered nanomaterials and tissue regeneration. Uniaxial hydroxyapatite growth on a nanoengineered amelogenin scaffold combined with amelotin may provide insights into the molecular mechanism of hydroxyapatite formation and mineralized tissue formation.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Chemistry, Applied
Lin Shi, Tao Wang, Lei Yang, Chuntao Chen, Ran Dou, Xiaoli Yang, Bianjing Sun, Baojing Zhou, Lei Zhang, Dongping Sun
Summary: By changing the carbon source during the biosynthesis process, we have successfully improved the performance and preparation process of BC/HAp composite, enhancing its potential in biomedical applications such as bone tissue engineering.
CARBOHYDRATE POLYMERS
(2022)
Article
Materials Science, Multidisciplinary
Asma M. Alturki
Summary: Bioceramic compositions based on zirconia/hydroxyapatite modified with silver ions and zirconia nanoparticles were fabricated and characterized. The distribution of zirconia nanoparticles was found to be affected by different treatment methods.
APPLIED PHYSICS A-MATERIALS SCIENCE & PROCESSING
(2021)
Article
Materials Science, Biomaterials
Ryota Domura, Rie Sasaki, Masami Okamoto, Minoru Hirano, Katsunori Kohda, Brett Napiwocki, Lih-Sheng Turng
JOURNAL OF MATERIALS CHEMISTRY B
(2017)
Article
Mechanics
Katsuhisa Tokumitsu, Asuka Hayashi, Sakiko Fukunishi, Kazuhumi Kohno, Masami Okamoto
NIHON REOROJI GAKKAISHI
(2018)
Article
Polymer Science
Konrad Szustakiewicz, Malgorzata Gazinska, Bartlomiej Kryszak, Michal Grzymajlo, Jacek Piglowski, Rafal J. Wiglusz, Masami Okamoto
EUROPEAN POLYMER JOURNAL
(2019)
Correction
Polymer Science
Konrad Szustakiewicz, Malgorzata Gazinska, Bartlomiej Kryszak, Michal Grzymajlo, Jacek Piglowski, Rafal J. Wiglusz, Masami Okamoto
EUROPEAN POLYMER JOURNAL
(2019)
Article
Chemistry, Physical
Joanna Raczkowska, Barbara Orzechowska, Sabina Patryas, Kamil Awsiuk, Andrzej Kubiak, Masaya Kinoshita, Masami Okamoto, Justyna Bobrowska, Tomasz Stachura, Jerzy Soja, Krzysztof Sladek, Malgorzata Lekka
Article
Mechanics
Ryohei Ohta, Masami Okamoto
Summary: Acrylamide copolymer-based gel substrates with different viscoelasticity were used to assess the impact of viscoelasticity on the relationship among cancer stemness, cellular motility, and mesenchymal properties in human breast adenocarcinoma cells. The study found that the substrate damping coefficient was significantly correlated with cellular migration speed and the surface molecule CD44, but was independent of EMT with regard to the stem cell marker CD133 expression. This suggests that substrate damping plays a crucial role in influencing cellular motility, cancer stemness, and EMT induction.
NIHON REOROJI GAKKAISHI
(2021)
Article
Engineering, Chemical
M. Okamoto
Summary: Polymer/layered filler nano-composites (PLFNCs) exhibit improved mechanical properties with low filler loading, but the mechanisms of enhancement effects in nanocomposites are still not fully understood. Nanoscale control and improved understanding of physicochemical phenomena at the nanometer scale contribute to the rapid development of novel PLFNCs.
INTERNATIONAL POLYMER PROCESSING
(2022)
Article
Nanoscience & Nanotechnology
Yuki Okamoto, Masaya Kinoshita, Masami Okamoto
Article
Chemistry, Multidisciplinary
Y. Ishikawa, R. Sasaki, R. Domura, M. Okamoto
MATERIALS TODAY CHEMISTRY
(2019)
Article
Chemistry, Multidisciplinary
M. Kinoshita, Y. Okamoto, M. Furuya, M. Okamoto
MATERIALS TODAY CHEMISTRY
(2019)
Article
Chemistry, Multidisciplinary
R. Sasaki, R. Domura, M. Okamoto
MATERIALS TODAY CHEMISTRY
(2019)
Article
Chemistry, Multidisciplinary
Mitsuru Furuya, Naoki Shimono, Kazuyuki Yamazaki, Ryota Domura, Masami Okamoto
MATERIALS TODAY CHEMISTRY
(2017)
Article
Chemistry, Physical
Yusuke Toyota, Masami Okamoto, Shuichi Arakawa
APPLIED CLAY SCIENCE
(2017)
Article
Engineering, Biomedical
Ryota Domura, Rie Sasaki, Yuma Ishikawa, Masami Okamoto
JOURNAL OF FUNCTIONAL BIOMATERIALS
(2017)
Article
Chemistry, Physical
Yusuke Toyota, Yoko Matsuura, Masashi Ito, Ryota Domura, Masami Okamoto, Shuichi Arakawa, Minoru Hirano, Katsunori Kohda
APPLIED CLAY SCIENCE
(2017)
