Review
Chemistry, Multidisciplinary
Luke J. O'Driscoll, Martin R. Bryce
Summary: Oligo(arylene ethynylene) (OAE) derivatives are key molecules in the field of molecular electronics, known for their ease of synthesis and flexibility in functionalization. This review summarizes the breadth of research on OAE molecular wires, focusing on the structure-property relationships related to their electronic conductance. Additionally, the growing interest in the thermoelectric properties of OAE derivatives and their potential in organic thermoelectric devices is explored.
Article
Chemistry, Multidisciplinary
Peng Liu, Kecheng Quan, Miaomiao Liu, Huaguang Wang, Henny C. van der Mei, Henk J. Busscher, Zexin Zhang
Summary: We have developed a self-cleaning, bacterial killing surface by immobilizing AgCl microparticles, which acts as chemical micropumps. This surface effectively kills attached bacteria and can sustainably remove bacteria through UV-activated micropumping. Our work is significant for the sustainable use of bacterial contact-killing surfaces.
CHEMICAL COMMUNICATIONS
(2022)
Article
Engineering, Biomedical
Jan C. Kwan, Ronald S. Flannagan, Monica Vasquez Pena, David E. E. Heinrichs, David W. W. Holdsworth, Elizabeth R. Gillies
Summary: Infection is a common problem with orthopedic implants due to the development of biofilms on metal substrates. Revision surgery with antibiotic delivery is the standard treatment, but it has drawbacks. This study presents a new approach using induction heating and a temperature-sensitive coating to enable thermally triggered antibiotic release, which effectively reduces bacterial colonization on implants.
ADVANCED HEALTHCARE MATERIALS
(2023)
Article
Chemistry, Physical
Yusuke Hattori, Wakana Matsuda, Shu Seki
Summary: In this study, the investigation of conjugated oligomers with distinct chain lengths revealed a unique solid-solid transition only in the pentamer, resulting in uniaxial expansion in the condensed phase. Time-resolved microwave conductivity measurements highlighted the interplay between thermal activation of charge carriers and uniaxial expansion reducing electronic coupling in pi-stacking of adjacent molecules.
CHEMICAL PHYSICS LETTERS
(2022)
Review
Pharmacology & Pharmacy
Pamela M. Lundin, Briana L. Fiser, Meghan S. Blackledge, Hannah L. Pickett, Abigail L. Copeland
Summary: Bacterial infections caused by biofilms are responsible for 80% of bacterial infections in humans. The use of self-assembled monolayers (SAMs) as a chemical strategy to combat biofilm formation shows promise due to their strong covalent bonds and versatile synthesis. This review focuses on the use of SAMs to inhibit biofilm formation and graft biocidal agents, with potential applications in indwelling medical devices. The challenges and future directions for this field are also discussed.
Article
Biotechnology & Applied Microbiology
Chang Lu, Nian Zhang, Sihoi Kou, Liangliang Gao, Bo Peng, Yunlu Dai, Jun Zheng
Summary: In this research, sanguinarine was shown to act synergistically with various aminoglycosides, effectively potentiating their killing ability on diverse bacterial pathogens. Mechanistic studies revealed elevated intracellular ROS and DNA oxidative levels in cells treated with the combination of sanguinarine and aminoglycosides. Additionally, the presence of aminoglycosides promoted the uptake of sanguinarine and sanguinarine was shown to eliminate persister cells and established biofilm cells both in vivo and in vitro. This study provides a novel approach to reduce the clinical dosages of aminoglycosides.
MICROBIAL BIOTECHNOLOGY
(2022)
Article
Chemistry, Physical
Jiaqi Xu, Zhoulin Ye, Zongcai Deng, Dongchu Chen, Qilang Lin, Dongyang Chen
Summary: Polymer batteries are becoming increasingly popular due to their flexibility, compatibility with organic electrolytes, and environmental friendliness. However, the utilization of redox-active units and the kinetics of electrochemical reactions in the polymer network hinder their development. In this study, two redox-active polymers, MV-TPAEK and 2MV-TPAEK, were prepared by attaching mono- and diviologen functionalities to a poly(arylene ether ketone) backbone. These polymers were then mixed with N-doped carbon nanotubes to create polymer electrodes. The results showed that the 2MV-TPAEK electrode outperformed the MV-TPAEK electrode, delivering higher discharge capacities and maintaining better performance after cycling.
ACS APPLIED ENERGY MATERIALS
(2023)
Article
Materials Science, Biomaterials
Haili Wang, Wei You, Bin Wu, Xuan Nie, Lei Xia, Changhui Wang, Ye-Zi You
Summary: This study developed a new functional material based on silver nanoparticles and phenylboronic acid, showing significantly enhanced antibacterial activity by disrupting bacterial membranes and high selectivity against a variety of bacteria.
JOURNAL OF MATERIALS CHEMISTRY B
(2022)
Article
Chemistry, Multidisciplinary
Jianqing Li, Zijuan Meng, Zeyan Zhuang, Bingnan Wang, Jun Dai, Guangxue Feng, Xiaoding Lou, Fan Xia, Zujin Zhao, Ben Zhong Tang
Summary: The newly designed cationic antibacterial agent beta-PM-PIO shows promising efficacy in treating biofilm-associated infections, with visual diagnostic function and antibiofilm performance, while having less potential for developing drug resistance in multidrug-resistant bacteria.
Article
Electrochemistry
Jiaqi Xu, Zongcai Deng, Bo Wu, Meijin Lin, Dongyang Chen
Summary: Organic polymers with redox-active moieties have gained attention as sustainable, flexible, environmentally benign, and highly stable electrode materials for high-performance rechargeable batteries. By synthesizing viologen functionalized fluorene-containing poly(arylene ether ketone)s (MV-FPAEKs) and using MV-FPAEK-96 with a DF of 96% as the active material for the polymer cathode, it was found that the stability in the electrolyte can be increased while maintaining rechargeability.
ELECTROCHIMICA ACTA
(2022)
Article
Engineering, Chemical
Amirreza Khataee, Hannes Nederstedt, Patric Jannasch, Rakel Wreland Lindstro
Summary: In this study, we synthesized two types of poly(p-terphenylene alkylene)s containing perfluoroalkylsulfonic acid and perfluorophenylsulfonic acid, respectively, through superacid-mediated polyhydroxyalkylations and made proton exchange membranes (PEMs) out of them. Compared to Nafion 212, the PEM with perfluorophenylsulfonic acid groups (PTPF-Phenyl-SA) showed higher ionic conductivity and eight times lower vanadium (IV) permeation rate. The VRFB based on PTPF-Phenyl-SA exhibited longer self-discharge duration, high average coulombic efficiency of 99.6%, and lower capacity fade of 0.24% per cycle compared to Nafion 212.
JOURNAL OF MEMBRANE SCIENCE
(2023)
Article
Chemistry, Physical
Zhiqiang Zhao, Zheng Bian, Yu Chen, Chuanqing Kang, Lianxun Gao, Guangshan Zhu
Summary: The study shows that chiral oligomers can self-assemble into vesicle-like particles in hydrophobic or hydrophilic solvent systems independently of molecular design and chemical environments. The vesicular membranes are likely stabilized by pi-pi stacking interactions between foldamer backbones and collective van der Waals interactions between side chains, as supported by TEM, UV, CD and PXRD data.
Article
Chemistry, Multidisciplinary
Masnun Naher, Elena Gorenskaia, Stephen A. Moggach, Thomas Becker, Richard J. Nichols, Colin J. Lambert, Paul J. Low
Summary: This study presents a convenient two-step, one-pot synthesis of oligo(arylene-ethynylene) (OAE) molecular wires. The method avoids the multi-step preparation and purification of terminal alkynes. The experimental data suggest that the molecular conductance of the wires is better correlated with the nature of the anchor group rather than the degree of aromaticity of the molecular core.
AUSTRALIAN JOURNAL OF CHEMISTRY
(2022)
Article
Materials Science, Multidisciplinary
Xuefu Che, Weiqin Tang, Jianhao Dong, David Aili, Jingshuai Yang
Summary: A new series of poly(arylene piperidinium)-based anion exchange membranes have been proposed for vanadium redox flow batteries, showing high H+ permeability, low vanadium permeability, and high ion selectivity. The VRFB based on these membranes demonstrates high energy efficiency and stability.
SCIENCE CHINA-MATERIALS
(2022)
Article
Engineering, Chemical
Feixiang Gong, Zhitao Fan, Wenke Xia, Meng Zhang, Lei Wang, Xudong Wang, Xinbing Chen
Summary: By adjusting the chemical structures of functional groups, the properties of CardoPES-C-2-R(Cl-) membranes can be readily adjusted, and these membranes exhibit ultrahigh selectivity and stability in DD.
JOURNAL OF MEMBRANE SCIENCE
(2021)
Article
Nanoscience & Nanotechnology
Kemal Kaya, Mohammed Khalil, Benjamin Fetrow, Hugh Fritz, Pradeepkumar Jagadesan, Virginie Bondu, Linnea Ista, Eva Y. Chi, Kirk S. Schanze, David G. Whitten, Alison Kell
Summary: This paper presents a study on a new cationic oligomer that can inactivate SARS-CoV-2 through visible light irradiation. The oligomer shows outstanding performance in killing E. coli bacterial cells and inactivating the virus in a short period of time. The study also suggests that oligomer-coated materials like wipes and filtration substrates can be useful in inactivating bacteria and viruses.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Chemistry, Physical
Yong-Liang Su, Geng-Xin Liu, Luca De Angelis, Ru He, Ammar Al-Sayyed, Kirk S. Schanze, Wen-Hao Hu, Huang Qiu, Michael P. Doyle
Summary: This study demonstrates the efficient generation of functionalized derivatives through photocatalyzed multicomponent reactions using nitrogen aromatic heterocycles, alkenes, and diazo compounds. The reaction shows high functional group tolerance and exacting regioselectivities. Mechanistic studies, including photophysical measurements, provide insights into this radical cascade reaction.
Editorial Material
Chemistry, Multidisciplinary
Krishna N. Ganesh, Marc Hillmyer, David Kaplan, Sebastien Lecommandoux, Jodie L. Lutkenhaus, Stuart Rowan, Kirk Schanze, Shu Wang, Deqing Zhang
Review
Nanoscience & Nanotechnology
Han Sun, Kirk S. Schanze
Summary: This article comprehensively reviews the synthetic chemistries used to covalently link biofunctional groups onto water-soluble conjugated polymer platforms, including different types of backbones. It also discusses the applications and challenges of functionalized conjugated polymers.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Editorial Material
Nanoscience & Nanotechnology
Cong Li, Chunhai Fan, Kirk S. Schanze, Laura Fernandez
ACS APPLIED MATERIALS & INTERFACES
(2023)
Editorial Material
Nanoscience & Nanotechnology
Kirk Schanze, Christy L. Haynes, Kirk S. Schanze, Laura E. Fernandez
ACS APPLIED MATERIALS & INTERFACES
(2023)
Editorial Material
Chemistry, Multidisciplinary
Jillian M. Buriak, Deji Akinwande, Natalie Artzi, C. Jeffrey Brinker, Cynthia Burrows, Warren C. W. Chan, Chunying Chen, Xiaodong Chen, Manish Chhowalla, Lifeng Chi, William Chueh, Cathleen M. Crudden, Dino Di Carlo, Sharon C. Glotzer, Mark C. Hersam, Dean Ho, Tony Y. Hu, Jiaxing Huang, Ali Javey, Prashant V. Kamat, Il-Doo Kim, Nicholas A. Kotov, T. Randall Lee, Young Hee Lee, Yan Li, Luis M. Liz-Marzan, Paul Mulvaney, Prineha Narang, Peter Nordlander, Rahmi Oklu, Wolfgang J. Parak, Andrey L. Rogach, Mathieu Salanne, Paolo Samori, Raymond E. Schaak, Kirk S. Schanze, Tsuyoshi Sekitani, Sara Skrabalak, Ajay K. Sood, Ilja K. Voets, Shu Wang, Shutao Wang, Andrew T. S. Wee, Jinhua Ye
Article
Chemistry, Physical
Shorooq A. Alomar, Luis Gutierrez-Arzaluz, Issatay Nadinov, Ru He, Xiaodan Wang, Jian-Xin Wang, Jiangtao Jia, Osama Shekhah, Mohamed Eddaoudi, Husam N. Alshareef, Kirk S. Schanze, Omar F. Mohammed
Summary: Structural modifications to molecular systems that control photon emission processes are crucial for the development of fluorescence sensors, X-ray imaging scintillators, and OLEDs. This study explored the effects of slight changes in chemical structure on interfacial excited-state transfer processes using two donor-acceptor systems. The results showed efficient energy transfer in the SDZ-TADF system and both energy and electron transfer processes in the Ac-SDZ-TADF system. Transient absorption measurements and TD-DFT calculations confirmed the occurrence of photoinduced electron transfer in the Ac-SDZ-TADF system. This work provides a straightforward approach to modulate excited-state energy/charge transfer processes at donor-acceptor interfaces.
JOURNAL OF PHYSICAL CHEMISTRY B
(2023)
Article
Biochemistry & Molecular Biology
Zhiliang Li, Charles J. Zeman, Silvano Valandro, Jose Paolo O. Bantang, Kirk S. Schanze
Summary: Non-covalent interactions are widely used in supramolecular chemistry to create nanoscale structures. However, the biomimetic self-assembly and reversibility of diverse nanostructures induced by different important biomolecules in aqueous solution remain challenging.
Article
Chemistry, Multidisciplinary
Taemin Park, Minwoo Han, Kirk S. S. Schanze, Seoung Ho Lee
Summary: We developed a fluorescence sensing strategy based on a self-assembled amphiphilic pyrene/protamine complex system for sensitive and selective detection of trypsin in human urine, which is important for evaluating pancreatic disease. The fluorescence of functionalized pyrene aggregates in aqueous solution was quenched by protamine, but this quenched fluorescence could be recovered by the enzymatic reaction of trypsin. This sensing platform successfully detected trypsin at low concentrations and screened for trypsin inhibitors in non-pretreated human urine.
Article
Nanoscience & Nanotechnology
Michael D. Turlington, Habtom B. Gobeze, Muhammed Younus, Kirk S. Schanze
Summary: A study on the wavelength-dependent interfacial electron transfer mechanisms of diblock oligomers containing oligothiophene and 4,7-di(thiophen-2-yl)benzo[c][1,2,5]thiadizole segments anchored to mesoporous TiO2 films was conducted. It was found that the injection pathway and recombination pathway were influenced by the excitation wavelength and the bridging unit between the blocks. Control over hole localization in the electron transfer process could be achieved by varying the excitation wavelength.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Editorial Material
Engineering, Electrical & Electronic
Hyun Jae Kim, Kirk Schanze, Chengmei Zhong
ACS APPLIED ELECTRONIC MATERIALS
(2023)
Article
Chemistry, Physical
Habtom B. Gobeze, Pradeepkumar Jagadesan, Kirk S. Schanze
Summary: This paper investigates the electronic structure and photophysical properties of two diblock π-conjugated oligomers with electron rich tetra(thiophene) (T4) or octa(thiophene) (T8) segments linked to an electron poor 4,7-bis(2-thienyl)-2,1,3-benzothiadiazole (TBT) moiety. The results show that the diblock oligomers display redox and absorption features that can be attributed to the Tn and TBT units, and the frontier orbitals on the diblock oligomers retain characteristics of the individual π-conjugated segments. Moreover, the fluorescence and transient absorption spectroscopy reveal that the photophysical properties and dynamics of the excited states are dominated by charge transfer between the oligo-thiophene and TBT units.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2023)
Article
Chemistry, Inorganic & Nuclear
Amran A. T. Khan, Habtom B. Gobeze, Tanjila Islam, Hadi D. Arman, Kirk S. Schanze
Summary: This study investigates the effect of bromine substitution on the trans-(NHC)(2)Pt-II(CC-Ar)(2) chromophore through photophysical studies. The results show that the mono-bromo complex has lower emission quantum yield and lifetime, attributed to a larger non-radiative decay rate.
DALTON TRANSACTIONS
(2023)
Article
Nanoscience & Nanotechnology
Kemal Kaya, Mohammed Khalil, Benjamin Fetrow, Hugh Fritz, Pradeepkumar Jagadesan, Virginie Bondu, Linnea Ista, Eva Y. Chi, Kirk S. Schanze, David G. Whitten, Alison Kell
Summary: This study presents a new cationic oligomer that can inactivate SARS-CoV-2 through visible light irradiation. The oligomer shows excellent performance in killing E. coli bacterial cells and inactivating the virus. The introduction of cationic N-methyl imidazolium groups enhances the light activation process but reduces the killing effect on bacteria.
ACS APPLIED MATERIALS & INTERFACES
(2022)