Article
Chemistry, Multidisciplinary
Wei Zhan, Ziwei Liu, Shaokun Jiang, Chunying Zhu, Youguang Ma, Taotao Fu
Summary: In this study, the generation processes of bubbles and droplets in a step-emulsification microfluidic device are compared to show the similarities and differences in the emulsification process. By changing the placement of the microdevice, the effects of buoyancy and gravity on the generation of bubbles and droplets are introduced, and the feedback mechanism of the bubble layer and the effect of droplet accumulation on the emulsification process are clarified.
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2022)
Article
Engineering, Chemical
Ziwei Liu, Xiyang Liu, Shaokun Jiang, Chunying Zhu, Youguang Ma, Taotao Fu
Summary: This study investigated the application of Y step emulsification technology in microfluidic devices, focusing on the influences of microdevice structures and fluid physical properties on droplet generation. Important factors affecting emulsion flux were identified, and a prediction equation for droplet size was proposed based on inertial and viscous forces of the dispersed phase.
CHEMICAL ENGINEERING SCIENCE
(2021)
Article
Chemistry, Multidisciplinary
Xiangke Li, Shi-Yang Tang, Yang Zhang, Jiayuan Zhu, Helen Forgham, Chun-Xia Zhao, Cheng Zhang, Thomas P. Davis, Ruirui Qiao
Summary: Droplet-based microfluidics is a significant technology that can be improved by using fluoropolymer-based surfactants to enhance stability and biocompatibility.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Analytical
Thomas Weber, Sundar Hengoju, Ashkan Samimi, Martin Roth, Miguel Tovar, Miriam A. Rosenbaum
Summary: Microfluidic emulsion-based droplet systems have the potential for inexpensive and high-throughput experimentation. However, selecting and amplifying single droplets of interest from a large number of other droplets is still a challenge. To overcome this limitation, a system is presented where droplets of interest are collected and positioned on agar surface or microtiter plate. Results show effective isolation of single droplets, allowing for further analysis and processing.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Nanoscience & Nanotechnology
Weihao Li, Wuyang Zhuge, Youwei Jiang, Kyle Jiang, Jun Ding, Xing Cheng
Summary: This research introduces an innovative hybrid pumping system that integrates a wirelessly controlled micropump with a 3D-printed modular microfluidic low-pass-filter, offering a portable and stable flow source for microfluidic applications. The experimental results demonstrate highly stabilized flow rate and comparable versatility to bulky commercial pumping systems.
MICROFLUIDICS AND NANOFLUIDICS
(2023)
Article
Engineering, Chemical
Yue Lu, Xuyun Liu, Xiangdong Liu, Yongping Chen
Summary: The droplet generation process in the microfluidic step emulsification chip with a triangular nozzle (SE-T) was studied through visualization experiments and numerical simulations, compared to a rectangular nozzle (SE-R). Different flow regimes, including dripping, dripping-jetting transition, and jetting, were observed in SE-T, with dripping being the preferred regime for generating monodisperse droplets. The larger space and expanding structure of the triangular nozzle in SE-T enhanced the wall wetting effects, leading to earlier appearance and faster neck shrinking. Consequently, SE-T showed more robust droplet performance, producing droplets with consistent size and higher monodispersity, regardless of variations in surfactant concentrations and dispersed phase flow rates.
Review
Polymer Science
Mohamad Orabi, Joe F. Lo
Summary: Hydrogel droplets are biodegradable and biocompatible materials with promising applications in tissue engineering and clinical treatments. Microfluidic techniques provide precise control over the generation of hydrogel droplets, resulting in tight distributions of particle size, shape, matrix, and mechanical properties. This review focuses on recent advances in microfluidic hydrogel droplet generation and the applications of hydrogels in cell and tissue engineering.
Article
Computer Science, Information Systems
Rauno Joemaa, Nafisat Gyimah, Kanwal Ashraf, Kaiser Parnamets, Alexander Zaft, Ott Scheler, Toomas Rang, Tamas Pardy
Summary: Droplet microfluidics allows for the study of large cell populations in chemical isolation at a single-cell resolution. However, current systems rely on manual tuning and customization, limiting reproducibility. In this study, we propose an integrated, modular system for automated droplet generation with high monodispersity, providing dynamic feedback control and wireless communication. Experimental evaluations demonstrate the system's improved performance and reliability compared to existing methods.
Article
Thermodynamics
Yue Ma, Huang Zhang, Qianfeng Liu
Summary: This study experimentally investigates the spreading and splashing behavior of continuous droplets impinging on a heated wall under different conditions. The spreading parameters of the droplets and the relationship between splashing parameters, droplet Weber numbers, and Jacob numbers are analyzed and mathematically fitted.
INTERNATIONAL JOURNAL OF HEAT AND MASS TRANSFER
(2022)
Article
Nanoscience & Nanotechnology
Yiying Wang, Yuman Dong, Huanyu Liu, Wei Yin, Ting Guo, Hao Yuan, Tao Meng
Summary: Compartmentalized droplet bioreactors with selectively permeable interfaces can enhance reaction conversion rates, and microfluidic droplet clusters exhibit improved reaction rates compared to non-microfluidic reactors.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Nanoscience & Nanotechnology
Yuto Takagi, Yutaka Kazoe, Takehiko Kitamori
Summary: A microfluidic device utilizing two-step flow focusing with air flows was developed to generate femtoliter liquid droplets with size and trajectory control. The instability of the gas-liquid interface was identified as the key factor in femtoliter droplet generation. The method has the potential to generate droplets as small as 123 fL in size, making it suitable for various applications including the transport of femtoliter samples from nanofluidic devices to analytical instruments.
MICROFLUIDICS AND NANOFLUIDICS
(2021)
Article
Nanoscience & Nanotechnology
Tristan Gilet, Stephanie van Loo
Summary: In this study, the interaction between microfluidic droplets and pneumatic valves in droplet arrays was investigated experimentally and theoretically. Two main trapping modes were characterized, and the significant increase of hydrodynamic resistance induced by the droplet/valve interaction was quantified. Transitions between trapped and non-trapped regimes were rationalized using a generic theoretical model.
MICROFLUIDICS AND NANOFLUIDICS
(2022)
Article
Chemistry, Analytical
Johnson Q. Cui, Binbin Cui, Frank X. Liu, Yuan Lin, Shuhuai Yao
Summary: This study develops a multiplexable injector for precise injection and encoding of droplet ingredients, allowing for the identification and tracking of color-coded droplets. The developed platform is versatile, compact, and easy to integrate, making it potentially useful in various applications.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Engineering, Environmental
Damian Zaremba, Slawomir Blonski, Piotr M. Korczyk
Summary: This study introduces a novel microfluidic system that can generate the required reagent concentration in a single droplet or produce a sequence of droplets with a specified periodic distribution of concentrations. Digital algorithms are used to ensure superior precision, repeatability, and flexibility in concentration setting through simple operations such as merging and splitting droplets. Unlike traditional Digital microfluidic (DMF) systems, this system is based on channel-based microfluidics operated by programmable syringe pumps, making it easy to integrate with other microfluidic networks.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Chemistry, Analytical
Xiao Zhou, Yuanhang Mao, Miao Gu, Zhen Cheng
Summary: Researchers developed a microfluidic system embedded with a weakly supervised cell counting network (WSCNet) to generate microfluidic droplets, evaluate their quality, and accurately recognize the locations of encapsulated cells.
Article
Materials Science, Multidisciplinary
Syed Mohammad Abid Hasan, Nishir Mehta, Robin L. McCarley, Michael M. Khonsari, Manas Ranjan Gartia
Article
Multidisciplinary Sciences
Moo-Yeon Lee, Namwon Kim, Jae-Hyeong Seo, Mahesh Suresh Patil
Article
Chemistry, Multidisciplinary
Emad Jafari Nodoushan, Young Ju Lee, Hae-Joong Na, Byoung-Hee You, Moo-Yeon Lee, Namwon Kim
Summary: The addition of NaCl reduces the viscosity of wormlike micellar solutions, leading to the formation of branch points that result in shorter relaxation times and lower zero-shear viscosity.
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
(2021)
Article
Chemistry, Physical
Prakash Hamal, Visal Subasinghege Don, Huy Nguyenhuu, Jeewan C. Ranasinghe, Julia A. Nauman, Robin L. McCarley, Revati Kumar, Louis H. Haber
Summary: A fundamental understanding of the kinetics and thermodynamics of chemical interactions at the phospholipid bilayer interface is crucial for developing potential drug-delivery applications. Molecular dynamics simulations and surface-sensitive second harmonic generation spectroscopy were used to study the molecular adsorption and transport of malachite green at the surface of liposomes in water at different temperatures. The adsorption process is exothermic, leading to increased overall entropy, and molecular transport kinetics are more rapid at higher temperatures, with excellent agreement between experimental and simulation results.
JOURNAL OF PHYSICAL CHEMISTRY B
(2021)
Article
Multidisciplinary Sciences
Kunal Sandip Garud, Seong-Guk Hwang, Taek-Kyu Lim, Namwon Kim, Moo-Yeon Lee
Summary: The improvement in quantitative and qualitative heat transfer performances of working fluids is a trending research topic. The study found that hybrid nanofluids exhibit better first and second law characteristics compared to single-particle nanofluids across all nanoparticle shapes. The hybrid nanofluid with OS-shaped nanoparticles in Al2O3/Cu demonstrates maximum values of performance index and Bejan number at 4.07 and 0.913, respectively.
Article
Chemistry, Physical
Eunji Ji, Min Jung Kim, Jong-Young Lee, Dongchul Sung, Namwon Kim, Jin-Woo Park, Suklyun Hong, Gwan-Hyoung Lee
Summary: The study investigates the influence of substrate conditions on the doping and degradation of graphene, revealing that the hydroxyl groups on the oxygen-plasma-treated SiO2 substrate alter the characteristics of graphene and lead to decreased reactivity and conductivity.Graphene on P-SiO2 exhibits higher reactivity due to doping induced by -OH groups and shows reduced carrier mobility and larger shift of charge neutral point. Meanwhile, the device on the bare SiO2 shows negligible changes even after UV exposure.
Article
Chemistry, Physical
Md Shamim Mahmud, Akinjuyigbe Alo, Bahador Farshchian, Gwan-Hyoung Lee, Namwon Kim
Summary: Developing a surface modification technique for thermoplastic polymers is of practical importance. In this research, a controllable laser ablation technique was employed to improve the surface wetting property of PMMA. The ablated surface induced controllable capillary driven flows, and the dynamics of these flows were influenced by various factors.
SURFACES AND INTERFACES
(2022)
Article
Chemistry, Physical
Jae Hwan Jeong, Sojung Kang, Namwon Kim, Rakesh Joshi, Gwan-Hyoung Lee
Summary: The covalent functionalization of 2D materials is crucial for improving their electrical, mechanical, and chemical properties. This review discusses various functionalization methods, site selections, synthesis techniques, characterization methods, and proposed solutions.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2022)
Article
Mechanics
Emad Jafari Nodoushan, Young Ju Lee, Gwan-Hyoung Lee, Namwon Kim
Summary: This study investigates the effects of yield stress and shear banding on the fluidic behaviors of cetyltrimethylammonium bromide/sodium salicylate wormlike micellar solutions flowing through a microfluidic planar contraction geometry. The results show that shear banding has an impact on the fluid flow behavior under different conditions.
Article
Engineering, Electrical & Electronic
Jong Hun Kim, Sojung Kang, Jin-Woo Park, Eul-Doo Park, Youn-Ki Jun, Jae Yeon Han, Jong Hoon Jung, Namwon Kim, Gwan-Hyoung Lee
Summary: This study demonstrates the impact of carbon film configuration on its properties, showing that changing the sputtering power can control the sp(2)/sp(3) ratio and influence the friction, adhesion, and electrical conductivity of the films. The findings suggest a promising approach for producing carbon films with tailored properties for various applications, including frictionless protection coatings.
ACS APPLIED ELECTRONIC MATERIALS
(2021)
Meeting Abstract
Chemistry, Multidisciplinary
Chris Sumner, Robin McCarley
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2019)
Meeting Abstract
Chemistry, Multidisciplinary
Robin McCarley
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2019)
Meeting Abstract
Chemistry, Multidisciplinary
Amanda Owen, Robin McCarley
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2019)
Meeting Abstract
Chemistry, Multidisciplinary
Robin McCarley
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2019)
Meeting Abstract
Chemistry, Multidisciplinary
Shaniqua Hayes, Robin McCarley
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2019)