Article
Chemistry, Multidisciplinary
Dongyang Chen, Francisco Tenopala-Carmona, Julius A. Knoeller, Andreas Mischok, David Hall, Subeesh Madayanad Suresh, Tomas Matulaitis, Yoann Olivier, Pierre Nacke, Frank Giesselmann, Sabine Laschat, Malte C. Gather, Eli Zysman-Colman
Summary: The use of TADF emitters and emitters with preferential horizontal TDM orientation are two emerging strategies to enhance OLED efficiency. In this study, a liquid crystalline MR-TADF emitter, DiKTa-LC, was introduced. The spin-coated film of DiKTa-LC exhibited a preferential horizontal TDM orientation with an anisotropy factor of 0.28. Green-emitting solution-processed OLEDs based on DiKTa-LC achieved an EQE(max) of 13.6%. This study demonstrates how self-assembly of a liquid crystalline TADF emitter can control the orientation of the transition dipole in solution-processed films, which is relevant for high-performance OLEDs.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Multidisciplinary
Yao-Chih Lu, Yu-Tsz Hsu, Tsung-Yen Yang, I-Chun Liou, Sheng-Wei Wang, Po-Chia Huang, Jey-Jau Lee, Long-Li Lai, Hsiu-Fu Hsu
Summary: The introduction of different peripheral substituents can control the mesomorphic behavior of dendrons, with the type and flexibility of the peripheral substituents significantly affecting the mesomorphic range.
Article
Chemistry, Multidisciplinary
Michal Swierczewski, Plinio Maroni, Alexis Chenneviere, Mohammad M. Dadras, Lay-Theng Lee, Thomas Burgi
Summary: The Langmuir-Blodgett technique is used to deposit ultrathin films of Au-38(SC2H4Ph)(24) nanoclusters onto solid surfaces, such as mica and silicon. The morphology of the films transferred at different surface pressures in the mono/bi/trilayer regime is studied using atomic force microscopy. The effect of the time spent on the water surface before deposition on the final ordering of nanoclusters within the network is investigated using fast AFM, X-ray reflectivity, and grazing-incidence wide-angle X-ray scattering.
Article
Chemistry, Applied
Jia-Xin Li, Ji-Jun Xu, Wen-Qi Luo, Chuan-Ming Jin
Summary: Three non-classical amphiphilic phenylazoimidazole derivatives were synthesized and their in-situ molecular assemblies upon coordination with AgNO3 at the air/water interface were investigated. These compounds showed good photochromic properties and formed H-aggregates on the surface despite lacking alkyl chains. The Ag(I)-coordinated 4-PRIM films exhibited supramolecular chirality due to pi-pi stacking between neighboring azophenyl imidazolium units and symmetry breaking in some systems.
Article
Biochemistry & Molecular Biology
Marek Szablewski, Richard L. Thompson, Lars-Olof Palsson
Summary: Novel fluorescent Langmuir-Blodgett (LB) films have been constructed from different amphiphilic dicynaoquinodimethanes (DADQs), and the relationship between film structure and fluorescence properties, as well as the response of the films to non-fluorescent target analytes, has been studied. The results show that the modulation of fluorescence varies for different films, which can be attributed to restricted non-radiative decays or charge transfer reactions between target analyte and film.
Article
Chemistry, Analytical
Ilya Gorbachev, Andrey Smirnov, George R. R. Ivanov, Tony Venelinov, Anna Amova, Elizaveta Datsuk, Vladimir Anisimkin, Iren Kuznetsova, Vladimir Kolesov
Summary: A sensitive coating based on Langmuir-Blodgett (LB) films containing monolayers of DPPE with immobilized GOx enzyme was created. The effect of immobilization of GOx enzyme molecules on the surface properties of a Langmuir DPPE monolayer was investigated. The sensory properties of the resulting LB DPPE film with immobilized GOx enzyme in glucose solutions of various concentrations were studied. The findings suggest that acoustic methods can be used to determine the concentration of glucose molecules in an aqueous solution, and the developed technology has potential applications in the food and pharmaceutical industries.
Article
Materials Science, Multidisciplinary
Kashan Burhan Mohamed, Somayeh Ghaderi, Rahman Hallaj, Abdollah Hassanzadeh
Summary: Two-dimensional large scale LB films of magnetic nanowires (MNWs) were prepared on glass substrates for the first time using the Langmuir-Blodgett (LB) technique. The MNWs were synthesized by template directed electrodeposition method. The successful transformation of MNWs onto the substrates demonstrated the effective assembly of MNWs using the LB technique. These results open up new opportunities for the applications of magnetic nanomaterials in physical and chemical sensors, data-storage media and magnetic switching devices.
MATERIALS SCIENCE AND ENGINEERING B-ADVANCED FUNCTIONAL SOLID-STATE MATERIALS
(2023)
Article
Polymer Science
Olga Zamyshlyayeva, Zarina Shaliagina, Maria Simonova, Alexander Filippov, Maxim Baten'kin
Summary: A novel amphiphilic block copolymer was synthesized and its colloidal chemical properties in Langmuir monolayers and Langmuir-Blodgett films were studied. The block copolymer exhibited unique characteristics in terms of film fracture pressure and morphology.
Article
Polymer Science
Yaroslav I. Derikov, Daniil R. Belousov, Alexander V. Finko, Georgii A. Shandryuk, Nina M. Kuz'menok, Sergei G. Mikhalyonok, Vladimir S. Bezborodov, Elena V. Chernikova, Raisa V. Talroze
Summary: In this study, we synthesized new vinyl ketone monomers BVK and QVK with mesogenic substituents. Compared with previously synthesized TVK, all of them can form crystals, while the ability to exhibit liquid crystalline behavior depends on the number of phenyl substituents attached to the para-position of the phenoxy group, and is observed for TVK and QVK only. These monomers can undergo self-polymerization and free radical polymerization under the action of AIBN. We also successfully conducted RAFT polymerization of BVK and TVK using asymmetrical trithiocarbonates. The synthesized poly(vinyl ketones) exhibit LC behavior and can undergo photodegradation upon UV irradiation.
Article
Chemistry, Physical
C. Breazu, O. Rasoga, M. Socol, P. Ganea, T. Tite, E. Matei, F. Stanculescu, A. Stanculescu
Summary: This study investigates the impact of carbon nanomaterials and lipids on the aggregation properties of the amyloid beta/Aβ(1-42) layers, showing that the presence of cholesterol inhibits fibril formation and the developed structures are correlated with the surface characteristics of the films.
APPLIED SURFACE SCIENCE
(2021)
Article
Chemistry, Multidisciplinary
Yong Liu, Wei-Guo Liu, Da-Bin Lin, Xiao-Ling Niu, Shun Zhou, Jin Zhang, Shao-Bo Ge, Ye-Chuan Zhu, Xiao Meng, Zhi-Li Chen
Summary: Vinylidene fluoride and trifluoroethylene (P(VDF-TrFE)) films are widely used in various applications due to their high electroactive, optical, and nonlinear optical properties. In this study, multilayer structured ultrathin films were fabricated using the Langmuir-Blodgett technique with accurate control over the thickness per layer. The films exhibited high density when the collapse pressure and optimal dipping value of P(VDF-TrFE) (25:75) were 60~70 mN/m and 15 mN/m, respectively. The surface topography and optical properties of the LB films were characterized, showing transparency in the visible and IR regions but high absorption in the UV region. The transmittance of the films ranged from 50% to 85% in the visible region and decreased linearly with the number of monolayers.
Article
Chemistry, Multidisciplinary
Alex T. O'Neil, John A. Harrison, Jonathan A. Kitchen
Summary: The paper discusses the synthesis and deposition of 4 brightly emissive lanthanide amphiphiles, which can be co-deposited to form multi-emissive ultra-thin films with two, three, and four distinct lanthanide emission profiles. This is the first reported instance of a four-component emissive Langmuir-Blodgett film.
CHEMICAL COMMUNICATIONS
(2021)
Article
Chemistry, Multidisciplinary
A. Maine, M. Encinas, J. Pavez, M. Urzua, G. Gunther, I Reyes, X. Briones
Summary: The photo-polymerization of stearyl methacrylate directly at the air-water interface was studied by measuring the pressure-area isotherm at different irradiation times. The polymerization resulted in a film with a compressed liquid phase and a higher order due to stronger packing forces. The film exhibited a solid phase-like behavior even before collapse. A solvent-free procedure to obtain a photo-polymeric film at the air-water interface was presented.
Article
Chemistry, Physical
Alfred Yeboah, Shabaab Muhammad, David Yan, Srikant Kumar Singh, Beatriz Moreno, Matthew F. Paige
Summary: Mixtures of perfluorotetradecanoic acid and arachidic acid can form structured monolayers and be deposited onto solid substrates. However, the ability to deposit multilayers in these systems has not been explored. The weak adhesion between perfluorocarbon layers and the ability of the hydrogenated fatty acid to fill void regions prevent the deposition of mixed multilayer films using traditional methods.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2022)
Article
Chemistry, Physical
Julia Bondareva, Sergey Luchkin, Sarkis Dagesyan, Alexander Egorov, Stanislav Evlashin, Oleg Lukin
Summary: This study demonstrates the formation and transfer of thin sulfonimide dendrimer films of different generations on solid surfaces, showing differences in contact angle between generations. By changing the number of naphthyl groups, the hydrophobic properties of the films can be controlled, leading to the creation of films with covalent and noncovalent bonding.
APPLIED SURFACE SCIENCE
(2021)
Article
Multidisciplinary Sciences
Kerrie A. Morrison, Laura Wood, Karen J. Edler, James Doutch, Gareth J. Price, Francoise Koumanov, Paul Whitley
Summary: Extraction of integral membrane proteins using poly(styrene-co-maleic acid) can retain the lipid bilayer surrounding the proteins. This study demonstrates efficient extraction of the mammalian insulin receptor with the copolymer but reveals a lack of functional response to insulin after extraction.
SCIENTIFIC REPORTS
(2022)
Article
Chemistry, Physical
Julien Schmitt, Vincenzo Calabrese, Marcelo A. A. da Silva, Kazi M. Z. Hossain, Peixun Li, Najet Mahmoudi, Robert M. M. Dalgliesh, Adam L. L. Washington, Janet L. L. Scott, Karen J. J. Edler
Summary: In this study, the physical properties and structural behavior of TEMPO-oxidized cellulose nanofibril (OCNF) suspensions in the presence of different surfactants were investigated using small angle neutron scattering (SANS) and rheology. Four surfactants with the same hydrophobic tail length but different headgroups were studied. The SANS results showed attractive interactions between OCNFs in the presence of anionic or zwitterionic surfactants, leading to gelation. Addition of a small amount of cationic surfactant allowed the formation of a tough gel by adsorbing onto the OCNF surface.
JOURNAL OF CHEMICAL PHYSICS
(2023)
Article
Chemistry, Physical
Ciaran Callaghan, Janet L. Scott, Karen J. Edler, Davide Mattia
Summary: The replacement of plastic microbeads with biodegradable alternatives is crucial in order to address the environmental persistence of plastics and their accumulation within the human food chain. This study explores the use of cellulose microbeads as a potential alternative, overcoming the challenges posed by the high viscosity of cellulose solutions. Through a 3D-printed rotating multi-nozzle system, cellulose jets were generated and subjected to controlled processes to create and regulate droplet sizes within the micrometre range, resulting in the continuous fabrication of cellulose microbeads with narrow size distributions in the range of 40-500 μm. This innovative method offers the production of microbeads in size ranges that were not previously achievable using existing technologies.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Polymer Science
Philip B. Yang, Matthew G. Davidson, Karen J. Edler, Niamh Leaman, Elly K. Bathke, Strachan N. McCormick, Olga Matsarskaia, Steven Brown
Summary: Small-angle neutron scattering experiments were conducted to compare the chain configurations, scaling, and effective polymer-solvent interactions of cyclic and linear polymers in different solvents. The results showed that cyclic polymers have more compact conformations and the polymer microstructure significantly influences the polymer-solvent interaction parameters.
Article
Biochemistry & Molecular Biology
Erin M. Parry, Ignaty Leshchiner, Romain Guieze, Connor Johnson, Eugen Tausch, Sameer A. Parikh, Camilla Lemvigh, Julien Broseus, Sebastien Hergalant, Conor Messer, Filippo Utro, Chaya Levovitz, Kahn Rhrissorrakrai, Liang Li, Daniel Rosebrock, Shanye Yin, Stephanie Deng, Kara Slowik, Raquel Jacobs, Teddy Huang, Shuqiang Li, Geoff Fell, Robert Redd, Ziao Lin, Binyamin A. Knisbacher, Dimitri Livitz, Christof Schneider, Neil Ruthen, Liudmila Elagina, Amaro Taylor-Weiner, Bria Persaud, Aina Martinez, Stacey M. Fernandes, Noelia Purroy, Annabelle J. Anandappa, Jialin Ma, Julian Hess, Laura Z. Rassenti, Thomas J. Kipps, Nitin Jain, William Wierda, Florence Cymbalista, Pierre Feugier, Neil E. Kay, Kenneth J. Livak, Brian P. Danysh, Chip Stewart, Donna Neuberg, Matthew S. Davids, Jennifer R. Brown, Laxmi Parida, Stephan Stilgenbauer, Gad Getz, Catherine J. J. Wu
Summary: Richter syndrome (RS), an aggressive malignancy that arises from chronic lymphocytic leukemia (CLL), has been studied to understand its genetic mechanisms. Through computational analysis of CLL-RS whole-exome sequencing data, specific somatic driver mutations, recurrent copy-number alterations, and chromosomal abnormalities were identified in RS cells. The study also revealed distinct molecular subtypes of RS and the potential use of cell-free DNA analysis for early diagnosis and monitoring.
Article
Agricultural Engineering
Yujie Mao, Alex Gerrow, Ella Ray, Nidia Diaz Perez, Karen Edler, Bettina Wolf, Eleanor Binner
Summary: This paper presents a novel and sustainable method to recover lignin from Cocoa Bean Shells (CBS) using Deep Eutectic Solvents (DES) and microwaves. The DES-extracted lignin exhibited unique structural characteristics compared with commercial Kraft lignin, indicating the potential of DES in the modification and upgrading of lignin for novel value-added products.
BIORESOURCE TECHNOLOGY
(2023)
Article
Genetics & Heredity
Arvind Ravi, Matthew D. Hellmann, Monica B. Arniella, Mark Holton, Samuel S. Freeman, Vivek Naranbhai, Chip Stewart, Ignaty Leshchiner, Jaegil Kim, Yo Akiyama, Aaron T. Griffin, Natalie I. Vokes, Mustafa Sakhi, Vashine Kamesan, Hira Rizvi, Biagio Ricciuti, Patrick M. Forde, Valsamo Anagnostou, Jonathan W. Riess, Don L. Gibbons, Nathan A. Pennell, Vamsidhar Velcheti, Subba R. Digumarthy, Mari Mino-Kenudson, Andrea Califano, John V. Heymach, Roy S. Herbst, Julie R. Brahmer, Kurt A. Schalper, Victor E. Velculescu, Brian S. Henick, Naiyer Rizvi, Pasi A. Jaenne, Mark M. Awad, Andrew Chow, Benjamin D. Greenbaum, Marta Luksza, Alice T. Shaw, Jedd Wolchok, Nir Hacohen, Gad Getz, Justin F. Gainor
Summary: Genomic and transcriptomic analysis of 393 non-small cell lung cancer patients treated with checkpoint inhibitors reveals molecular features associated with treatment response. The study analyzes data from the Stand Up To Cancer-Mark Foundation cohort, including whole exome and/or RNA sequencing, and identifies associations between molecular features and outcome, such as genomic subgroups, expression of immunoproteasome components, and tumor-intrinsic subtype. The findings demonstrate the complexity of immunotherapy outcomes and highlight the discovery potential of integrative analysis in well-curated cancer-specific cohorts.
Article
Oncology
Ignaty Leshchiner, Edmund A. Mroz, Justin Cha, Daniel Rosebrock, Oliver Spiro, Juliana Bonilla-Velez, William C. Faquin, Armida Lefranc-Torres, Derrick T. Lin, William A. Michaud, Gad Getz, James W. Rocco
Summary: Getz and colleagues used a computational approach to estimate the timing of genetic drivers in cancer types without premalignant disease, providing insights into the early progression of HPV-negative and HPV-positive head and neck squamous cell carcinoma. Their method, PhylogicNDT, accurately recapitulated the known genetic progression of HPV-negative HNSCC and revealed the previously unknown progression of HPV-positive HNSCC. By converting timing estimates to years before diagnosis, the study linked transitions to increased intratumor genetic heterogeneity and shorter overall survival. This research is important for understanding early cancer progression and developing strategies for early detection and treatment.
Article
Chemistry, Multidisciplinary
George M. Neville, Ana-Maria Dobre, Gavin J. Smith, Samantha Micciulla, Nick J. Brooks, Thomas Arnold, Tom Welton, Karen J. Edler
Summary: Mixtures of choline and geranic acid have been found to facilitate the transdermal delivery of larger pharmaceuticals, such as insulin. However, little is known about the mechanism of activity, hindering the efficient discovery of new materials. This study investigates the biophysical interactions between membrane-active deep eutectic solvents and ionic liquids with solid-supported model lipid bilayers using neutron reflectivity.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Chemistry, Inorganic & Nuclear
Oliver S. Hammond, Elly K. Bathke, Daniel T. Bowron, Karen J. Edler
Summary: This study investigated the structure of eutectic mixtures of choline chloride, urea, and water in deep eutectic solvent (DES) with the addition of cerium salt. It was found that the presence of cerium salt disrupted the structure of the solvent and made it more electrolyte-like. The coordination shell of choline showed significant differences compared to theoretical models. Additionally, the presence of percolating water clusters was observed in specific molar ratios of the solvent for the first time.
INORGANIC CHEMISTRY
(2023)
Article
Polymer Science
Gagik Ghazaryan, Alina Khmelnitskaia, Igor Bezsudnov, Aleksandra Kalinina, Elena Agina, Sergey Ponomarenko
Summary: In this study, a spring-roll actuator using commercial silicone dielectric elastomers was developed, offering a broader processing temperature range and faster response time compared to acrylate dielectric elastomers. By depositing electrodes on a pre-strained DE film, coating it with a functional organosilicone polymer composite, and rolling it around a metal spring, the interfacial adhesion between the DE and compliant electrodes was enhanced, preserving the integrity and electro-mechanical properties of the actuator.
Article
Chemistry, Multidisciplinary
Sukanya Datta, Julien Mahin, Emanuela Liberti, Iva Manasi, Karen. J. J. Edler, Laura Torrente-Murciano
Summary: This work provides new insights into the synthesis of small gold nanoparticles using a nontoxic and biodegradable eutectic mixture. The mixture acts as both a reducing and stabilizing agent, allowing for the formation of gold nanoparticles even at low ammonia concentrations. The presence of water, however, affects the speciation and stability of the gold precursor. This study has important implications for the green synthesis of nanoparticles for biomedical applications.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2023)
Article
Chemistry, Multidisciplinary
Iva Manasi, Ralf Schweins, Kun Ma, Karen J. Edler
Summary: This study investigates the nanostructure of deep eutectic solvents (DESs) composed of different sulfobetaines and camphor sulfonic acid, as well as their interactions with water and dodecane. Small angle neutron scattering experiments reveal that water and dodecane interact with the hydrophilic and hydrophobic moieties in the DES structure, causing the entire structure to swell and solvate. This research has the potential to provide new templating methods for growing inorganic or polymeric materials using DESs.
Article
Chemistry, Physical
George M. Neville, Kerrie A. Morrison, Ella R. Shilliday, James Doutch, Robert Dalgliesh, Gareth J. Price, Karen J. Edler
Summary: This study investigates the effect of end group variations on the solution behavior of SMA copolymers synthesized using RAFT polymerization. It is found that the hydrophobicity and hydrophilicity of the end group influence the self-assembly and nanodisc formation of the copolymers.
Proceedings Paper
Chemistry, Analytical
Daniil Anisimov, Anton Abramov, Victoria Chekusova, Askold Trul, Elena Agina, Sergey Ponomarenko
Summary: This work presents new results on the emerging application of electronic noses based on Organic Filed-Effect Transistor for food spoilage detection and quality estimation. The food industry requires fast, sensitive, and reusable sensors to replace time-consuming and expensive bacteriological methods.
2022 IEEE INTERNATIONAL SYMPOSIUM ON OLFACTION AND ELECTRONIC NOSE (ISOEN 2022)
(2022)
