期刊
LANGMUIR
卷 24, 期 18, 页码 9983-9988出版社
AMER CHEMICAL SOC
DOI: 10.1021/la800713z
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资金
- Technion Russell Berrie Nanotechnology Institute (RBNI)
We report the observation of bilayer fragments, some of which close to form vesicles, over a large range of pH at room temperature from mixtures of single-chain biocompatible commercially available nontoxic alkyl carboxylic surfactants after neutralization with HCl. The pH at which the morphological transitions occur is varied only by changing the ratio between two surfactants: the alkyloligoethyleneoxide carboxylate and sodium laurate. The effect of aging of the mixed surfactant systems in the pH region desired for dermatologic application (4.5 < pH < 7) is also studied. Finally, we show results of cytotoxicity studies on the surfactant mixtures.
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