☆ 4.8 Letter

Surgical research collaboratives in the UK

LANCET (2013)

期刊

LANCET

卷 382, 期 9898, 页码 1091-1092

出版社

ELSEVIER SCIENCE INC

DOI: 10.1016/S0140-6736(13)62013-9

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Medicine, General & Internal

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Academy of Medical Sciences (AMS) [AMS-SGCL7-Hall] Funding Source: researchfish
National Institute for Health Research [ACF-2011-14-003, CL-2009-18-012] Funding Source: researchfish

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Fairfield, R. J. George, M. Rahi, R. Al-Khudairi, M. Bamford, M. Chang, J. Cheng, C. Hedley, R. Joseph, B. Mitchell, L. Rothwell, A. Siddiqui, J. Smith, K. Taylor, O. Wroe Wright, S. Zaman, S. Hajiev, T. Ross, H. K. Baryan, G. Boyd, H. Conchie, L. Cox, N. Hill, K. Krishna, F. Lakin, S. Scotcher, M. Owen, E. Crisp, C. Thompson, J. Alberts, M. Asad, J. Barraclough, D. Marshall, W. Wakeford, P. Cronbach, E. Gammeri, J. Houlton, M. Hall, A. Kethees, R. Patel, M. Perera, M. Shaid, E. Webb, A. Saiyed, A. Charalambous, J. L. Hollywood, R. F. L. Hammond, S. Beattie, M. Chadwick, O. El-Taji, S. Haddad, M. Mann, K. Popat, L. Rimmer, H. Riyat, H. Smith, J. Matthews, V Mendonca, J. Spinty, N. Glynn, U. Muhammad, L. Anderson, C. Anandarajah, M. Cipparrone, K. Desai, C. Gao, E. T. Goh, M. Howlader, N. Jeffreys, A. Karmarkar, G. Mathew, H. Mukhtar, E. Ozcan, A. Renukanthan, N. Sarens, C. Sinha, A. Woolley, R. Bogle, O. Komolafe, F. Loo, D. Waugh, R. Zeng, K. Mccormack, A. Crewe, J. Mathias, A. 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Espin-Basany, D. Clerc, G. Mignon, A. Vanoni, A. Henkens, G. Jarrar, M. Odovic, M. Willemin, O. Milliet, D. Hahnloser, N. Demartines, P. Curchod, C. Ciubotaru, S. Popescu, S. S. Popescu, K. Piras, C. Ciubotaru, A. Yanishev, R. Luzan, E. Lutovinova, A. Gavrilina, A. Barkovskaya, N. Kudelkina, D. Topchubaev, B. B. Ozkan, A. Yagiz Sen, M. K. Aktas, N. Aykun, M. H. Agca, C. Bilen, I Kilinc, C. Atar, V Kilic, C. Aktuna, M. Aba, I. C. Eray, B. E. Baki, E. Arslan, G. Alemdag, M. Ulusahin, E. B. Gul, R. Yildirim, A. Semiz, G. Bektur, K. Tomas, S. Bodur, B. Yuksek, H. Serin, H. Erdonmez, F. Gursoy, H. Kara, U. Onsal, M. Ozbek, P. A. Kasar, A. Ipor, M. F. Cetin, R. A. Khaw, E. Mills, L. R. Manley, K. Vutipongsatorn, N. Thakral, M. Adra, S. M. Khan, A. Badran, A. Ramjeeawon, H. L. Tan, D. S. Rye, N. Rajaraman, J. G. Norman, G. Solomou, D. M. Baker, B. D. Brandao, B. Stainer, O. O. Onafowokan, A. Gharooni, N. Dabab, S. Carlton-Carew, G. Kungwengwe, M. Gabriel, E. Sewart, P. Pockney, A. Chrimes, A. Agarwal, J. Zhao, J. M. S. N. Jayalath, P. Liebenberg, S. Khor, T. Muddasani, A. Dawson, N. Taylor, C. Stevenson, A. Drane, U. Pahalawatta, L. T. Lai, A. Debiasio, M. Jung, C. D. Brumfitt, Y. Z. Beh, N. N. Dudi-Venkata, Y. D. Lee, P. Stewart, V Thirugnanasundralingam, K. Muir, B. Ng, D. M. Mendis, P. M. Robb, H. J. Lee, A. A. B. Wyche, L. T. Davis, J. K. Luong, ,

Summary: This study validates a prognostic model for acute kidney injury (AKI) after major gastrointestinal surgery. The model shows good predictive accuracy in two multicentre cohort studies.

BJS OPEN (2022)

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Letter Anesthesiology

CArdiovaSCulAr outcomes after major abDominal surgEry: study protocol for a multicentre, observational, prospective, international audit of postoperative cardiac complications after major abdominal surgery

Sivesh K. Kamarajah

BRITISH JOURNAL OF ANAESTHESIA (2022)

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Article Gastroenterology & Hepatology

The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study

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Martin-Perez, Calvo P. Espino, Guillamot P. Ruano, Colao L. Garcia, Diaz D. Perez, Esteban E. Agusti, Galindo P. Jara, Gutierrez M. Samaniego, Hernandez M. A. Bartolome, Serrano J. Gonzalez, Alonso A. Poza, B. Dieguez, M. Garcia-Conde, M. Hernandez-Garcia, M. Losada, E. Alvarez, N. Chavarrias, Gegundez A. Simon, Gortazar S. de Las Casas, J. Guevara-Martinez, Prieto M. Nieto, P. Ramos-Martin, I Rubio-Perez, J. Saavedra, A. Urbieta, D. Aparicio-Lopez, Cantalejo M. Diaz, De Miguel M. D. C. Ardevines, Dobon M. A. Rascon, V Duque-Mallen, Gascon Ferrer, Gonzalez-Nicolas M. T. Trebol, C. Gracia-Roche, Herrero M. Lopez, H. Kalviainen, Martinez A. German, M. Matute, Sanchez N. Fuentes, M. S. Santero-Ramirez, S. Saudi, Blazquez A. Martin, Diez M. Alonso, P. Hernandez, F. Mendoza-Moreno, Ovejero E. Merino, Vera C. Mansilla, B. Matias-Garcia, A. Quiroga-Valcarcel, A. G. Barranquero, Cerro C. Zaballos, J. Nunez, J. Ocana, D. Ramos, Acebes F. Garcia, M. Bailon-Cuadrado, Bueno A. D. Canones, Choolani E. Bhojwani, P. Marcos-Santos, T. Miguel, Pacheco D. Sanchez, B. Perez-Saborido, Sanchez J. Gonzalez, F. J. Tejero-Pintor, F. Alconchel, A. Conesa, Gil J. Martinez, Gutierrez A. Fernandez, Lopez A. Abad, T. Nicolas-Lopez, Ramirez P. Romero, Roca M. J. Calvo, K. Rodrigues, Ruiz J. J. Manzanera, A. Soriano, A. Cano, L. Capitan-Morales, Cintas J. Catena, J. Gomez-Rosado, Oliva F. Mompean, Perez M. A. Sanchez, Rio F. D. Lafuente, Torres C. Arcos, J. Valdes-Hernandez, H. Cholewa, M. Frasson, Martinez C. Chicote, J. Sancho-Muriel, B. Estraviz, Fernandez Gomez L. Cruzado, Gonzalez M. de Miguel, A. Landaluce-olavarria, A. Abad-Gurumeta, A. Abad-Motos, E. Martinez-Hurtado, J. Ripolles-Melchor, A. Ruiz-Escobar, A. Cuadrado-Garcia, Garcia-Sancho L. Tellez, Heras J. Aznar, Mate P. Mate, Ortega Vazquez, A. L. Picardo, Rojo J. A. Lopez, Sanchez Cabezudo F. Noguera, Serralta D. de Colsa, Cagigas C. Fernandez, Caina R. Ruiz, Gomez M. Ruiz, P. Martinez-Perez, Santarrufina S. Martinez, Valbuena V. Jabares, Cagigal E. P. Ortega, I Cervera, Diaz P. Pena, J. Gonzalez, Marqueta M. De Salas, Perez M. Gonzalez, Ramos A. Bonilla, Rodriguez L. Gomez, Alfonso M. Garcia, A. Craus-Miguel, Fernandez L. Vega, E. Ferrer-Inaebnit, Gil A. Catalan, Gonzalez F. X. Argente, S. Jeri, A. Oseira, Pujol N. Cano, J. J. Segura-Sampedro, Soldevila C. Verdeguer, B. Villalonga, R. Blanco-Colino, E. Espin-Basany, G. Pellino, S. Srishankar, S. P. B. Thalgaspitiya, Ali A. A. Karar, M. H. Y. Elhafiz, Adam Essa M. E. Adam, M. Saleh, S. Arkani, J. Freedman, E. Angenete, J. Park, G. Heinius, M. Nordberg, E. Pieniowski, N. Lofgren, M. Rutegard, M. Arigoni, M. Bernasconi, D. Christoforidis, M. Di Giuseppe, D. La Regina, F. Mongelli, M. Chevallay, O. Dwidar, E. Gialamas, M. Sauvain, M. Adamina, A. S. Crugnale, L. Guglielmetti, G. Peros, M. Gass, J. Metzger, A. Scheiwiller, M. Turina, T. Al Asadi, S. Alkhateb, R. Altom, B. Bakkar, Maa S. Albared, S. Melhem, A. Hammed, S. Hammed, M. J. Kacem, H. Maghrebi, A. Sebai, A. Aghayeva, I Hamzaoglu, I Sahin, E. Akaydin, Z. Aliyeva, E. Aytac, B. Baca, V Ozben, B. B. Ozmen, A. E. Arikan, I. A. Bilgin, H. Kara, T. Karahasanoglu, C. Uras, A. Akbas, Y. Altinel, F. Calikoglu, G. Ercan, C. Ercetin, S. Meric, M. Tokocin, T. Vartanoglu, H. Yigitbas, M. Dogangun, N. Iflazoglu, O. Cennet, Dincer Ha, T. Erol, A. Alhamed, S. Ergun, A. N. Sanli, S. S. Uludag, M. Velidedeoglu, A. K. Zengin, Y. Kara, M. A. Bozkurt, A. Kocatas, K. Eyuboglu, A. Guner, M. A. Usta, E. Balik, D. Bugra, C. B. Kulle, S. A. Guler, O. C. Tatar, N. Z. Utkan, A. Yildirim, E. Yuksel, A. Abbasov, H. Yanar, E. Akin, F. Altintoprak, G. Cakmak, H. Demir, E. Dikicier, N. Firat, E. Gonullu, M. B. Kamburoglu, I. F. Kucuk, B. Mantoglu, G. O. Kucuk, M. S. Uyanik, B. Goksoy, E. Bozkurt, E. Capkinoglu, O. Guven, M. Mihmanli, S. Omeroglu, M. Tanal, G. Yetkin, M. Akalin, C. Arican, E. K. Avci, C. Aydin, Demirli S. Atici, M. Emiroglu, T. Kaya, Kilinc G. Tuncer, Y. Kirmizi, S. Salimoglu, C. Tugmen, K. Tuncer, G. Uslu, A. Yildiz, Gultekin Fa, H. Lule, B. Oguttu, J. Agilinko, A. Ahmeidat, M. Bekheit, L. K. Cheung, B. S. Kamera, G. Mignot, S. Shaikh, P. Sharma, A. Al-Mohammad, S. Ali, J. Ashcroft, O. Baker, P. Coughlin, R. J. Davies, H. Kyriacou, C. Mitrofan, A. Morris, W. Raby-Smith, S. M. Rooney, A. A. Singh, X. S. Tan, A. Townson, E. Tweedle, A. Kattakayam, R. Lunevicius, A. Sheel, A. Sud, M. Sundhu, D. Angelou, M. Choynowski, B. McAree, A. McCanny, D. Neely, F. Kamel, L. Kumar, R. Madani, P. Nisar, M. Creanga, M. Elniel, J. Law, F. Mosley, L. Arrowsmith, W. Campbell, T. Grove, C. Kontovounisios, O. Warren, T. Doulias, Li M, E. Martin, H. Rodwell, R. Clifford, N. Eardley, E. Krishnan, N. Manu, Roy S. Mahapatra, O. L. Serevina, C. Smith, D. Vimalachandran, K. Emslie, Labib Pl, G. Minto, J. Natale, P. Panahi, L. J. Rogers, A. Abubakar, Akhter M. M. Rahman, H. O'Brien, K. Sasapu, H. J. Ng, A. Day, A. Hunt, N. Laskar, A. Gupta, J. Steinke, S. Thrumurthy, E. Massie, K. McGivern, D. Rutherford, M. Wilson, T. Bacarese-Hamilton, M. Ip, A. James, G. Salerno, T. Stockdale, S. Handa, M. Kaushal, A. Kler, P. Patel, J. Redfern, S. Tezas, Y. Aawsaj, C. Barry, L. Blackwell, H. Emerson, A. Fisher, M. Katory, A. Mustafa, L. Kretzmer, L. Lalou, B. Manku, I Parwaiz, J. Stafford, M. Abdelkarim, A. Asqalan, T. Gala, S. Ibrahim, A. Maw, R. Mithany, R. Morgan, Sundaram G. Venkatesan, D. Banfield, M. Boal, O. Brown, H. Dean, A. J. Boulton, C. M. Hardie, C. McNaught, S. Karandikar, D. Naumann, F. Chen, J. Cheung, J. Ayorinde, T. Chase, T. Cuming, A. Ghanbari, L. Humphreys, S. Tayeh, Aboelkassem A. Ibrahim, C. Evans, H. Ikram, M. Loubani, S. Nazir, A. Robinson, T. Sehgal, A. Wilkins, J. Dixon, M. Jha, S. Thulasiraman, Y. Viswanath, T. Curl-Roper, C. Delimpalta, C. C. L. Liao, V. Velchuru, E. Westwood, G. Bond-Smith, S. Mastoridis, G. D. Tebala, C. Verberne, N. Anscomb, R. Baldwin-Smith, M. Davies, C. Grainger, A. Haji, A. Haq, J. W. Nunoo-Mensah, M. Rizk, M. Bhatti, H. Boyd-Carson, E. Elsey, E. Gemmill, P. Herrod, M. MohammedJibreel, E. Lenzi, T. Saafan, D. Sapre, T. Sian, N. Watson, A. Athanasiou, J. Burke, F. Costigan, H. Elkadi, J. Johnstone, C. Nahm, S. Annamalai, C. Ashmore, A. Kourdouli, C. S. Chean, S. Dharamavaram, N. Kulkarni, I Pereira, K. Shanthakunalan, B. Srikumar, A. Askari, N. Cirocchi, S. Kudchadkar, K. Patel, J. Sagar, R. Talwar, M. Abdalla, O. Ismail, K. Newton, N. Stylianides, A. Aderombi, O. Bajomo, K. Beatson, W. Garrett, V Ng, R. Al-Habsi, G. S. Divya, F. Dixon, B. D. Keeler, R. J. Egan, I Fabre, R. Harries, Li Z, K. Parkins, N. Spencer, D. Thompson, C. Gemmell, C. Grieco, L. Hunt, Mahmoud F. Ali, K. Seebah, I Shaikh, L. Sreedharan, M. Youssef, J. Shah, M. Baguley, ,

Summary: This study compared the resectability of colorectal cancer patients undergoing delayed surgery versus non-delayed surgery. The results suggest that surgical delay does not compromise resectability, but may affect long-term survival.

COLORECTAL DISEASE (2022)

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Article Geriatrics & Gerontology

Trajectories of muscle quantity, quality and function measurements in hospitalized older adults

Carly Welch, Carolyn Greig, Danielle Lewis, Zeinab Majid, Tahir Masud, Hannah Moorey, Thomas Pinkney, Benjamin Stanley, Thomas Jackson

Summary: This study aimed to characterize changes in muscle quantity, quality, strength, and physical function in hospitalized older patients. The Patient-Reported Outcome Measures Information System T-score was found to be a sensitive measure of change in physical function, while changes in muscle quantity, quality, and function were not significant at the study population level.

GERIATRICS & GERONTOLOGY INTERNATIONAL (2022)

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Article Gastroenterology & Hepatology

An international assessment of surgeon practices in abdominal wound closure and surgical site infection prevention by the European Society for Coloproctology

Sharfuddin Chowdhury, Alaa El-Hussuna, Gaetano Gallo, James E. Keatley, Michael Kelly, Ana Minaya-Bravo, Liza Ovington, Francesco Pata, Gianluca Pellino, Thomas Pinkney, Luis Sanchez Guillen, Niels-Derrek Schmitz, Kerstin Spychaj, Celine H. Riess, Gabrielle van Ramshorst

Summary: This study investigated current midline closure techniques and practices for prevention of surgical site infection (SSI). The survey found that there is wide variation in abdominal wound closure techniques and SSI prevention strategies among surgeons, with little evidence of risk-stratified approaches. It is suggested that harmonization of practice and limitation of outlying techniques may lead to better outcomes for patients.

COLORECTAL DISEASE (2023)

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Article Gastroenterology & Hepatology

Happy to close? The relationship between surgical experience and incisional hernia rates following abdominal wall closure in colorectal surgery

Laurie Smith, Alexandra Coxon-Meggy, Michael Shinkwin, Julie Cornish, Alan Watkins, Greg Fegan, Jared Torkington, HART Trial Collaborators

Summary: This study aimed to assess the rates of incisional hernia (IH) at 1 year following abdominal wall closure between junior and senior surgeons in patients undergoing elective colorectal surgery. The results showed that patients closed by trainees had a higher rate of IH (20%) compared to those closed by consultants (12%). Additionally, age, sex, and closure method were identified as risk factors for IH.

COLORECTAL DISEASE (2023)

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Article Public, Environmental & Occupational Health

The costs of surgical site infection after abdominal surgery in middle-income countries: Key resource use In Wound Infection (KIWI) study

M. Monahan, J. Glasbey, T. E. Roberts, S. Jowett, T. Pinkney, A. Bhangu, D. G. Morton, A. R. de la Medina, D. Ghosh, A. O. Ademuyiwa, F. Ntirenganya, S. Tabiri, NIHR Global Res Hlth Unit Global Surg

Summary: This study aimed to assess the costs of surgical site infection (SSI) in middle-income countries. The findings showed that SSI increases healthcare costs for patients and poses a significant burden on low-resource health systems.

JOURNAL OF HOSPITAL INFECTION (2023)

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Article Dermatology

A vascular multi-arm multi-stage trial to prevent groin wound surgical site infection: A feasibility survey

Matthew A. Popplewell, Brenig L. Gwilym, Ruth A. Benson, Maciej Juszczak, David Bosanquet, Thomas D. Pinkney, Ian Chetter, Michael Wall

Summary: A survey was conducted among vascular clinicians to assess their opinion and practice on interventions to prevent groin wound surgical site infection (SSI) following arterial surgery. The majority of participants believed that groin wound SSI is a major problem and expressed willingness to use the proposed interventions. There was clinical equipoise in randomizing patients to any of the interventions versus standard care, although some reluctance was observed regarding the use of impregnated incise drapes.

INTERNATIONAL WOUND JOURNAL (2023)

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Article Geriatrics & Gerontology

Investigating the impact of fluid status on the ultrasound assessment of muscle quantity and quality in the diagnosis of sarcopenia - a multidimensional cross-sectional study

Benjamin Stanley, Carolyn Greig, Thomas Jackson, Danielle Lewis, Hannah Moorey, Zainab Majid, Tahir Masud, Thomas Pinkney, Carly Welch

Summary: The study aimed to determine the impact of fluid status on ultrasound muscle assessment in diagnosing sarcopenia. The results showed a significant correlation between fluid status and muscle quantity and quality. These findings highlight the importance of considering fluid balance in the diagnosis of sarcopenia.

BMC GERIATRICS (2023)

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Article Clinical Neurology

Predictors of Cerebrospinal Fluid Leak Following Dural Repair in Spinal Intradural Surgery

Lei Jiang, Alexandru Budu, Muhammad Shuaib Khan, Edward Goacher, Angelos Kolias, Rikin Trivedi, Jibin Francis

Summary: The effectiveness of different dural closure techniques in preventing cerebrospinal fluid leaks following surgery for intradural lesions was compared in this study. It was found that age, surgical indication, and dural closure with suture, sealant, and patch were factors associated with CSF leaks.

NEUROSPINE (2023)

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Article Public, Environmental & Occupational Health

Impact of malnutrition on early outcomes after cancer surgery: an international, multicentre, prospective cohort study

Aya M. Riad, N. I. H. R. Global Health Unit on Global GlobalSurg Collaborative, writing group Aya M. NIHR Global Hlth Unit Global Surg, Stephen R. Knight, Dhruv Ghosh, Pamela A. Kingsley, Marie Carmela Lapitan, Marie Dione Parreno-Sacdalan, Sudha Sundar, Ahmad Uzair Qureshi, Apple P. Valparaiso, Riinu Pius, Catherine A. Shaw, Thomas M. Drake, Lisa Norman, Adesoji O. Ademuyiwa, Adewale O. Adisa, Maria Lorena Aguilera, Sara W. Al-Saqqa, Ibrahim Al-Slaibi, Aneel Bhangu, Bruce M. Biccard, Peter Brocklehurst, Sorrel Burden, Kathryn Chu, Ainhoa Costas-Chavarri, Anna J. Dare, Muhammed Elhadi, Cameron J. Fairfield, J. Edward Fitzgerald, James Glasbey, Mark I. van Berge Henegouwen, J. C. Allen Ingabire, T. Peter Kingham, Ismail Lawani, Bettina Lieske, Richard Lilford, Laura Magill, Mayaba Maimbo, Janet Martin, Sonia Mathai, Kenneth A. Mclean, Rachel Moore, Dion Morton, Dmitri Nepogodiev, John Norrie, Faustin Ntirenganya, Francesco Pata, Thomas Pinkney, Rajkumar Kottayasamy Seenivasagam, Antonio Ramos-De la Medina, Tracey E. Roberts, Hosni Khairy Salem, Joana Simoes, Richard J. E. Skipworth, Richard Spence, Neil Smart, Stephen K. Tabiri, Evropi Theodoratou, Hannah Thomas, Malcolm West, John Whitaker, Thomas G. Weiser, Edwin Yenli, Ewen M. Harrison

Summary: This international study examined the impact of global nutritional state on early postoperative outcomes in patients undergoing surgery for colorectal or gastric cancer. Severe malnutrition was found to be a risk factor for 30-day mortality and major complications following elective surgery, with a greater burden in low-income and lower-middle-income countries. Therefore, there is an urgent need for global nutritional interventions to improve early outcomes in patients with gastrointestinal cancer.

LANCET GLOBAL HEALTH (2023)

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Article Geriatrics & Gerontology

Increasing frailty is associated with higher prevalence and reduced recognition of delirium in older hospitalised inpatients: results of a multi-centre study

Waleed Faheem, Julian Lin, Taran Nandra, Sarah Richardson, David Saliu, Daisy Wilson, Thomas A. Jackson, Laura Magill, Lauren McCluskey, Rita Perry, Carly Welch, Daisy Wilson, Claire Copeland, Emma L. Cunningham, Daniel Davis, Jonathan Treml, Thomas Pinkney, Terrence Quinn, Peter Nightingale, Benjamin Jelley, Victoria Gaunt, Mary Ni Lochlainn, Kumudhini Giridharan, Mustafa Alsahab, Stephen Makin, Kelli Torsney, Jane Masoli, Lindsay Ronan, Jenni K. Burton, Oliver Todd, Joanne Taylor, Ruth Willott, Natalie Cox, Roisin Healy, Nedaa Haddad, Sharan Ramakrishna, Zahid Subhan, Antonella Mazzoleni, Olga Nynaes, Jodie Crofts, Emily McNicholas, Hannah J. Robinson, Thyn Thyn, Jonathan Baillie, William McKeown, Caroline Rice, Gerrard W. Sloan, Katherine Williamson, Yasmeen Hayat, Vee Han Lim, Katie Millichamp, Amr Bazaraa, Angharad Chilton, Alexander Harbinson, John Headlam, Elisabeth Hunter, Zainab Hussain, Al Wakkass Mahmood, Liji Ng, Srividya Sundara, Felicia Tan, Alice Wheeler, Sophie Wright, Jack B. G. Baldwin, Kate O'shea, Ghazal Hodhody, Kara Mayor, Riana Patel, Shiv Bhakta, Marie Goujon, Adriana Jakupaj, James Dove, Matthew Kearney, Vincent McCormack, Kirsty Moore, Leo Pope, Hussun-Ara Shah, Megan E. Shaw, Gemma M. Smith, Ryan Love, Maya Mukundan, Muhammad Shahid, Ahmad Alareed, Karen Beharry, Ganapathy Bhat, Sanojan Bremakumar, Laurence Caines, Sandra Darko, Nisha Rai, Pedro Vila De Mucha, Phillipa Adams, Helen McDonald, Sam Mills, Frances Parry, Frances Rickard, Stuart Winearls, Rinata Farah, Robert Grange, Fiona Herbert, Elizabeth Lonsdale-Eccles, Qurrat Ul Ain, Hannah Watson, Celine Bultynck, Chiara Cavaliere, Cal Doherty, Sarah Evans, Daniel Furmedge, Annabel Hentall MacCuish, Esther Hindley, Caitlin Meyer, Emma Mullarkey, Rosamund Pullen, Aidan Ryan, Dhruv Sarma, Elaine Seymour, Katharine Stambollouian, Darmiga Thayabaran, Chenxian Wu, George Peck, Mahrukh Raza, Kapil Sahnan, Amber Dhillon, Oluwatosin O. Abiola, Catherine Bryant, Rachael Bygate, John Frewen, Isabel Greaves, Olivia Morrow, Simon Tetlow, Guy Tinson, Aayenah Yunus, Simran Bedi, Olivia Evans, Leeying Giet, Abolfazl Behbahani, Saurav Bhattacharya, Clare Hunt, Rajeev Mishra, Louise Connor, Jack Poynton, Elizabeth Deacon, Rory Durcan, Emma Fisken, Susan A. Hall, Jane Noble, Emma L. Prendergast, Ajay Macharouthu, Victoria Macrae, Emily Murphy-Ackroyd, Emily C. Rose, Nicola Watt, Mairi Blair, Eilidh R. Mackenzie, Roisin McCormack, Sophie J. Irwin, Alice Einarsson, Ming Khor, Baraa Alhadadi, Ewen Cameron, Angela Campbell, Eileen Capek, Lorna Christie, Laura Connell, Alan Cook, Jordanna Deosaran, Marianne Elliott, Elizabeth Evans, Sarah Fancourt, Sarah Henderson, Ambreen Hussain, Karen Jones, Dominic Kelly, Catherine M. McErlean, Hazel Miller, Fariha Naeem, Caroline Ostrowski, Megan Parkinson, Fadi Sami, Alison Shepherd, Lindsay Whyte, Emily Wright, Eilidh E. C. Ferguson, Michael Gallagher, Heather J. McCluskey, Louise Beveridge, Hollie A. Clements, Jasmine Hart, Neil Henderson, Su Kwan Lim, James E. Lucocq, Alison McCulloch, Adam A. Murray, Esther E. Y. Ngan, Philippa K. Traill, Amy Walter, Michael S. J. Wilson, Abigail Wrathall, Zhi Jiun Yap, Clementine Anderson, Hashem Abu-Arafeh, Ilan Gluck, Oliver Mitchell, Richard Robson, Elizabeth L. Sampson, Arunkumar Annamalai, Jamal Bhatti, Laura Briggs, Debbie Fraser, Jonathan Gui, Eleanor Leah, Natasha R. Matthews, Pryankaran Mithrakumar, Mohammad Moad, Michael Sen, Jacqui Straughan, Roxana Taranu, Kasim Usmani, Ayesha Aamir, Amaka Achara, Olugbenro Akintade, Elizabeth J. Ellis, Sneha Gurung, Chioma Iwu, Abdullah B. Khalid, Sejlo Koshedo, Shonit Nagumantry, Nader Nashed, Philip Nwabufor, Ijeoma T. Obi, Parrthiepan Visvaratnam, Edward Wu, Marc Bertagne, Peter Jackson, James Allen, Harriet Brown, Jennifer Champion, Natasha Christodoulides, Olivia Handley, Fiona E. Macdonald, Laura J. Beeley, Victoria Clayton, Aaron Kay, John Marshall, Hannah Morgan, George Naish, Sarah L. Cleaver, Jenny Evans, Abbie Morrow, Raj Amarnani, Khai L. Cheah, Claire Cushen, Amy Enfield-Bance, Martin Glasser, Suriti Govindji, Shama Mani, Jemma Gregory, Puja Jatti, Asma Khan, Helena Lee, Helen Millner, Huma Naqvi, Emily Williamson, Teresa Harkin, Bushra Khizar, Anna Lewis, Hannah Pendleton, Steve Rutter, Rohan Ahmed, Farah Coffey, Beth Hackett, Elizabeth A. M. Holmes, Ali Khan, Zeeshan Mustafa, Mark A. Bowman, James Irvine, Katherine Patterson, Sarah Horner, Ting W. Wong, Christopher Cairns, Kate Foster, Alex Hornsby, Robbie Horton, Laura Jones, Rachel King, Emily Lyon, Ani Tencheva, Faye Wilson, Lesley J. Young, Sindhoora Dama, Eleanor Giblin, Lleika Kunaselan, Olivia Lowes, Reema Menezes, Abigail Taylor, Alex Timperley, Rachel Batho, Charlotte Bell, Sammy Carter, Paul Croft, Eliza Griffiths, Giles Hall, William Hunt, Holly Jacques, Felicity Leishman, Seema Murthy, Sinead Quinn, James Reidm, Amy Walker, Stephanie A. Matthews, Ayoub Behbahani, Martin Glasser, Ana Silva Ferreira, Caroline Ashton, Swetha Byravan, Laura Cummings, Sana Faruq, Sarah Jagdeo, Philip Thomas, Karen Broadhurst, Joseph B. Wilson, Helen Bowden, Katrin Hoffman, Howell T. Jones, Charles Katz-Summercorn, Ethan Khambay, Lucy Porter, James Speed, Keziah Austin, Farrah Bahsoon, Rose Laud, Jawad Ali, Niall Fergusson, Claire Wilkes, Laura Babb, James Gaywood, Jessica Green, Ada Kantczak, Katy F. Madden, Sasha Porter-Bent, Moe Su Su San, Laxmi Babar, Helen Chamberlain, Tamsin Cricklow, Alexis Giles, Abhishek Gupta, Clare Hughes, Tammy Lee, Anum Cheema, Yathu Matheswaran, Asiodu Nneamaka, Anekea Ross, Tarunya Vedutla, Theresa J. Allain, Emily Bowen, Julie Dovey, Natalie Gaskell, Deborah Scott, Emma Stratton, Miriam Thake, Stuart Bullock, Siobhan McKay, Stephanie Radoja, Sherif Abdelbadiee, Samuel Cohen, Jane Giddings, Christopher J. Miller, Emma Mumtaz, Minal D. Patel, Vishnu Prasad, Lahiru Satharasinghe, Mark Studley, Marylin Browne, Sabrina K. Durrant, Emma Jay, Alex McQuillan, Megan Offer, Jessel Varghese, Alexander Baron, Christian Chourot, Peter Jackson, Kimberley Kirrane, Helen Rayner, Kate Tantam, Ebrahiem Tumi, Shabnam Venkat, Nisha Aggarwal, Emma Astaire, Karthik Basker, L. Berwick, Edward Bilton, Aimee-Louise Chamboult, George Chapman, Jasmine Chevolleau, Grace Fenneley, Shannelle House, Nathan Ingamells, Emilia Jewell, Vickneswaran Kalyaani, Mahum Kiani, Nagarjun Konda, Anusha Kumar, Jo Lai, Jamie Large, Joanna Livesey, Zeinab Majid, Jack McCready, Hannah Moorey, Bethan Morgan, Kirty Morrison, Alice Mosley, Adam Pailing, Sophie Pettler, Shayan Rashid, Lucy Rimmer, Danielle Scarlett, Gurpreet Sehmbi, Abigail Smith, Nina Smith, Charles Sprosen, Emily Taylor, Jemima Taylor, Connie Tse, Sophie Turton, Henry Vardon, Jasmine Virk, Sarah Warwicker, Hannah Woodman, Beth L. Woodward, Luke Wynne, Ollie Yule, Asim Ahmad, Paapa Appiah-Odame, Ciaran Barlow, Dorothy K. C. Kuek, Isabelle Nicholls, Emma Norman, Wioletta Pyc, Ashish Vasudev, Lawrence A. T. Adams, Emma Box, Chung Sien Chai, Darcy S. Wilson, Bogna Drozdowska, Emma Elliott, Adam Stirling, Martin Taylor-Rowan, Hannah Webb, Li Wong, Ahmed Abras, Muhammad Adam, Zarah Amin, Olivia Cooper, Rhianna Davies, Wan Idoracaera C. Ikhwan, Georgia R. Layton, Awolkhier Mohammedseid-Nurhussien, Sohail Shakeel, Hana Waraich, Jabed Ahmed, Katie Ball, Kwasi Debrah, Valerie Page, Zhao Xiao Bei, Hannah McCauley, David McShane, Freya Cooper, Natalie Grundmann, Michael Haley, Andre Le Poideven, Sarah B. McClelland, Emily Moore, Norman Pang, Hannah Currie, Jayne Davies-Morris, Sarah Edwards, Sureena Janagal, Rodric Jenkin, Polly Jones, Gary Kumbun, Sarah Parry, Bhavyas Tyagi, Janine Valentine, Saad Abdullah, Emmy Abu, Sarah Ahmad, Bilquis Ahmed, Hamza Ahmed, Ana Andrusca, Matthew Ansell, Thomas Arkle, Imola Bargaoanu, Charlotte Chuter, Katie Houldershaw, Jacqueline Ibanichuka, Shoaib Iqbal, Angela Kabia, Ismail Kadir, Anjli Krishan, Adam McClean, Gerry McGonigal, Pranav Mishra, Gladys Ofoche, Anna Reay, Simon M. Stapley, Adam Swietoslawski, Nihaad Syed, Karthika Velusamy, Afnan Wahballa, James Wilcockson

Summary: This study examines the impact of frailty on the rates and recognition of delirium in hospitalized older people in the United Kingdom. The results show that as frailty increases, the risk of delirium also increases, and the ability to recognize delirium decreases. This study is important for clinical practice as it provides a more nuanced measure of vulnerability to delirium and poor outcomes.

EUROPEAN GERIATRIC MEDICINE (2023)

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Review Surgery

Global guidelines for emergency general surgery: systematic review and Delphi prioritization process

J. C. Glasbey, R. Moore, A. Ademuyiwa, A. Adisa, B. Biccard, S. Chakrabortee, D. Ghosh, E. Harrison, C. Jones, M. C. Lapitan, I Lawani, D. Morton, F. Ntirenganya, M. Maimbo, J. Martin, A. Maxwell, D. Nepogodiev, T. Pinkney, A. Ramos-De la Medina, A. U. Qureshi, J. Simoes, S. Tabiri, A. Bhangu, F. A. Abantanga, A. Abass, B. Abdul-Majeed, L. Abdur-Rahman, P. Abgenorku, D. Acquah, L. Adam-Zackaria, R. Adebisi, A. Adewunmi, D. Alderson, M. Anab, N. A. Ardu-Aryee, J. Arthur, C. Dally, S. Debrah, F. Moise Dossou, T. Drake, I Fuseini, R. Ganiyu, O. J. Garden, J. Glasbey, F. Gyamfi, A. Gyedu, S. Habumuremyi, P. D. Haque, L. H. Miguelena, A. Hesse, R. Hussey, A. Imanishimwe, J. De la Croix A. Ingabire, A. Isaka, S. Knight, D. Kolbilla, R. Lilford, M. Mbambiko, R. Mittal, M. Morna, V Msosa, J. Musowoya, C. Newton, A. Nganwa, N. Nhlabathi, J. Nkrumah-Mills, G. Nyarko, B. O. Appiah, J. L. Olory-Togbe, F. Owusu, D. Ramatu, B. Ribeiro, H. K. Salem, C. Shaw, M. Smith, A. Suroy, E. Williams, E. Yenli, A. Yifieye, J. Yorke, S-D Ziblim

Summary: Through a systematic review and thematic analysis of 38 guidelines, 68 recommendations were identified and included in the first round of voting, with a total of 410 respondents (including 219 from LMICs). The final global guidelines included eight essential, one desirable, and three critically unwell patient-specific recommendations. Key recommendations covered preoperative guidance, perioperative safety checklists, postoperative care plans, and prioritization for critically unwell patients in theatre. This evidence-based process aimed to create practical and representative guidelines for EGS in resource-limited settings worldwide.

BJS OPEN (2022)

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Article Geriatrics & Gerontology

The feasibility of conducting acute sarcopenia research in hospitalised older patients: a prospective cohort study

Carly Welch, Carolyn Greig, Zeinab Majid, Tahir Masud, Hannah Moorey, Thomas Pinkney, Thomas Jackson

Summary: The study aimed to assess the feasibility of conducting acute sarcopenia research in complex populations of hospitalised older adults. Findings showed higher recruitment rates in elective surgery patients and higher completion rates for ultrasound quadriceps. Protocol adaptations are important for ensuring feasibility, and early-stage clinical research should include assessment of muscle quantity and quality.

EUROPEAN GERIATRIC MEDICINE (2022)

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