Article
Rheumatology
Jonathan C. Hill, Stefannie Garvin, Kieran Bromley, Benjamin Saunders, Jesse Kigozi, Vince Cooper, Martyn Lewis, Joanne Protheroe, Simon Wathall, Adrian Chudyk, Kate M. Dunn, Hollie Birkinshaw, Sue Jowett, Elaine M. Hay, Danielle van der Windt, Christian Mallen, Nadine E. Foster
Summary: This study aimed to test the clinical effectiveness and cost-effectiveness of risk stratification for the treatment of common musculoskeletal disorders. The results showed that risk stratification did not lead to significant improvements in pain or function, but had some impact on GP decision making and patient experience.
LANCET RHEUMATOLOGY
(2022)
Article
Medicine, General & Internal
Joshua R. Zadro, Christopher Needs, Nadine E. Foster, David Martens, Danielle M. Coombs, Gustavo C. Machado, Cameron Adams, Christopher S. Han, Christopher G. Maher
Summary: This study aims to reduce waiting times for low back pain patients in Australia's public health system through rapid stratified telehealth. A single-center trial will be conducted, with 60 low back pain patients randomized into the rapid stratified telehealth group or usual care group. The primary outcomes include the feasibility of delivering rapid stratified telehealth and evaluating its effects for future trials. Secondary outcomes include waiting times, healthcare costs, clinical outcomes, and adverse events.
Review
Anesthesiology
James A. Hall, Sue Jowett, Martyn Lewis, Raymond Oppong, Kika Konstantinou
Summary: The study establishes a decision model for stratified care in managing low back pain, showing cost-effectiveness over a 10-year period with additional quality-adjusted life years and cost savings per patient. Sensitivity analyses suggest the approach is likely to be cost-effective in all scenarios and cost saving in most.
Article
Medicine, General & Internal
Carlos Gevers-Montoro, Arantxa Ortega-De Mues, Mathieu Piche
Summary: This article describes a randomized placebo-controlled trial aiming to examine which variables linked to central sensitization may help predict the clinical response to spinal manipulative therapy (SMT) in patients with chronic low back pain (CLBP). One hundred patients will be randomized to receive either SMT or placebo SMT, and pain intensity and disability will be assessed as primary outcomes. The results of this study may provide guidance for personalized SMT treatment.
Article
Medicine, General & Internal
Yamato Tsuboi, Tomohiro Oka, Kiyomasa Nakatsuka, Tsunenori Isa, Rei Ono
Summary: The study aimed to investigate the effectiveness of workplace active rest programme on chronic low back pain among office workers, but did not show significant effects on pain intensity and secondary outcomes. Further research is needed to determine the effectiveness of active rest in improving LBP.
Article
Medicine, General & Internal
Trudy Rebbeck, Kerrie Evans, Paulo Ferreira, Darren Beales, Michele Sterling, Kim L. Bennell, Ian Cameron, Michael Nicholas, Carrie Ritchie, Gwen Jull, Julia Treleaven, Lyndal Trevena, Kathryn Refshauge, Luke Connelly, Nadine Foster, Deborah Black, Paul Hodges, Manuela Ferreira, Tim J. Shaw, Milena Simic
Summary: This multicentre randomised controlled trial aims to evaluate the effectiveness of a novel clinical PAthway of CarE program (PACE program) for musculoskeletal conditions. Participants will be stratified into low risk/high risk groups and receive either guideline-based care or referral to allied health MSK specialists. Primary and secondary outcomes will be collected over 12 months and cost-effectiveness will be assessed.
Article
Medicine, General & Internal
Sally Hopewell, David J. Keene, Ioana R. Marian, Melina Dritsaki, Peter Heine, Lucy Cureton, Susan J. Dutton, Helen Dakin, Andrew Carr, Willie Hamilton, Zara Hansen, Anju Jaggi, Chris Littlewood, Karen L. Barker, Alastair Gray, Sarah E. Lamb
Summary: This study compared the clinical effectiveness and cost-effectiveness of a progressive exercise programme with physiotherapy advice for rotator cuff disorders, and found no significant difference in improvement over 12 months. Additionally, corticosteroid injections did not provide any long-term benefits to patients with rotator cuff disorders.
Article
Medicine, General & Internal
Divya Bharatkumar Adhia, Ramakrishnan Mani, John N. J. Reynolds, Sven Vanneste, Dirk De Ridder
Summary: This pilot study aims to evaluate the feasibility, safety, and acceptability of a novel neuromodulation technique, high-definition transcranial infraslow pink noise stimulation (HD-tIPNS), in people with chronic low back pain (CLBP), and explore the trend of its effect on pain and function. The study will collect clinical and physiological data through a randomized controlled trial and analyze them descriptively and qualitatively. The findings will contribute to the development of more valuable experimental designs and treatment approaches in the future.
Article
Health Care Sciences & Services
Tjarco Koppenaal, Martijn F. Pisters, Corelien Jj Kloek, Remco M. Arensman, Raymond Wjg Ostelo, Cindy Veenhof
Summary: This study investigated the short-term effectiveness of stratified blended physiotherapy (e-Exercise LBP) on physical functioning in patients with nonspecific low back pain (LBP). The results showed that both stratified blended physiotherapy and face-to-face physiotherapy improved physical functioning, but there was no significant difference between the two interventions. In terms of secondary outcomes, stratified blended physiotherapy showed between-group differences in fear-avoidance beliefs and self-reported adherence.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2022)
Article
Anesthesiology
In Heo, Byung-Cheul Shin, Jae-Heung Cho, In-Hyuk Ha, Eui-Hyoung Hwang, Jun-Hwan Lee, Koh-Woon Kim, Me-riong Kim, So-Young Jung, Ojin Kwon, Nam-Kwen Kim, Dong-Wuk Son, Kyung-Min Shin
Summary: The study found that electroacupuncture combined with usual care was more effective than usual care alone for patients with non-acute low back pain after back surgery. This integrated treatment approach may be considered as an effective and conservative treatment option for these patients.
BRITISH JOURNAL OF ANAESTHESIA
(2021)
Review
Biochemical Research Methods
Richa Bharti, Dominik G. Grimm
Summary: Analyzing the microbiome using next-generation sequencing techniques has improved our understanding of environmental microorganisms. However, analysis is affected by experimental conditions and downstream analysis, and new sequencing technologies can impact results. This work aims to review important workflows for sequencing data and provide best-practice protocols.
BRIEFINGS IN BIOINFORMATICS
(2021)
Article
Orthopedics
Jasper D. Bier, Milou R. Kuijer, Annet de Jong, Arianne Verhagen
Summary: The predictive validity was improved by adding the item duration of the complaints and changing the cut-off values.
Article
Anesthesiology
Layana de Souza Guimaraes, Luciola da Cunha Menezes Costa, Amanda Costa Araujo, Dafne Port Nascimento, Flavia Cordeiro Medeiros, Marina Athayde Avanzi, Ernesto Cesar Pinto Leal-Junior, Leonardo Oliveira Pena Costa, Shaiane Silva Tomazoni
Summary: The study found that photobiomodulation therapy was not superior to placebo in reducing pain intensity and disability in patients with chronic nonspecific low back pain.
Article
Medicine, General & Internal
Kathrin Krueger, Julia Schmetsdorf, Maja Pavlovic, Werner Runde, Georg Zechel, Norbert Hemken, Christian Krauth
Summary: This study aims to evaluate the effects of a 12-month relapse prophylaxis program on patients with back pain following multimodal pain therapy. The intervention group and control group will be assessed, and the evaluation will be conducted on structural, process, and results quality levels. Additionally, a health economic evaluation will be performed. The study results will be disseminated in national and international journals and conference presentations.
Article
Orthopedics
Carolin Bahns, Lisa Happe, Christian Thiel, Christian Kopkow
Summary: In Germany, overall guideline adherence among physical therapists for LBP patients was 38%, with higher adherence in the treatment section than in the physical therapeutic diagnostic process. German physical therapists predominantly provide active interventions, such as exercise therapy, but also use interventions with low or conflicting evidence.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Article
Rehabilitation
Lianne Wood, Nadine E. Foster, Martyn Lewis, Gert Bronfort, Erik J. Groessl, Catherine Hewitt, Gisela C. Miyamoto, Silje E. Reme, Annette Bishop
Summary: The study aims to investigate whether using a single matched or composite outcome would impact the results of previous randomized controlled trials (RCTs) on non-specific low back pain (NSLBP) exercise. The first objective was to determine if a single matched outcome produced a greater standardized mean difference (SMD) compared to the original unmatched primary outcome SMD. The second objective was to assess if a composite measure of matched outcomes generated a greater SMD compared to the original primary outcome SMD. Exploratory secondary analyses were conducted on data from seven RCTs.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2023)
Review
Rheumatology
Roanna Burgess, Burgess Lewis, Jonathan C. Hill
Summary: This article discusses benchmarking in community and primary care musculoskeletal (MSK) services and provides recommendations. To achieve MSK benchmarking, services need to collect consistent, standardized outcomes and use a standardized method for case-mix adjustment and outlier identification.
MUSCULOSKELETAL CARE
(2023)
Review
Clinical Neurology
Alan Nagington, Nadine E. Foster, Kym Snell, Kika Konstantinou, Siobhan Stynes
Summary: This systematic review aimed to identify prognostic factors associated with outcomes following epidural steroid injection (ESI) for patients with imaging confirmed disc-related sciatica. The review found limited evidence and low quality studies regarding prognostic factors for this treatment. Future well-designed prospective cohort studies are needed to determine these factors.
EUROPEAN SPINE JOURNAL
(2023)
Article
Rheumatology
Rana S. Hinman, Sarah E. Jones, Rachel K. Nelligan, Penelope K. Campbell, Michelle Hall, Nadine E. Foster, Trevor Russell, Kim L. Bennell
Summary: This study compared the perceptions of patients who did or did not respond to a physical therapist-supported exercise and physical activity program. The study found that both responders and nonresponders had similar themes and subthemes, including engagement, personal attitudes and expectations, beliefs about osteoarthritis and exercise, importance of adherence, and perceived strength gains with exercise.
ARTHRITIS CARE & RESEARCH
(2023)
Editorial Material
Orthopedics
Nadine E. Foster, Jonathan C. Hill, Jesper Knoop
JOURNAL OF PHYSIOTHERAPY
(2023)
Article
Medicine, General & Internal
Panos Sarigiovannis, Nadine E. Foster, Sue Jowett, Benjamin Saunders
Summary: This study aims to design a "best practice" delegation framework to guide the work of clinicians in NHS physiotherapy MSK services and facilitate standardization of practice, ensuring that patients receive safe and effective treatment by the most appropriate person.
Review
Rheumatology
Melanie A. Holden, Miriam Hattle, Jos Runhaar, Richard D. Riley, Emma L. Healey, Jonathan Quicke, Danielle A. van der Windt, Krysia Dziedzic, Marienke van Middelkoop, Danielle Burke, Nadia Corp, Amardeep Legha, Sita Bierma-Zeinstra, Nadine E. Foster, STEER OA Patient Advisory Grp, OA Trial Bank Exercise Collaborative
Summary: This study conducted a meta-analysis to explore the effects of therapeutic exercise on pain and physical function in patients with knee and hip osteoarthritis. The results showed that therapeutic exercise had a small positive effect on reducing pain and improving physical function, especially in patients with higher levels of pain and disability.
LANCET RHEUMATOLOGY
(2023)
Review
Orthopedics
N. E. Foster, L. Eriksson, L. Deveza, M. Hall
Summary: This article provides a summary of key research themes and studies in the clinical osteoarthritis field, focusing on epidemiology and therapy. The review identified 11 key themes, including the importance of comorbidities in predicting OA, surgical approaches to reduce post-traumatic OA risk, the stability of OA subgroup trajectories, the lack of robust studies on surgery for OA, and the modest benefits of many therapies under evaluation. The authors also highlight the development of predictive models through big data analytics and machine learning to better match OA patients with the right treatment.
OSTEOARTHRITIS AND CARTILAGE
(2023)
Article
Rehabilitation
Megan H. Ross, Trevor Russell, Kim L. Bennell, Penny K. Campbell, Alexander J. Kimp, Nadine E. Foster, Rana S. Hinman
Summary: This study investigates the frequency, nature, and impact of technical issues during video consultations. The results show that technical issues commonly occur in video consultations, specifically with audio/video problems. However, these issues are generally minor, transient, and quickly resolved.
MUSCULOSKELETAL SCIENCE AND PRACTICE
(2023)
Article
Rehabilitation
Chris Littlewood, Maria Moffatt, Jacqueline Beckhelling, Daniel Davis, Adrian Burden, Lisa Pitt, Stacey Lalande, Catrin Maddocks, Gareth Stephens, Helen Tunnicliffe, Jessica Pawson, James Lloyd, Andrea Manca, Julia Wade, Nadine E. Foster
Summary: This study evaluated the feasibility of a future multi-centre randomised controlled trial comparing a physiotherapist-led exercise program with usual care for patients awaiting rotator cuff repair surgery. The results showed that the trial is feasible, but improvements are needed in recruitment rates, treatment fidelity, follow-up rates, and surgical planning.
MUSCULOSKELETAL SCIENCE AND PRACTICE
(2023)
Article
Public, Environmental & Occupational Health
Fiona Aanesen, Margreth Grotle, Tarjei Langseth Rysstad, Anne Therese Tveter, Alexander Tingulstad, Ida Lochting, Milada C. Smastuen, Maurits W. van Tulder, Rigmor Berg, Nadine E. Foster, Gwenllian Wynne-Jones, Gail Sowden, Egil Fors, Gunnhild Bagoien, Roger Hagen, Kjersti Storheim, Britt Elin Oiestad
Summary: This study aimed to evaluate whether adding motivational interviewing (MI) or a stratified vocational advice intervention (SVAI) could reduce sickness absence for workers on sick leave due to musculoskeletal disorders. The results showed that adding MI or SVAI did not significantly reduce sickness absence over 6 months compared to usual case management.
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
(2023)
Article
Public, Environmental & Occupational Health
Claire Hutchinson, David G. T. Whitehurst, Matthew Crocker, Kiri Lay, Lidia Engel, Julie Ratcliffe
Summary: This study aims to assess the impact of family member proxy perspective on interrater agreement with resident self-report by different cognition levels. The findings suggest that there are differences between self-reported and proxy-reported assessments of quality of life. Further research is needed to address these differences for quality assessment and economic evaluation in aged care.
HEALTH & SOCIAL CARE IN THE COMMUNITY
(2023)
Article
Health Care Sciences & Services
Julie Ratcliffe, Kiri Lay, Matthew Crocker, Lidia Engel, Rachel Milte, Claire Hutchinson, Jyoti Khadka, David G. T. Whitehurst, Brendan Mulhern, Rosalie Viney, Richard Norman
Summary: This study examines the effect of cognitive threshold on the reliability of self-reported quality of life using EQ-5D-5L in older people. The findings suggest that most older residents with an MMSE score of 24 or higher have sufficient cognitive capacity to complete the EQ-5D-5L self-report.
PATIENT-PATIENT CENTERED OUTCOMES RESEARCH
(2023)
Article
Health Care Sciences & Services
Logan Trenaman, Daphne Guh, Nick Bansback, Richard Sawatzky, Huiying Sun, Lena Cuthbertson, David G. T. Whitehurst
Summary: This study presents the first Canadian norms for the VR-12, providing valuable reference values for health utility, summary component scores, and domain scores. These norms can be used in Canadian economic models and help interpret routinely-collected data.
QUALITY OF LIFE RESEARCH
(2023)
Article
Sport Sciences
Daniel Leslie Bailey, Annette Bishop, Gareth Mccray, Nadine E. Foster, Melanie A. Holden
Summary: This study developed a new measure of adherence to exercise for musculoskeletal pain, called ATEMPT, and assessed its content validity, structural validity, internal consistency, test-retest reliability, and measurement error. The results showed that ATEMPT has good reliability and validity in patients with musculoskeletal pain.
BRITISH JOURNAL OF SPORTS MEDICINE
(2023)
