Article
Psychiatry
Nicholas Chak Lam Yung, Corine Sau Man Wong, Joe Kwun Nam Chan, Eric Yu Hai Chen, Wing Chung Chang
Summary: Psychotic disorders, including schizophrenia and non-affective psychoses, are linked to premature mortality, with patients experiencing higher rates of all-cause, natural-cause, and unnatural-cause deaths compared to the general population. Respiratory diseases, cardiovascular diseases, and cancers are the primary causes of death in these patient cohorts. Men and women with psychotic disorders have a significantly reduced lifespan, highlighting the urgent need for targeted interventions to improve their physical health.
SCHIZOPHRENIA BULLETIN
(2021)
Article
Psychology, Clinical
Ruimin Ma, Eugenia Romano, Mark Ashworth, Mohammad E. Yadegarfar, Alexandru Dregan, Amy Ronaldson, Claire de Oliveira, Rowena Jacobs, Robert Stewart, Brendon Stubbs
Summary: This study identified five clusters of multiple long-term conditions (MLTCs) among patients with serious mental illness (SMI), including substance-related, atopic, pure affective, cardiovascular, and complex multimorbidity. The study also found associations between demographic/clinical characteristics and different MLTC clusters. An integrated care model is recommended for treating MLTCs in this population.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychiatry
Alastair Macdonald, Dimitrios Adamis, Matthew Broadbent, Tom Craig, Rob Stewart, Robin M. Murray
Summary: The study found no independent relationship between levels of continuity of care and overall mortality in schizophrenia patients. However, lower levels of relationship continuity were significantly and independently related to death by self-injury.
Article
Oncology
Luigi Grassi, Elisa Stivanello, Martino Belvederi Murri, Vincenza Perlangeli, Paolo Pandolfi, Fabio Carnevali, Rosangela Caruso, Alessio Saponaro, Mila Ferri, Michele Sanza, Angelo Fioritti, Elena Meggiolaro, Federica Ruffilli, Maria Giulia Nanni, Maria Ferrara, Paola Carozza, Luigi Zerbinati, Tommaso Toffanin, Marco Menchetti, Domenico Berardi
Summary: The study found that patients with severe mental disorders in Emilia Romagna Region had a cancer mortality rate about 50% higher than the regional population, regardless of whether they had schizophrenia or bipolar disorders. The risk of cancer mortality varied by cancer type, gender, and psychiatric diagnosis.
Article
Psychiatry
Ira R. Katz, Benjamin R. Szymanski, Stephen R. Marder, Abigail Shotwell, Tyler C. Hein, John F. McCarthy, Nicholas W. Bowersox
Summary: This study aimed to evaluate the associations between the use of clozapine and other antipsychotic medications with all-cause mortality in patients with schizophrenia. The results showed that partial and decreasing clozapine coverage were associated with higher mortality rates, similar to the effects of other medications considered. Further research is needed to explore the relationship between the use of olanzapine and mortality rates, particularly in patients with diabetes.
PSYCHIATRY RESEARCH
(2022)
Article
Clinical Neurology
Joe Kwun Nam Chan, Corine Sau Man Wong, Philip Chi Fai Or, Eric Yu Hai Chen, Wing Chung Chang
Summary: The study found that schizophrenia patients with co-existing diabetes are at increased risk of excess mortality, regardless of complication burden levels. Implementation of multilevel, targeted interventions is needed to improve diabetes-related outcomes and reduce mortality gap in this vulnerable population.
EUROPEAN NEUROPSYCHOPHARMACOLOGY
(2021)
Article
Green & Sustainable Science & Technology
Elizabeth Karol, Dianne Smith
Summary: Insights into the relationship between people with impeded cognitive functioning and the built environment highlight the importance of considering how the home environment can help individuals improve their quality of life and adapt to daily living. When designing home environments for individuals with schizophrenia, special attention needs to be paid to the impact and needs of accommodation conditions.
Review
Cardiac & Cardiovascular Systems
Cedric Lemogne, Jacques Blacher, Guillaume Airagnes, Nicolas Hoertel, Sebastien Czernichow, Nicolas Danchin, Pierre Meneton, Frederic Limosin, Jess G. Fiedorowicz
Summary: Evidence suggests that cardiovascular mortality remains a major contributor to reduced life expectancy in individuals with severe mental disorders, despite potential negative cardio-metabolic effects of medications. Modifiable cardiovascular risk factors are often insufficiently addressed in clinical practice.
CURRENT CARDIOLOGY REPORTS
(2021)
Editorial Material
Medicine, General & Internal
Michael Liu, Stephen W. Hwang
Summary: The growing and diversifying homeless population faces significant social burdens and structural barriers to healthcare, leading to high morbidity and mortality rates. Providing healthcare for the homeless requires addressing intersecting health and social challenges through a combination of health-related and social interventions.
NATURE REVIEWS DISEASE PRIMERS
(2021)
Article
Medicine, General & Internal
Naomi Launders, Joseph F. Hayes, Gabriele Price, David P. J. Osborn
Summary: The study found that patients with SMI have a higher prevalence of multiple physical health conditions compared to those without SMI, especially in younger age groups. The clustering of physical health conditions in patients with and without SMI is similar, suggesting that interventions focusing on common diseases in the general population may help reduce the burden of disease in those with SMI. There is a need to address multimorbidity in younger age groups and reduce risk factors for poor physical health in people with SMI.
Article
Psychology, Clinical
Jayati Das-Munshi, Chin-Kuo Chang, Alex Dregan, Stephani L. Hatch, Craig Morgan, Graham Thornicroft, Robert Stewart, Matthew Hotopf
Summary: Regardless of ethnicity, individuals with serious mental illnesses (SMI) experience significantly reduced life expectancy at birth compared to the general population, with men diagnosed with schizophrenia-spectrum and bipolar disorders facing a loss of 14.5 years, and women 13.2 years. This trend is similar for people with depression as well, indicating that life expectancy for SMI patients is lower than the general population residing in the most deprived areas in England.
PSYCHOLOGICAL MEDICINE
(2021)
Article
Medicine, General & Internal
Wendy A. Davis, David G. Bruce, Sergio E. Starkstein, Timothy M. E. Davis
Summary: There is evidence to suggest that the coexistence of schizophrenia and type 2 diabetes leads to increased mortality. This study aimed to investigate whether the mortality gap had improved 15 years later. The results showed that the mortality rate was higher in patients with both type 2 diabetes and schizophrenia.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Health Policy & Services
Richard G. Frank, Sherry A. M. Glied, Morgan Shields
Summary: The study revealed changes in employment patterns for individuals with serious mental illness over the past 20 years, showing a decline in jobs requiring routine cognitive and manual skills, and an increase in jobs involving nonroutine cognitive skills. Employment decline in jobs requiring routine cognitive or manual skills was more significant for those with serious psychological distress, with about 75% of the decline coinciding with reduced employment levels rather than a shift towards nonroutine cognitive jobs. These patterns were more pronounced among men. Suggestions for interventions include workplace accommodations, evidence-based return-to-work programs, and early intervention programs.
PSYCHIATRIC SERVICES
(2021)
Review
Psychiatry
Marc De Hert, Victor Mazereel, Marc Stroobants, Livia De Picker, Kristof Van Assche, Johan Detraux
Summary: Research suggests that patients with severe mental illness, especially those with schizophrenia spectrum disorders, are at higher risk of death from COVID-19. However, methodological limitations may affect the accuracy of these findings.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Medicine, General & Internal
Annabel Nash, Tom Kingstone, Saeed Farooq, Jessica Tunmore, Carolyn A. Chew-Graham
Summary: This study explores healthcare professionals’ perspectives on switching antipsychotics to support physical health in individuals with severe mental illness. Differences in awareness and knowledge of antipsychotic side effects and risk profiles were observed between primary and secondary care clinicians. Collaboration between primary and secondary care may support switching antipsychotics to address physical health inequalities in individuals with severe mental illness.