Blockade of interleukin-6 signaling enhances hepatic steatosis but improves liver injury in methionine choline-deficient diet-fed mice

Overproduced interleukin 6 decreases blood lipid levels via upregulation of very-low-density lipoprotein receptor

(2009) M. Hashizume et al.   ANNALS OF THE RHEUMATIC DISEASES

Tocilizumab

(2009) Vicki Oldfield et al.   DRUGS

Increased Hepatic and Circulating Interleukin-6 Levels in Human Nonalcoholic Steatohepatitis

(2008) Anna Wieckowska et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Cell Type–Dependent Pro- and Anti-Inflammatory Role of Signal Transducer and Activator of Transcription 3 in Alcoholic Liver Injury

(2008) Norio Horiguchi et al.   GASTROENTEROLOGY

Anti-IL-6 receptor antibody increases blood IL-6 level via the blockade of IL-6 clearance, but not via the induction of IL-6 production

(2008) Yasushi Uchiyama et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Hepatic free fatty acids accumulate in experimental steatohepatitis: Role of adaptive pathways

(2008) Claire Z. Larter et al.   JOURNAL OF HEPATOLOGY

Mechanisms of hepatic steatosis in mice fed a lipogenic methionine choline-deficient diet

(2008) Mary E. Rinella et al.   JOURNAL OF LIPID RESEARCH