期刊
LAB ON A CHIP
卷 14, 期 6, 页码 1083-1086出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3lc51260f
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资金
- Academy of Finland [252215, 256394]
- University of Helsinki Funds
- European Research Council under the European Union [310892]
- Marie Curie Program (FP7-PEOPLE-IOF)
A reliable microfluidic platform for the generation of stable and monodisperse multistage drug delivery systems is reported. A glass-capillary flow-focusing droplet generation device was used to encapsulate thermally hydrocarbonized porous silicon (PSi) microparticles into the aqueous cores of double emulsion drops, yielding the formation of a multistage PSi-lipid vesicle. This composite system enables a large loading capacity for hydrophobic drugs.
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