期刊
LAB ON A CHIP
卷 14, 期 17, 页码 3165-3171出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c4lc00125g
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资金
- NIH [GM096040, HG004653]
- US Department of Education GAANN fellowship
- Microfluidics in Biomedical Sciences Training Grant [NIH T32 EB005582]
Sampling - the process of collecting, preparing, and introducing an appropriate volume element (voxel) into a system - is often underappreciated and pushed behind the scenes in lab-on-a-chip research. What often stands in the way between proof-of-principle demonstrations of potentially exciting technology and its broader dissemination and actual use, however, is the effectiveness of sample collection and preparation. The power of micro-and nanofluidics to improve reactions, sensing, separation, and cell culture cannot be accessed if sampling is not equally efficient and reliable. This perspective will highlight recent successes as well as assess current challenges and opportunities in this area.
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