期刊
LAB ON A CHIP
卷 12, 期 3, 页码 613-621出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c1lc20891h
关键词
-
类别
资金
- Defense Advanced Research Projects Agency (DARPA)
- Defense Sciences Office (DSO)
- National Science Foundation (NSF)
Reconfigurable systems, like the field-programmable gate array in electronics, have numerous advantages including cost, adaptability, robustness, and security. Despite this, few other chip-based technologies have developed equivalently ubiquitous reconfiguration methods. As a first step to applying this paradigm to channel-based microfluidics, we present here a rapid optofluidic technique to create, move, and remove arbitrary solid regions in a microfluidic flow simply by illumination with an optical pattern. While other techniques have shown the ability to manipulate individual particles using spatial light modulation, we demonstrate here the ability to create reconfigurable flow pathways and build morphable channel structures. These structures can be modified on the order of seconds using a combined photothermal and thermo-rheological effect. In addition to characterizing the effect, we also apply this technique to create dynamic traps for biomolecules, and demonstrate trapping of lambda-DNA molecules and nanoparticles, with a 25 fold suppression of diffusion.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据