4.7 Article

Towards a high-throughput label-free detection system combining localized-surface plasmon resonance and microfluidics

期刊

LAB ON A CHIP
卷 12, 期 17, 页码 3012-3015

出版社

ROYAL SOC CHEMISTRY
DOI: 10.1039/c2lc40590c

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资金

  1. Ministry of Science and Technology [2009CB930001, 2011CB933201]
  2. National Science Foundation of China [21025520, 21105018]
  3. Chinese Academy of Sciences [KJCX2-YW-M15]
  4. Novo Nordisk-CAS Research Foundation [NNCAS-2010-5]
  5. National Science Council of Taiwan [NSC-98-2113-M-005-004-MY3, NSC-98-2120-M-007-009]

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This work reports an integrated platform combining localized-surface plasmon resonance (LSPR) and microfluidic chips to carry out multiplexed and label-free protein analysis. We fabricated an optical bench to enable detection using only a laboratory UV-Vis spectrophotometer. This assay not only improves throughput, but also allows quantitative analysis.

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